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Preprint ARTICLE | doi:10.20944/preprints202203.0234.v1

Demographic Variables Impact on Individual Investment Return

Md. Fazlul Huq Khan, Fakrul Ahmed

Subject: Business, Economics And Management, Finance Keywords: Stock Market; Individual return; Bangladesh

Online: 16 March 2022 (14:26:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.2130.v1

Emergency Animal Boarding: A Social Return on Investment

Gemma Catherine Ma, Jioji Ravulo, Ursula McGeown

Subject: Social Sciences, Other Keywords: Companion animal; dog; cat; human-animal bond; Social Return on Investment; animal shelter; animal welfare

Online: 30 May 2023 (11:34:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1191.v1

Systematic Review of Machine Learning Return-on-Investment Forecasting

Nancy Chen

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Machine Learning; Latent Semantic Analysis; Gradient Boosting; Random Forest; Logistic Regression

Online: 16 July 2024 (05:34:01 CEST)

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Preprint ESSAY | doi:10.20944/preprints202404.0034.v1

How to Become a Terran. Return to Earth as Geo-Gastro-Politics

Harald Lemke

Subject: Arts And Humanities, Philosophy Keywords: gastroethics; gastrosophy; Slow Food movement; humification; the terrestrial party; everyday activism

Online: 1 April 2024 (11:12:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1887.v1

The Impact of Intellectual Capital on Sustainable Performance: Banking Sector in Saudi Arabia

Omer Ahmed Sayed, Aida Nefzi

Subject: Business, Economics And Management, Economics Keywords: Intellectual Capital; Sustainable Performance; Saudi Arabian Banks; Human Capital Efficiency; Structural Capital Efficiency; Capital Employed Efficiency

Online: 29 April 2024 (05:12:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0291.v1

The Relationship between Entrepreneurship and Sustainable Development in Saudi Arabia: A Comprehensive Perspective

Lena Bedawi Elfadli Elmonshid, Omer Ahmed Sayed

Subject: Business, Economics And Management, Economics Keywords: Entrepreneurship; Sustainable Development; Economic Growth; Environmental Sustainability; ARDL Model

Online: 3 July 2024 (06:36:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0911.v1

Digital Transformation, Absorptive Capacity and Enterprise Esg Performance: A Case Study of Strategic Emerging Industries

Wenjun Li, Mu Zhang

Subject: Business, Economics And Management, Other Keywords: Digital Transformation; Absorption Capacity; Enterprise ESG Performance; Strategic Emerging Industries; Regional Digitalization Level

Online: 14 May 2024 (06:50:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0184.v1

Perspectives on Adversarial Classification

David Rios Insua, Roi Naveiro, Victor Gallego

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Classification; Adversarial Machine Learning; Security; Robustness; Adversarial Risk Analysis

Online: 8 September 2020 (10:25:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1192.v1

Does Debt Structure Explain the Relationship between Agency Cost of Free Cash Flow and Dividend Payment? Evidence from Saudi Arabia

MOEZ DABBOUSSI

Subject: Business, Economics And Management, Finance Keywords: Debt Structure; Agency Cost of Free Cash Flow; Dividend Payment; Panel Data Analysis

Online: 18 April 2024 (13:45:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0862.v1

Intellectual Capital and Bank Stability in Saudi Arabia: Navi-gating the Dynamics in a Transforming Economy

Faiza Omer Elmahgop

Subject: Business, Economics And Management, Finance Keywords: Intellectual Capital; Bank stability; Human Capital Efficiency; Structural Capital Efficiency; Capital Employed Efficiency; Leverage; Operating efficiency

Online: 12 April 2024 (15:45:47 CEST)

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Preprint ESSAY | doi:10.20944/preprints202307.1330.v1

Research on E-commerce Platform’s Return Strategies Considering Consumer Abusing Return Policies

Huixin Liu, Feng Du

Subject: Business, Economics And Management, Business And Management Keywords: abuse of return policy; network effect; return policy; platform operation strategy

Online: 19 July 2023 (10:11:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1722.v1

Economic Reforms and Consumption Trends: A Deep Dive into Saudi Arabia's Economic Evolution

Mwahib Mohammed

Subject: Business, Economics And Management, Economics Keywords: ; aggregate consumption; government spending; oil revenues; interest rates Saudi Arabia

