Search Results
32173 articles found
REVIEW
|
doi:10.20944/preprints202402.0637.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
TPD; PROTAC; molecular glue degrader; heterobifunctional degrader; Ubiquitin; proteasome; targeted protein degradation
Online: 12 February 2024 (07:43:06 CET)
REVIEW
|
doi:10.20944/preprints202209.0320.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
marine natural products; oxygen heterocycles; tetrahydrofuran; total synthesis; biological activity; terpenes; fatty acids.
Online: 21 September 2022 (10:04:09 CEST)
REVIEW
|
doi:10.20944/preprints202207.0130.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Keywords: mitochondria; stress resilience; plasticity; stress; kynurenine; Alzheimer’s disease; neurodegenerative; depression; anxiety; psychiatric
Online: 8 July 2022 (03:56:36 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1884.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Natural products; Molecular Docking, Antiviral Activity; SARS-CoV-2; Cell Proliferation Inhibition
Online: 1 April 2024 (11:54:06 CEST)
ARTICLE
|
doi:10.20944/preprints201703.0155.v1
Subject:
Chemistry And Materials Science,
Other
Keywords:
molecularly imprinted polymers; solid-phase extraction; oblongifolin C; guttiferone K; Garcinia yunnanensis Hu
Online: 20 March 2017 (09:38:35 CET)
REVIEW
|
doi:10.20944/preprints202404.0055.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Lead optimization; drug discovery; artificial intelligence; machine learning; deep neural networks; cheminformatics; chemical modifications; drug development
Online: 1 April 2024 (13:35:22 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0062.v1
Subject:
Computer Science And Mathematics,
Computer Vision And Graphics
Keywords:
graph neural network; motif-based representation; molecular property prediction; graph matching; interpretability; GPU-enabled accelerating.
Online: 5 December 2022 (06:57:41 CET)
ARTICLE
|
doi:10.20944/preprints202402.0943.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
degradation monitoring; health monitoring; causal discovery; jaccard distance, inter- 14 pretability; causal interpretability
Online: 19 February 2024 (10:09:53 CET)
ARTICLE
|
doi:10.20944/preprints202404.1167.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Wilms’ tumor; Chemotherapy resistance; Biomarkers; Somatic mutation; Targeted therapy; Cancer-driver mutation
Online: 17 April 2024 (15:03:01 CEST)
ARTICLE
|
doi:10.20944/preprints201609.0123.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
carbonic anhydrase; acetylcholinesterase; β-Lactam; 2-Azetidinone; enzyme inhibition; enzyme purification
Online: 30 September 2016 (05:38:45 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1117.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
globospiramine; bisindole alkaloid; Voacanga globosa; Candida albicans; Candida tropicalis; molecular docking; molecular dynamics; antifungal; apoptosis
Online: 17 April 2024 (08:30:56 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
SARS-CoV; PBM; envelope protein; LUAD; bioinformatics
Online: 12 March 2020 (09:28:43 CET)
ARTICLE
|
doi:10.20944/preprints202402.0681.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
early-stage breast cancer; circulating tumor cells; rare cells, liquid biopsy; systemic cancer; cytomorphology
Online: 12 February 2024 (11:37:36 CET)
REVIEW
|
doi:10.20944/preprints202310.1465.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
drug discovery; target identification; target validation; lead identification; bioinformatics
Online: 24 October 2023 (04:09:01 CEST)
CONCEPT PAPER
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Salmonella enterica; food safety; genome; theory; single nucleotide polymorphisms; recombination; serotype
Online: 31 August 2021 (12:47:33 CEST)
REVIEW
|
doi:10.20944/preprints202202.0067.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Antimalarial Drug; Malaria Vaccine; Drug Discovery; Artimisnine; K13; Malaria
Online: 4 February 2022 (10:22:34 CET)
REVIEW
|
doi:10.20944/preprints202405.0668.v3
Subject:
Neuroscience And Neurology,
Biology And Life Sciences
Keywords:
epilepsy; neuroinflammation; NLRP3 inflammasome; epileptogenesis; antiseizure medication; interleukin-1b; caspase-1; ASC
Online: 31 May 2024 (15:29:49 CEST)
REVIEW
|
doi:10.20944/preprints202305.0625.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Saccharomyces cerevisiae; Ethanol biosynthesis; Material metabolism
Online: 9 May 2023 (09:32:11 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0093.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
SARS-CoV-2; variants; spike glycoprotein; receptor binding motif; receptor binding domain; neutralizing antibodies; Ig subclasses; IgG; IgA
Online: 2 February 2024 (07:31:35 CET)
ARTICLE
|
doi:10.20944/preprints202003.0046.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
AT-hook motif nuclear protein 18; AHL18; At3G60870; Arabidopsis; Lateral root development; Root apical meristem; Cell proliferation
Online: 4 March 2020 (04:40:34 CET)
ARTICLE
|
doi:10.20944/preprints202404.0701.v1
Subject:
Engineering,
Other
Keywords:
automated cloud management; application discovert; log analytics; recommender systems
Online: 10 April 2024 (10:02:11 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1267.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
new hepadnaviruses; hepatitis B virus; animal model; HBV cure; viral infection; metagenomics; next-generation sequencing (NGS)
Online: 21 November 2023 (09:59:58 CET)
ARTICLE
|
doi:10.20944/preprints202306.2033.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Process Mining; Process Model Discovery; Mining action+state evolution
