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Preprint ARTICLE | doi:10.20944/preprints202301.0278.v1

Sorption of CO₂, CH₄ and their mixtures in Amorphous Poly(2,6-dimethyl-1,4-phenylene)oxide (PPO)

Valerio Loianno, Antonio Baldanza, Giuseppe Scherillo, Pellegrino Musto, Giuseppe Mensitieri

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: mixed gas sorption; glassy polymers; FTIR Spectroscopy; thermodynamic modelling; NRHB

Online: 16 January 2023 (08:45:02 CET)

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Working Paper ARTICLE

Modelling Sorption Thermodynamics and Mass Transport of n-Hexane in a Propylene-Ethylene Elastomer

Daniele Tammaro, Lorenzo Lombardi, Giuseppe Scherillo, Ernesto Di Maio, Navanshu Ahuja, Giuseppe Mensitieri 1

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: polyolefin elastomer; n-hexane; sorption thermodynamics; NRHB; diffusivity

Online: 8 March 2021 (16:09:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202102.0427.v1

A Molecular Interpretation of the Dynamics of Diffusive Mass Transport of Water Within a Glassy Polyetherimide

Andrea Correa, Antonio De Nicola, Giuseppe Scherillo, Valerio Loianno, Domenico Mallamace, Francesco Mallamace, Hiroshi Ito, Pellegrino Musto, Giuseppe Mensitieri

Subject: Chemistry And Materials Science, Biomaterials Keywords: molecular dynamics; diffusion; mass transport of water; polymer matrix

Online: 19 February 2021 (09:50:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0441.v1

The Time Temperature Superposition in Polymeric Rubber Gels Treated by Means of the Mode-Coupling Theory

Francesco Mallamace, Giuseppe Mensitieri, Martina Salzano de luna, Domenico Mallamace

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: viscoelasticity; relaxations; polymeric gels; dynamical arrest

Online: 5 April 2024 (13:14:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0130.v1

Interaction Solutions for the Fractional KdVSKR Equations in (1+1)-Dimension and (2+1)-Dimension

Lihua Zhang, Zitong Zheng, Bo Shen, Gangwei Wang, Zhenli Wang

Subject: Physical Sciences, Mathematical Physics Keywords: Korteweg-de Vries Sawada-Kotera-Ramani (KdVSKR) equation; extended Korteweg-deVries (KdV) equation; Sawada-Kotera (SK) equation; finite symmetry groups; Lie symmetry; exact solutions; consistent Riccati expansion (CRE); Hirota bilinear method; fractional derivatives

Online: 2 August 2024 (06:04:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201910.0254.v1

Extending the Shelf-Life of White Peach Fruit with 1-Methylcyclopropene and Aloe arborescens Edible Coating

Giuseppe Sortino, Filippo Saletta, Stefano Puccio, Dario Scuderi, Paolo Inglese, Vittorio Farina

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Prunus persica; edible coating; 1-methylcycyclopropene; Aloe spp; post-harvest quality

Online: 22 October 2019 (05:36:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0183.v1

MicroRNAs Modulation and Clinical Outcomes at 1 Year of Follow-Up After Excision of Subcutaneous Abdominal Fat in Overweight Patients with Pre-Diabetes Treated with Metformin vs. Placebo

Celestino Sardu, Maria Consiglia Trotta, Gorizio Pieretti, Gianluca Gatta, Giuseppe Ferrara, Giovanni Francesco Nicoletti, Michele D’Amico, Giuseppe Paolisso, Raffaele Marfella

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: obesity; prediabetes; inflammation; microRNAs; cardiovascular function

Online: 8 December 2020 (07:56:14 CET)

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Background: obese pre-diabetics have altered expression of cytokines, and sirtuin-1, that might influence myocardial function via microRNAs (miRs) expression. Objectives: to evaluate inflammatory/oxidative stress, miRs’ expression and cardiovascular function in obese pre-diabetics randomly assigned to metformin therapy vs. placebo vs. normo-glycemics at 12 months of follow-up. Materials and methods: eighty-three obese patients enrolled for abdominoplastic surgery, were divided in pre-diabetics (n 55), normo-glycemics (n 28), and assigned to hypocaloric diet. Pre-diabetics were randomly assigned to metformin (n 23) or to placebo (n 22) plus hypocaloric diet. Results: at enrollment, pre-diabetics obese vs. normo-glycemic presented higher values of glucose, insulin resistance (HOMA-IR), inflammatory/oxidative stress markers, miR-195 and miR-27, and lower values of sirtuin-1 (p<0.05). At 12 months of follow up, obese pre-diabetics with metformin vs. placebo experienced significant reduction of glucose values, HOMA-IR, and inflammatory/oxidative stress markers, with significant reduction of intima-media thickness (IMT), septum and posterior wall thickness, and left ventricle mass (LVM), (p <0.05). At 12 months of follow-up, obese pre-diabetics with placebo vs. normo-glycemics had higher values of inflammatory/oxidative stress markers, higher values of IMT, septum and posterior wall thickness, LVM, and myocardial performance index (MPI), (p<0.05). Obese pre-diabetics in metformin vs. placebo, and obese pre-diabetics with placebo vs. normoglycemics, had significant differences about IMT, MPI, and LVM (p<0.05). Obese pre-diabetics in metformin vs. placebo showed significant reduction of serum miR-195 and miR-27 (p<0.05). Obese pre-diabetics in metformin vs. normoglycemics showed higher expression of serum miR-195 and miR-27 ( p<0.05). Finally, we found inverse relation between IMT and insulin (R -0.351), HOMA-IR (R -0.340), miR-195 (R -0.355), miR-27 (R -0.181); between LVEF and Insulin (R -0.332), HOMA-IR (R -0.142), miR-195 (R -0.297) and miR-27 (R -0.163). We found inverse correlation between LVM and sirtuin-1 (R -0.272), Insulin (R -0.810), HOMA-IR (R-0.183), miR-195 (R -0.446) and miR-27 (R-0.433), and direct correlation with interleukin-6 (R 0.195). MPI inversely linked to miR-195 (R -0.260) and miR-27 (R -0.591). Conclusion: in obese pre-diabetics metformin therapy significantly reduces inflammation/oxidative stress, circulating miR-195 and miR-27, causing reduction of LVM, IMT and amelioration of cardiac performance.