Online: 22 July 2024 (12:26:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0171.v1

Influencer Marketing ROI: Measurement Techniques and Optimization Strategies

Chris Bell, Ayoolu Olukemi, Peter Broklyn

Subject: Business, Economics And Management, Marketing Keywords: Influencer Marketing ROI; Measurement Techniques; Optimization Strategies

Online: 2 August 2024 (11:33:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1755.v1

Analyzing GDP Growth Drivers in Saudi Arabia: Investment or Consumption: An Evidence-Based ARDL Bound Test Approach

Mwahib Mohammed Gasmelsied Ahmed

Subject: Business, Economics And Management, Economics Keywords: Gross Domestic Product (GDP), Consumption, Investment, Saudi Arabia

Online: 29 February 2024 (16:59:00 CET)

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Preprint REVIEW | doi:10.20944/preprints202404.0987.v1

An Overview on Capital Investment

Sibi Mathew

Subject: Arts And Humanities, Other Keywords: Investment; cost analysis; investment decision; investment budgeting

Online: 15 April 2024 (14:57:49 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.2031.v1

Exploring the Dark Matter of Human Proteome: Emerging Role of Non-canonical Open Reading Frame (ncORF) in Cancer Diagnosis, Biology, and Therapy

Anni Ge, Curtis Chan, Xiaolong Yang

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: human proteome; ncORF; micropeptide; microprotein; cancer biology, therapy

Online: 28 June 2024 (13:48:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0611.v1

Derangetropy in Probability Distributions and Information Dynamics

Masoud Ataei, Xiaogang Wang

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Information Dynamics; Probability Distributions; Functional Measures; Entropy; Combinatorial Analysis; Differential Equations; Information Theory; Equilibrium Analysis

Online: 9 September 2024 (08:43:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1865.v1

Impacts of the Transition to the Expected Loss Model on the Portuguese Banking Sector

Miguel Resende, Carla Carvalho, Cecília Carmo

Subject: Business, Economics And Management, Accounting And Taxation Keywords: IFRS 9; expected credit loss; loan loss provision; loan loss allowances; day one; bank

Online: 29 March 2024 (14:27:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0301.v1

Managerial Myopia and Enterprise ESG Performance – Based on the Co-inhibiting Effect of Green Investment and Continuous Innovation

Lingling Cao, Hong Jiang, Huawei Niu

Subject: Business, Economics And Management, Business And Management Keywords: Managerial myopia; ESG performance; Green investment; Green sustainable innovation

Online: 6 August 2024 (02:58:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1704.v1

Vision System for the Mars Sample Return Capture, Containment and Return System (CCRS)

Brent Jon Bos, David Donovan, John Capone, Chen Wang, Terra Hardwick, Dylan Bell, Yuqing Zhu, Robert Podgurski, Bashar Rizk, Ireneusz Orlowski, Rachel Edison, David Harvey, Brianna Dizzon, Lindsay Haseltine, Kristoffer Olsen, Chad Sheng, Robert Bousquet, Luan Vo, Georgi Georgiev, Kristen Washington, Michael Singer, Stefan Ioana, Anloc Le, Elena Georgieva, Michael Hackett, Michael Ravine, Michael Caplinger, Phillip Coulter, Erin Percy, Charles Torisky, Jean Lauenstein, Kaitlyn Ryder, Michael Campola, Dillon Johnstone, William J. Thomes, Richard G. Schnurr, John McCloskey, Eugenia DeMarco, Ellen Lee, Calinda Yew, Bo Yang, Mingyu Han, Bartosz Blonski

Subject: Engineering, Aerospace Engineering Keywords: Mars; cameras; sample return; space optics

Online: 26 April 2024 (09:33:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.2058.v1

Design of a Novel Multiepitope Vaccine against Glioblastoma by In-Silico Approaches

Sako Mirzaie, Kevin Da Yuan, Heyu Ni, Xiao Yu Wu

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Glioblastoma; vaccine; urokinase plasminogen activator surface receptor; Integrin beta-3; HLA class I

Online: 29 August 2024 (09:57:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0141.v3

