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Preprint ARTICLE | doi:10.20944/preprints202107.0604.v2

RT-qPCR Diagnostics: The “Drosten” Sars-Cov-2 Assay Paradigm

Stephen Bustin, Sara Kirvell, Jim F Huggett, Tania Nolan

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19; reverse transcription; qPCR; SARS-CoV-2; molecular diagnosis

Online: 3 August 2021 (15:34:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202004.0216.v1

Development of a Field-deployable RT-qPCR Workflow for COVID-19 Detection

Raphael Nyaruaba, Bo Zhang, Caroline Muema, Elishiba Muturi, Greater Oyejobi, Jin Xiong, Bei Li, Zhengli Shi, Caroline Mwaliko, Junping Yu, Xiaohong Li, Hongping Wei

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: COVID-19; SARS-CoV-2; field work; community; diagnosis; rapid detection; inactivation; RT-qPCR

Online: 14 April 2020 (08:41:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1328.v1

Proteomics-Based RT-qPCR and Functional Analysis of 18 Genes in Metronidazole Resistance of Bacteroides fragilis

Bakhtiyar Mahmood, Anna Paunkov, Malgorzata Kupc, Katalin Burián, Erzsébet Nagy, David Leitsch, József Sóki

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Bacteroides, metronidazole, nim, resistance mechanism, RT-qPCR

Online: 17 January 2024 (13:06:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0600.v1

Real-Time Monitoring of SARS-CoV-2 Variants in Oklahoma Wastewater through Allele-Specific RT-qPCR

Kristen Shelton, Gargi N Deshpande, Gilson J Sanchez, Jason Vogel, A Caitlin Miller, Gabriel Florea, Erin R Jeffries, Kara B. De Leon, Bradley Stevenson, Katrin Gaardbo Kuhn

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: wastewater surveillance; SARS-CoV-2; variant; RT-qPCR; sequencing; early warning; demography; Oklahoma

Online: 9 September 2024 (08:42:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202106.0320.v1

Inherent Bias of SARS-CoV-2 RNA Quantification for Wastewater Surveillance Due to Variable RT-qPCR Assay Parameters

Aaron Bivins, Devrim Kaya, Kyle Bibby, Stuart Simpson, Stephen Bustin, Orin Shanks, Warish Ahmed

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: RT-qPCR; assay validity; standard curve; quality assurance; quality control; wastewater surveillance

Online: 11 June 2021 (14:10:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0011.v1

Simulation Analysis of Solution Transportation Absorption Chiller with the Capacity from 25 RT to 1000 RT

Koji Enoki, Fumi Watanabe, Seigo Tanaka, Atsushi Akiwawa, Toshitaka Takei

Subject: Engineering, Energy And Fuel Technology Keywords: absorption chiller; thermal energy transportation; solution transportation; ammonia-water; COP; simulation

Online: 4 February 2017 (07:49:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1127.v1

Machine Learning Application to Brain Diseases Detection

Aleksandar Simović, Maja Lutovac-Banduka, Kristina Davidović, Snežana Lekić

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; application; classification; brain diseases; detection

Online: 17 November 2023 (15:32:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202209.0439.v1

SARS-CoV-2 Detection in Fecal Samples in Sym-asymptotic Patients with Typical Findings of COVID-19 on Ag-RDT and SARS-CoV-2 RT-PCR Tests

Richard Odongo Magwanga, Benson Onyango, Alfred Ochieng, Shehu Shagari Awandu, Pamela Were, Joy Nyangasi Kirungu, Marceline Adhiambo Oloo, Erick Muok, Stephen Munga, Fredrick Ogutu, Angeline Orwa, Fredrick Okumu, Clayton Onyango, Dorothy Awuor, Francis Orata, Justine Ochieng’-Midega, Bonface Oure, Regina Nyunja, Fredrick Ade, Sharley Indechi, Erick Okuto, Benson Estambale

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: COVID19; SARS-CoV-2 virus; Oro-nasopharyngeal; fecal; vaccination; asym-symptomatic; rapid diagnostic test

Online: 28 September 2022 (11:51:21 CEST)

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Coronavirus is a disease caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which emerged as a global pandemic in 2019 from Wuhan, China. Since its emergence, it has caused immense suffering to human life, 6.27 million lives have been lost, movement curtailed and social dynamics disrupted. The golden standard for getting samples for SARS-CoV-2 detection is through oral- nasopharyngeal swab, this method of sample collection is invasive and uncomfortable, thus stigmatized the general population, and thereby impeded the progress of controlling the spread through mass testing. Being a contact disease, mechanisms to encourage mass testing is key to reduce the spread. This study thus developed a complimentary sample type to test for SARS-CoV-2, the use of human feces. Fecal samples were collected from 100 asym-symptomatic individuals suspected to be infected with COVID-19, virus RNA was then extracted and profiled through Real Time Polymerase Chain Reaction (RT-qPCR). The antigen rapid diagnostic test revealed high positivity rate of 44%, but the real time polymerase chain reaction results on nasopharyngeal and fecal samples revealed a significant variation, high number of the patients tested positive with stool samples compared to the nasopharyngeal swabs, with 43 and 37%, respectively. SARS-CoV-2 virus was detected in both symptomatic and asymptomatic individuals; however, the symptomatic registered a higher positivity of 25% compared to 20% among the asymptomatic patients. Vaccination only lowered the risk of infection, fully and partially vaccinated lowered the infection level to 10% compared to 20% among the unvaccinated. Finally, gender parity in relation to COVID19 was evaluated, more females (56%) compared to males were recruited in this study, out of which (20; 43.4%) were positive, and 26 (56.6%) were negative based on fecal RT-qPCR outcomes. Based on the outcome of this study, rapid diagnostic test (Ag-RDT) however cheap and or fast does not provide accurate information, moreover, the virus does not stay longer within the Oro-nasopharyngeal region, thus the invalid or negative results, thus use of feces should be adopted as a confirmatory test to ascertain the COVID19 status of an individual.

Preprint ARTICLE | doi:10.20944/preprints202305.0869.v1

qPCR System for Alongshan Virus Detection

Alexander Litov, Egor Okhezin, Ivan Kholodilov, Alexandra Polienko, Galina Karganova

Subject: Biology And Life Sciences, Virology Keywords: Jingmenvirus group; Alongshan virus; qPCR; Flavivirus; Yanggou tick virus; tick-borne viruses

Online: 11 May 2023 (14:25:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0446.v1

Symbolic Analysis of Classical Neural Networks for Deep Learning

Maja Lutovac-Banduka, Igor Franc, Vladimir Milićević, Nemanja Zdravković, Nikola Dimitrijević

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; visual programming language; closed-form expression; theoretical justification; feature extraction; complexity; optimization and validation

Online: 7 November 2023 (11:25:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1436.v1

Structural Health Monitoring for Prefabricated Building Envelope under Stress Tests

Laura Vandi, Maria Teresa Calcagni, Francesco Belletti, Giuseppe Pandarese, Milena Martarelli, Gian Marco Revel, Vincent Docter, Alessandro Pracucci