Preprint ARTICLE | doi:10.20944/preprints202405.1458.v1

Risk of Infections Associated with the Use of Monoclonal Antibodies in Multiple Myeloma (MM)

Giuseppe Mele

Subject: Medicine And Pharmacology, Hematology Keywords: infectious diseases, Multiple Myeloma, monoclonal antibody based-strategies

Online: 23 May 2024 (08:17:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0393.v1

Urine LOX-1 and Volatilome as Promising Tools towards Early Detection of Renal Cancer

Michela Murdocca, Francesco Torino, Sabina Pucci, Manuela Costantini, Rosamaria Capuano, Chiara Greggi, Chiara Polidoro, Giuseppina Somma, Valentina Pasqualetti, Yolande Ketchanji Mougang, Alexandro Catini, Giuseppe Simone, Roberto Paolesse, Augusto Orlandi, Alessandro Mauriello, Mario Roselli, Andrea Magrini, Giuseppe Novelli, Corrado Di Natale, Federica Carla Sangiuolo

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: clear cell renal cell carcinoma (ccRCC); LOX-1 protein; volatile compounds (VOCs); prognostic biomarker; urine; gas chromatography mass spectrometer (GC/MS)

Online: 15 June 2021 (10:29:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1558.v1

Local DER Control with Reduced Loop Interactions in Active Distribution Networks

Giuseppe Fusco, Mario Russo

Subject: Engineering, Electrical And Electronic Engineering Keywords: decentralized voltage control; MIMO models; IMC technique; loops interaction; active power support to voltage regulation; robustness; simulations

Online: 26 March 2024 (13:07:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0005.v1

A Multi-year Investigation of Forchlorfenuron Effect on Fruit Quality in A. chinensis var. chinensis

Giovanni Mian, Michele Consolini, Antonio Cellini, Andrea Strano, Tommaso Mangoni, Marco Mastroleo, Irene Donati, Francesco Spinelli

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Brix; CPPU; fruit weight; firmness; kiwifruit; post-harvest

Online: 2 September 2024 (13:09:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0152.v1

Self-Cleaning Solar Mirrors Coatings: From the Laboratory Scale to Prototype Field Tests

Anna Castaldo, Emilia Gambale, Giuseppe Vitiello, Giuseppe Cara

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: solar mirrors; self-cleaning; coatings; sputtering; AlN; prototype; test on field

Online: 2 July 2024 (02:57:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0424.v1

Motor and Respiratory Tele-Rehabilitation in Long COVID-19 Patients after Hospital Discharge: An Interventional Study

Serena Cerfoglio, Federica Verme, Paolo Capodaglio, Paolo Rossi, Viktoria Cvetkova, Gabriele Boldini, Manuela Galli, Veronica Cimolin

Subject: Medicine And Pharmacology, Other Keywords: COVID-19; long COVID; rehabilitation; tele-rehabilitation; motor rehabilitation; respiratory rehabilitation

Online: 7 June 2024 (07:57:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1939.v1

Upregulation of Transferrin Receptor 1 (TfR1) at the Blood‐Brain Barrier by Valproic Acid, but Not of Glucose Transporter 1 (GLUT1) or CD98hc

Steinunn Sara Helgudottir, Kasper Bendix Johnsen, Lisa Greve Routhe, Charlotte LM Rasmussen, Maj Schneider Thomsen, Torben Moos

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: blood‐brain barrier; capillary depletion; CD98hc; cell culture; glucose transporter 1; ICP‐MS; nanoparticle; transferrin receptor; valproic acid

Online: 29 April 2024 (16:53:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0788.v1

Clinical Performance of the Gore Septal Occluder in Patent Foramen Ovale Closure in Different Septal Anatomies: 1 Year- Results From a Single-Center Experience

Giuseppe Verolino, Dario Calderone, Mara Gavazzoni, Davide Sala, Paolo Sganzerla

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: patent foramen ovale; complex PFO anatomy; GSO; long-term residual shunt

Online: 12 July 2023 (07:55:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0275.v1

SEM Morphological Analysis of Local Regional Anesthesia Needles Used for Single and Multiple Injections on the Oral Mucosa

Enzo Cumbo, Giuseppe Gallina, Pietro Messina, Giuseppe Alessandro Scardina

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: anesthesia needles; deformation; SEM; multiple injections

Online: 3 July 2024 (10:41:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0645.v1

Waste Management and Technological Advancement: Insights from Europe

Lucio Laureti, Alberto Costantiello, Fabio Anobile, Angelo Leogrande, Cosimo Magazzino

Subject: Business, Economics And Management, Economics Keywords: recycling; innovation; waste management; europe; k-means; panel data

Online: 9 August 2024 (07:32:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0501.v1

IGF-1 and IGFBP-1, Possible Predictors of Response to Lifestyle Intervention – Results from Randomized Controlled Trials

Nina M.T. Meyer, Stefan Kabisch, Ulrike Dambeck, Caroline Honsek, Margrit Kemper, Christiana Gerbracht, Ayman M. Arafat, Andreas L. Birkenfeld, Peter E. H. Schwarz, Jürgen Machann, Martin A. Osterhoff, Martin O. Weickert, Andreas F. H. Pfeiffer

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: IGF-axis; lifestyle intervention; intervention response; prediabetes

Online: 8 May 2024 (12:45:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0119.v1

Graduates, Training and Employment Across the Italian Regions

Massimo Arnone, Barbara Angelillis, Alberto Costantiello, Angelo Leogrande

Subject: Business, Economics And Management, Economics Keywords: labor force and employment; human capital; occupational choice; job satisfaction; wage differentials; public policy

Online: 4 June 2024 (07:25:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1128.v1

Sphingosine-1-Phosphate Decreases Erythrocyte Dysfunction Induced by Beta-Amyloid

Francesco Misiti, Pierluigi Diotaiuti, Giovanni Enrico Lombardo, Ester Tellone

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Sphingosine-1-phosphate; Band 3; erythrocyte; caspase-3; beta-amyloid; Alzheimer's disease

Online: 22 March 2024 (07:39:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.2316.v1

Innovation in Skills and Sustainable Development in Italian Upper Secondary Technical Education and the Professional Role of Construction, Environment, and Territory Technicians

Andrea Pompigna, Gianluigi Ferrario

Subject: Social Sciences, Education Keywords: Education for Sustainable Development (ESD); Technical and Vocational Education; Curriculum Innovation; Professional Competencies; Sustainable Mobility

Online: 30 July 2024 (00:14:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0738.v2

Application of Surface-Stress Driven Model for Higher Vibrations Modes of Functionally Graded Nanobeams