Online: 28 June 2023 (16:19:00 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
natural products; biosynthetic gene clusters; synthetic biology; genome mining strategies; modification strategies; design-build-test-learn (DBTL) cycle
Online: 8 October 2021 (09:10:02 CEST)
ARTICLE
|
doi:10.20944/preprints201801.0106.v2
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
catalytide; serine protease-like peptide; Tob1
Online: 17 January 2018 (07:27:30 CET)
ARTICLE
|
doi:10.20944/preprints202311.0296.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
SARS-CoV-2; Variants; Spike Glycoprotein; Receptor Binding Motif, Receptor Binding Domain; Neutralizing Antibodies; Ig subclasses; IgG; IgA
Online: 7 November 2023 (11:27:48 CET)
REVIEW
|
doi:10.20944/preprints202406.0927.v2
Subject:
Biochemistry And Molecular Biology,
Biology And Life Sciences
Keywords:
phytochemicals; natural products; traditional medicine
Online: 17 June 2024 (10:52:10 CEST)
REVIEW
|
doi:10.20944/preprints202311.0852.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Computer-Aided Drug Design (CADD); Machine Learning and Artificial Intelligence (AI); Drug discovery; Chemoinformatics; Molecular modeling; Molecular Docking; Target identification
Online: 14 November 2023 (16:54:42 CET)
REVIEW
|
doi:10.20944/preprints202311.1314.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
cell penetrating peptides; protein transduction domains; cardiac targeting peptide; heart failure; atrial fibrillation
Online: 21 November 2023 (10:43:05 CET)
REVIEW
|
doi:10.20944/preprints202306.0141.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Mycobacterium tuberculosis; target identification; activity-based probes; affinity-based probes
Online: 2 June 2023 (07:39:37 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0199.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
KCNQ1; Kv7.1; IKs; patch-clamp; inherited channelopathy; LQTS
Online: 14 June 2022 (08:42:22 CEST)
REVIEW
|
doi:10.20944/preprints202106.0023.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
cancer; cardiovascular disease; chemokine (C-C motif) ligand 2; fatty liver; infection; inflammation; metabolism; obesity; paraoxonase-1
Online: 1 June 2021 (10:46:20 CEST)
REVIEW
|
doi:10.20944/preprints202210.0148.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug development; high throughput screening; in vivo/in silico screening; zebrafish
Online: 11 October 2022 (10:33:33 CEST)
REVIEW
|
doi:10.20944/preprints202012.0554.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
microbiome; vectorial capacity; density; competence; biting; extrinsic incubation period; longevity; mosquito; symbiosis; pathogen transmission
Online: 22 December 2020 (10:49:13 CET)
REVIEW
|
doi:10.20944/preprints202311.1361.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
induced pluripotent stem cells; disease modeling, neurodegenerative diseases
Online: 22 November 2023 (09:39:09 CET)
REVIEW
|
doi:10.20944/preprints202305.0945.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Systems Pharmacology; Polypharmacology; Adverse Events; Drug Discovery; Functional genomics; Disease Modeling; Network analysis; Innovation
Online: 12 May 2023 (12:18:59 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0383.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
meprin α; meprin β; zinc metalloproteinase; medicinal chemistry; probe development
Online: 15 December 2020 (12:56:31 CET)
ARTICLE
|
doi:10.20944/preprints202012.0354.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
meprin α; meprin β; zinc metalloproteinase; uHTS
Online: 14 December 2020 (16:36:57 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202011.0250.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
antibiotic discovery; STEM education; biosynthetic gene cluster; molecular networking; multi-omics
Online: 6 November 2020 (16:50:46 CET)
REVIEW
|
doi:10.20944/preprints201910.0144.v6
Subject:
Biology And Life Sciences,
Virology
Keywords:
virus; antiviral drug; drug discovery; drug development; broad-spectrum antivirals
Online: 14 February 2020 (02:27:24 CET)
ARTICLE
Subject:
Environmental And Earth Sciences,
Paleontology
Keywords:
islands, discovery, settlement, colonization, Easter Island, Rapa Nui, Pacific Ocean, Polynesians, Amerindians
Online: 28 March 2019 (11:22:33 CET)
ARTICLE
|
doi:10.20944/preprints202109.0257.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
protein-protein interactions; PDZ domains; choanoflagellates; evolution; target selectivity; protein-peptide interactions; signaling
Online: 15 September 2021 (12:25:01 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0255.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
bony fish muscle, insect flight muscle, myosin filament structure, myosin crossbridge cycle, thick filament activation, interacting heads motif
Online: 23 July 2019 (10:57:56 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1882.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
fSP3; drug design; bioavailability; non-systemic drugs; druglikeness; cheminformatics
Online: 29 August 2023 (03:25:53 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0145.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
electroencephalography (EEG); EEG bands; decision tree; machine learning
Online: 10 March 2022 (10:38:44 CET)
REVIEW
|
doi:10.20944/preprints201902.0209.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ebolavirus; Filoviridae; VSV; retroviral vectors; virus like particles; pseudovirus; antivirals; small molecules; viral entry.