Subject: Engineering, Architecture, Building And Construction Keywords: building envelope; facade; structural health monitoring; fiber optic sensor; fiber brag grating; IoT

Online: 25 March 2024 (07:11:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0152.v1

Self-Cleaning Solar Mirrors Coatings: From the Laboratory Scale to Prototype Field Tests

Anna Castaldo, Emilia Gambale, Giuseppe Vitiello, Giuseppe Cara

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: solar mirrors; self-cleaning; coatings; sputtering; AlN; prototype; test on field

Online: 2 July 2024 (02:57:49 CEST)

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Preprint REVIEW | doi:10.20944/preprints202311.1089.v1

White Paper Textile Fibre Recycling Technologies

Birgit Stubbe, Stijn Van Vrekhem, Sofie Huysman, Rémi G. Tilkin, Isabel De Schrijver, Myriam Vanneste

Subject: Chemistry And Materials Science, Paper, Wood And Textiles Keywords: textile recycling; fibre-to-fibre recycling; textile sorting; textile disassembly; digital textile platforms

Online: 17 November 2023 (08:49:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0450.v1

Performance Assessment of Presurgical Tests in Temporal Lobe Epileptic Patients

Jesús Pastor, Lorena Vega-Zelaya, Rafael G. Sola, Paloma Pulido

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: electroencephalography; Engel’s grade, magnetic resonance imaging; multiple binary logistic model; single photon emission computed tomography; video-electroencephalography.

Online: 7 February 2024 (13:51:24 CET)

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The performance of the presurgical test (preSurg) for temporal lobe epilepsy (TLE) was evaluated via video-electroencephalography (VEEG), electroencephalography (EEG), 99mTc-HmPAO single-photon emission tomography (SPECT) and 1.5 T magnetic resonance imaging (MRI) in a group of 112 men (37.0 ± 1.1 years) and 106 women (39.7 ± 1.1 years) operated on for TLE. The epileptic zone (EZ) was adequately identified to determine whether the patient reached an Engel I grade (EI) at least one year postop. Accuracy was evaluated by the coefficient α, ranging from 3 (when result = EZ) to 2 (result in the same hemisphere as the EZ), 1 (noninformative result) or 0 (EZ in the contralateral hemisphere). The simplicity of diagnosis was defined as the number of preSurg surgeries needed to identify the EZ. EI was obtained in 85.8% of patients even though 42.2% of patients had noninformative MRI results. For preSurg α was (mean ± SEM) = VEEG (2.83 ± 0.04) > MRI (2.14 ± 0.08) > EEG (1.87 ± 0.09) > SPECT (1.71 ± 0.09). The accuracy (combination of sensitivity and specificity) was calculated as follows: VEEG (0.797) > MRI (0.518) > EEG (0.446) > SPECT (0.360). The likelihood positive ratio was greater, and the likelihood negative ratio was lower for VEEG. The most relevant factor for the regression model was VEEG (3.106) > MRI (2.558) > EEG (1.905), and the factors were not significantly related to SPECT. EZs in EI patients with low simplicity were identified mainly by VEEG. A very good postoperative outcome can be obtained even in TLE patients with no lesions on MRI. The VEEG is the most reliable preSurg test and may be the only reliable test for patients with very low simplicity (i.e., difficult).single paragraph of about 200 words maximum. For research articles, abstracts should give a pertinent overview of the work. We strongly encourage authors to use the following style of structured abstracts, but without headings: (1) Background: Place the question addressed in a broad context and highlight the purpose of the study; (2) Methods: briefly describe the main methods or treatments applied; (3) Results: summarize the article’s main findings; (4) Conclusions: indicate the main conclusions or interpretations. The abstract should be an objective representation of the article and it must not contain results that are not presented and substantiated in the main text and should not exaggerate the main conclusions.

Preprint ARTICLE | doi:10.20944/preprints201703.0117.v1

Goodness-of-Fit Tests for Copulas of Multivariate Time Series

Bruno Rémillard

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: goodness-of-fit; time series; copulas; GARCH models

Online: 16 March 2017 (09:38:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.0573.v1

Enhancing Metabolic Syndrome Detection through Blood Tests Using Advanced Machine Learning

Petros Paplomatas, Dimitris Rigas, Athanasia Sergounioti, Aristidis Vrahatis

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Metabolic Syndrome (MetS); Machine Learning (ML); Feature Importance; Borda Count Method; Predictive Modeling; Ensemble Models; Cross-Validation; Non-Invasive Diagnostics

Online: 10 June 2024 (12:50:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1468.v1

Diagnostic Efficiency of CTV and HSVd for Early and Mixed Infections Using Bioamplification in Citrus Arizona 861-S1 and RT‒PCR Compared to Direct RT‒PCR

Claudio A. Henriquez, Natalia Riquelme, Alejandra Larach, Ximena Besoain

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Virus-viroid detection; Mixed infections; Comparison of diagnostic methods; CTV; HSVd; Bioamplification

Online: 19 January 2024 (07:52:21 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202408.1591.v1

Comparison of Chest Ct Findings and Pulmonary Function Tests in Non-symptomatic Children with Rheumatic Diseases

Spyridon Prountzos, Kyveli Chiotopoulou, Katerina Kourtesi, Evdoxia Sapountzi, Dafni Moriki, Elpiniki Kartsiouni, Efthymia Alexopoulou, Konstantinos Douros, Lampros Fotis

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Lung; Pediatrics; Rheumatic Diseases; Spirometry; Tomography, X-ray Computed

Online: 21 August 2024 (16:00:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1298.v2

Development of qPCR Detection Kit for Langya Henipavirus L Gene

Kunbo Yuan, Haoqing Zhu, Tianyu Jiang, Mengting Xu, Shihan Du, Samuel Ken-En Gan

Subject: Biology And Life Sciences, Virology Keywords: Langya Henipavirus; primer design; qPCR; detection kit

Online: 22 January 2024 (10:42:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1369.v1

FlashPCR: Revolutionising qPCR by Accelerating Amplification through Low ∆T Protocols

Stephen Andrew Bustin, Sara Kirvell, Tania Nolan, Gregory L. Shipley

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Reverse transcription; qPCR; COVID-19; molecular diagnostics; point-of-care

Online: 18 January 2024 (12:01:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1377.v1

Derivation of Creep Parameters for Surrounding Rock Through Creep Tests and Deformation Monitoring Data: Assessing Tunnel Lining Safety

Jiangrong Pei, Lipeng Liu, Xiaogang Wang, Yuanqiao Ling

Subject: Engineering, Civil Engineering Keywords: tunneling project; creep test; parameter inversion; timing of lining

Online: 23 February 2024 (13:27:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202405.2064.v1

TaqMan qPCR Detection and Quantification of Phytophthora cinnamomi in Soil and Plant Tissues for Walnut Disease Management

Anita Haegi, Laura Luongo, Salvatore Vitale, Lorenza Tizzani, Alessandra Belisario

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: real-time PCR; tree decline; diagnostic; early detection; soil detection

Online: 30 May 2024 (13:47:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1028.v1

Performance Evaluation of Calcined Phosphogypsum Reinforced with Basalt Fiber and Calcium Carbonate Whiskers: A Study on Individual and Mixed Tests

Jiang Yong, Huo Jichuan, Lei Yonglin, Jia Lujun

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Calcined phosphogypsum; Basalt fiber; Calcium carbonate whisker; Strength

Online: 19 February 2024 (09:25:27 CET)

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Preprint REVIEW | doi:10.20944/preprints202307.0247.v1

Alternate antimicrobial therapies and their companion tests

Sriram Kalpana, Wan-Ying Lin, Yu-Chiang Wang, Yiwen Fu, Hsin-Yao Wang

Subject: Biology And Life Sciences, Life Sciences Keywords: antimicrobial resistance, antimicrobial peptides, aptamers, companion diagnostics, bacteriophages, companion diagnostics

Online: 4 July 2023 (14:08:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0081.v2

The Efficacy of Core Stability Assessment as a Determiner of Performance in Dynamic Balance and Agility Tests.