Giuseppe Lovisi, Luciano Feo, Annavirginia Lambiase, Rosa Penna

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Functionally Graded (FG) Materials; Bernoulli-Euler Nanobeams; Stress-Driven Nonlocal Model; Free Vibration Analysis; Surface Energy Effects; Higher Vibration Modes

Online: 11 January 2024 (12:23:53 CET)

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Preprint REVIEW | doi:10.20944/preprints202404.1377.v1

A Comprehensive Review on Alcohol Abuse Disorders Fatality, from Alcohol Binge to Alcoholic Cardiomyopathy

Antonina Argo, Maria Puntarello, Walter Pitingaro, Roberto Buscemi, Tommaso D'Anna, Ginevra Malta, Giuseppe Davide Albano, Stefania Zerbo

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: alcohol intake; cardiomyopathy; sudden death; arrhythmias; stroke; hypertension; gender; Takotsubo; forensic

Online: 22 April 2024 (10:28:33 CEST)

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Preprint SHORT NOTE | doi:10.20944/preprints202408.0304.v1

2-(2,6-Diisopropylphenyl)-1-methylimidazo[1,5-a]quinolin-2-ium tetrafluoroborate

Lyuben Borislavov, Iskra Z. Koleva, Vesela Lozanova, Maria Ivanova, Rumen Lyapchev

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: heterocyclic compounds; imidazolium salts; abnormal N-heterocyclic carbenes; cationic heterocycles

Online: 6 August 2024 (03:30:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0813.v1

Subthreshold Cannabidiol Potentiates Levetiracetam in the Kainic Acid Model of Temporal Lobe Epilepsy

Chiara Lucchi, Mattia Marcucci, Kawther Ameen Muhammed Saeed Aledresi, Anna-Maria Costa, Giuseppe Cannazza, and Giuseppe Biagini

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: cannabidiol; epilepsy; kainic acid; levetiracetam

Online: 12 August 2024 (14:14:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0758.v1

Topology Optimization of a Femoral Stem in Titanium and Carbon to Reduce Stress Shielding with the FEM Method

Mario Ceddia, Bartolomeo Trentadue, Giuseppe de Giosa, Giuseppe Solarino

Subject: Engineering, Bioengineering Keywords: hip prosthesis; finite element analysis; composite material; stress shielding; topological optimization

Online: 12 July 2023 (03:57:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.0058.v1

Novel Treatment Modalities of Type 1 Diabetes Mellitus: Opportunities and Challenges

Rasha Aziz Attia Salama, MohamedAnas MohamedFaruk Patni, Shadha Nasser Mohammed Ba-Hutair, Nihal Amir Wadid, Mushirabanu Sharifmiyan Akikwala

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: type1 diabetes mellitus; mesenchymal stem cells; gene therapy; pancreatic islet cell transplantation; teplizumab

Online: 3 June 2024 (09:51:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0046.v1

Assessment of Carbon Flux and Soil Moisture in Wetlands Applying Sentinel-1 Data

Katarzyna Dabrowska–Zielinska, Maria Budzynska, Monika Tomaszewska, Alicja Malinska, Martyna Gatkowska, Maciej Bartold, Iwona Malek

Subject: Environmental And Earth Sciences, Environmental Science Keywords: NEE; backscattering coefficient; LAI; soil moisture

Online: 13 September 2016 (10:12:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0002.v2

Small UAS-Based Wind Feature Identification System Part 1: Integration and Validation

Leopoldo Rodriguez Salazar, Jose A. Cobano, Anibal Ollero

Subject: Engineering, Control And Systems Engineering Keywords: wind prediction; wind estimation; UAS; wind shear; gust; multi-platform integration

Online: 18 January 2017 (09:44:54 CET)

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This paper presents a system for identification of wind features, such as gusts and wind shear. These are of particular interest in the context of energy-efficient navigation of Small Unmanned Aerial Systems (UAS). The proposed system generates real-time wind vector estimates and a novel algorithm to generate wind field predictions. Estimations are based on the integration of an off-the-shelf navigation system and airspeed readings in a so-called direct approach. Wind predictions use atmospheric models to characterize the wind field with different statistical analyses. During the prediction stage, the system is able to incorporate, in a big-data approach, wind measurements from previous flights in order to enhance the approximations. Wind estimates are classified and fitted into a Weibull probability density function. A Genetic Algorithm (GA) is utilized to determine the shaping and scale parameters of the distribution, which are employed to determine the most probable wind speed at a certain position. The system uses this information to characterize a wind shear or a discrete gust and also utilizes a Gaussian Process regression to characterize continuous gusts. The knowledge of the wind features is crucial for computing energy-efficient trajectories with low cost and payload. Therefore, the system provides a solution that does not require any additional sensors. The system architecture presents a modular decentralized approach, in which the main parts of the system are separated in modules and the exchange of information is managed by a communication handler to enhance upgradeability and maintainability. Validation is done providing preliminary results of both simulations and Software-In-The-Loop testing. Telemetry data collected from real flights, performed in the Seville Metropolitan Area in Andalusia (Spain), was used for testing. Results show that wind estimation and predictions can be calculated at 1 Hz and a wind map can be updated at 0.4 Hz. Predictions show a convergence time with a 95% confidence interval of approximately 30 s.

Working Paper ARTICLE

MzS Tools: GIS Methods and Tools for Seismic Microzonation Mapping

Giuseppe Cosentino, Francesco Pennica, Emanuele Tarquini, Giuseppe Cavuoto, Francesco Stigliano

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Python; QGIS plugin; geodatabase; Seismic microzonation; SpatiaLite.

Online: 7 September 2021 (11:53:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.0610.v1

Key Factors for A Successful Telemedicine Solution for Cardiovascular Diseases: A Systematic Review

Giuseppe Felice Russo, Ilaria Basile, Mario Ciampi, Stefano Silvestri

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Telemedicine; Heart failure; Atrial fibrillation; Hypertension; Telemonitoring

Online: 8 August 2024 (14:54:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0255.v1

Updated Risk Factors of Early Endothelial Deregulation in Type-1 Diabetes: A Meta-Analysis

Ranmali Ranasinghe, Michael Mathai, Mohammed Abdullah Alshawsh, Anthony Zulli

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: ; diabetes mellitus; type-1 diabetes; risk factors; biomarkers; therapeutic targets; meta-analysis ;

Online: 6 May 2024 (07:45:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0693.v1

miR-1 as a Key Epigenetic Regulator in Early Differentiation of Cardiac Sinoatrial Region

Carlos García-Padilla, Estefanía Lozano-Velasco, Virginio García-López, Amelia Aránega, Diego Franco, Virginio García-Martínez, Carmen López-Sánchez