The Role of Respiration in Estimation of Net Carbon Cycle: Coupling Soil Carbon Dynamics and Canopy Turnover in a Novel Version of 3D-CMCC Forest Ecosystem Model

Sergio Marconi, Tommaso Chiti, Angelo Nole, Riccardo Valentini, Alessio Collalti

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Forest ecosystem; Fluxnet; Soil respiration; Net ecosystem Exchange; Phenology

Online: 15 June 2017 (15:45:04 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202402.1404.v1

Exploring the Potential Use of Natural Products Together with Alkalization in Cancer Therapy

Masahide Isowa, Reo Hamaguchi, Ryoko Narui, Hiromasa Morikawa, Toshihiro Okamoto, And Hiromi Wada

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: tumor microenvironment; alkalization therapy; natural products; cancer, complementary and alternative medicine

Online: 26 February 2024 (09:30:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0793.v1

A Comparison of Battery Equivalent Circuit Model Parameter Extraction Approaches Based on Electrochemical Impedance Spectroscopy

Yuchao Wu, Balakumar Balasingam

Subject: Engineering, Electrical And Electronic Engineering Keywords: Li-ion battery (LIB); battery parameters estimation; battery management system; electrochemical impedance spectroscopy (EIS); electrical equivalent circuit models (ECM); exhaustive search (ES); least squares (LS); Monte-Carlo run; nonlinear least squares (NLS)

Online: 10 September 2024 (10:59:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1005.v1

Polyvinyl Acetate Binders Undermine the Effectiveness of Biochar-Based Seed Coatings

Sean C. Thomas, Yudong Liu, Esther Tang

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: biochar; polyvinyl acetate; salinity stress; seed coating; seed engineering; seed enhancement

Online: 15 May 2024 (08:38:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1546.v1

Effective Evolutionary Principles for System-of-Systems: Insights from Agent-Based Modeling in Vehicular Networks

Jun-Jie Liu, Jun-Xian Liu, Meng-Meng Zhang

Subject: Engineering, Control And Systems Engineering Keywords: system-of-systems; evolutionary principle; agent-based model; internet of vehicles

Online: 27 February 2024 (11:52:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0078.v1

Resonant Rectifier ICs for Piezoelectric Energy Harvesting Using Low-voltage Drop Diode Equivalents

Amad Ud Din, Seneke Chamith Chandrathna, Jong-Wook Lee

Subject: Engineering, Energy And Fuel Technology Keywords: AC-DC converters; energy harvesting; piezoelectric; rectifier

Online: 20 February 2017 (18:23:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0088.v1

Multi-range Conditional Random Field for Classifying Railway Electrification System Objects

Jaewook Jung, Leihan Chen, Gunho Sohn, Chao Luo, Jong-Un Won

Subject: Engineering, Civil Engineering Keywords: classification; railway; power line; mobile laser scanning data; conditional random field; layout compatibility

Online: 26 September 2016 (09:33:05 CEST)

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Railway has been used as one of the most crucial means of transportation in public mobility and economic development. For efficiently operating railways, the electrification system in railway infrastructure, which supplies electric power to trains, is essential facilities for stable train operation. Due to its important role, the electrification system needs to be rigorously and regularly inspected and managed. This paper presents a supervised learning method to classify Mobile Laser Scanning (MLS) data into ten target classes representing overhead wires, movable brackets and poles, which are recognized key objects in the electrification system. In general, the layout of railway electrification system shows a strong regularity of spatial relations among object classes. The proposed classifier is developed based on Conditional Random Field (CRF), which characterizes not only labeling homogeneity at short range, but also the layout compatibility between different object classes at long range in the probabilistic graphical model. This multi-range CRF model consists of a unary term and three pairwise contextual terms. In order to gain computational efficiency, MLS point clouds is converted into a set of line segments where the labeling process is applied. Support Vector Machine (SVM) is used as a local classifier considering only node features for producing the unary potentials of CRF model. As the short-range pairwise contextual term, Potts model is applied to enforce a local smoothness in short-range graph. While, long-range pairwise potentials are designed to enhance spatial regularities of both horizontal and vertical layouts among railway objects. We formulate two long-range pairwise potentials as the log posterior probability obtained by Naïve Bayes classifier. The directional layout compatibilities are characterized in probability look-up tables which represent co-occurrence rate of spatial relations in horizontal and vertical directions. The likelihood function is formulated by multivariate Gaussian distributions. In the proposed multi-range CRF model, the weight parameters to balance four sub-terms are estimated by applying the Stochastic Gradient Descent (SGD). The results show that the proposed multi-range CRF can effectively classify detailed railway elements, representing the average recall of 97.66% and the average precision of 97.07% for all classes.