Kieran McCartney, Jacky Forsyth

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: core stability; balance; agility

Online: 9 August 2016 (11:09:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1757.v1

Development of qPCR and LAMP Assays for the Surveillance and Diagnosis of Herpes B Virus Infection

Murasaki Amano, Krittiga Sapkanarak, Wipaporn Thbthimthong, Suthirote Meesawat, Taratorn Kemthong, Nutchanat Suttisan, Haruka Abe, Suchinda Malaivijitnond, Jiro Yasuda

Subject: Biology And Life Sciences, Virology Keywords: Herpes B virus; zoonosis; LAMP; surveillance; cynomolgus macaque

Online: 26 September 2023 (13:39:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1052.v1

Relationship between Spine Range of Motion and Functional Tests in University Students: The Role of Demographic Factors

Nela-Tatiana Balint, Bogdan Alexandru Antohe, Huseyin Sahin Uysal, Mihaela-Alina Cristuta, Marinela Rață

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: spine; posture; students; deviations

Online: 16 April 2024 (10:58:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0196.v1

Molecular Identification of Fungal Species by Multiplex-qPCR in Candidal Vulvovaginitis Specimens and Antifungal Susceptibility

Inés Arrieta-Aguirre, Pilar Menéndez-Manjón, Giulia Carrano, Ander Diez, Íñigo Fernandez de Larrinoa, María-Dolores Moragues

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Vulvovaginal Candidiasis; qPCR; Candida species, antifungal susceptibility, resistance-related mutations

Online: 3 November 2023 (04:02:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.2136.v1

Multiplex Real-Time RT-PCR Assays for Detection and Differentiation of Porcine Enteric Coronaviruses

Christina M. Lazov, Alice Papetti, Graham J. Belsham, Anette Bøtner, Thomas Bruun Rasmussen, Maria Beatrice Boniotti

Subject: Biology And Life Sciences, Virology Keywords: Virus diagnosis; RNA; recombinant virus; alphacoronavirus; deltacoronavirus; porcine epidemic diarrhea virus (PEDV); transmissible gastroenteritis virus (TGEV); swine enteric coronavirus (SeCoV); porcine deltacoronavirus (PDCoV)

Online: 29 June 2023 (13:22:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0649.v1

Determination of Recovery by Healing or Compensation Using Multifrequency Vestibular Tests and Subjective Functional Scales in a Human Model of Vestibular Neuritis

Enrico Armato, Georges Dumas, Flavio Perottino, Matthieu Casteran, Philippe Perrin

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Vestibular Neuritis; Recovery by healing; Recovery by compensation; Dizziness Handicap Inventory; Bithermal Caloric Test - Video Head Impulse Test; Skull Vibration-Induced Nystagmus Test

Online: 12 August 2024 (03:02:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0009.v1

A Novel Fluorescent Sensor Based on Aptamer and Qpcr for Determination of Glyphosate in Tap Water

Yong Shao, Run Tian, Jiaqi Duan, Miao Wang, Jing Cao, Zhen Cao, Guangyue Li, Fen Jin, Yongxin She, A. M. El-Aty

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Glyphosate; Aptamer; qPCR; SYBR Green I; sensor

Online: 1 December 2022 (04:00:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0991.v1

Potential Performance of Two New RT-PCR and RT-q PCR Methods for Multiplex Detection of Dengue Virus Serotypes 1-4 and Chikungunya Virus in Mosquitoes Allowing Efficient Entomological Surveillance of Both Vector-Borne Diseases

Michel Kiréopori Gomgnimbou, Louis robert wendyam BELEM, Etienne Bilgo, Miriam Félicité Amara, Zouera Laouali, Ali Ouari, Toussaint Bayala, Kobo Gnada, Raymond Kharlis Yao, Moussa Namountougou, Ibrahim Sangaré

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: multiplex rt-pcr; multiplex rt-qpcr; molecular detection; dengue virus; chikungunya virus; mosquitoes; Burkina Faso

Online: 12 July 2024 (08:43:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0250.v1

Nontuberculous Mycobacteria Prevalence in Bats’ Guano from Caves and Attics of Buildings Studied by Culture and qPCR Examinations

Ivo Pavlik, Vit Ulmann, Helena Modra, Milan Gersl, Barbora Rantova, Jan Zukal, Katerina Zukalova, Ondrej Konecny, Vlastislav Kana, Pavel Kubalek, Vladimir Babak, Ross Tim Weston

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: non-tuberculous mycobacteria (NTM); mycobacteria other than tuberculosis (MOTT); saprophytic environmental mycobacteria; risk groups of microorganisms; Microchiroptera

Online: 18 October 2021 (14:54:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0024.v1

Normative Data for the D-KEFS Color-Word Interference and Trail Making Tests Adapted in Greek Adult Population 20–49 Years Old

Marianna Tsatali, Fotini Surdu, Andromachi Konstantinou, Despina Moraitou

Subject: Social Sciences, Psychology Keywords: D-KEFS; Color-Word Interference; executive functions; normative data; Trail Making Test

Online: 2 September 2024 (08:44:58 CEST)

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Background: This study was designed to adapt the Delis-Kaplan Executive System (D-KEFS) version of the Color-Word Interference (CWIT) and Trail making Tests (TMT) in Greek adult population from 20 to 49 years old, since it is of research as well as clinical importance to detect executive functions’ impairment in young adults with neurological or/and psychiatric conditions. Aims: Norms for the Greek adult population have been calculated to be available for neuropsychologists and health professionals who work in relevant settings. Methods: The study sample consisted of 101 healthy adults (41% male and 60% female), aged 20 to 49 years (M=32.16, SD=11.57) with education from 12 to 19 years of schooling (M=14.51, SD= .89). Pearson correlation test as well as chi square test were conducted to examine potential associations between gender, age, education, and participants’ performance. Afterwards, we calculated normative data using raw scores and transformed them to percentile scores. Finally, Greek norms were compared to the original raw scores, which were transformed in scaled scores by Delis et al. (2001). Results: The findings showed that age was the only variable which affected CWIT, whereas level of education as well as age were predictive factors for most TMT conditions, except for the visual scanning test (Condition 1). Gender did not affect both tests. Finally, D-KEFS norms for CWIT and TMT are available for Greek adult population to help clinicians detect executive functions’ deficits and therefore adjust tailored therapeutic strategies. Additionally, it is of great importance to use these tests for research purposes. Conclusion: Given that executive functions are assumed as high- level skills, which are highly related to everyday functionality, adapted tests contribute not only to assess the progression of any existing neurological as well as psychiatric disorders, but they can also be used to evaluate patients’ ability to live independently, as well as their access to work.