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: miR-1; epigenetic regulator; cardiac sinoatrial region; molecular mechanisms; HDAC4; Calmodulin; pErk2/MAPK1; Mef2c activity; retinoic acid signaling; cardiac development

Online: 12 March 2024 (10:22:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0267.v1

Banking Stability in the Context of the ESG Model at World Level

Massimo Arnone, Lucio Laureti, Alberto Costantiello, Fabio Anobile, Angelo Leogrande

Subject: Business, Economics And Management, Finance Keywords: ESG factors; Banking Stability; Financial Performance; Bank to Capital Asset Ratio; Sustainable Finance; Risk Management

Online: 6 August 2024 (04:50:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0239.v1

The Access to Credit in the Context of the ESG Framework at Global Level

Massimo Arnone, Lucio Laureti, Alberto Costantiello, Fabio Anobile, Angelo Leogrande

Subject: Business, Economics And Management, Finance Keywords: ESG; Access to Credit; Sustainable Finance; Banking Sector; k-Means Clustering

Online: 6 August 2024 (04:48:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0775.v1

Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal

Constance Rink, Tomas Kroupa, Siddhartha A.K. Datta, Alan Rein

Subject: Biology And Life Sciences, Virology Keywords: HIV-1; packaging signal; Psi; protein-RNA interactions; binding kinetics

Online: 12 August 2024 (10:45:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0222.v1

Cultural and Creative Employment across Italian Regions

Angelo Leogrande

Subject: Business, Economics And Management, Economics Keywords: Innovation, Innovation and Invention, Management of Technological Innovation and R&; D, Technological Change, Intellectual Property and Intellectual Capital

Online: 2 April 2024 (16:06:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0793.v1

A Novel Paradigm for Controlling Navigation and Walk in Biped Robotics

Giuseppe Menga

Subject: Engineering, Control And Systems Engineering Keywords: Humanoid and Bipedal Locomotion; Legged Robots; Passive Walking; Foot Placement Estimation; Spherical Inverted Pendulum

Online: 13 March 2024 (15:53:26 CET)

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Classically the walk in biped robotics was obtained controlling balance during the whole step, i.e. guaranteeing that the pressure point under the soles always stayed in the polygon of the supporting feet. However, this assumed that the feet were able to transfer torque to the ground during the whole gait cycle. In spite of the fact that the amount of transferrable torque in the feet-ground contact is limited, it is possible only during some phases of the step, and the overall process is energetically inefficient. On the other side, starting from the passive motion of the rimless wheel falling on an inclined surface, and ending to the inverted pendulum with a compass, balance in the whole was proven in spite of dynamical instability inside each step. Along this line results of Foot Placement Estimation (FPE) in 2-D and 3-D showed how energy efficient walk was possible, emulating the human walk with a free fall on the swing foot and energy restitution at the foot collision with the ground for the next step. This model assumes pointy feet, so without torque transfer to the ground. In the realm of FPE, in previous papers the present author adopted the 3-D inverted pendulum in polar coordinates (Spherical Inverted Pendulum - SIP) to introduce omnidirectional walks with arbitrarily changing characteristics. No torque control was used during the step, i.e the pendulum was always in free fall at each step, the only control actions were at the beginning of the next step. These actions are: the change of angular velocities at the start of a new step, with respect to those given after the collision (emulating the torque action in the brief double stance period), to recover for the losses, and the preparation of the position in the frontal and sagittal planes of the swing foot for the next collision. The present paper improves this paradigm, proposing a general model to account for all characteristics of the biped and of the gait, with adding a minimum of dynamical complexity with respect to the SIP. This model allows, not only to walk omnidirectionally on a flat surface, but also to go up and down staircases.

Preprint ARTICLE | doi:10.20944/preprints202403.0005.v1

Early Weigth-Bearing Using Narrow Symmetrical Distal Fibular Plate

Domenico Tigani, Corrado Maria Leonida, Giuseppe Mobilia, Cesare Donadono, Alessandro Ortolani, Giuseppe Melucci, Stefano Stallone

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: closed ankle fractures; distal fibular fractures; early weight-bearing

Online: 1 March 2024 (07:43:30 CET)

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Preprint REVIEW | doi:10.20944/preprints202407.0919.v1

Ketogenic Interventions in Autosomal Dominant Polycystic Kidney Disease: A Comprehensive Review of Current Evidence

Carla Pezzuoli, Giuseppe Biagini, Riccardo Magistroni

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: ADPKD; ketogenic diet; ketosis; kidney cysts; PKD; renal function decline

Online: 11 July 2024 (04:52:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0989.v1

Application of the Generalized Double Reduction Method to the (1+1)-Dimensional Kaup-Boussinesq (K-B) System: Exploiting Lie Symmetries and Conservation Laws

Molahlehi Charles Kakuli

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Generalized double reduction method; conservation laws; Kaup-Boussinesq system; Lie symmetry analysis, exact solutions

Online: 12 September 2024 (13:03:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0802.v1

Shoulder and neck pain in swimmers: front crawl stroke analysis, correlation with the symptomatology in 61 masters athletes and short literature review.

Giuseppe Rinonapoli, Paolo Ceccarini, Francesco Manfreda, Giuseppe Rocco Talesa, Simonetta Simonetti, Auro Caraffa

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: freestyle; swimming; cervical; video; older

Online: 10 August 2023 (09:18:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1377.v1

IoTwins: Implementing Distributed and Hybrid Digital Twins in Industrial Manufacturing and Facility Management Settings

Paolo Bellavista, Giuseppe Di Modica

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: Digital Twins; Industry 4.0, IoT; IIoT; RAMI 4.0; Orchestration; TOSCA; Cloud continuum; Edge; Predictive maintenance

Online: 18 January 2024 (07:21:09 CET)

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Preprint SHORT NOTE | doi:10.20944/preprints202408.0158.v1

8-(2-Мethoxyphenyl)-6-methyl-2-(1-methyl-1Hbenzo[d]imidazol-2-yl)quinoline

Maria H. Ivanova, Joana Zaharieva, Martin Tsvetkov, Vesela Lozanova, Bernd Morgenstern, Rumen Lyapchev

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: quinoline; benzimidazole; fluorescence; single crystal diffraction; Suzuki reaction

Online: 2 August 2024 (12:03:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0022.v1

Mixing Time—Experimental Determination and Applications to the Modelling of Crystallisation Phenomena

