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Preprint ARTICLE | doi:10.20944/preprints202404.1293.v1

Mindfulness, Gut‐Brain Axis and Health Related Quality of Life: The Paradigm of IBD Patients

Efstratios Christodoulou, Tsambika Mpali, Maroula-Eleni Dimitriadou, Antonios E. Koutelidakis

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Mindfulness; gut-brain axis; health related quality of life; inflammatory bowel disease; Mediterranean diet; well-being

Online: 19 April 2024 (08:19:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0988.v1

The Antidepressant Drug Amitriptyline Affects Human SH-SY5Y Neuroblastoma Cell Proliferation and Modulates Autophagy

Annagrazia Adornetto, Maria Luisa Laganà, Andrea Satriano, Ester Licastro, Maria Tiziana Corasaniti, Giacinto Bagetta, Rossella Russo

Subject: Biology And Life Sciences, Life Sciences Keywords: amitriptyline; antidepressant; autophagy; cell proliferation; neuroblastoma; SH-SY5Y

Online: 14 May 2024 (23:32:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0476.v1

Metabolomics on Apple (Malus domestica) Cuticle—Search for Authenticity Markers

Kamila Bechynska, Jiri Sedlak, Leos Uttl, Vit Kosek, Petra Vackova, Vladimir Kocourek, Jana Hajslova

Subject: Chemistry And Materials Science, Food Chemistry Keywords: Malus domestica; apple cuticle; UHPLC-HRMS/MS; metabolomic fingerprints; classification models; markers; wax esters

Online: 8 April 2024 (03:04:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1141.v1

From Mind to Plate to Pillow: Examining the Interplay of Mental Health, Eating Disorders, and Sleep Quality

Efstratios Christodoulou, Verra Markopoulou, Antonios E. Koutelidakis

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Sleep quality; insomnia; mental health; eating disorders; well-being

Online: 17 April 2024 (12:03:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0879.v1

CoQ10 Ubiquinol: The Surfacing of Science and Role in Female and Male Fertility. A Narrative Review

E. J. Derbyshire

Subject: Biology And Life Sciences, Life Sciences Keywords: Coenzyme Q10; Conception; Infertility; Mitochondria; Oocyte; Reproduction; Sperm quality; Ubiquinol.

Online: 11 July 2024 (08:26:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0132.v1

Geography of Food Consumption Patterns between South and North China

Fangfang Song, Mi Sook Cho

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Chinese adults; north region; south region; dietary pattern; metabolic syndrome

Online: 31 October 2016 (02:51:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0137.v1

Microwave-Assisted Catalytic Synthesis of Bio-Based Copolymers from Waste Cooking Oil

Mahrzadi Noureen Shahi, Muhammad Arshad, Aman Ullah

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: waste cooking oil; phthalic anhydride; copolymerization; microwaves

Online: 17 March 2017 (07:36:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.2159.v1

Fish Consumption Frequency in the Adult Population in Poland

Katarzyna Stoś, Agnieszka Woźniak, Ewa Rychlik, Maciej Ołtarzewski

Subject: Biology And Life Sciences, Food Science And Technology Keywords: fish; consumption frequency; adults

Online: 29 August 2024 (17:03:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0161.v1

Comparing the Mechanical Properties of Rice Cells and Proto-plasts under PEG6000 Drought Stress Using Double Resonator Piezoelectric Cytometry

Yu Yan, Tiean Zhou, Yu Zhang, Zhicheng Kong, Weisong Pan, Chengfang Tan

Subject: Biology And Life Sciences, Biophysics Keywords: Double Resonator Piezoelectric Cytometry; drought stress; rice cell; protoplasts; cells generated stress; cell viscoelasticity

Online: 2 April 2024 (08:55:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0235.v1

Lactiplantibacillus plantarum Lp20 Alleviates High Fat Diet-Induced Obesity in Mice via Its Bile Salt Hydrolase Activity

Fangzhou Lu, Hui Wang, Haidong Qian, Zhengyuan Zhai, Yanling Hao

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Lactiplantibacillus plantarum; bile salt hydrolase; gene knock-out; anti-obesity

Online: 5 June 2024 (15:22:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1705.v1

MixDeR: A SNP Mixture Deconvolution Workflow for Forensic Genetic Genealogy

Rebecca Mitchell, Michelle Peck, Erin Gorden, Rebecca Just

Subject: Biology And Life Sciences, Other Keywords: mixtures; SNPs; forensic genetic genealogy (FGG); investigative genetic genealogy (IGG); Kintelligence; software

Online: 24 July 2024 (14:45:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1438.v1

From Early Adoption to Mainstream Acceptance: A Case Study on the Distribution of Electric Vehicles in Sweden (2016-2020)

Mikael Levin, Krister Sandberg, Björn Tano

Subject: Social Sciences, Decision Sciences Keywords: EV; market development; passenger car; households; leasing

Online: 25 March 2024 (08:43:22 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.1062.v1

Pectin and Pectin Oligosaccharides Obtained from Agro-Wastes as a Constituents of Soluble Dietary Fibre: Effect on the Stabili-Zation of Intestinal Microbiome and Immunity of Humans and Animals – a Review

Tomasz Marcin Hikawczuk, Patrycja Wróblewska, Anna Szuba-Trznadel, Agnieszka Rusiecka, Andrii Zinchuk, Krystyna Laszki-Szczachor

Subject: Biology And Life Sciences, Food Science And Technology Keywords: dietary fibre; pectin; pectin oligosaccharides; microbiome; GALT

Online: 18 March 2024 (15:41:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.1209.v1

Mitigating Effect of the Sea on Temperatures along Mediterra-Nean Coastal Areas: The Case of the Vine Territory of the Matera DOP – Basilicata (Italy)

Pasquale Cirigliano, Stanislao Esposito, Edmondo Di Giuseppe, Andrea Cresti

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Climate change; Viticulture; Italy-Basilicata region; Bioclimatic indices; Altitude; Temperature; Mediterranean sea

Online: 16 September 2024 (12:21:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0193.v1

Wavelet-Based Stochastic Finite Element Analysis of Steel Girders

Marcin Kamiński, Michał Guminiak, Anna Knitter-Piątkowska, Olga Kawa

Subject: Engineering, Architecture, Building And Construction Keywords: steel girders, stochastic finite element method, damage detection, discrete wavelet transform

Online: 4 June 2024 (15:26:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0546.v2

Trans-eQTLs Can Be Used to Identify Tissue-Specific Gene Regulatory Networks

Majid Nikpay

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: trans-eQTLs; tissue specificity; gene regulatory network; scale-free network

Online: 8 April 2024 (15:09:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1479.v1

Physiological Impacts of Energy Drink Consumption: A Clinical Analysis in Adolescents

Gilad Naveh, Bshara Mansour, Mahmoud Bader, Rafi Steckler, Elias Nasrallah, Hamed Hujeyrat, Faiga Magzal, Nael Elias, Omer Horovitz, Lili Nimri

Subject: Public Health And Healthcare, Other Keywords: adolescents; energy drinks; caffeine; glycemic control; insulin; glucose

Online: 21 June 2024 (07:26:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0871.v1

The Relationship between Neutrophil/Lymphocyte Ratios with Nutritional Status, Risk of Nutritional Indices, Prognostic Nutritional Indices and Morbidity in Patients with Ischemic Stroke

Naile Fevziye MISIRLIOGLU, Nedim Uzun, Gulenay Defne OZEN, Mustafa Calik, Ertugrul Altinbilek, Mehmet Necmeddin SUTASIR, Sena Baykara Sayılı, Hafize Uzun

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Ischemic stroke, prognostic nutritional index, nutritional risk index, controlling nutritional status, systemic immune inflammation index, neutrophil-lymphocyte ratio.