Preprint ARTICLE | doi:10.20944/preprints202405.1113.v1

The Effect of Sample Configuration on the Measurement of the Bending Properties of Extruded Polystyrene Using Three-Point, Four-Point, and Compression Bending Tests

Hiroshi Yoshihara, Masahiro Yoshinobu, Makoto Maruta

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: extruded polystyrene; three-point bending test; four-point bending test; compression bending test; Young’s modulus; proportional limit stress; bending strength

Online: 17 May 2024 (04:17:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0297.v3

Insulin in Amyotrophic Lateral Sclerosis: Impairment, Tests and Treatment

Ari Rappoport

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: ALS; frontotemporal dementia; insulin; diabetes

Online: 24 January 2023 (10:25:55 CET)

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Preprint REVIEW | doi:10.20944/preprints201702.0002.v1

Tests and Problems of the Standard Model in Cosmology

Martin Lopez-Corredoira

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Cosmology; Observational cosmology; Origin, formation, and abundances of the elements; dark matter; dark energy; superclusters; large-scale structure of the Universe

Online: 1 February 2017 (16:06:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202108.0190.v1

Accuracy and Repeatability Tests on HoloLens 2 and HTC Vive

Inês Soares, Ricardo Sousa, Marcelo Petry, António Moreira

Subject: Computer Science And Mathematics, Computer Science Keywords: Programming by Demonstration; Virtual Reality; Augmented Reality; Accuracy; Repeatability

Online: 9 August 2021 (10:42:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.0179.v1

Simulational Tests of the Rouse Model

George Phillies

Subject: Physical Sciences, Condensed Matter Physics Keywords: computer simulations polymeric fluid; polymer melt; Rouse model; Rouse dynamics

Online: 4 May 2023 (03:56:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202104.0481.v1

Minimizing Errors in RT-PCR Detection and Quantification of SARS-CoV-2 RNA for Wastewater Surveillance

Warish Ahmed, Stuart Simpson, Paul Bertsch, Kyle Bibby, Aaron Bivins, Linda Blackall, Silvia Bofill-Mas, Albert Bosch, Joao Brandao, Phil Choi, Mark Ciesielski, Erica Donner, Nishita D'Souza, Andreas Farnleitner, Daniel Gerrity, Raul Gonzalez, John Griffith, Pradip Gyawali, Charles Haas, Kerry Hamilton, Chanditha Hapuarachchi, Valerie Harwood, Rehnuma Haque, Greg Jackson, Stuart Khan, Wesaal Khan, Masaaki Kitajima, Asja Korajkic, Giuseppina La Rosa, Blythe Layton, Erin Lipp, Sandra McLellan, Brian McMinn, Gertjan Medema, Suzanne Metcalfe, Wim Meijer, Jochen Mueller, Heather Murphy, Colleen Naughton, Rachel Noble, Sudhi Payyappat, Susan Petterson, Tarja Pitkanen, Veronica Rajal, Brandon Reyneke, Fernando Roman, Joan Rose, Marta Rusinol, Michael Sadowsky, Laura Sala-Comorera, Yin Xiang Setoh, Samendra Sherchan, Kwanrawee Sirikanchana, Wendy Smith, Joshua Steele, Rosalie Sabburg, Erin Symonds, Phong Thai, Kevin Thomas, Josh Tynan, Simon Toze, Janelle Thompson, Andy Whiteley, Judith Wong, Daisuke Sano, Stefan Wuertz, Irene Xagoraraki, Qian Zhang, Amity Zimmer-Faust, Orin Shanks

Subject: Environmental And Earth Sciences, Waste Management And Disposal Keywords: COVID-19; SARS-CoV-2; Wastewater; Surveillance; False-positive; False-negative; RT-PCR

Online: 19 April 2021 (13:08:13 CEST)

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Wastewater surveillance for pathogens using the reverse transcription-polymerase chain reaction (RT-PCR) is an effective, resource-efficient tool for gathering additional community-level public health information, including the incidence and/or prevalence and trends of coronavirus disease-19 (COVID-19). Surveillance of SARS-CoV-2 in wastewater may provide an early-warning signal of COVID-19 infections in a community. The capacity of the world’s environmental microbiology and virology laboratories for SARS-CoV-2 RNA characterization in wastewater is rapidly increasing. However, there are no standardized protocols nor harmonized quality assurance and quality control (QA/QC) procedures for SARS-CoV-2 wastewater surveillance. This paper is a technical review of factors that can lead to false-positive and -negative errors in the surveillance of SARS-CoV-2, culminating in recommendations and strategies that can be implemented to identify and mitigate these errors. Recommendations include, stringent QA/QC measures, representative sampling approaches, effective virus concentration and efficient RNA extraction, amplification inhibition assessment, inclusion of sample processing controls, and considerations for RT-PCR assay selection and data interpretation. Clear data interpretation guidelines (e.g., determination of positive and negative samples) are critical, particularly during a low incidence of SARS-CoV-2 in wastewater. Corrective and confirmatory actions must be in place for inconclusive and/or potentially significant results (e.g., initial onset or reemergence of COVID-19 in a community). It will also be prudent to perform inter-laboratory comparisons to ensure results are reliable and interpretable for ongoing and retrospective analyses. The strategies that are recommended in this review aim to improve SARS-CoV-2 characterization for wastewater surveillance applications. A silver lining of the COVID-19 pandemic is that the efficacy of wastewater surveillance was demonstrated during this global crisis. In the future, wastewater will play an important role in the surveillance of a range of other communicable diseases.

Preprint ARTICLE | doi:10.20944/preprints202102.0525.v1

Exploring New Scaffolds for the Dual Inhibition of HIV-1 Rt Polymerase and Ribonuclease Associated Functions

Rita Meleddu, Angela Corona, Simona Distinto, Filippo Cottiglia, Serenella Deplano, Lisa Sequeira, Daniela Secci, Alessia Onali, Erica Sanna, Francesca Esposito, Italo Cirone, Francesco Ortuso, Stefano Alcaro, Enzo Tramontano, Peter Matyus, Elias Maccioni

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: HIV-RT; ribonuclease H; dual inhibitors; docking; putative binding

Online: 23 February 2021 (15:51:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202003.0299.v1

Applying Artificial Intelligence Techniques for Prediction of Neurodegenerative Disorders: A Comparative Case-Study on Clinical Tests and Neuroimaging Tests with Alzheimer’s Disease

Ahmed Abdullah Farid, Gamal Selim, Hatem Khater

Subject: Computer Science And Mathematics, Information Systems Keywords: Data Mining; Alzheimer’s Dementia; Composite Hybrid Feature Selection; Machine learning; stack ‎Hybrid Classification; AI; MRI; Neuroimaging; MPEG7 edge histogram feature extraction; CNN