Dragan D. Nikolić, Giuseppe Cogoni, Patrick Frawley

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: mixing time; LIF; CFD; SPH; stirred tank

Online: 3 November 2016 (09:22:18 CET)

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Performing optimisation and scale-up studies of crystallisation systems requires accurate and computationally efficient mathematical models. The assumption of the ideal mixing conditions in batch reactors typically produce inaccurate results while the computational expense of CFD models is still prohibitively high. Therefore, in this work, a new intermediary approach is proposed that takes into account the non-ideal mixing conditions in the reactor and requires less computational resources than full CFD simulations. Starting with the Danckwerts concept of the intensity of segregation, an analogy between its application to chemical reactions and the kinetics of the crystallisation phenomena (such as nucleation and growth) has been made. As a result, the modified kinetics expressions have been derived which incorporate the effect of non-idealities present in stirred reactors. This way, based on the experimental measurements of the mixing time using the Laser Induced Fluorescence (LIF) technique, computationally more efficient mathematical models can be developed in two ways: (1) the accurate semi-empirical correlations are available for standard mixing configurations with the most often used types of impellers, (2) CFD simulations can be utilised for estimation of the mixing time; in this case it is necessary to simulate only the mixing process. The benefits offered by the LIF experimental technique have been demonstrated and some frequent problems in its application analysed. The mixing time results for configurations with and without baffles for three types of impellers and four different rotational speeds have been presented. The false shorter mixing times in the non-baffled configurations have been observed and this phenomena explained by the existence of two segregated zones in the reactor and confirmed by additional experiments. The precise measurements in these cases have been shown as difficult using the LIF technique, particularly for higher rpms. The experimental data has been compared to the preliminary simulation results obtained from the Smoothed Particle Hydrodynamics method and the standard k-ε turbulence model with the modest success. The shortcomings of the SPH model have been recognized and the directions for the future work discussed.

Preprint ARTICLE | doi:10.20944/preprints201910.0350.v1

On The Dynamics of a System of Difference Equations x_n+1= x_n-1y_n- 1, y_n+1= y_n-1z_n- 1, z_n+1= z_n-1x_n- 1

Erkan Taşdemir, Yüksel Soykan

Subject: Computer Science And Mathematics, Mathematics Keywords: difference equations; dynamical systems; periodicity; stability; boundedness

Online: 30 October 2019 (07:25:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.1131.v1

Banking Stability in the ESG Framework Across Italian Regions

Massimo Arnone, Angelo Leogrande, Alberto Costantiello, Lucio Laureti

Subject: Business, Economics And Management, Economics Keywords: Sustainability; ESG; non performing loans; SMEs; clustering

Online: 15 July 2024 (08:07:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0060.v1

A Polyphenol Rich Extract from Solanum melongena L. DR2 Peel Exhibits Antioxidant Properties and Anti-Herpes Simplex virus Type 1 Activity In Vitro

Antonella Di Sotto, Silvia Di Giacomo, Donatella Amatore, Marcello Locatelli, Annabella Vitalone, Chiara Toniolo, Giuseppe Leonardo Rotino, Roberto Lo Scalzo, Anna Teresa Palamara, Maria Elena Marcocci, Lucia Nencioni

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: eggplant peel; polyphenols; HSV-1; Warburg effect; antioxidant activity; antiviral agents; vegetable waste

Online: 3 August 2018 (04:53:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0806.v1

Active Surveillance in the Management of Ductal Carcinoma in Situ: The Radiologist’s Point of View

Luca Nicosia, Giuseppe di Giulio, Anna Carla Bozzini, Marianna Fanizza, Francesco Ballati, Anna Rotili, Matteo Lazzeroni, Antuono Latronico, Francesca Abbate, Giuseppe Renne, Francesca Addante, Marco Lucioni, Enrico Cassano, and Mauro Giuseppe Mastropasqua

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Ductal carcinoma in situ (DCIS); Invasive Breast Carcinoma; Underestimation; Upgrade Rate; Vacuum assisted breast biopsy (VABB); Breast Microcalcifications; Active Surveillance.

Online: 31 December 2020 (12:52:08 CET)

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Preprint REVIEW | doi:10.20944/preprints201709.0146.v2

Role of LFA-1 and ICAM-1 in Cancer

Manuel Reina, Enric Espel

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: cancer metastasis; chronic lymphocytic leukemia; exosomes; tumor microenvironment

Online: 29 September 2017 (03:17:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0014.v1

Conservation Laws and Travelling Wave Solutions for Double Dispersion Equations in (1+1) and (2+1) Dimensions

Maria Luz Gandarias, Maria Rosa Duran, Chaudry Masood khalique

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: conservation laws; Lie symmetries; exact solutions

Online: 3 February 2020 (05:15:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.1203.v1

Social Trust and Support Networks: A Regional Analysis of Italy

Massimo Arnone, Angelo Leogrande, Carlo Drago, Alberto Costantiello

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: Altruism; Social Trust; k-Means; Machine-Learning; Silhouette Coefficient; Elbow Method; Panel Data; Regional Disparities

Online: 17 September 2024 (06:11:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0115.v1

Endogenous Innovation and Export Performance in Firms

Oliviero Antonio Carboni, Giuseppe Medda

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: European firms; R&; D; innovation; export; IV and fractional response model

Online: 7 March 2023 (01:32:45 CET)

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Preprint REVIEW | doi:10.20944/preprints201608.0097.v1

The Vulnerability of Rice Value Chains in Sub-Saharan Africa: A Review

Fanen Terdoo, Giuseppe Feola

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: vulnerability; resilience; rice value chains; climate change; Sub-Saharan Africa

Online: 9 August 2016 (12:09:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0374.v1

Financial Stability and Innovation: The Role of Non-Performing Loans

Massimo Arnone, Alberto Costantiello, Angelo Leogrande, Cosimo Magazzino

Subject: Business, Economics And Management, Finance Keywords: Non-Performing Loans; Banking stability; Innovation; k-Means

Online: 6 August 2024 (12:36:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1469.v1

Radiological Changes in Spinal Cord and Brain of Patients with HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)

Emily H Stack, Serhat V Okar, Tianxia Wu, Mallory Stack, Yair Mina, Maria I Gaitan, Shila Azodi, William Frazier, Joan Ohayon, Irene Cortese, Daniel S. Reich, Govind Nair, Steven Jacobson

Subject: Public Health And Healthcare, Other Keywords: central nervous system atrophy; spinal cord atrophy; white matter hyperintensities; magnetic resonance imaging; HTLV-1-associated myelopathy