Online: 14 March 2024 (16:14:22 CET)

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Background: In recent years, whole blood parameters and derivatives have been used as prognostic criteria in the course of the disease in various diseases. The prognostic nutritional index (PNI), the systemic immune-inflammation index (SII), the neutrophil-lymphocyte ratio (NLR) have been adapted as an indicator of inflammation and have been widely studied to define the severity of inflammation in some diseases. The aim of this study was to evaluate the relationship between parameters such as NLR, SII, PNI, controlling nutritional status (CONUT) score, nutritional risk index (NRI) and with immunonutrition status and disease activity in patients with ischemic stroke of small vessel, large vessel and other etiologies. Methods: We retrospectively evaluated the records of 1454 consecutive ischemic stroke patients hospitalized in the emergency department of Gaziosmanpasa Education and Research Hospital from 2019 to 2023. Results: Of the 1350 SVO patients included in the study, 58.8% had small vessel, 29.3% had large vessel and 11.9% had other etiologies. There was a significant difference between the 3 etiology groups for PNI and CONUT. The median PNI was 47.03 (41.33-52.85) in the other etiology group, 35.29 (33.69-37.25) in the small vessel group, and 34.11 (30.23-36.87) in the large vessel group. The CONUT median was 5(5-6) in the small vessel group, 5(4-6) in the large vessel group and 4(4-4) in the other etiology group. In addition, CONUT and PNI were also found to be independent risk factors for death. A negative significant correlation was observed between PNI and NLR (r:-0.692), SII (r:-0.591), CONUT (r:-0.685). Significant correlations were observed between CONUT and NLR (r:0.402), SII (r:0.312). Conclusion: PNI and SII were significantly associated with disease activity. PNI, CONUT and NRI as a more accurate prognostic indicator of nutritional status in patients with ischemic stroke of small vessel, large vessel and other etiologies. NLR and SII may be important predictive markers in the course and prognosis of stroke.

Preprint REVIEW | doi:10.20944/preprints202402.1104.v1

Exploring the Gut-Mitochondrial Axis: the p66Shc Adapter Protein and Its Implications for Metabolic Disorders

Ana Clara Da C. Pinaffi-Langley, Elizabeth Melia, Franklin A Hays

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: p66Shc; adaptor protein; oxidative stress; gut microbiota; inflammation; mitochondrial dysfunction

Online: 20 February 2024 (07:10:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.2046.v1

Seismic Damage Assessment of Existing Planar Steel X or V-Braced Frames Using the Hybrid "M and P" Technique

Triantafyllos Makarios, Athanasios Bakalis, Evangelos Efthymiou

Subject: Engineering, Civil Engineering Keywords: Damage identification; Steel Braced Frames; Concentric X or V-bracing; Stepping Eigenfrequencies; Capacity Curve; Target Displacement

Online: 29 August 2024 (02:52:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1435.v1

A New Approach for Understanding International Hospital Bed Numbers and Application to Local Area Bed Demand and Capacity Planning

Rodney P Jones

Subject: Public Health And Healthcare, Health Policy And Services Keywords: hospital beds; bed modeling; bed occupancy; age-standardized mortality rate (ASMR); crude mortality rate; population deprivation; births; pediatric care; adult care; social care; elderly care; critical care; sex; age; Northern Territory; Tasmania; England

Online: 22 May 2024 (11:09:43 CEST)

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A new model for international bed numbers is applied to local area populations for English Clinical Commissioning Groups (CCGs) where the Age Standardized Mortality Rate (ASMR) is used as a measure of population health and hence for total occupied hospital bed demand (elective plus emergency admission types, including acute, rehabilitation, mental health, and maternity), rather than simple bed availability. A 100-unit increase in ASMR (European Standard population) leads to a 15.3 – 30.7 (feasible range) unit increase in occupied beds per 1,000 deaths. ASMR shows why the Australian states of the Northern Territory and Tasmania have an intrinsic higher bed demand than the other states – although in both cases the bed planning methodologies failed to indicate this need and both states show a large bed deficit. Due to the high volatility in bed demand the average bed demand for 2019 was determined by a linear trend using data for 2014/15 to 2019/20 — as the pre-COVID-19 baseline. The slope of the relationship between occupied beds per 1,000 deaths and deaths per 1,000 population shows a power law function. As is to be expected there is scatter around the trend line which will partly arise from uncertainty in the expected occupied beds in 2019, fluctuations in both ASMR and deaths per 1,000 population from one year to another, changes in the number of persons on the elective, outpatient and diagnostic waiting lists, and local area variation in births and consequently upon maternity, neonatal and pediatric bed demand. Additional variation in bed demand will arise from differences in the level of funding for social care, especially elderly care, and to a lesser extent upon patients using private health care, and charitable hospices for palliative care. However, after including the change in bed demand arising from ASMR the model is sufficiently accurate to identify gross differences in bed demand as a prelude to further investigation. The model requires further extension to cover specialty-level demand, and perhaps segregation between elective and emergency types of inpatient demand. A method for benchmarking the whole hospital’s average bed occupancy is given which enables them to run at optimum efficiency and safety. Using this method English hospitals can be shown to operate at highly disruptive and unsafe levels of bed occupancy leading to deleterious ‘turn-away’. Turn-away implies bed unavailability for the next arriving patient. The problems associated with crafting effective bed planning are illustrated using the English NHS as an example.

Preprint ARTICLE | doi:10.20944/preprints202407.1332.v1

Fault-Tolerant Optimal Consensus Control for Heterogeneous Multi-agent System

Yandong Li, Yongan Liu, Ling Zhu, Zehua Zhang

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: uncrewed aerial vehicle; uncrewed ground vehicle; heterogeneous multi-agent system; actuator failures; consensus; Lyapunov stability theory; optimal method

Online: 16 July 2024 (12:28:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.1916.v1

The Evolution of Meteorological Satellite Cloud Detection Methodologies

Filomena Romano, Domenico Cimini, Francesco Di Paola, Donatello Gallucci, Salvatore Larosa, Saverio Teodosio Nilo, Elisabetta Ricciardelli, Barbara D Iisager, Keith Hutchison

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: cloud detection; meteorological satellite; remote sensing

Online: 29 May 2024 (07:22:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0834.v1

BBPE-AE: A Byte Pair Encoding-Based Auto Encoder for Password Guessing

Samane Ghafari, Leila Safari, Mohsen Afsharchi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Password Guessing; Cybersecurity; Password Strength Assessment; Autoencoder Network; Long Short-Term Memory (LSTM) Networks; Byte-level Byte Pair Encoding

Online: 11 September 2024 (10:49:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1259.v1

Application of the Discrete Wavelet Transform to Damage Detection in a Guy Cable of Guyed Antenna Mast

Anna Knitter-Piątkowska, Maciej Przychodzki, Michał Guminiak

Subject: Engineering, Civil Engineering Keywords: truss steel mast; guy ropes; finite element method; damage detection; discrete wavelet transform

Online: 21 March 2024 (08:20:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1438.v1

The Impacts of Frozen Material-Other-Than-Grapes (MOG) on Aroma Compounds of Cabernet Franc and Cabernet Sauvignon

YIBIN LAN, Xiaoyu Xu, Jiaming Wang, Emily Aubie, Marnie Crombleholme, Andrew Reynolds

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Monoterpenes; norisoprenoids; esters; higher alcohols; sensory analysis; mechanical harvesting

Online: 20 June 2024 (13:03:43 CEST)