Preprint ARTICLE | doi:10.20944/preprints202406.0767.v1

The Impact of Short-Term Rental Accommodation in Urban Tourism: A Comparative Analysis of Tourist and Residents’ Perspectives

Helena Albuquerque, Joana A. Quintela, Jorge Marques

Subject: Social Sciences, Tourism, Leisure, Sport And Hospitality Keywords: local accommodation; urban tourism; impacts; resident’ s perspectives; visitor’ s perspectives

Online: 12 June 2024 (12:24:49 CEST)

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Urban tourism has witnessed significant growth in recent years, driven by various factors that foster the transformation of urban areas into tourist hotspots. These factors include a rising interest in culture and heritage, ongoing urban redevelopment and conversion processes, and the introduction of new experiences and activities. Two particularly influential factors contributing to this growth are low-cost travel, which facilitates more accessible access to urban destinations, and the emergence of new types of accommodation, such as short-term rental (also known as local accommodation or Airbnb-type accommodation). This sudden and continuous growth of this type of tourist accommodation brings new challenges to cities and local communities. On the positive side, it contributes to job opportunities, the dynamism of the local economy, and urban revitalization. On the other hand, it also represents more difficulty in retaining the local population in city centers, as more and more buildings are converted into hostels and tourist apartments. In this context, it becomes essential to conduct studies evaluating the impacts of these dynamics in urban areas and how they influence residents' and visitors' perspectives. Therefore, this study aims to identify the main transformations resulting from short-term rental (STR) development, focusing on the impacts felt by tourists and residents in Porto. A questionnaire was distributed to tourists and residents in Porto's city center in June 2023. The results reveal differences in opinions between tourists and residents, particularly concerning historical heritage preservation, local population relocation, and reduced housing availability for residents. Nevertheless, there is a similarity in their opinions regarding the stimulus that local accommodation brings to the economy and the rehabilitation of buildings and urban areas. This study reinforces the need to pay more attention to the future development of tourist accommodation in city centers, especially regarding local policies and territorial planning, to balance better tourism development and local communities' quality of life.

Preprint ARTICLE | doi:10.20944/preprints202404.0961.v1

The Preventive Potential of the Mycelial Submerged Culture of Ophiocordyceps sinensis against Neurodegenerative Diseases and Its Possible Active Compounds

Hsien-Chi Huang, Yu-Juan Shi, Thuy-Lan-Thi Vo, Tai-Hao Hsu, Tuzz-Ying Song

Subject: Medicine And Pharmacology, Complementary And Alternative Medicine Keywords: Ophiocordyceps sinensis; neurodegenerative disease; microglial; anti-inflammatory; cytokines; submerged culture

Online: 15 April 2024 (11:29:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0704.v1

Workers’ Exposure to Chemical Risk in Small and Medium-Sized Enterprises: Assessment Methodology and Field Study

Daniel Onuț Badea, Doru Costin Darabont, Iulian Ivan, Vicențiu Ciocîrlea, Raluca Aurora Stepa, Oana Roxana Chivu

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: chemical hazards; occupational safety and health; risk assessment method workers

Online: 9 July 2024 (07:58:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0039.v1

Numerical Simulation of a Vortex Combustor Based on Aluminum and Steam

Xianhe Chen, Zhixun Xia, Liya Huang, Likun Ma

Subject: Computer Science And Mathematics, Mathematics Keywords: aluminum particle; steam; vortex combustor; diffusion flame; numerical simulation

Online: 12 October 2016 (10:11:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0890.v1

Characterization of Industrial High-Strength Aluminum Alloys by Laser-Induced Breakdown Spectroscopy, With Special Emphasis on the Detection of Low Contents of Mg, Mn, Cr, Cu, Zn and Sensing of Molecular Diatomic Emission of AlO During Ablation

Svetlana Rytchkova, Luc Lévesque

Subject: Physical Sciences, Optics And Photonics Keywords: Laser-induced breakdown spectroscopy (LIBS); Aluminum (Al); Magnesium (Mg); Manganese (Mn); Chromium (Cr); Copper (Cu); Zinc (Zn); Aluminum Monoxide (AlO).