Online: 21 August 2024 (10:16:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1140.v2

The Surprises of Molecular Testing in Neurofibromatosis Type 1: Rare Association between Two Mutational Variants

Aurora Jurca, Codruta Diana Petchesi, Maria Claudia Jurca, Diter Atasie, Dan Bembea, Alexandru Daniel Jurca

Subject: Medicine And Pharmacology, Other Keywords: neurofibromatosis type 1; cone-rod dystrophy; molecular diagnosis; rare association

Online: 12 April 2024 (14:32:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0380.v1

Relationship of SOD-1 Activity in Metabolic Syndrome and/or Frailty Elderly Individuals

Sylwia Dzięgielewska-Gęsiak, Ewa Wysocka, Edyta Fatyga, Małgorzata Muc-Wierzgoń

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: aging; metabolic syndrome; frailty syndrome; SOD-1

Online: 6 August 2024 (06:54:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1498.v1

Characterization of the Bax inhibitor-1 Family in Cauliflower and Functional Analysis of BobBIL4

Xin Liu, Ning Guo, Shasha Li, Mengmeng Duan, Guixiang Wang, Mei Zong, Shuo Han, Zhihan Wu, Fan Liu, Junjie Zhang

Subject: Biology And Life Sciences, Horticulture Keywords: Cauliflower; Bax inhibitor-1; Expression pattern; BobBIL4; Abiotic stress

Online: 21 August 2024 (00:12:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0204.v1

Methadone Maintenance and QT-interval: Prevalence and Risk Factors. Is it Effective to Switch Therapy to Levomethadone?

Laura Santin, Giuseppe Verlato, Ahmad Tfaily, Roberto Manera, Giuseppe Zinfollino, Francesca Fusina, Lugoboni Fabio

Subject: Medicine And Pharmacology, Internal Medicine Keywords: Methadone; levomethadone; QTc; prolongation; treatment; heroin; therapy-switch

Online: 2 June 2023 (12:24:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.0792.v1

A Simple Method to Identify on Patients the Implant Sites in Totally Edentulous Arches: A Pilot Study with Thermo-Printed Templates Used with CBCT

Enzo Cumbo, Giuseppe Gallina, Pietro Messina, Giuseppe Alessandro Scardina

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Implantology; implant site identification; freehand technique

Online: 12 December 2023 (06:51:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202304.0715.v1

Analysis of Accuracy in Clinical Identification of the Implant Site: Pilot Study With Thermo-Printed Templates

Enzo Cumbo, Giuseppe Gallina, Pietro Messina, Giuseppe Alessandro Scardina

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Implantology; implant site; thermo-printed templates

Online: 21 April 2023 (10:11:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0121.v2

Two Finite Mirror-Image Series Restrict the Non-Trivial Zeros of Riemann’s Zeta Function to Re(s) = 1/2 and the Zeros of its Derivative to Re(s) > 1/2

Anthony Lander

Subject: Computer Science And Mathematics, Mathematics Keywords: Riemann Hypothesis; Dirichlet eta function; Zeta function; prime numbers; number theory; critical-line; critical-strip; symmetry breaking

Online: 22 March 2017 (04:48:57 CET)

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Preprint REVIEW | doi:10.20944/preprints202405.1955.v1

Preparing for patient-customized N-of-1 Antisense Oligonucleotide Therapy to Treat Rare Diseases

Harry Wilton-Clark, Eric Yan, Toshifumi Yokota

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Antisense oligonucleotide; N-of-1; milasen; atipeksen; valeriasen; rare disease; exon skipping; splice switching; personalized medicine; muscular dystrophy

Online: 29 May 2024 (12:08:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0407.v1

Analytical Solutions and Case Studies on Stress-Dependent Corrosion in Pressurized Spherical Vessels

Cheng Huijuan Liu, Giuseppe Lacidogna

Subject: Engineering, Civil Engineering Keywords: pressure vessels; mechanically-assisted corrosion; variable boundary; analytical solution, stress; thickness; life

Online: 7 October 2023 (09:41:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0433.v1

Prevalence of Alpha-1 Antitrypsin Deficiency Alleles in a Lithuanian Cohort of Wheezing Small Children

Edita Poluzioroviene, Joanna Chorostowska-Wynimko, Sigita Petraitiene, Arunas Strumila, Adriana Roży, Aneta Zdral, Arunas Valiulis

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Alpha-1 Antitrypsin deficiency; children; wheeze; SERPINA1; COPD

Online: 4 July 2024 (11:04:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0037.v1

Effect of Orally Administered Relaxin in Experimental Nash

Giuseppe Colucci

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Extrac cellular matrix; Relaxin; liver fibrosis; MMPs

Online: 3 March 2020 (11:16:49 CET)

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Preprint REVIEW | doi:10.20944/preprints202404.1538.v2

Is the Myasthenia Gravis (MG) the Result of Age and Sex/Gender? A Narrative Review for Identifying Genetic and Epigenetic Biomarkers for a Differential MG Management in Old and Young Women

Giuseppe Schirò, Tiziana Colletti, tommaso piccoli, paolo ragonese, giuseppe salemi, Carmela Rita Balistreri, marco d'amelio

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Myasthenia gravis (MG); age and sex/gender; two different forms; genetic and epigenetic factors

Online: 30 April 2024 (11:46:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1466.v1

Molecular-scale liquid density fluctuations and cavity thermodynamics

Attila Tortorella, Giuseppe Graziano

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: density fluctuations; maximum entropy principle; Gaussian distribution; cavity distribution; solvent-excluded volume effect.

Online: 21 June 2024 (11:30:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0432.v1

Interleukin-4 (IL-4), Plasminogen Activator Inhibitor-1 (PAI-1) or Receptor for Advanced Glycation End-Products (RAGE) in Bronchial Secretions Cannot Predict Pediatric Ventilator-Associated Pneumonia (VAP)

Argyro Ftergioti, Maria Simitsopoulou, Maria Sdougka, Styliani-Antonia Kallou, Anna-Bettina Haidich, Christina Virgiliou, Georgios Theodoridis, Emmanuel Roilides, Elias Iosifidis

Subject: Medicine And Pharmacology, Internal Medicine Keywords: ventilator-associated pneumonia; biomarkers; pediatric intensive care unit; critically-ill children; ventilator-associated pneumonia; biomarkers; pediatric intensive care unit; critically-ill children

Online: 4 July 2024 (11:00:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1958.v1

Caveolae with GLP-1 and NMDA Receptors as Crossfire Points for the Innovative Treatment of Cognitive Dysfunction with Neurodegenerative Diseases