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An undesirable sensory attribute (“floral taint”) has been recently detected in red wines in some winegrowing jurisdictions in North America (e.g. Ontario, British Columbia, Washington), caused by introduction of frost-killed leaves and petioles [materials-other-than-grapes (MOG)] during mechanical harvest and winemaking. It was hypothesized that terpenes, norisoprenoids, and higher alcohols would be the main responsible compounds. Objectives were to investigate causative volatile compounds for floral taint, and explore threshold concentrations for this problem. Commercial wines displaying varying intensities of floral taints were subjected to GC-MS and sensory analysis. Several odor-active compounds were higher in floral-tainted wines, including terpenes (geraniol, citronellol, cis- and trans-rose oxide), norisoprenoids (β-damascenone, β-ionone), five ethyl esters, and three alcohols. Thereafter, fermentations of Cabernet franc (CF) and Cabernet Sauvignon (CS) (2016, 2017) were conducted. MOG treatments were (wt/wt): 0, 0.5%, 1%, 2% and 5% petioles, and 0, 0.25%, 0.5%, 1%, and 2% leaf blades. Terpenes (linalool, geraniol, nerol, nerolidol, citronellol, citral, cis- and trans-rose oxides, eugenol, myrcene), norisoprenoids (α- and β-ionone), and others (e.g. hexanol, octanol, methyl and ethyl salicylate) increased linearly/quadratically with increasing MOG levels in both cultivars. Principal components analysis separated MOG treatments from the controls with 5% petioles and 2% leaves as extremes. Increasing MOG levels in CF wines increased floral aroma intensity, and were primarily associated with terpenes, higher alcohols, and salicylates. Increased leaf levels in CF were associated with higher vegetal and earthy attributes. Increased petioles in CS were not correlated with floral aromas, but increased leaves increased floral, vegetal and herbaceous attributes. Overall, petioles contributed more to floral taint than leaves through increased terpenes and salicylates (floral notes), while leaves contributed norisoprenoids and C6 alcohols (green notes).

Preprint ARTICLE | doi:10.20944/preprints202406.0123.v1

Manual Dexterity and Hand Grip Strength Modifications After Application of Transcranial Static Magnetic Field Stimulation (tSMS) Over the Primary Motor Cortex (M1) in Healthy Subjects: A Triple-Blind, Randomized Clinical Trial

Víctor Navarro-López, María Carratalá-Tejada, Antonio Oliviero, Diego Fernández Vázquez, Manuel Del-Valle-Gratacós, Samuel Jiménez Jiménez, Francisco Molina-Rueda

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Manual Dexterity; Motor Cortex; Non-Invasive Brain Stimulation (NIBS); Transcranial Static Magnetic Field Stimulation (tSMS)

Online: 4 June 2024 (08:20:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1307.v1

Characterization of Nutritional Potential of Amaranthus sp. Grain Production

Alexandru Mătieș, Cornel Negrușier, Oana Roșca Mare, Olimpia Smaranda Mintaș, Gabriela Zanc (Săvan), Antonia Cristina Maria Odagiu, Luiza Andronie, Ioan Păcurar

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: morpho-productive traits; correlations; food; seed

Online: 23 February 2024 (10:33:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0021.v1

Solvency II Calibrations: Where Curiosity Meets Spuriosity

Stefan Mittnik

Subject: Business, Economics And Management, Finance Keywords: Solvency capital requirements capital, standard formula, near unit root, spurious correlation, VaR—implied correlations, tail dependence

Online: 12 July 2016 (09:38:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1818.v1

Development and Evaluation of Bioconverted Milk with Antimicrobial effect against Oral Pathogens and α-Glucosidase Inhibitory Activity

Yewon Lee, Yohan Yoon, Kyoung-hee Choi

Subject: Biology And Life Sciences, Food Science And Technology Keywords: bioconverted milk; probiotics; Artemisia herba-alba; oral pathogens; α-glucosidase

Online: 28 May 2024 (05:39:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1264.v1

Long-Range Imaging of Alpha Emitters Using Radioluminescence in Open Environments: Daytime and Nighttime Applications

Lingteng Kong, Thomas Bligh Scott, John Charles Clifford Day, David Andrew Megson-Smith

Subject: Physical Sciences, Radiation And Radiography Keywords: Alpha Radiation Detection; Radio-luminescnece; Alpha Fluorescence; Long-Distance Monitoring; Solar Blind detector

Online: 17 July 2024 (04:49:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1488.v1

Residential Greenness, Lifestyle and Vitamin D: A Longitudinal Cohort of South Asian Origin and Caucasian Ethnicity Women Living in the South of the UK

Keila Valente de Souza Santana, Helena Ribeiro, Andrea Darling, Israel Henrique Ribeiro Rios, Susan Lanham-New

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Vitamin D, Ultraviolet radiation, Residential greenness, Ethnicity, Parathyroid hormone.

Online: 26 February 2024 (15:50:51 CET)

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Preprint COMMENT | doi:10.20944/preprints201608.0166.v1

Regional Inequality in Underdeveloped Areas: A Case Study of Guizhou Province in China

Wei Sun, Xiaona Lin, Yutian Liang, Lu Li

Subject: Social Sciences, Geography, Planning And Development Keywords: Regional inequality; Multilevel regression; Markov chain; Guizhou Province

Online: 17 August 2016 (12:58:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1381.v1

Results on Cumulative Entropic Properties of Consecutive Systems

Mashael A. Alshehri, Mohamed Kayid

Subject: Engineering, Control And Systems Engineering Keywords: Consecutive k-out-of-n:F systems; Cumulative entropy; Shannon entropy; Stochas- tic orders; Real data

Online: 20 August 2024 (03:40:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1745.v1

Early Mediterranean-Based Nutritional Intervention Reduces the Rate of Gestational Diabetes Mellitus in Overweight and Obese Pregnant Women: A Post-Hoc Analysis of the San Carlos Gestational Prevention Study

Rocio Martin-O´Connor, Ana M. Ramos-Leví, Verónica Melero, María Arnoriaga-Rodríguez, Ana Barabash, Johanna Valerio, Laura Del Valle, María Paz De Miguel Novoa, Angel Díiaz, Cristina Familiar, Inmaculada Moraga, Alejandra Durán, Martín Cuesta, Maria Jose Torrejón, Mercedes Martinez-Novillo, Clara Marcuello, Mario Pazos, Miguel Ángel Rubio-Herrera, Pilar Matía-Martín, Alfonso Luis Calle-Pascual

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: obesity; overweight; metabolic syndrome; fasting blood glucose; mediterranean diet

Online: 27 May 2024 (13:30:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0202.v2

Remote Sensing and Data Mining Techniques for Assessing the Urban Fabric Vulnerability to Heat Waves and UHI

Flavio Borfecchia, Vittorio Rosato, Emanuela Caiaffa, Maurizio Pollino, Luigi De Cecco, Luigi La Porta, Simone Ombuen, Lorenzo Barbieri, Federica Benelli, Flavio Camerata, Valeria Pellegrini, Andrea Filpa

Subject: Environmental And Earth Sciences, Environmental Science Keywords: HR satellite remote sensing; urban fabric vulnerability; UHI & heat waves; landsat & MODIS sensors; LST & urban heating; segmentation & objects classification; data mining; feature extraction & selection; stepwise regression & model calibration

Online: 26 October 2021 (13:11:23 CEST)

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Densely urbanized areas, with a low percentage of green vegetation, are highly exposed to Heat Waves (HW) which nowadays are increasing in terms of frequency and intensity also in the middle-latitude regions, due to ongoing Climate Change (CC). Their negative effects may combine with those of the UHI (Urban Heat Island), a local phenomenon where air temperatures in the compact built up cores of towns increase more than those in the surrounding rural areas, with significant impact on the quality of urban environment, on citizens health and energy consumption and transport, as it has occurred in the summer of 2003 on France and Italian central-northern areas. In this context this work aims at designing and developing a methodology based on aero-spatial remote sensing (EO) at medium-high resolution and most recent GIS techniques, for the extensive characterization of the urban fabric response to these climatic impacts related to the temperature within the general framework of supporting local and national strategies and policies of adaptation to CC. Due to its extension and variety of built-up typologies, the municipality of Rome was selected as test area for the methodology development and validation. First of all, we started by operating through photointerpretation of cartography at detailed scale (CTR 1: 5000) on a reference area consisting of a transect of about 5x20 km, extending from the downtown to the suburbs and including all the built-up classes of interest. The reference built-up vulnerability classes found inside the transect were then exploited as training areas to classify the entire territory of Rome municipality. To this end, the satellite EO HR (High Resolution) multispectral data, provided by the Landsat sensors were used within a on purpose developed "supervised" classification procedure, based on data mining and “object-classification” techniques. The classification results were then exploited for implementing a calibration method, based on a typical UHI temperature distribution, derived from MODIS satellite sensor LST (Land Surface Temperature) data of the summer 2003, to obtain an analytical expression of the vulnerability model, previously introduced on a semi-empirical basis.