Online: 16 February 2024 (07:01:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1438.v1

The Impacts of Frozen Material-Other-Than-Grapes (MOG) on Aroma Compounds of Cabernet Franc and Cabernet Sauvignon

YIBIN LAN, Xiaoyu Xu, Jiaming Wang, Emily Aubie, Marnie Crombleholme, Andrew Reynolds

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Monoterpenes; norisoprenoids; esters; higher alcohols; sensory analysis; mechanical harvesting

Online: 20 June 2024 (13:03:43 CEST)

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An undesirable sensory attribute (“floral taint”) has been recently detected in red wines in some winegrowing jurisdictions in North America (e.g. Ontario, British Columbia, Washington), caused by introduction of frost-killed leaves and petioles [materials-other-than-grapes (MOG)] during mechanical harvest and winemaking. It was hypothesized that terpenes, norisoprenoids, and higher alcohols would be the main responsible compounds. Objectives were to investigate causative volatile compounds for floral taint, and explore threshold concentrations for this problem. Commercial wines displaying varying intensities of floral taints were subjected to GC-MS and sensory analysis. Several odor-active compounds were higher in floral-tainted wines, including terpenes (geraniol, citronellol, cis- and trans-rose oxide), norisoprenoids (β-damascenone, β-ionone), five ethyl esters, and three alcohols. Thereafter, fermentations of Cabernet franc (CF) and Cabernet Sauvignon (CS) (2016, 2017) were conducted. MOG treatments were (wt/wt): 0, 0.5%, 1%, 2% and 5% petioles, and 0, 0.25%, 0.5%, 1%, and 2% leaf blades. Terpenes (linalool, geraniol, nerol, nerolidol, citronellol, citral, cis- and trans-rose oxides, eugenol, myrcene), norisoprenoids (α- and β-ionone), and others (e.g. hexanol, octanol, methyl and ethyl salicylate) increased linearly/quadratically with increasing MOG levels in both cultivars. Principal components analysis separated MOG treatments from the controls with 5% petioles and 2% leaves as extremes. Increasing MOG levels in CF wines increased floral aroma intensity, and were primarily associated with terpenes, higher alcohols, and salicylates. Increased leaf levels in CF were associated with higher vegetal and earthy attributes. Increased petioles in CS were not correlated with floral aromas, but increased leaves increased floral, vegetal and herbaceous attributes. Overall, petioles contributed more to floral taint than leaves through increased terpenes and salicylates (floral notes), while leaves contributed norisoprenoids and C6 alcohols (green notes).

Preprint ARTICLE | doi:10.20944/preprints202405.0564.v1

A Novel Mastadenovirus from N. noctula which Represents a Distinct Evolutionary Branch of Viruses Infecting Bats in Europe

Anna S. Speranskaya, Alexander V. Dorokhin, Elena V. Korneenko, Ivan K. Chudinov, Andrei E. Samoilov, Sergey V. Kruskop

Subject: Biology And Life Sciences, Virology Keywords: Chiroptera; European bat mastadenoviruses; novel species; viral distribution; Vespertilionidae; Nyctalus noctule; Pipistrellus nathusii

Online: 9 May 2024 (07:16:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1441.v1

Effects of Oxygen Content on Microstructure and Creep Property of Powder Metallurgy Superalloy

Yufeng Liu, Shaorong Zhang, Lichong Zhang, Liang Zheng, Zhou Li, Lin Zhang, Guoqing Zhang

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: powder metallurgy superalloy; oxygen content; prior particle boundary; creep

Online: 25 March 2024 (13:19:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202405.1572.v1

Simulation of the Active Corrector of Power Factor as a Means of Improving the Electromagnetic Compatibility and Energy Efficiency of Electric Locomotive’s Auxiliary Electric Drive

Anatoliy Lavrentyev, Mikhail Pustovetov

Subject: Engineering, Electrical And Electronic Engineering Keywords: power factor active correction; cascaded loops control; AC electric locomotive; auxiliary electric drive; current control loop; voltage control loop; energy saving; electromagnetic compatibility