Moeka Nakashima, Naoko Suga, Sayuri Yoshikawa, Satoru Matsuda

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: caveolae; caveolin; glucagon-like peptide-1; NMDA; autophagy; mitophagy; cognitive dysfunction; Alzheimer's disease

Online: 24 July 2024 (11:52:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0525.v1

Nuclear Matter in 1+1 Dimensions

Robert Douglas Pisarski, Alexei Tsvelik, Marton Lajer, Robert M Konik

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: dense QCD; quarkyonic; Luttinger liquid

Online: 30 September 2021 (15:30:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1824.v1

Dipeptidyl Peptidase 9 (DPP9) Depletion From Hepatocytes in Mice Retards Liver Tumour Growth and Increases Intrahepatic Caspase-1 Activation

Jiali Carrie Huang, Xinlin Linda Tong, Michelle Sui Wen Xiang, Badwi B. Boumelhem, Diarmid P Foulis, Mingchang Zhang, Catriona McKenzie, Geoffrey William McCaughan, Thomas Reinheckel, Hui Emma Zhang, Mark Douglas Gorrell

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: dipeptidyl peptidase 9; serine protease; hepatocellular carcinoma; inflammasome; autophagy; histopathology

Online: 29 March 2024 (08:34:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0203.v1

The Renunciation of Healthcare Services in the Italian Regions in the ESG Context

Angelo Leogrande, Emanuela Resta, Alberto Costantiello

Subject: Business, Economics And Management, Economics Keywords: Analysis of Health Care Markets; Health Behaviours; Health Insurance; Public and Private; Health and Inequality; Health and Economic Development; Government Policy; Regulation; Public Health

Online: 5 March 2024 (09:09:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints201710.0018.v1

Challenges and Opportunities for Visualization and Analysis of Graph-Modeled Medical Data

Giuseppe Agapito, Pietro Hiram Guzzi, Mario Cannataro

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Biological Network; Graphs; Statistical Analysis

Online: 3 October 2017 (16:52:13 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202405.0314.v1

Mortality for Laryngeal Cancer before and during the COVID-19 Pandemic

Riccardo Nocini, Giuseppe Lippi, Camilla Mattiuzzi

Subject: Medicine And Pharmacology, Otolaryngology Keywords: Mortality; COVID-19; Laryngeal cancer; Larynx cancer

Online: 6 May 2024 (12:17:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202001.0174.v1

The Potential of Computational Modeling to Predict Disease Course and Treatment Response in Patients with Relapsing Multiple Sclerosis

Francesco Papparlardo, Giulia Russo, Marzio Pennisi, Giuseppe Alessandro Parasiliti Palumbo, Giuseppe Sgroi, Santo Motta, Davide Maimone

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: computational modeling; agent based modeling; systems biology; multiple sclerosis; immunity; degenerative disease.

Online: 16 January 2020 (12:00:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.1268.v1

Is Water the Engine of Protein Folding?

Marco Campanile, Giuseppe Graziano

Subject: Biology And Life Sciences, Biophysics Keywords: water; globular proteins; folding; hydrophobic effect

Online: 17 September 2024 (08:16:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0883.v1

NR5A1/SF-1 Collaborates with Inhibin α and the Androgen Receptor to Reveal a Complex DSD Phenotype

Rawda Naamneh Elzenaty, Chrysanthi Kouri, Idoia Martinez de Lapiscina, Kay Sara Sauter, Francisca Moreno, Núria Camats Tarruella, Christa E. Flück

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: steroidogenic factor 1 (SF-1/NR5A1); inhibin , androgen receptor; differences of sex development (DSD); 46,XY DSD; hypospadias; oligogenicity

Online: 14 August 2024 (09:17:30 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.1442.v1

The Dark Side of Nosocomial Infections in Critically Ill COVID-19 Patients

Carmelo Biondo, Elena Ponzo, Angelina Midiri, Giuseppe Bernardo Ostone, Mancuso Giuseppe

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: COVID-19; co-infection; secondary infection; multidrug resistance; alternative strategies

Online: 19 May 2023 (12:02:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0152.v1

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Massimo Sangiorgi, Mariangela Valentina Puci, Allegra Rosa Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco Michelino Fiore, Armado Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Pietro Modugno, Maurizio Maiorano, Umberto Marcello Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni Maria Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio Stefano Tolva, Ilenia D'Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D'Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio Massimo Oddi, Alberto Maria Settembrini

Subject: Medicine And Pharmacology, Hematology Keywords: chronic limb-threatening ischemia; outcome; sex; age; limb salvage

Online: 8 December 2022 (09:39:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202101.0019.v1

Renal Cell Carcinoma Intravascular Spread Into Segmental Branches of the Renal Vein: A Single Institution Case Series

Mauro Giuseppe Mastropasqua, Marta Mariano, Federico Fusco, Gerardo Cazzato, Valentina Ruggiero, Michele Battaglia, Giuseppe Lucarelli, Giuseppe Ingravallo, Eugenio Maiorano

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Renal Cell Carcinoma; Pathological staging; Extrarenal extension; Renal vein invasion

Online: 4 January 2021 (11:31:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0069.v1

Fires Monitoring by Means of Spectral Indices from Sentinel-2 Data: the Case Study of the Vesuvius and Lattari Mountains, Campania (Italy)

Domenico Antonio Giuseppe Dell'Aglio, Carmine Gambardella, Massimiliano Gargiulo, Antonio Iodice, Rosaria Parente, Daniele Riccio, Giuseppe Ruello

Subject: Engineering, Automotive Engineering Keywords: fire monitoring; Sentinel-2; time series; Italy wildfires; active fire detection; pre-fire analysis; burned area mapping

Online: 3 September 2020 (15:40:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0210.v2

Automated Identification of Discrepancies between Nautical Charts and Survey Soundings

Giuseppe Masetti, Tyanne Faulkes , Christos Kastrisios

Subject: Engineering, Marine Engineering Keywords: nautical cartography; chart adequacy; change detection; triangulated irregular network; safety of navigation; ocean mapping

Online: 26 September 2018 (05:40:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0611.v1

Doxycycline and Minocycline act as Positive Allosteric Modulators of the PAC1 Receptor and Induce Plasminogen Activators in RT4 Schwann Cells

Sarah Thomas Broome, Giuseppe Musumeci, Alessandro Castorina

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: pituitary adenylate cyclase-activating peptide (PACAP); PAC1 receptor; doxycycline; minocycline; positive allosteric modulator; Schwann cells; tissue plasminogen activator (tPA); urokinase plasminogen activator (uPA)