Online: 19 March 2020 (11:25:01 CET)

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Alzheimer's disease (AD) detection acting as an essential role in global health care due to misdiagnosis and sharing many clinical sets with other types of dementia, and costly monitoring the progression of the disease over time by magnetic reasoning imaging (MRI) with consideration of human error in manual reading. This paper goal a comparative study on the performance of data mining techniques on two datasets of Clinical and Neuroimaging Tests with AD. Our proposed model in the first stage, Apply clinical medical dataset to a composite hybrid feature selection (CHFS), for extract new features to select the best features due to eliminating obscures features, In parallel with Apply a novel hybrid feature extraction of three batch edge detection algorithm and texture from MRI images dataset and optimized with fuzzy 64-bin histogram. In the second stage, we applied a clinical dataset to a stacked hybrid classification(SHC) model to combine Jrip and random forest classifiers with six model evaluations as meta-classifier individually to improve the prediction of clinical diagnosis. At the same stage of improving the classification accuracy of neuroimaging (MRI) dataset images by applying a convolution neural network (CNN) in comparison with traditional classifiers, running on extracted features from images. The authors have collected the clinical dataset of 426 subjects with (1229 potential patient sample) from oasis.org and (MRI) dataset from a benchmark kaggle.com with a total of around ~5000 images each segregated into the severity of Alzheimer's. The datasets evaluated using an explorer set of weka data mining software for the analysis purpose. The experimental show that the proposed model of ‏(CHFS) feature extraction ‏ lead to effectively reduced the false-negative rate with a relatively high overall accuracy with a stack hybrid classification of support vector machine (SVM) as meta-classifier of 96.50% compared to 68.83% of the previous result on a clinical dataset, Besides a compared model of CNN classification on MRI images dataset of 80.21%. The results showed the superiority of our CHFS model in predicting Alzheimer's disease more accurately with the clinical medical dataset in early-stage compared with the neuroimaging (MRI) dataset. The results of the proposed model were able to predict with accurately classify Alzheimer's clinical samples at a low cost in comparison with the MRI-CNN images model at the early stage and get a good indicator for high classification rate for MRI images when applying our proposed model of SHC.

Working Paper ARTICLE

Viscoelastic Behaviour from Complementary Forced-Oscillation and Micro-Creep Tests

Ian Jackson

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: viscoelasticity; anelasticity; creep function; forced-oscillation methods; micro creep methods

Online: 13 October 2019 (16:55:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0061.v1

The Fiber-Optic Rotational Seismograph – Laboratory Tests and Field Application

Leszek R. Jaroszewicz, Anna Kurzych, Zbigniew Krajewski, Michal Dudek, Jerzy K. Kowalski, Krzyztof P. Teisseyre

Subject: Environmental And Earth Sciences, Environmental Science Keywords: rotational seismograph; fiber optic sensor; rotational events; seismology; rotational seismology

Online: 6 May 2019 (12:09:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0156.v1

The Use of Hydrodynamic Cavitation to Improve the Anaerobic Digestion of Waste from Dairy Cattle Farming – from Laboratory Tests to Large-Scale Agricultural Biogas Plant

Marcin Dębowski, Joanna Kazimierowicz, Anna Nowicka, Magda Dudek, Marcin Zieliński

Subject: Engineering, Energy And Fuel Technology Keywords: cattle manure; milking station; anaerobic digestion; pretreatment; hydrodynamic cavitation; biogas; methane; energy efficiency

Online: 6 March 2024 (04:05:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints201901.0212.v1

One-tube RT-PCR for the Simultaneous Detection and Typing Duck Hepatitis A Virus Subtypes 1 and 3

Xueming Chen, Yuhuan Chen, Chunguo Liu, Xiaojun Li, Hongyu Liu, Xiaofei Bai, Ming Liu, Yun Zhang

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: DHAV-1; DHAV-3; Phylogenetic analysis; One-tube RT-PCR; Simultaneously

Online: 22 January 2019 (11:08:19 CET)

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Working Paper REVIEW

Lorentz Invariance Violation Tests in Astroparticle Physics

Humberto Martínez-Huerta, Rodrigo Guedes Lang, Vitor de Souza

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Gamma rays; UHECR; Lorentz invariance violation

Online: 15 May 2020 (15:25:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0125.v1

Up-regulation of Lamin A/C Expression in Epstein-Barr Virus Immortalized B Cells and Burkitt Lymphoma Cell Lines of Activated B Cell Phenotype

Ferenc Bánáti, Anita Koroknai, Kálmán Szenthe, Tamás Tereh, Nóra Kovács, Anita Hidasi, Barbara Bánkuti, Krisztina Buzás, Frederic Lemnitzer, Zsolt Ruzsics, Susan Szathmary, Hans Wolf, Dániel Salamon, János Minárovits, Hans-Helmut Niller

Subject: Biology And Life Sciences, Virology Keywords: Lamin, EBV latency, transformation, epigenetic regulation, activated B cell

Online: 24 November 2016 (17:53:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.1200.v1

Assessment of Rapid Antigen Diagnostic Tests at Mass Events: Identifying Optimal Floor Plan Configurations for Enhanced Efficiency

Anas A Khan, Ahmad F Turki

Subject: Public Health And Healthcare, Health Policy And Services Keywords: COVID-19 Testing; Queueing Theory; M/M/c Model; Mass Gatherings; Operational Efficiency; Agile Management; System Throughput; Public Health Emergency Management; Antigen Testing; Process Optimization

Online: 16 August 2024 (04:53:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0256.v1

Structural Analysis and Experimental Tests of a Morphing Flap Scaled Model

Mürüvvet Sinem SICIM DEMIRCI, Rosario PECORA, Luca CHIANESE, Massimo Viscardi, Metin Orhan KAYA

Subject: Engineering, Aerospace Engineering Keywords: Morphing structures; Smart aircraft; Morphing flap; Adaptive systems; Intelligent systems; Finger-like ribs; Mechanical systems; Large airplanes; Wind tunnel tests; Large-scale morphing architectures; Computational Fluid Dynamics (CFD) analysis; Variable camber airfoil

Online: 5 August 2024 (11:09:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2511.v1

Deep Indentation Tests of Soft Materials Using Mobile and Stationary Devices

Joanna Nowak, Mariusz Kaczmarek

Subject: Engineering, Mechanical Engineering Keywords: indentation test; mechanical parameters; soft materials; phantoms; objectivity of measurements; mobile and stationary apparatus

Online: 31 July 2024 (08:49:57 CEST)

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Working Paper ARTICLE

New Formula of Inertial Force and Tests in Condensed Matter Physics

Zhong-Yue Wang

Subject: Physical Sciences, Theoretical Physics Keywords: mass; energy; gravity; inertial force; principle of equivalence; strongly correlated electron; hole;

Online: 15 October 2020 (15:59:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202002.0099.v1

The Determination of HIV-1 RT Mutation Rate, Its Possible Allosteric Effects, and Its Implications on Drug Resistance