Online: 23 May 2024 (16:55:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1735.v1

Return to Work After Breast Cancer. A One-Year Mixed-Method Study

Nicola Magnavita, Igor Meraglia, Daniela Andreina Terribile

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: disability management; longitudinal study; welfare; sleep, anxiety; depression; fatigue; work organization; barriers; facilitators; workplace

Online: 26 June 2024 (05:09:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0111.v1

Stakeholders’ Perception on National Heatwave Plans and Their Local Implementation in Belgium and The Netherlands

Joris Adriaan Frank Van Loenhout, José Manuel Rodriguez-Llanes, Debarati Guha-Sapir

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Heatwaves; health protection; perception; key informant interviews

Online: 26 October 2016 (09:52:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0149.v1

Residential Sizing of Solar Photovoltaic Systems and Heat Pumps for Net Zero Sustainable Thermal Building Energy

Shafquat Rana, Uzair Jamil, Nima Asgari, Koami S. Hayibo, Julia Groza, Joshua M. Pearce

Subject: Engineering, Energy And Fuel Technology Keywords: photovoltaic; heat pump; residential; net zero; building energy; solar energy

Online: 3 May 2024 (11:22:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2165.v1

Bemotrizinol-Loaded Nanostructured Lipid Carriers for the Development of Sunscreen Emulsions

Maria Grazia Sarpietro, Debora Santonocito, Francesco Castelli, Stefano Russo, Carmelo Puglia, Lucia Montenegro

Subject: Chemistry And Materials Science, Nanotechnology Keywords: bemotrizinol; nanostructured lipid carriers; sunscreens; emulsions; organic UV-filters

Online: 26 July 2024 (12:54:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0567.v1

Investigating Hydrological Drought Characteristics and Different Return Periods in Semi-Arid Regions under CMIP5 Climate Change Scenarios

Sornsawan Chatklang, Piyapong Tongdeenok, Naruemol Kaewjampa

Subject: Environmental And Earth Sciences, Environmental Science Keywords: climate change; CMIP5; Hydrological Drought Characteristics; Streamflow Drought Index (SDI)

Online: 8 August 2024 (12:05:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1735.v1

Co-management Effects on Forest Restoration in Protected Areas of Bangladesh: A Remote Sensing and GIS-based Analysis

Md Rezaul Karim, Md Abdul Halim, Imrul Kayes, Wenxi Liao, Sharif A. Mukul, Tuihedur Rahman, Sean Thomas

Subject: Biology And Life Sciences, Forestry Keywords: Co-management; protected area; vegetation cover; vegetation indices; tropical forest; Bangladesh

Online: 23 August 2024 (13:31:33 CEST)

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Co-management is increasingly recognized as an effective approach of forest governance while recognizing local people's forest dependency and traditional rights. Moreover, co-management is expected to positively impact forest cover and ecosystem health. Bangladesh, facing a rapid decline in forest cover, has one of the lowest per capita forest areas worldwide. For quite a while, co-management practices have been used to improve forest cover and the livelihoods of forest-dependent people in Bangladesh. Several studies have assessed the efficacy of co-management in different protected areas in Bangladesh from livelihood, social, and cultural aspects. However, the overall changes in forest cover due to co-management from the very beginning of co-management initiatives in the country have been overlooked. We used remotely sensed Landsat images to assess the changes in forest cover and overall land use in five forest protected areas where co-management was piloted. Three major vegetation indices (NDVI, EVI, and MSAVI) were examined to ensure the study's robustness. This study aims to assess the scope and weaknesses of the current policy that incorporates co-management in the country's first five protected areas (SNP, LNP, RKWS, TWS, and CWS), which were brought under co-management in 2003, and compare the efficacy of the co-management relative to non-comanaged protected areas (RRF). The land cover analysis based on NDVI, MSAVI, and EVI values indicated dominant dense forest coverage (41–71%) across five protected areas. During the co-management period (2004–2015), there was a significant decrease in the dense forest proportion, with slopes ranging from -3.7 to -0.96. Similarly, the RRF showed a decreasing pattern, with the slope of the decreasing trendline ranging from -0.48 to -0.62 across the three indices. Agriculture and forest-agriculture mosaics showed a significant increase, with varying slopes among protected areas in both co-managed and non-comanaged sites. Pixel-to-pixel changes revealed dynamic shifts in vegetation indices, and Global Forest Watch data highlighted forest cover losses, notably in CWS (158.77 ha) and SNP (0.49 ha).