Preprint ARTICLE | doi:10.20944/preprints202408.2264.v1

Dietary Omega-3 PUFA Intake in Patients with Chronic Kidney Disease: The Association with Vitamin D Deficiency, Intima-Media Thickness and Blood Pressure

Danijela Ristic-Medic, Marija Takic, Biljana Pokimica, Brankica Terzic, Milica Kojadinovic, Toplica Lepic, Slavica Radjen, Vesna Vucic

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: omega-3; carotid intima-media thickness; chronic kidney disease; cardiovascular risk; hemodialysis

Online: 30 August 2024 (15:32:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1901.v1

Nutritional, Phytochemical, and Functional Properties of Four Edible Orchid Species from Malawi

Felix Daire Kumwenda, Jimmy Sumani, Wilson Jere, Kumbukani Kafwirangachi Nyirenda, Jonas Mwatseteza

Subject: Biology And Life Sciences, Food Science And Technology Keywords: edible orchids; Disa; Satyrium; phytochemicals; proximate; total phenolics; functional properties

Online: 27 June 2024 (02:46:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0064.v1

A Comprehensive Analysis of Organic Food: Evaluating Nutritional Value and Impact on Human Health

Azizur Rahman, Parnian Baharlouei, Eleanor Hui Yan Koh, Gabby Pirvu, Rameesha Rehmani, Mateo Arcos, Simron Puri

Subject: Biology And Life Sciences, Food Science And Technology Keywords: organic foods; food safety; obesity; cancer; biodiversity; climate change; organic farming

Online: 2 October 2023 (12:02:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0219.v1

A Model to Estimate the Cost-Effectiveness of Water Pollution Management Strategies in Developing Countries: The Cocody Bay Case, Côte d’Ivoire

Vassiki Sanogo

Subject: Business, Economics And Management, Economics Keywords: pollution; cost-effectiveness analysis; Cocody; environmental policies; environmental constraints

Online: 27 August 2016 (11:01:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.0559.v1

Advancements in CM Drying Technology: A Comprehensive Review of Methods, Chemical Composition, and Nutritional Preservation

Ayaulym Rakhmatulina, Fatima Dikhanbayeva, Dinara Abaevna Tlevlesova, Jelena Zagorska, Nurbek Aralbayev, Kristine Majore, Aidana Essenova

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Camel Milk; freeze-drying; powder; spray drying; Reduction of process duration

Online: 8 April 2024 (12:30:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.2243.v1

GC-MS analysis, Elemental and Nutritional Composition and Biological Investigation of Medicinally Valued Fingerhuthia africana Lehm.

Hamid Ullah, Muhammad Adil, Faten Zubair Filimban

Subject: Biology And Life Sciences, Plant Sciences Keywords: GC-MS; proximate analysis; genotoxic activity; DPPH; antidiarrheal activity

Online: 29 December 2023 (11:29:14 CET)

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Fingerhuthia africana Lehm belongs to family Poaceae, is an erect perennial grass used traditionally to cure different diseases. The current study was carried out to find the bioactive compounds by GC-MS, elemental analysis through atomic absorption spectrophotometry, proximate analysis by AOAC, genotoxic activity through comet assay, antioxidant activity through DPPH and antidiarrheal activity through castor oil induce diarrhea followed by charcoal meal on mice model. GC-MS chromatogram represents different compounds detected in the crude extract. Major pharmacological bioactive compounds are 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-; 4-Methyl itaconate; .alpha.-Terpineol; 1,2,3-Propanetriol, 1-acetate; Benzofuran, 2,3-dihydro-; Caryophyllene oxide; Hinesol; n-Hexadecanoic acid; 9,12-Octadecadienoic acid (Z,Z)-, methyl ester; Hexadecanoic acid and methyl ester. Elemental analysis of stem, leaves and roots of the plant show the presence of (macro and micro) nutrients such as Ca, Mg, K, Na, Cu, Pb, Zn, Mn, Fe, Cd and Co were absent in all parts. Proximate analysis of different parts revealed the presence of moisture contents (8.57%), ash (9.77%), fats contents (5.96%), fibers contents (45.03%), protein (3.62%), carbohydrates (39.71%) and Gross energy (Kcal/100g) (220.10). The ethanolic extract show dose-dependent genoprotective potential (127.38 ± 1.16), (83.28 ± 0.65), and (44.08 ± 1.40) at 50, 75, and 100 mg/100 ml, respectively, as compared to the methanolic extract which show genotoxic activity (85.13 ± 1.23) at high dose. After 90 minutes at a concentration of 300 (g/ml), methanolic extract demonstrated the greatest antioxidant potential (79.5%), followed by aqueous extract (76.5%). The methanolic extract of F. africana demonstrated antidiarrheal efficacy, with the maximum inhibition of charcoal movement (83.78%) occurring at a dosage of 300 mg/kg, followed by doses of 200 and 100 mg/kg, 73.26% and 59.56%, respectively. The current research highlights that the plant contains a substantial quantity of micro and macro nutrients, possesses high nutritional value, and exhibits pharmacological activities. These properties render the plant suitable for developing remedies to treat various therapeutic diseases.

Preprint REVIEW | doi:10.20944/preprints202409.0710.v1

Nutritional Values of Wheat and the Roles and Functions of Its Compositions in Health

Md. Zaherul Islam, Mohammad Nur Alam, Mohammad Mokhlesur Rahman, Mohammad Zaherul Islam, Aminur Rahman

Subject: Biology And Life Sciences, Plant Sciences Keywords: Gluten proteins; Nutritional quality; Vitamins and minerals; Wheat grain

Online: 9 September 2024 (16:45:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0488.v1

Fractianal Calculus for Non-discrete Signed Measures

Vassili N. Kolokoltsov, Elina Shishkina

Subject: Physical Sciences, Mathematical Physics Keywords: general fractional calculus; fractional integral with signed measure; fractional power of first order partial differential operator; quantum mechanic; fractional Poisson brackets; fractional Heisenberg brackets

Online: 7 August 2024 (17:53:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1363.v1

Application of the Transmutation Operator Method to the Solution of an Initial Boundary Value Problem for the Equation of Multidimensional Free Transverse Vibration of a Thin Elastic Plate Containing the Bessel Operator

Shakhobiddin Karimov, Yorkinoy Tulasheva

Subject: Computer Science And Mathematics, Mathematics Keywords: fourth-order equation; plate vibration equation; Bessel operator; transmutation operator; Erdélyi–Kober operator

Online: 19 June 2024 (15:02:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0069.v1