Joshua Yi Yeo, Ghin Ray Goh, Chinh Tran-To Su, Samuel Ken-En Gan

Subject: Biology And Life Sciences, Virology Keywords: retroviruses; HIV-1; reverse transcriptase; mutation rate; drug resistance, allostery

Online: 7 February 2020 (11:50:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202405.0002.v1

Alignment of Consumers’ Expected Brain Benefits from Food and Supplements with Measurable Cognitive Performance Tests

Hayley Anne Young, Alecia L Cousins, Carol Byrd-Bredbenner, David Benton, Richard Gershon, Alyssa Ghirardelli, Marie Latulippe, Andrew Scholey, Laura Wagstaff

Subject: Biology And Life Sciences, Food Science And Technology Keywords: consumer terminology; mood; cognitive health; brain health; nutrition; diet; supplements; validated tests

Online: 1 May 2024 (09:53:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201912.0074.v1

Application of Statistical Mirroring in ANOVA-Like Tests

Kabir Bindawa Abdullahi

Subject: Computer Science And Mathematics, Analysis Keywords: statistical mirroring; meanic mirror; comparative optinalysis; descriptive components; inferences

Online: 5 December 2019 (12:01:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints201811.0328.v1

Medi-Test: GENERATING Tests from Medical Reference Texts

Íonuț Pistol, Diana Trandabăț, Mădălina Răschip

Subject: Computer Science And Mathematics, Analysis Keywords: e-learning; automatic test generation; medical ontology; data mining for medical texts

Online: 14 November 2018 (09:45:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0559.v1

Optimization of RT-QuIC Assay Duration for Screening Chronic Wasting Disease in White-Tailed Deer

Gokhan Yilmaz, Tamara Morrill, Cian Ward, Gordon Mitchell, Andrei Soutyrine, Hanhong Dan, Min Lin, Jiewen Guan

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: RT-QuIC; Chronic Wasting Disease; Diagnostics; Optimization

Online: 7 September 2023 (15:45:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0618.v1

Functional Analysis of Genetic Tests in Neurological Diagnostics: Advances and Future Prospects

Richard Murdoch Montgomery

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Neurological diagnostics; Genetic technologies; Microarray analysis Variant sequencing; Exome sequencing; RNA sequencing; Whole genome sequencing; Functional analysis; Personalized medicine; Neurological disorders

Online: 9 September 2024 (09:21:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1054.v1

Characterization of antenna radiation pattern and penetration depth in GPR field tests

Pavel Morozov, Fedor Morozov, Maxim Lazarev, Leonid Bogolyubov, Alexei Popov

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: impulse subsurface radar, radiation pattern, archaeological and natural objects

Online: 15 May 2023 (14:33:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0172.v2

How Does Contrast Media Affect Cardiac Markers and Coagulation Tests? Experimental Study

Mustafa Begenc Tascanov, Ataman Gönel

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: contrast media; troponin; Nt-proBNP; interference

Online: 20 January 2019 (10:40:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1094.v1

Development and Evaluation of an In-House Real-Time Rt-Pcr Targeting nsp10 Gene for SARS-CoV-2 Detection

Cyril Chik-Yan Yip, Jane Hau-Ching Poon, Kit-Hang Leung, Wan-Mui Chan, Jonathan Daniel Ip, Allen Wing-Ho Chu, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Kelvin Kai-Wang To

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; COVID-19; nsp10; real-time RT-PCR; diagnostic

Online: 20 February 2024 (06:07:31 CET)

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Working Paper BRIEF REPORT

Positive Rate Is Useful to Evaluate the Sufficiency of RT-PCR Test Availability for COVID-19

Sadao Suzuki

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; RT-PCR test; pre-test probability; positive rate

Online: 5 May 2020 (06:04:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0413.v1

Comparison of Quantitative PCR (qPCR) Paenibacillus larvae Targeted Assays and Definition of Optimal Conditions for Its Detection/Quantification in Honey and Hive Debris

Franca Rossi, Carmela Amadoro, Addolorato Ruberto, Luciano Ricchiuti

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Paenibacillus larvae; optimized qPCR; quantification; honey; hive debris

Online: 20 September 2018 (14:13:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0381.v1

Building-Level Wastewater Monitoring for COVID-19 Using Tampon Swabs and RT-LAMP for Rapid SARS-Cov-2 RNA Detection

Aaron Bivins, Megan Lott, Marlee Shaffer, Zhenyu Wu, Devin North, Erin Lipp, Kyle Bibby

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: SARS-CoV-2; wastewater monitoring; environmental surveillance; RT-LAMP; building-level; near-source; passive sampling

Online: 17 May 2021 (10:07:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202101.0264.v1

Measuring Time-Varying Effective Reproduction (Rt) Numbers for COVID-19 and Their Relationship with Movement Control Order (MCO) in Malaysia

Musa Kamarul Imran, Wan Nor Ariffin, Mohd Mohd Hafiz, Subhi Jamiluddin, Noor Atinah Ahmad, Chen Xin Wee, Tengku Muhammad Hanis, Awang Bulgiba

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Reproduction number; COVID-19; movement control order; epidemic curve

Online: 14 January 2021 (09:41:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0896.v2

Spectral- and Image-Based Metrics for Evaluating Cleaning Tests on Unvarnished Painted Surfaces

Jan Dariusz Cutajar, Calin Constantin Steindal, Francesco Caruso, Edith Joseph, Tine Frøysaker

Subject: Arts And Humanities, Art Keywords: treatment evaluation; surface cleaning; soiling removal; agar gel; exposed grounds; unvarnished oil paints; Edvard Munch; spectral imaging

Online: 17 July 2024 (04:00:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0492.v2

Design, Modelling and Tests of a Barycenter Offset Locomotion Mechanism for Cylindrical Robots

Océane Patiny

Subject: Engineering, Automotive Engineering Keywords: Education Robotics; Mechanism Design; Motion Control; Barycenter Offset Robot

Online: 1 March 2022 (06:46:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0067.v1

Strategies for the Simulation of Sea Ice Organic Chemistry: Arctic Tests and Development

Scott Elliott, Nicole Jeffery, Elizabeth Hunke, Clara Deal, Meibing Jin, Shanlin Wang, Emma Elliott Smith, Samantha Oestreicher

Subject: Environmental And Earth Sciences, Geography Keywords: ice algae; brine channels; organic chemistry; Arctic sea ice; CICE model; mechanism development; biomacromolecules

Online: 12 April 2017 (05:12:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0463.v1

Development and Validation of a Combined RT-LAMP Assay for the Rapid and Sensitive Detection of Dengue Virus in Clinical Samples from Colombia

Katherine Escorcia-Lindo, Leidy Hurtado-Gómez, Juan Sebastian Rosero, Nataly Solano Llanos, Camilo Barrios Sánchez, Anderson Diaz Pérez, Yirys Díaz-Olmos, Jennifer García, Yesit Bello-Lemus, Leonardo C Pacheco-Londoño, Antonio J. Acosta-Hoyos, Lisandro A Pacheco-Lugo

Subject: Biology And Life Sciences, Life Sciences Keywords: RT-LAMP; Dengue virus (DENV); Sensitivity; Point-of-Care