Preprint SHORT NOTE | doi:10.20944/preprints202408.0792.v1

Microplastics and Morphometrics Relationship in Coastal Fish

Edison Roi Macusi, Jerald Jumag, Ginalyn Cuenca-Ocay, Michael Bersaldo

Subject: Environmental And Earth Sciences, Environmental Science Keywords: fishgut; fish ingestion; Governor Generoso; marine fish; microplastics

Online: 12 August 2024 (13:26:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0114.v1

Volunteering as Meaningful Activity for People Living with Young Onset Dementia: A Thematic ‘Co-Analysis’

Rose E Vincent, Rosalie Ashworth, Irene Donaldson, Julie Hayden, Gerald King, Chris Maddocks, Keith Oliver, Martin Robertson, Tom C Russ, Heather Wilkinson

Subject: Social Sciences, Sociology Keywords: volunteering; post-diagnosis; young-onset dementia; early-onset dementia; meaningful activity; purpose; co-production

Online: 2 May 2024 (09:47:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0059.v1

Optimization of Lactoperoxidase and Lactoferrin Separation on an Ion-Exchange Chromatography Step

Naeimeh Faraji, Yan Zhang, Ajay K. Ray

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: cation exchange chromatography; minor milk protein; response surface modeling; simulation; steric mass action (SMA); optimization

Online: 12 January 2017 (09:59:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0332.v1

Interpolation of Nitrogen Fertilizer Use in Canada from Fertilizer Use Surveys

James Arthur Dyer, Angela Pearson, Raymond Louis Desjardins

Subject: Environmental And Earth Sciences, Soil Science Keywords: Nitrogen fertilizer rates; Fertiliizer use surveys; Survey histograms; Non-parametric deviation estimates; Crop area integrations; GHG emissions

Online: 3 July 2024 (10:11:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202201.0450.v1

Crowding in or crowding out? Public Investment and Private Investment in South Africa: An ECM Approach

Dumisani Pamba

Subject: Business, Economics And Management, Economics Keywords: Credit to Private Sector; Foreign Direct Investment; Government Consumption Expenditure; Public Investment; Error Correction Model and South Africa

Online: 31 January 2022 (11:15:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0602.v1

The Misalignment between the Strategic Asset Allocation and ESG Investment Target of Institutional Investors

Seonghun Min

Subject: Business, Economics And Management, Finance Keywords: ESG Investment; Sustainable Investment; Strategic Asset Allocation; ESG Investment Target; Misalignment

Online: 8 July 2024 (09:49:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0043.v1

Urban Flood Analysis Model for Plain Tidal River Network Region

Nianqiang Zhang, Na Li, Jing Wang, Sheng Chen, Shaowei Qiu

Subject: Engineering, Control And Systems Engineering Keywords: plain river network; urban flood; flood analysis; Shanghai; Puxi Flood Protected Area

Online: 9 January 2017 (07:17:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.1238.v1

Diversity and Anti-infectious Components of Cultivable Rhizosphere Fungi Derived from Three Species of Astragalus Plants in Northwestern Yunnan, China

Guo-Jun Zhou, Wei-Jia Xiong, Wei Xu, Zheng-Rong Dou, Bo-Chao Liu, Xue-Li Li, Hao Du, Hai-Feng Li, Yong-Zeng Zhang, Bei Jiang, Kai-Ling Wang

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Astragalus; rhizosphere fungi; species diversity; secondary metabolites；antibacterial activity; antimalarial activity; special eco-environment

Online: 16 August 2024 (11:59:09 CEST)