Comparison of Pixel- and Object-Based Approaches in Phenology-Based Rubber Plantation Mapping in Fragmented Landscapes

Deli Zhai, Jinwei Dong, Georg Cadisch, Mingcheng Wang, Weili Kou, Jianchu Xu, Xiangming Xiao

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Rubber (Hevea brasiliensis) plantation; phenology; Xishuangbanna; Landsat; object-based approach; pixel-based approach

Online: 6 August 2016 (11:54:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0147.v1

A Method to Classify Texts Based on Sentiment Analysis and Machine Learning

Claudia Corona López, Jesus Urias Piña, Rafael Lahoz-Beltra

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Sentiment analysis; text classification; machine learning

Online: 5 March 2024 (05:10:29 CET)

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Preprint REVIEW | doi:10.20944/preprints202308.1452.v1

Application of bioelectrical impedance analysis in nutritional management of patients with chronic kidney disease

Yanchao Guo, Meng Zhang, Ting Ye, Zhixiang Wang, Ying Yao

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: body composition; bioelectrical impedance analysis; chronic kidney disease; nutrition

Online: 21 August 2023 (09:57:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1592.v1

New Physically-Based Mathematical Model and Experiments for a Recently Invented Solar Pot

Márton Rátkai, Gábor Géczi, Richárd Kicsiny, László Székely

Subject: Engineering, Mechanical Engineering Keywords: solar cooking; solar pot; mathematical modelling; simulation results; measurements

Online: 24 June 2024 (08:16:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1658.v1

Body Composition and Nutritional Status in a Group of University Students

Stela-Gabriela Jelea, Oana-Corina Jelea, Marian Jelea

Subject: Public Health And Healthcare, Other Keywords: students; body composition; nutritional status, constitutional index

Online: 28 February 2024 (15:30:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0066.v1

Nutritional Assessment, Body Composition and Low Energy Availability in Sport Climbing Athletes of Different Genders and Categories: A Cross-Sectional Study

Agustin Mora-Fernandez, Andrea Argüello-Arbe, Andrea Tojeiro-Iglesias, Jose Antonio Latorre, Javier Conde-Pipó, Miguel Mariscal-Arcas

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: nutrition assessment; sport climbing; bouldering; rock climbing; low energy availability; dietary intake; relative energy deficiency in sport

Online: 2 August 2024 (03:58:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0722.v1

Nutritional and Phytochemical Profiles of Wild Adlay (Coix lacryma-jobi L.) Accessions by GCFID, FTIR, and Spectrophotometer

Rauf Ahmad, Abdul Mueed, Muhammad Liaquat, Shehla Sammi, Muhammad Jahangir, Amer Mumtaz, Imran Khan, Khalid Mashay Al-Anazi, Mohammad Abul Farah, Akhtar Ali

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Adlay; functional groups; physicochemical; triglyceride; GCFID; FTIR

Online: 13 February 2024 (07:31:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0860.v1

Development and Pilot Study of myfood24 West Africa — an Online Tool for Dietary Assessment in Nigeria

Chinwe Adaugo Uzokwe, Chiaka Charles Nkwoala, Bassey Ebenso, Sarah Beer, Grace Williams, Gideon Iheme, Chihurumnanya Opara, Rasaki Sanusi, Henrietta Nkechi Ene-Obong, Janet E Cade

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Food composition tables; energy intake; nutrition assessment; nutrition app; usability study; digital tool; diet monitoring

Online: 11 September 2024 (07:32:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0966.v1

Genetic Variability and Interrelationships of Grain Quality, Cooking Quality and Nutritional Quality Traits in Cowpea: Implication for Cowpea Improvement

Michael M. Chipeta, Esnart Yohane, Jessica Kampanje-Phiri, John Kafwambira

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Consumer-preferred traits; cowpea, genetic variability; interrelationships; quality traits

Online: 19 February 2024 (03:32:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0869.v1

Nutritional Trends in Cystic Fibrosis: Insights from the Italian Cystic Fibrosis Patient Registry

Donatello Salvatore, Rita Padoan, Annalisa Amato, Marco Salvatore, Giuseppe Campagna

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: cystic fibrosis, nutrition, obesity

Online: 15 April 2024 (08:07:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1109.v1

Microbiological, Antioxidant, Nutritional Properties, and Health Safety of Juice from Organic and Conventional Vitis vinifera L. Farming

Ireneusz Ochmian, Sebastian Wojciech Przemieniecki, Magdalena Błaszak, Magdalena Twarużek, Sabina Lachowicz-Wiśniewska

Subject: Biology And Life Sciences, Food Science And Technology Keywords: grapes; organic farming; microbiome; environmental protection; pesticide residues; mycotoxins; polyphenols

Online: 17 June 2024 (07:51:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1536.v1

The Effectiveness of Nutritional Interventions Implemented Through Lady Health Workers on the Reduction of Stunting in Children under 5 in Pakistan; The Difference‐in‐Difference Analysis

Khizar Ashraf, Tanvir M. Huda, Javeria Ikram, Shabina Ariff, Muhammad Sajid, Gul Nawaz Khan, Muhammad Umer, Imran Ahmed, Michael John Dibley, Sajid Bashir Soofi

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: nutrition; Pakistan; Stunting prevention; Lipid based nutrient supplements; programmatic review

Online: 23 April 2024 (17:51:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0734.v1

Validation of OLCI Sentinel-3 water products in the Baltic Sea and evaluating the effect of System Vicarious Calibration (SVC)

Sean O’Kane, Tim McCarthy, Rowan Fealy, Susanne Kratzer

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: OLCI; Sentinel-3; C2RCC; System Vicarious Calibration (SVC); Baltic Sea; Coloured Dissolved Organic Matter (CDOM); Chlorophyll-a; Total Suspended Matter (TSM)

Online: 12 August 2024 (11:25:32 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202406.0396.v1

Copper Supplementation in Young Wistar Rats

Klaudia Kitala–Tańska, Anetta Hanć, Jerzy Juśkiewicz, Michał Majewski

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: aortic rings; copper; vascular studies

Online: 7 June 2024 (02:51:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints201612.0048.v1

A Review on Phytochemistry and Pharmacology of Cortex Periplocae

Yang Li, Jin Li, Kun Zhou, Jun He, Jun Cao, Ming-Rui An, Yan-Xu Chang

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Cortex Periplocae; traditional Chinese medicines; periplocin; phytochemistry; biological activities

Online: 8 December 2016 (10:24:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202405.0202.v1

Nutritional Factors and Survival in a Cohort of Patients with Oral Cancer

Paolo Buscemi, Cristiana Randazzo, Carola Buscemi, Anna Maria Barile, Elena Finamore, Roberta Caruso, Piero Colombrita, Martina Lombardo, Serena Cangemi, Giulia Zucchi, Adriana Cordova, Antonio Lo Casto, Silvio Buscemi

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Oral cancer; malnutrition; artificial nutrition; bioimpedance analysis

Online: 6 May 2024 (08:46:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0523.v1

A Step Forward Understanding Directional Limitations in Markerless Smartphone-based Gait Analysis

Pavol Martiš, Zuzana Košutzká, Andreas Kranzl

Subject: Engineering, Bioengineering Keywords: OpenCap; Markerless Gait Analysis; Directional Bias in Motion Analysis; Gait kinematics; Smartphone-based Motion Capture; Timed Up and Go (TUG) Test

Online: 8 March 2024 (11:04:15 CET)

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Preprint REVIEW | doi:10.20944/preprints202304.0859.v1

Nutritional Aspects of Iron in Health and Disease

Edouard Charlebois, Kostas Pantopoulos

Subject: Medicine And Pharmacology, Other Keywords: Iron deficiency; iron overload; anemia; heme; metabolic syndrome; cardiovascular disease; cancer; microbiome