Online: 21 February 2019 (13:13:34 CET)
ARTICLE
|
doi:10.20944/preprints201809.0587.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
machine learning; conotoxins; cone snails; venom; drug discovery
Online: 29 September 2018 (07:39:42 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0339.v1
Subject:
Arts And Humanities,
Film, Radio And Television
Keywords:
National Cinema; Transnational Japanese Film; taiyōzoku; mukokuseki; ’kimono effect’; youth icons; postwar film festivals.
Online: 18 September 2018 (09:49:29 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1262.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Avian metapneumovirus subgroup C; fusion protein; integrin β1; viral entry; avian and human cells
Online: 18 December 2023 (10:19:05 CET)
ARTICLE
|
doi:10.20944/preprints201809.0216.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
optogenetics; channelrhodopsin2; subcellular targeting; potassium channel Kv2.1; mislocalization
Online: 12 September 2018 (10:51:10 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0415.v2
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Psychological Health; Drugs; Twitter; Machine Learning; Big Data; Drug Abuse; Toxicology; Social Factors; Economic Factors; Environmental Factors
Online: 27 February 2023 (13:31:40 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
XPAzf; Zn; Cd; GSNO; H2O2; oxidation
Online: 24 August 2020 (09:50:12 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2120.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Trypanosoma cruzi; genome sequencing; reverse genetics; drug efficacy testing
Online: 31 August 2023 (04:19:55 CEST)
REVIEW
|
doi:10.20944/preprints202206.0193.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
aminosugar; antibiotic; biosynthesis; glycosylation; lemonomycin; total synthesis
Online: 14 June 2022 (04:55:21 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0218.v1
Subject:
Business, Economics And Management,
Econometrics And Statistics
Keywords:
agricultural commodity futures; price discovery; market reflexivity; Hawkes process
Online: 13 May 2020 (03:35:53 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0415.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
triple-negative breast cancer; dexmedetomidine; IDO1; CHRM3
Online: 7 February 2024 (08:18:40 CET)
ARTICLE
|
doi:10.20944/preprints202104.0270.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Systemic amyloidosis; amyloid fibrils; amyloidogenesis inhibitors; antibody light chains; light chain stabilizers; doxycycline; EGCG; thioflavin T; filter trap; PAINS
Online: 9 April 2021 (15:07:24 CEST)
REVIEW
|
doi:10.20944/preprints202102.0405.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
drug repurposing; antifungal therapy; antifungal mechanism; clinical application; antifungal agents
Online: 18 February 2021 (10:21:38 CET)
REVIEW
|
doi:10.20944/preprints201908.0271.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GPCRs; membrane protein; molecular dynamics; protein structure; drug design; biased-signaling pathway; allosteric sites
Online: 26 August 2019 (15:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0100.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer biomarker discovery; gene expression data; Ingenuity Knowledge Base (IKB); transfer learning; interpretable classification rules
Online: 8 August 2019 (05:28:26 CEST)
REVIEW
|
doi:10.20944/preprints202105.0346.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
drug discovery; drug repurposing; bioinformatics; machine learning; artificial intelligence; biomedical discoveries etc.