Online: 27 July 2021 (21:51:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0433.v1

Astrosat SXT X-ray Spectrum Changes over the 35-Day Cycle in Hercules X-1

Denis Leahy, Riddhiman Sharma

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: binaries; eclipsing — star; neutron— stars; individual (HZ Her/ Her X-1)

Online: 7 June 2024 (08:00:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0531.v1

An Explorative Application of Multilayer Networks and Pathway Analysis in Pharmacogenomics

Marianna Milano, Giuseppe Agapito, Mario Cannataro

Subject: Computer Science And Mathematics, Computer Science Keywords: pharmacogenomics; network analysis; multilayer networks; community detection; pathway enrichment analysis

Online: 7 September 2023 (11:49:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1615.v2

Adherence to Antiretroviral Therapy (ART) Among HIV-1 Patients From Sub-Saharan Africa: A Systematic Review

Pedro Almeida, Carlos Rafael, Victor Pimentel, Ana Abecasis, Cruz Sebastião, Joana Morais

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: HIV-1; Antiretroviral therapy; Treatment adherence; sub-Saharan Africa.

Online: 29 April 2024 (03:59:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0006.v1

Association of JAK2 Haplotype GGCC_46/1 with the Response to Onco-Drug in MPNs Patients Positive for JAK2V617F Mutation

Michela Perrone, Sara Sergio, Amalia Tarantino, Giuseppina Loglisci, Rosella Matera, Davide Seripa, Michele Maffia, Nicola Di Renzo

Subject: Biology And Life Sciences, Life Sciences Keywords: JAK V617F mutation; JAK2 haplotype GGCC_46/1; Myeloproliferative neoplasm

Online: 1 August 2024 (11:04:23 CEST)

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Preprint SHORT NOTE | doi:10.20944/preprints202311.0970.v1

1-(2,5-Dimethoxy-4-nitrophenyl)piperidine and 1-(2,5-dimethoxy-4-nitrophenyl)pyrroridine

Tanjia M. Syeda, Muadh R. Al-Shaidi, Ibtihal Basri, Mahboub Merzouk, Fawaz Aldabbagh

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: benzimidazolequinone, nitration; nitrobenzene; nucleophilic aromatic substitution

Online: 15 November 2023 (09:06:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0546.v1

Companies with at Least 10 Employees Selling Online across the Italian Regions

Angelo Leogrande

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: Innovation; Innovation and Invention; Management of Technological Innovation and R&; D; Technological Change; Intellectual Property and Intellectual Capital

Online: 8 April 2024 (16:06:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0299.v1

Regular Internet Users across the Italian Regions

Angelo Leogrande

Subject: Business, Economics And Management, Economics Keywords: Innovation; Innovation and Invention; Management of Technological Innovation and R&; D; Technological Change; Intellectual Property and Intellectual Capital

Online: 3 April 2024 (12:43:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1580.v1

Knowledge Workers in the Italian Regions

Angelo Leogrande

Subject: Business, Economics And Management, Economics Keywords: Innovation; Innovation and Invention; Management of Technological Innovation and R&; D; Technological Change; Intellectual Property and Intellectual Capital

Online: 26 March 2024 (11:24:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1034.v1

Incident Cancer Risk in Patients With Incident Type 2 Diabetes Mellitus in Hungary (Part 1)

Zsolt Abonyi-Tóth, György Rokszin, Ibolya Fábián, Zoltán Kiss, György Jermendy, Péter Kempler, Csaba Lengyel, István Wittmann, Gergő A. Molnár, Gábor Sütő

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Type 2 diabetes mellitus; epidemiology; cancer; incidence; new-onset diabetes

Online: 19 February 2024 (10:20:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0190.v1

Equine Herpesvirus Type 1 ORF76 Encoding US9 as a Neurovirulence Factor in the Mouse Infection Model

Mohamed Nayel, Samy Kasem, Noriko Fukushi, Nagwan El-Habashi, Ahmed Elsify, Akram Salama, Hany Hassan, Tokuma Yanai, Kenji Ohya, Hideto Fukushi

Subject: Biology And Life Sciences, Virology Keywords: EHV-1; neurovirulence; US9; ORF76

Online: 3 September 2024 (09:42:42 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.1380.v1

The Management Approach to Health and Safety at Work in Prevention Intervention Planning

Vanessa Manni, Diego De Merich, Giuseppe Campo

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: organizative models; prevention intervention; efficacy evaluation; (worker) participation

Online: 23 October 2023 (03:35:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1768.v1

Phase Transition Analysis of the Potts-SOS Model with Spin Set {-1,0, 1} on the Cayley Tree

Hasan Akin

Subject: Computer Science And Mathematics, Mathematics Keywords: Potts-SOS model; Gibbs measure; phase transition; stability analysis

Online: 26 August 2024 (03:02:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1119.v1

Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine against XBB.1.5, BA.2.86, and JN.1 Sublineages: A Phase 2/3 Trial

Juleen Gayed, Vishva Bangad, Xia Xu, Federico Mensa, Mark Cutler, Özlem Türeci, Uǧur Şahin, Kayvon Modjarrad, Kena A. Swanson, Annaliesa S. Anderson, Alejandra Gurtman, Nicholas Kitchin

Subject: Public Health And Healthcare, Primary Health Care Keywords: BA.2.86; BNT162b2; booster; COVID-19; JN.1; Omicron; SARS-CoV-2; vaccine; variant-adapted; XBB.1.5

Online: 17 April 2024 (08:24:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0604.v1

Wolfram Syndrome 1: A Neuropsychiatric Perspective on a Rare Disease

Valerio Caruso, Accursio Raia, Luciana Rigoli

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: Wolfram syndrome 1; WFS1 gene; neuropsichiatric disorders; new findings in Wolfram syndrome 1.

Online: 8 July 2024 (10:01:16 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.0917.v1

Investigating the Interplay: Periodontal Disease and Type 1 Diabetes Mellitus - A Comprehensive Review of Clinical Studies

Stefania Vlachou, Alexandre Loume, Catherine Giannopoulou, Evangelos Papathanasiou, Alkisti Zekeridou

Subject: Public Health And Healthcare, Other Keywords: Diabetes mellitus; periodontitis; type 1 diabetes mellitus; molecular mechanisms; cellular mechanisms; oral microbiota; host immune response; oxidative stress; periodontal disease

Online: 15 April 2024 (07:26:10 CEST)

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