Online: 24 April 2023 (12:48:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0316.v1

Eating Behavior and Nutritional Status in Spanish Schoolchildren

Andrea Calderón García, Ana Maria Alaminos Torres, Roberto Pedrero Tomé, Consuelo Prado Martínez, Jesús Román Martínez Álvarez, Antonio Villarino Marín, Maria Dolores Marrodán Serrano

Subject: Biology And Life Sciences, Food Science And Technology Keywords: appetite; saciety response; eating behavior; pediatric obesity; anthropometry

Online: 21 October 2022 (03:27:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202108.0097.v1

Goat Milk: Compositional, Technological, Nutritional, and Therapeutic Aspects

Ahmed R. A. Hammam, Saleh M. Salman, Mohamed S. Elfaruk, Khalid A. Alsaleem

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Goat population; Goat milk; Milk production; Milk composition; Goat cheese; Therapeutic properties

Online: 3 August 2021 (15:57:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1110.v1

Coffee Blending and Grinding: Nutritional, Sensorial and Sustainable Aspects

Gabriel Henrique Horta de Oliveira, Ana Paula Lelis Rodrigues de Oliveira

Subject: Engineering, Other Keywords: sustainability; coffee production; quality.

Online: 18 October 2023 (18:27:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1799.v1

Suboptimal Nutritional Status of School-Age Children in Addis Ababa: Evidence from the Analysis of Sociodemographic, Environmental, and Behavioral Factors

Yimer Mihretie Mihretie, Abebe Ayelign, Tadesse Alemu Zerfu

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: ; Addis Ababa; dietary factors; nutritional status; school-age children

Online: 25 January 2024 (09:53:52 CET)

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Preprint REVIEW | doi:10.20944/preprints201710.0195.v1

Impact of Optimized Protein in Infant Formula on the Metabolic and Nutritional Health in Infants: Systematic Review with Meta-Analysis

Pedro Gutierrez-Castrellon, Javier Luna-Carrasco, Anahi Anzo-Osorio, Luisa Diaz Garcia, Salvador Villalpando-carrion, Gabriel López-Velázquez, Carlos Jiménez-Gutiérrez

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Optimized protein in formula, infants, obesity risk reduction

Online: 31 October 2017 (15:29:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1219.v1

Usefulness of Perioperative Nutritional Therapy with the Glutamine/Arginine/Calcium β-Hydroxy-β-Methylbutyrate Product in Esophageal Cancer Surgery: A Single-Center Retrospective Study

Koichi Okamoto, Hiroyuki Takamura, Taigo Nagayama, Yuta Sannomiya, Akifumi Hashimoto, Hisashi Nishiki, Daisuke Kaida, Takashi Miyata, Toshikatsu Tsuji, Hideto Fujita, Shinichi Kinami, Itasu Ninomiya, Noriyuki Inaki

Subject: Medicine And Pharmacology, Surgery Keywords: esophageal cancer; minimally invasive esophagectomy; complication; sarcopenia

Online: 18 June 2024 (11:29:15 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.2111.v1

Relevance of Diet in Schizophrenia: Focusing on Prenatal Nutritional Deficiency, Obesity, Oxidative Stress and Inflammation

Amalia Vasile, Viorica Rarinca, Vasile Burlui, Gabriela Halitchi, Alin Ciobică, Ana-Maria Singeap, Romeo Dobrin, Ecaterina Burlui, Anca Trifan

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Schizophrenia; Diet; Nutrients; Obesity; Oxidative Stress; Inflammation; Antioxidants

Online: 26 July 2024 (11:30:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0896.v1

Nutritional Screening and Assessment in Mexican Outpatient Cancer Patients

Gabino Cervantes-Guevara, Karla Veronica Chavez, Blanca Ernestina Vazquez-Lopez, Zayda Vanessa Herrera-Ponce, Lisset Citlali Magaña-de la Vega, Clotilde Fuentes-Orozco, Alejandro Gonzalez-Ojeda, Diana Mercedes Hernandez-Corona, Tonatiuh Gonzalez-Heredia, Miriam Méndez-del Villar, Fernada Isadora Corona-Meraz, Milton Omar Guzman-Ornelas, Linda Paola Gomez-Cabral, Jose Alberto Gonzalez-Duarte, Fernanda Monserrat Rendon-Serrano, Mariana Chavez-Tostado

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: malnutrition; cancer; GLIM criteria; PG-SGA; NRS-200; MUST; MST; nutriscore

Online: 12 September 2024 (10:57:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.1349.v1

Exploring the Nutritional Potential and Functionality of Hemp and Rapeseed Proteins: A Review on Unveiling Anti-nutritional Factors, Bioactive Compounds, and Functional Attributes

Marina Axentii, Georgiana Gabriela Codină

Subject: Biology And Life Sciences, Food Science And Technology Keywords: hemp; rapeseed; protein; functionality; anti-nutritional factors; bioactive compounds; food applications; digestibility; innovative products

Online: 24 February 2024 (08:53:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0023.v1

A Novel Method for Multiple Mycotoxins Analysis in Feedstuffs by Flow-Through Cartridge Purification and Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

Rui-guo Wang, Xiao-ou Su, Zhang Wei, Pei-long Wang, Zhi-qi Zhang, Ai-bo Wu, Chuan-min Cheng, Yan Xue, Yu Li

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: UPLC-MS/MS; mycotoxins; feedstuffs; flow-through; multiple analysis

Online: 5 December 2016 (09:40:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.1904.v1

Key Drivers of Consumption, Conceptual, Sensory, and Emotional Profiling of Cheeses Based on Origin and Consumer Familiarity: A Case Study of Local and Imported Cheeses in Greece

Malamatenia Panagiotou, Efstathios Kaloudis, Danai Ioanna Koukoumaki, Vasiliki Bountziouka, Evangelia Giannakou, Margarita Pandi, Konstantinos Gkatzionis

Subject: Biology And Life Sciences, Food Science And Technology Keywords: cheese; social media; Flash Profile; focus groups; protected designation of origin

Online: 24 July 2024 (08:06:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0768.v1

Appropriate Soil Fertilization or Drone-based Foliar Zn Spraying Can Simultaneously Improve Yield and Micronutrient (Particularly for Zn) Nutritional Quality of Wheat Grains

Xue Gao, Qiang Zhao, Nuo Yuan, Xiaojing Li, Bin Zhang, Yinghua Zhu, Lingan Kong, Zhaohui Wang, Haiyong Xia

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: zinc; micronutrient; macronutrient; agronomic biofortification; compound fertilizer; drone technology; foliar spraying

Online: 12 August 2024 (09:46:21 CEST)

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To better understand effects of agronomic practices on yield-nutrition relationships in wheat (Triticum aestivum L.) grains for Zn biofortification while improving yields simultaneously, effects of different soil fertilization and different drone-based foliar spraying treatments were investigated. The mixture of Zn or increasing N but simultaneously reducing P in compound fertilizers were all practical to increase grain yields and Zn concentrations in calcareous soils tested. However, the overall effects are limited, with a maximal yield increase by only 7.0% and a maximal increase of the grain Zn density from 19.4 to 27.0 mg/kg, which is far below the target biofortification value of 40-50 mg/kg. Unfortunately, there was a negative side effect, which decreased Fe and Mn concentrations and the Fe bioavailability. Notably, grain yields and Zn concentrations were significantly increased by drone-based foliar Zn sprayings from 7.5 to 8.6~8.8 t/ha by 12.0-17.3% and from 33.5 to 41.9~43.6 mg/kg by 25.1~30.1%, respectively, indicating a double-win in yield and nutrition. A spraying of ZnSO4·7H2O increased grain Zn concentrations and accumulation more so than ZnO, indicating the importance of chemical Zn forms in determining the effectiveness of foliar spraying. Moreover, foliar Zn sprayings simultaneously increased grain concentrations and accumulation of Fe, Mn and Cu, demonstrating multiple benefits. There were positive correlations between Zn and Fe, Mn or Cu, indicating synergistic but not antagonistic interactions. Compared to micronutrients, concentrations of grain macro- and medium nutrients (N, P, K, Ca, Mg) were less affected. Thus, a double-win in grain yields and micronutrient (particulaly for Zn) nutrition could be effectively achieved through appropriate soil fertilization and foliar Zn spraying. These results provide a better understanding of the yield-nutrition relationship among wheat grain yields, Zn and other nutrient elements for a better integrated manipulation to achieve a win-win situation in yield and nutrition.

