Emibetuzumab (INN[1]) (LY2875358) is a humanized monoclonal antibody designed for the treatment of cancer.[2] It is in phase II trials for patients with NSCLC[3]
Monoclonal antibody | |
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Type | ? |
Source | Humanized (from mouse) |
Target | HGFR |
Clinical data | |
Other names | LY2875358 |
ATC code |
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Identifiers | |
CAS Number | |
IUPHAR/BPS | |
ChemSpider |
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UNII | |
Chemical and physical data | |
Formula | C6356H9810N1694O2014S48 |
Molar mass | 143719.12 g·mol−1 |
This drug was developed by Eli Lilly & Company.
References
edit- ^ World Health Organization (2014). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 111" (PDF). WHO Drug Information. 28 (2).
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Emibetuzumab, American Medical Association.
- ^ Camidge DR, Moran T, Demedts I, Grosch H, Di Mercurio JP, Mileham KF, et al. "A randomized, open-label, phase 2 study of emibetuzumab plus erlotinib (LY+E) and emibetuzumab monotherapy (LY) in patients with acquired resistance to erlotinib and MET diagnostic positive (MET Dx+) metastatic NSCLC".