Online: 14 May 2021 (15:17:50 CEST)
Subject:
Environmental And Earth Sciences,
Paleontology
Keywords:
Pyrenees; paleoecology; hypothesis testing; discovery; serendipity; Quaternary; Lateglacial; Holocene; last millennia
Online: 10 May 2023 (08:24:15 CEST)
REVIEW
|
doi:10.20944/preprints202201.0050.v1
Subject:
Engineering,
Mechanical Engineering
Keywords:
turbulence; flow control; simulation; aerodynamics; machine learning; deep reinforcement learning
Online: 6 January 2022 (09:36:50 CET)
REVIEW
|
doi:10.20944/preprints202010.0179.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non Michaelis-Menten Kinetics; High-throughput screening; allostery; cooperativity; processive kinetics; distributive kinetics; single-molecule; auto-catalytic; drug discovery
Online: 8 October 2020 (13:34:16 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0453.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Michael acceptor; safe covalent drugs; oxidative stress inducers; trans-cinnamaldehyde; curcumin; colorectal cancer
Online: 29 February 2020 (04:22:03 CET)
ARTICLE
|
doi:10.20944/preprints202107.0142.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Arabidopsis thaliana; indole-3-acetic acid; jasmonic acid; plant hormone crosstalk; transcriptional regulation; wound response; biotic stress; growth-defense trade-off
Online: 6 July 2021 (12:20:15 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0223.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Genome packaging ATPase; vaccinia virus; coiled coil motif; FtsK/HerA superfamily; Nucleo-cytoplasmic large DNA viruses
Online: 5 February 2024 (07:48:18 CET)
ARTICLE
|
doi:10.20944/preprints202307.0482.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cardiac arrhythmia; atrial fibrillation; medical genetics; molecular biology; linkage analysis; transcriptional regulation; TBX20; biological assay
Online: 7 July 2023 (10:53:05 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1211.v1
Subject:
Computer Science And Mathematics,
Data Structures, Algorithms And Complexity
Keywords:
attention deficit/hyperactivity disorder; attentional variability; network communities; deficit hyperactivity disorder spectrum
Online: 16 June 2023 (10:15:45 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0908.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Deep Learning; Topic Discovery; Latent Dirichlet Allocation; Latent Semantic Analysis; Probabilistic Latent Semantic Analysis
Online: 12 May 2023 (08:52:57 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0224.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; drug discovery; multitargeting; computational drug repurposing
Online: 26 April 2022 (03:39:06 CEST)
REVIEW
|
doi:10.20944/preprints202312.1256.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Biobanking; human biospecimens; drug discovery; health research
Online: 18 December 2023 (10:33:49 CET)
REVIEW
|
doi:10.20944/preprints202311.1051.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Toxoplasma gondii; proteomics; host-parasite interactions; PTMs; drug discovery
Online: 16 November 2023 (07:46:09 CET)
ARTICLE
|
doi:10.20944/preprints202302.0066.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Smart Tourism; Sustainable Tourism; Natural language Processing (NLP); Big Data Analytics; Deep Learning; Machine Learning; Unsupervised Learning; Bidirectional Encoder Representations from Transformers (BERT); Literature Review; Smart Societies
Online: 3 February 2023 (09:47:55 CET)
COMMUNICATION
|
doi:10.20944/preprints202209.0147.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Myxochelin; Myxobacteria; Biosynthesis; Natural Products; Secondary Metabolites; Succinylation; Siderophore; Succinyl-coenzyme A
Online: 12 September 2022 (12:22:43 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0063.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
FABP4; A-FABP; aP2; antidiabetes; antiobesity; antiatherosclerosis; anticancer; computational tools; computer-aided drug discovery
Online: 5 September 2019 (15:39:58 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0322.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Viral Ecology; APMV; wild birds; Surveillance of Avian Paramyxoviruses; phylogenetics; MinION; Azov-Black Sea region in Ukraine
Online: 23 June 2022 (09:33:18 CEST)
REVIEW
|
doi:10.20944/preprints202401.1595.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Alzheimer’s disease; biomarker; proteomics; cerebrospinal fluid; Aβ protein; neurofibril- 14 lary tangles; plasma
Online: 22 January 2024 (14:08:41 CET)
REVIEW
|
doi:10.20944/preprints202309.1753.v1
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
Josephson junction arrays; topological field theory; topological phases of matter; superinsulators
Online: 26 September 2023 (08:24:44 CEST)
REVIEW
|
doi:10.20944/preprints202305.0473.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Drug Discovery; Drug Design; Drug Development, Quantum Computing, Quantum Machine Learning
Online: 8 May 2023 (08:37:23 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0971.v1
Subject:
Virology,
Biology And Life Sciences
Keywords:
virus detection; next-generation sequencing; bioinformatics analysis; SNP discovery; viral genomics; AI-assisted genomics
Online: 14 May 2024 (13:26:57 CEST)
REVIEW
|
doi:10.20944/preprints202306.1426.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Trypanosomatids; squalene synthase; farnesyl diphosphate synthase; target-based approach; neglected tropical diseases.