Preprint ARTICLE | doi:10.20944/preprints202403.0953.v1

Fruit Quality Traits and Nutritional Value of Tomato F1 Hybrids Derived from Traditional Varieties

Alicia Sánchez Sánchez, Virginia Hernández, Elena Sánchez, Elia Molina, Nuria Lopez, Adrian Rodríguez-Burruezo, José Fenoll, Pilar Flores, Pilar Hellín

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Landraces, tomato breeding, fruit quality, evaluation index

Online: 18 March 2024 (09:05:46 CET)

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Preprint REVIEW | doi:10.20944/preprints202407.1988.v1

Dual Antibiotic Approach: Synthesis and Antibacterial Activity of Antibiotic‐Antimicrobial Peptide Conjugates

Maria Cristina Bellucci, Carola Romani, Monica Sani, Alessandro Volonterio

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: antimicrobial peptides; antibiotics; ‐lactams; vancomycin; aminoglycosides; chemical conjugation; combination therapy

Online: 25 July 2024 (08:01:30 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.0057.v1

Bioengineering Microbes for Improved Nutritional Value and Health Benefits.

Jatan Pandya, Rachana S Adiga, Akash K, Chadhmika C H, Niveditha K, Debasish Kar

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: bioengineered; recombinant; E. coli; insulin; penicillin; cancer; vitamin B12; replacement therapy; nutrition; mABs

Online: 2 May 2023 (05:04:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0289.v3

Internet Access and Nutritional Intake: Evidence from Rural China

Ping Xue, Xinru Han, Ehsan Elahi, Yinyu Zhao, Xiudong Wang

Subject: Business, Economics And Management, Economics Keywords: internet access; nutritional intake; rural China; propensity score matching

Online: 11 June 2021 (14:54:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0739.v1

Field Application of an Innovative Approach to Assess Honeybee Health and Nutritional Status

Cecilia Rudelli, Roberta Galuppi, Riccardo Cabbri, Thomas Dalmonte, Luca Fontanesi, Giulia Andreani, Gloria Isani

Subject: Biology And Life Sciences, Insect Science Keywords: honeybees, haemolymph proteins, vitellogenin, essential trace elements, Varroa destructor, Nosema spp,

Online: 11 June 2024 (15:09:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0942.v1

Removing Microplastics from Aquatic Environments with Iris 2 Pseudacorus and Lythrum anceps

Yoosun Kim, Kiyoung Park, Jonghyeok Bak, Sueran Choi

Subject: Biology And Life Sciences, Horticulture Keywords: Plastics; Phytoremediation; Aquatic plants

Online: 14 May 2024 (09:03:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1209.v1

Relationship between Family Factors, Food Consumption Behaviors, and Nutritional Status among Muslim School-Age Students in Nakhon Si Thammarat Province, Thailand

Pastraporn Kaewpawong, Kiatkamjorn Kusol

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: food consumption behaviors; nutritional status; Muslim school-age students

Online: 18 June 2024 (11:32:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0992.v1

Efficient Quality Control of Peptide Pools

Gaby Bosc-Bierne, Shireen Ewald, Oliver J. Kreuzer, Michael G. Weller

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: peptide pools; quality control; UHPLC-UV-HRMS; relative quantification; substance confirmation; structure; cost efficiency; CEF; infectious diseases; orbitrap

Online: 15 April 2024 (14:56:29 CEST)

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Abstract: Peptide pools composed of short amino acid sequences have proven to be versatile tools in various research areas and clinical applications. They are powerful tools for epitope mapping, immunotherapy, and vaccine development. Their importance lies in their ability to map complex protein structures, enabling a comprehensive understanding of immune responses and facilitating the identification of potential therapeutic agents. The application of peptide pools also extends to the field of personalized medicine, offering tailored solutions for diseases such as cancer and infectious diseases. Peptide pools are complex mixtures of immunostimulatory antigens primarily intended for T-cell stimulation. They are commercially available in many different compositions and variants. However, unlike other reagents that consist of only one or a few compounds, peptide pools are highly complex products with limited stability. This makes their quality control a major challenge. Quantitative peptide analysis usually requires sophisticated methods, in most cases isotope-labeled standards and reference materials. None of these are routinely available for these products. Synthesis and purification of all labeled peptides might be required. Usually, this approach would be prohibitively laborious and expensive. Therefore, an approach is needed to provide a practical and feasible method for quality control of peptide pools. With insufficient quality control, the use of such products could lead to incorrect experimental results, which would worsen the well-known reproducibility crisis in the biomedical sciences. Here we propose the use of ultra-high performance liquid chromatography (UHPLC) with two detectors, a standard UV detector (at 214 nm) for quantitative analysis and a high-resolution mass spectrometer (HRMS) for identity confirmation. To be cost-efficient and fast, quantification and identification are performed in one chromatographic run. An optimized protocol is shown, and different peak integration methods are compared and discussed. This work was performed using a peptide pool known as CEF, which consists of 32 peptides derived from cytomegalovirus (CMV), Epstein-Barr virus (EBV) and influenza virus, ranging from 8 to 12 amino acids in length.

Preprint REVIEW | doi:10.20944/preprints201810.0036.v1

Perioperative Nutritional Support or Perioperative Fasting?

Piero Chirletti, Noemi Giannetta, Mariachiara Figura, Angelo Cianciulli, Francesca Malandra, Luca Sacco, Sara Dionisi, Emanuele Di Simone, Marco Di Muzio

Subject: Biology And Life Sciences, Food Science And Technology Keywords: ERAS Protocol; nutrition support; fasting; colorectal surgery

Online: 2 October 2018 (22:31:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1467.v1

The Impact of Malnutrition on COPD Outcomes: Role of Mini-Nutritional Assessment (Mna) in Predicting Acute Exacerbations in Patients with Highly Complex COPD and Its Clinical and Prognostic Implications

Domenico Di Raimondo, Edoardo Pirera, Chiara Pintus, Riccardo De Rosa, Martina Profita, Gaia Musiari, Gherardo Siscaro, Antonino Tuttolomondo

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: Malnutrition; Mini Nutritional Assessment (MNA); Chronic Obstructive Pulmonary Disease (COPD); acute exacerbation of COPD (AECOPD); Quality of Life; Frailty; Multimorbidity

Online: 21 June 2024 (02:48:01 CEST)

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Working Paper ARTICLE

Dietary Diversity and Nutritional Adequacy Among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional Analysis