Online: 5 September 2024 (12:37:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1000.v1

Measurement and Analysis of Brake and Tyre Particle Emissions from Automotive Series Components for High-Load Driving Tests on a Wheel and Suspension Test Bed

Martin Kupper, Ludwig Schubert, Manfred Nachtnebel, Hartmuth Schröttner, Michael Peter Huber, Peter Fischer, Alexande Bergmann

Subject: Environmental And Earth Sciences, Pollution Keywords: Non-Exhaust Emissions; Brake Wear Aerosol; Particle Measurement; Ultrafine Particles; Electron Microscopy

Online: 19 February 2024 (08:06:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.0425.v1

Impact of wind generation in the transformation centers of low voltage distribution networks using Opal-RT 5600

Javier Cabrera, Carlos Guerrero, Esteban Franco, Gabriela Araujo

Subject: Engineering, Electrical And Electronic Engineering Keywords: Wind energy; voltage profile; distribution network; simulation

Online: 6 June 2023 (09:35:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1579.v1

Performance of Rapid Diagnostic Tests for Malaria Diagnosis in Mali

Pascal Dembélé, Mady Cissoko, Adama Diarra, Lassina Doumbia, Maïssane Mehadji, Mahamadou Magassa, Aïssata Koné, Mahamadou Ali Thera, Stéphane Ranque

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Diagnostic; Paludisme; TDR; Sensibilité; Spécificité; RAP; Mali

Online: 26 November 2023 (06:19:51 CET)

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Preprint REVIEW | doi:10.20944/preprints202006.0278.v1

COVID-19 Serological Tests: How Well Do They Actually Perform?

Abdi Ghaffari, Robyn Meurant, Ali Ardakani

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: COVID-19; serological diagnostic test; performance evaluation

Online: 21 June 2020 (14:58:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0190.v1

Ranking of Normality Tests—An Appraisal through Skewed Alternative Space

Tanweer Islam

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: power envelope; Neyman-Pearson tests; Skewness & Kurtosis

Online: 15 May 2019 (10:50:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0220.v1

Selection and Multiplexing of Reverse Transcription Quantitative PCR Tests Targeting Relevant Honeybee Viral Pathogens

Franca Rossi, Ilaria Del Matto, Luciano Ricchiuti, Lucio Marino

Subject: Biology And Life Sciences, Life Sciences Keywords: ; honeybee; viral pathogens; RT-qPCR tests; TaqMan probes; duplex reactions ;

Online: 6 May 2024 (08:43:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1362.v1

Design and Initial Tests of a Fast Neutron Radiography Detector Prototype with Sipm Readout

Xu Chen, Bin Tang, Ruofu Chen, Zhifu Zhu, Pingchuan Zhang, Qian Yu, Chang Huang, Shaojia Chen, Xiuku Wang, Hong Xu, Xiaojie Cai, Dawei Guo, Li Yu, Zhijia Sun, Yanfeng Wang, Yuntao Liu

Subject: Physical Sciences, Radiation And Radiography Keywords: Neutron radiography; Monte-Carlo simulations; SiPM readout; EJ200 scintillator array; SiPMs array

Online: 21 April 2024 (05:21:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0956.v1

Machine Learning for Affordable Diagnosis of SARS-COV-2 from Hematological and Biochemical Tests

Reginaldo José da Silva, Carlos Roberto dos Santos Júnior, Thays Abreu, Carlos Roberto Minussi, Mara Lúcia Martins Lopes

Subject: Engineering, Electrical And Electronic Engineering Keywords: Adaptive Resonance Theory; Artificial Neural Networks; Blood tests; Coronavirus; COVID-19

Online: 15 April 2024 (11:57:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1590.v1

Digital Image Correlation Technique for Laboratory Structural Tests and Applications: A Systematic Literature Review

Mohammed Abbas Mousa, Mustafasanie M Yussof, Thulfiqar Hussein, Lateef Assi, SeyedAli Ghahari

Subject: Engineering, Civil Engineering Keywords: Keywords: Digital Image Correlation; Surface displacements; Structural monitoring; Full-scale test design

Online: 25 September 2023 (12:37:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0128.v1

Characterization and Thermal Aging Tests of Cr Based Multilayer for Unconcentrated Solar Thermal Applications

Antonio Caldarelli, Carmine D'Alessandro, Davide De Maio, Daniela De Luca, Eliana Gaudino, Marilena Musto, Emiliano Di Gennaro, Roberto Russo

Subject: Chemistry And Materials Science, Biomaterials Keywords: Spectrally selective coating; Optical properties; Thermal stability; High temperature emissivity; Energy activation; Prediction of lifetime test; Thermal aging.

Online: 6 July 2021 (09:29:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints202007.0465.v1

Preventing Laboratory-acquired Brucellosis in the Era of MALDI-TOF Technology and Molecular Tests

Pablo Yagupsky

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: laboratory-acquired brucellosis; prevention; biosafety; cultures; identification; biochemical tests; MALDI-TOF; FISH; laboratory-acquired brucellosis; prevention; biosafety; cultures; identification; biochemical tests; MALDI-TOF; FISH

Online: 20 July 2020 (09:38:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201910.0246.v1

Shearing with Infiltration Tests to Study Mechanical Behavior and Failure Mechanism of Shallow Slopes

Ali Murtaza Rasool, Jiro Kuwano

Subject: Engineering, Civil Engineering Keywords: shallow slopes; unsaturated soil; slope stability; deviatoric stress; pore-water pressure; water infiltration

Online: 21 October 2019 (15:22:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1366.v1

Cycle Threshold Values of SARS-CoV-2 RT-PCR During Outbreaks in Nursing Homes: A Retrospective Cohort Study.

Juan Carlos Gasco-Laborda, Maria Gil-Fortuño, Maria Dolores Tirado-Balaguer, Noemi Meseguer-Ferrer, Oihana Sabalza-Baztán, Óscar Pérez-Olaso, Iris Gómez-Alfaro, Sandrine Poujois-Gisbert, Noelia Hernández-Pérez, LLedó Lluch-Bacas, Viorica Rusen, Alberto Arnedo-Pena, Juan Bautista Bellido-Blasco

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: SARS-CoV-2; PCR; cycle threshold; infections; nursing homes; outbreaks; retrospective cohort

Online: 18 September 2024 (11:47:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.1196.v1

Effect of Accelerated Aging Tests in Salt Spray of Single Lap Friction Stir Welded Joints between S355-J0 Steel – AA5083 Aluminum Alloy. – Part 1 – Mechanical Tests

Borsellino Chiara, Federica Favaloro, Guido Di Bella

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: joining; FSW; shipbuilding; aluminum; steel; aging tests; salt spay

Online: 15 December 2023 (18:56:57 CET)

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Working Paper ARTICLE

Detection of Multiple Transgene Fragments in a Mouse Model of Gene Doping Based on Plasmid Vector Using TaqMan-qPCR Assay

Takeito Sugasawa, Kai Aoki, Koki Yanazawa, Kazuhiro Takekoshi

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: gene doping; gene therapy; in vivo transfection; in vivo imaging