Online: 20 June 2023 (10:27:48 CEST)
ARTICLE
|
doi:10.20944/preprints202210.0242.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
pheromones; androstenone; mouse deer; metabolic pathway; reproduction; hormones
Online: 18 October 2022 (02:44:00 CEST)
REVIEW
|
doi:10.20944/preprints202304.0677.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
Metabolomics; Simultaneous Quantitation and Discovery (SQUAD); Targeted Metabolomics; Untargeted Metabolomics
Online: 21 April 2023 (07:29:13 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0447.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
SARS-CoV-2; ACE2; RGD; Spike protein; therapeutic drugs
Online: 28 February 2020 (16:26:53 CET)
BRIEF REPORT
|
doi:10.20944/preprints202007.0488.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV; SARS-CoV; COVID-19; Sarbecovirus; D614G; Spike glycoprotein; Coronavirus; Alignment-free
Online: 21 July 2020 (12:47:13 CEST)
REVIEW
|
doi:10.20944/preprints202405.1011.v1
Subject:
Biophysics,
Biology And Life Sciences
Keywords:
membrane electricity; excitability; action potential; ion channels
Online: 15 May 2024 (07:35:21 CEST)
ARTICLE
|
doi:10.20944/preprints202312.0813.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Genome-wide association studies; Alzheimer's disease; Deep Learning; neural networks
Online: 12 December 2023 (07:36:46 CET)
REVIEW
|
doi:10.20944/preprints202311.0144.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Early diagnosis; lung cancer; biomarkers; body fluids; research management
Online: 2 November 2023 (09:32:59 CET)
REVIEW
|
doi:10.20944/preprints202208.0213.v2
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GIBAC; Biophysics; Structural Biology; Drug discovery \& design; Artificial intelligence-integrated drug discovery
Online: 19 October 2023 (13:38:05 CEST)
COMMUNICATION
|
doi:10.20944/preprints202308.2067.v1
Subject:
Environmental And Earth Sciences,
Geochemistry And Petrology
Keywords:
mafic granulites; Tianshan; Muzhaerte; high-temperature metamorphism; geothermobarometry
Online: 30 August 2023 (14:11:45 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1966.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
Drug discovery; computational chemistry; conceptual DFT; marine cyclopeptides; chemical reactivity properties; bioavailability scores
Online: 29 August 2023 (09:36:49 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0670.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
melanoma; biomarker; transfer learning; ensemble model; bias; machine learning
Online: 27 May 2021 (13:20:55 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0213.v1
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
Clustering; Pattern Discovery; Time series; Multi-Level Spectral Clustering; English Channel
Online: 8 August 2020 (18:00:26 CEST)
CASE REPORT
|
doi:10.20944/preprints202405.0748.v1
Subject:
Library And Information Sciences,
Social Sciences
Keywords:
FAIR Principles; Open Science; Social Sciences and Humanities (SSH); Information and Data Management Systems; Discovery Platforms for SSH Research; OPERAS Services
Online: 13 May 2024 (08:04:58 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0566.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Barcoding; whole genome sequencing; polyketides; antimicrobial resistance; denitrification
Online: 8 April 2024 (15:06:32 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0457.v1
Subject:
Medicine And Pharmacology,
Veterinary Medicine
Keywords:
Newcastle disease virus; natural compounds; antiviral drugs; NDV; MD simulation; Hemagglutinin Neuraminidase; biological activity; ADMET; pharmacophore; screening
Online: 8 March 2024 (03:56:28 CET)
ARTICLE
|
doi:10.20944/preprints202311.0616.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Transfer factor; Natural Killer cells; plant proteins; immune support; Brassica juncea; Raphanus sativus
Online: 9 November 2023 (08:45:42 CET)
ARTICLE
|
doi:10.20944/preprints202310.0425.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
hepatitis B; antiviral; drug discovery; HBc protein; pharmacophore-based screening; drug repurposing
Online: 8 October 2023 (05:11:37 CEST)
ARTICLE
|
doi:10.20944/preprints201703.0215.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
FGFR1; inhibitor; kinase inhibitor; pyrazine; hinge binder
Online: 30 March 2017 (04:13:45 CEST)