Naomi Cano-Ibáñez, Alfredo Gea, Miguel A. Martínez-González, Jordi Salas-Salvadó, Dolores Corella, M. Dolors Zomeño, Dora Romaguera, Jesús Vioque, Fernando Aros, Julia Wärnberg, J. Alfredo Martínez, Lluis Serra-Majem, Ramón Estruch, Francisco Tinahones, José Lapetra, Xavier Pintó, Josep A. Tur, Antonio García-Ríos, Blanca Riquelme-Gallego, Miguel Delgado-Rodríguez, Pilar Matía, Lidia Daimiel, Vicente Martín, Josep Vidal, Clotilde Vázquez, Emilio Ros, Pilar Buil-Cosiales, Andrés Díaz-López, Rebeca Fernández-Carrión, Montserrat Fitó, Jadwiga Konieczna, Leyre Notario-Barandiaran, Ángel M. Alonso-Gómez, Eugenio Contreras-Fernández, Itziar Abete, Almudena Sánchez-Villegas, Rosa Casas, Araceli Muñoz-Garach, José Manuel Santos-Lozano, Laura Gallardo-Alfaro, Josep Basora, Olga Portoles, Miguel Ángel Muñoz, Manuel Moñino, Salvador Miralles Gisbert, Anai Moreno Rodríguez, Miguel Ruiz-Canela, Antoni Palau Galindo, Karla Alejandra Pérez-Vega, Aurora Bueno-Cavanillas

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Dietary diversity; nutrient adequacy; metabolic syndrome; aging; PREDIMED-Plus study

Online: 18 March 2019 (09:25:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1025.v1

Pre-infection Nutritional Status, Oxidative Stress, and One-Year Long COVID Persistence in Patients Undergoing Hemodialysis: A Prospective Cohort Study

Natalia Stepanova, Lesya Korol, Tetyana Ostapenko, Valeriia Marchenko, Olga Belousova, Lyudmila Snisar, Iryna Shifris, Mykola Kolesnyk

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: long COVID; hemodialysis; controlling nutritional status score; undernutrition; oxidative stress; persistence

Online: 16 April 2024 (11:10:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1174.v1

Nutritional Guidance through Digital Media for Glycemic Control of Women with Gestational Diabetes Mellitus

Marlene Carvalho Teixeira Valença, Marcelo Santucci França, Rosiane Mattar, Roberta Granese, Patricia Medici Dualib, Victor Hugo Salcedo Sanchez, Bianca De Almeida-Pititto, Edward Araujo Júnior, Evelyn Traina

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: gestational diabetes mellitus; nutrition; diet; diet record; telemedicine

Online: 20 March 2024 (12:34:42 CET)

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Working Paper ARTICLE

Improvements in the Ecological and Nutritional Aspects of Down's Syndrome

Loai Aljerf, Mazen Aljurf

Subject: Chemistry And Materials Science, Food Chemistry Keywords: Nutrition system; Carbon footprint; Energy metabolism; Anthropometric; Biomedical treatment

Online: 31 May 2020 (21:01:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0365.v1

Diet and Nutritional Factors in Male (In)Fertility – Underestimated Factors

Kinga Skoracka, Piotr Eder, Liliana Łykowska-Szuber, Agnieszka Dobrowolska, Iwona Krela-Kaźmierczak

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: semen quality; male infertility; nutritional model; diet

Online: 20 April 2020 (14:54:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0501.v1

IGF-1 and IGFBP-1, Possible Predictors of Response to Lifestyle Intervention – Results from Randomized Controlled Trials

Nina M.T. Meyer, Stefan Kabisch, Ulrike Dambeck, Caroline Honsek, Margrit Kemper, Christiana Gerbracht, Ayman M. Arafat, Andreas L. Birkenfeld, Peter E. H. Schwarz, Jürgen Machann, Martin A. Osterhoff, Martin O. Weickert, Andreas F. H. Pfeiffer

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: IGF-axis; lifestyle intervention; intervention response; prediabetes

Online: 8 May 2024 (12:45:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0262.v1

Developing a Lexicon to Measure Food-Elicited Emotions: Standard Methodology Extended to Using the World Wide Web and Social Media

Malamatenia Panagiotou, Aikaterini Gkatzioni, Vasiliki Bountziouka, Konstantinos Gkatzionis

Subject: Biology And Life Sciences, Food Science And Technology Keywords: emotion lexicon; self-report questionnaires; food; consumer studies; measurement

Online: 5 September 2024 (06:15:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1668.v2

Comparison of the Proteome of Staphylococcus aureus Planktonic Culture and 3-Day Biofilm Reveals Potential Role of Key Proteins in Biofilm

Md Arifur Rahman, Ardeshir Amirkhani, Durdana Chowdhury, Karen Vickery, Honghua Hu

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Staphylococcus aureus; biofilms; proteomics; TMT-MS; virulence factors; biosynthetic processes; stress responses.

Online: 29 May 2024 (09:12:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2340.v1

Machine Learning Method for Approximate Solutions for Reaction-Diffusion Equations with Multivalued Interaction Functions

Pavlo O. Kasyanov, Oleksiy V. Kapustyan, Liudmyla B. Levenchuk, Vladyslav R. Novykov

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: reaction-diffusion equations; multivalued interaction functions; machine learning; physics-informed neural networks; approximate solutions

Online: 30 July 2024 (00:20:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1266.v1

Typology of Business Incubators in Spain according to the Stages of Startups Incubation

Ana Asensio-Ciria, Carmen De-Pablos-Heredero, Francisco José Blanco Jiménez, Antón Garcia Martínez

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: startups; business incubators; entrepreneurship; advice; pre-incubation; incubation; graduation; viability; sustainability

Online: 19 August 2024 (17:54:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0649.v1

Determination of Recovery by Healing or Compensation Using Multifrequency Vestibular Tests and Subjective Functional Scales in a Human Model of Vestibular Neuritis

Enrico Armato, Georges Dumas, Flavio Perottino, Matthieu Casteran, Philippe Perrin

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Vestibular Neuritis; Recovery by healing; Recovery by compensation; Dizziness Handicap Inventory; Bithermal Caloric Test - Video Head Impulse Test; Skull Vibration-Induced Nystagmus Test

Online: 12 August 2024 (03:02:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1585.v1

Typology of Business Incubators in Spain according to the Stages of Startups Incubation

Ana Asensio-Ciria, Carmen De-Pablos-Heredero, Francisco José Blanco Jiménez, Antón García Martínez

Subject: Business, Economics And Management, Business And Management Keywords: startups; business incubators; entrepreneurship; advice; pre-incubation; incubation; graduation; viability; sustainability

Online: 26 March 2024 (10:25:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.1824.v1

Water Resources of the Belarusian Polesie under the Influence of Anthropogenic Factors Using the Example of the Lan River

Alexander Volchak, Ivan Kirvel, Sergey Parfomuk, Svetlana Sidak

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: runoff; anthropogenic factors; climate changes; forecast; Lan River; Loktyshi fish farm

Online: 23 July 2024 (18:06:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0333.v1

Unveiling Respiratory Muscle Strength in Duchenne Muscular Dystrophy: Beyond Spirometry and Nutritional Impact

Mine Yüksel Kalyoncu, Yasemin Gökdemir, Cansu Yılmaz Yeğit, Mürüvvet Yanaz, Ainur Gulieva, Merve Selçuk, Şeyda Karabulut, Neval Metin Çakar, Pınar Ergenekon, Ela Erdem Eralp, Gülten Öztürk, Olcay Unver, Dilsad Turkdogan, Yavuz Sahbat, Ahmet Hamdi Akgülle, Fazilet Karakoç, Bülent Karadag

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Duchenne muscular dystrophy; sniff nasal inspiratory pressure; supine spirometry; diaphragm

Online: 6 June 2024 (07:44:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0038.v1

Chemical Fingerprint Analysis and Quantitative Analysis of Rosa Rugosa by UPLC-DAD

Sanawar Mansur, Rahima Abdullab, Amatjan Ayubicb, Haji Akbar Aisa

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Rosa rugosa; UPLC-DAD; quality control; fingerprint

Online: 7 December 2016 (11:11:00 CET)

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