Online: 3 June 2020 (05:46:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0426.v1

Research on Specific Scenario Generation Methods for Autonomous Driving Simulation Tests

Ning Li, Lingshan Chen, Yongchao Huang

Subject: Engineering, Automotive Engineering Keywords: automated driving virtual simulation; subjective empowerment; objective empowerment; combined testing; test case generation

Online: 7 November 2023 (09:30:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1816.v1

Kernel-Based Independence Tests for Causal Structure Learning on Functional Data

Felix Laumann, Julius Von Kügelgen, Junhyung Park, Bernhard Schölkopf, Mauricio Barahona

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: causal discovery; independence tests; functional data analysis; kernel methods

Online: 30 October 2023 (04:50:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202209.0003.v1

Evaluation of Toxic Gas Generation, Smoke Generation, and Flammability in Flame-Retardant Plywood Combustion Tests

Hee-Jun PARK, Seok-Un JO

Subject: Chemistry And Materials Science, Other Keywords: flame-retardant plywood; flammability; toxic gas generation; smoke generation

Online: 1 September 2022 (03:50:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1994.v1

A Colorimetric RT-LAMP Detection of Multiple SARS-CoV-2 Variants of Concern and Lineages from Direct Nasopharyngeal Swab Samples without RNA Isolation

Santiago Enrique Werbajh, Luciana Larocca, Carolina Carrillo, Fabiana Stolowicz, Lorena Ogas, Sergio Pallotto, Solange Cassará, Lilia Mammana, Inés Zapiola, María Belén Bouzas, Adrián Alberto Vojnov

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; SARS-CoV-2; LAMP

Online: 28 July 2023 (13:29:56 CEST)

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Preprint REVIEW | doi:10.20944/preprints202105.0552.v1

Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential Pathogenesis

Donovan A. McGrowder, Fabian Miller, Melisa Anderson Cross, Lennox Anderson-Jackson, Sophia Bryan, Lowell Dilworth

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Liver; biochemistry tests; function; COVID-19; injury; SARS-CoV-2; infection; severity; mortality

Online: 24 May 2021 (10:14:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1147.v1

Pseudo-Dynamic Tests on Frame-Shear Wall Structure with Precast Concrete Diaphragm

Chun Han, Xinhong Dong, Qunshan Su, Chunming Duan, Guoping Tian

Subject: Engineering, Civil Engineering Keywords: Frame-shear wall structure; Precast concrete; Floor diaphragms; Pseudo-dynamic test; Seismic behavior

Online: 19 March 2024 (12:39:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0661.v1

New Goodness-of-Fit Tests for the Kumaraswamy Distribution: A Simulation Study

David E. Giles

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: goodness-of-fit testing; empirical distribution function; Kumaraswamy distribution

Online: 11 March 2024 (18:09:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.2186.v1

Laboratory Tests Might Mitigate Misdiagnosis of Child Abuse Established on Clinical Grounds

Sergio Verd, Elisa Lizarbe, Elena Sol, Alicia-Esther Tur

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Child abuse; Child growth; Child custody; Oxidative stress; Aspartate aminotransferase; Fatty liver; Insulin resistance

Online: 31 January 2024 (12:54:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1629.v1

Comparison of Multiple Carbapenemase Tests Based on an Unbiased Colony Selection Method

Hsin-Yao Wang, Yi-Ju Tseng, Wan-Ying Lin, Yu-Chiang Wang, Ting-Wei Lin, Jen-Fu Hsu, Marie Yung-Chen Wu, Chiu-Hsiang Wu, Sriram Kalpana, Jang-Jih Lu

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: carbapenemase; unbiased colony selection; mCIM/eCIM; Carba5; CPO panel

Online: 21 December 2023 (10:27:01 CET)

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Preprint REVIEW | doi:10.20944/preprints201912.0002.v1

Point-of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Mini-Review

Michelle A. Bulterys, Bradley Wagner, Maël Redard-Jacot, Anita Suresh, Nira R. Pollock, Emmanuel Moreau, Claudia M. Denkinger, Paul K. Drain, Tobias Broger

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: tuberculosis (TB); diagnostics; lipoarabinomannan (LAM); urinary test; diagnosis

Online: 2 December 2019 (04:18:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0132.v1

Case-Based Study of Metrics Derived from Instrumented Fall Risk Assessment Tests

Anabela Martins, Joana Silva, António Santos, João Madureira, Carlos Alcobia, Luís Ferreira, Pedro Mendes, Cláudia Tonelo, Catarina Silva, Daniela Baltazar, Inês Sousa

Subject: Medicine And Pharmacology, Other Keywords: fall risk assessment; risk of falling; force platforms; inertial sensors.

Online: 12 August 2016 (09:32:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1516.v1

Modelling CO2 Emissions from Vehicles Fuelled with CNG Based on On-Road and Chassis Dynamometer Tests

Maksymilian Mądziel

Subject: Engineering, Transportation Science And Technology Keywords: vehicles; CNG; emission; PEMS; chassis dynamometer; pollution

Online: 26 March 2024 (11:59:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0269.v1

Exposure to Forest Air Monoterpenes and Pulmonary Function Tests in Adolescents With Asthma: A Cohort Study

Davide Donelli, Michele Antonelli, Rita Baraldi, Anna Corli, Franco Finelli, Federica Gardini, Giovanni Margheritini, Francesco Meneguzzo, Luisa Neri, Davide Lazzeroni, Diego Ardissino, Giorgio Piacentini, Federica Zabini, Annalisa Cogo

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Asthma; Forest atmosphere; Monoterpenes; Respiratory functions; Volatile organic compounds.

Online: 5 September 2023 (08:02:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0664.v1

Validity and Reproducibility of Various Linear Sweep Voltammetry Tests of Anode and Cathode Electrodes in Microbial Electrolysis Cells

Hyungwon Chai, Bonyoung Koo, Sunghoon Son, Sokhee P. Jung

Subject: Engineering, Electrical And Electronic Engineering Keywords: Microbial electrolysis cells; Linear sweep voltammetry; Counter electrode; Coefficient of variation; Reproducibility

Online: 30 August 2020 (11:45:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints202009.0654.v1

BARD1 and Breast Cancer: The Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women

Marcin Śniadecki, Michał Brzeziński, Katarzyna Darecka, Dagmara Klasa-Mazurkiewicz, Patryk Poniewierza, Marta Krzeszowiec, Natalia Kmieć, Dariusz Wydra

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: breast cancer; BARD1; surveillance; management; genetic testing; predisposition; susceptibility; neoadjuvant; chemotherapy

Online: 26 September 2020 (17:32:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202008.0371.v1

BARD1 and Breast Cancer: the Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women

Marcin Śniadecki, Michał Brzeziński, Katarzyna Darecka, Dagmara Klasa-Mazurkiewicz, Patryk Poniewierza, Marta Krzeszowiec, Natalia Kmieć, Dariusz Wydra

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: breast cancer; BARD1; surveillance; management; genetic testing; predisposition; susceptibility; neoadjuvant; chemotherapy

Online: 18 August 2020 (03:08:11 CEST)

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