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Astragalus plants belong to the legume family and have obvious rhizosphere effect. The northwestern area of Yunnan China is the main distribution region of Astragalus plants with high application value, but low recognition and resource reserves. The aim of this research is to explore the species diversity of cultivable rhizosphere fungi derived from A. acaulis, A. forrestii, and A. ernestii growing in special high-cold environment of northwest Yunnan, and discover anti-infective components from these fungi. A total of 93 fungal strains belonging to 38 species in 18 genera were isolated and identified. Antibacterial and antimalarial screening yielded 10 target strains. Among them, the ethyl acetate crude extract of the fungus Aspergillus calidoustus AA12 from A. acaulis fermentation substance showed a broad antibacterial spectrum and the best antimalarial activity. Further chemical investigation led to the first discovery of seven compounds from the species of A. calidoustus, including a sesterterpine 6-epi-ophiobolin G (1), two sesquiterpenes penicisochroman A (2), pergillin (3) and 7-methyl-2-(1-methylethylethlidene)-furo[3,2-H]isoquinoline-3-one (4), and three polyketides trypacidin (5), 1,2-seco-trypacidin (6) and questin (7). Compound 1 exhibited moderate to strong antibacterial activity against six Gram-positive pathogens with the minimum inhibitory concentration (MIC) ranging from 25 to 6.25 μg/mL, and prominent inhibitory effect on the biofilm of Streptococcus agalactiae at MIC value of 3.125 μg/mL. This compound also displayed potent antimalarial activity against Plasmodium falciparum strains 3D7 and chloroquine-resistant Dd2 at the half maximal inhibitory concentration (IC50) values of 3.319 and 4.340 µmol/L at 72 h, respectively. This study contributed to our understanding of the cultivable rhizosphere fungi Astragalus-derived in special high-cold environment and further increased the library of fungi available for natural anti-infectious products screening.

Preprint COMMUNICATION | doi:10.20944/preprints202409.1377.v2

Tellurium-Doped Bioactive Glassinduces Ferroptosis in Osteosarcoma Cells Regardless of FSP1

Elzbieta Pańczyszyn, Mari Lallukka, Mara Gagliardi, Valentina Saverio, Romina Monzani, Marta Miola, Enrica Verné, Marco Corazzari

Subject: Biology And Life Sciences, Life Sciences Keywords: Ferroptosis; Tellurium; osteosarcoma; FSP1; bioactive glass

Online: 19 September 2024 (11:51:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0010.v1

Size Distribution, Seasonal Variations and Sources of Carbonaceous Aerosol in a Typical Industrial City Nanjing in Yangtze River Delta, China

Honglei Wang, Junlin An, Bin Zhu, Lijuan Shen, Qing Duan, Yuanzhe Shi

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: size distribution; OC; EC; seasonal variation; Yangtze River Delta

Online: 1 March 2017 (16:59:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0284.v1

Debt-Financed Public Investment in Developing Countries: Does the Efficiency of Public Investment Matter?

Amarachukwu Anthony Anyanwu

Subject: Business, Economics And Management, Economics Keywords: public debt; government spending efficiency; public investment; public sector corruption

Online: 13 September 2020 (12:09:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1820.v1

Net Zero Agrivoltaic Arrays for Agrotunnel Vertical Growing Systems: Energy Analysis and System Sizing

Nima Asgari, Uzair Jamil, Joshua M. Pearce

Subject: Engineering, Energy And Fuel Technology Keywords: aeroponics; agrivoltaics; agrotunnel; hydroponics; photovoltaic; solar energy; vertical farming

Online: 26 June 2024 (14:43:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202004.0459.v1

Influence of Overcrowding in the Emergency Department on Return Visit within 72 Hours

Dong-uk Kim, Yoo Seok Park, Joon Min Park, Nathan J. Brown, Kevin Chu, Ji Hwan Lee, Ji Hoon Kim, Min Joung Kim

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: emergency department; crowding; return visit; admission; patient satisfaction; quality of healthcare

Online: 25 April 2020 (10:45:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1576.v1

Design and Synthesis of Novels Alkylglycerols based Acetylenic Derivatives from 1,10-Decanediol and Stearolic Acid Analogues of Bioactive Ether Lipids

René Momha

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: acetylenic; alkylglycerol; lipid0; solketal; shark liver oil

Online: 23 May 2024 (16:47:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0763.v1

LKB1 and STRAD Promote Epithelial Ovarian Cancer Spheroid Cell Invasion

Charles B Trelford, Adrian Buensuceso, Emily Tomas, Yudith Ramos Valdes, Owen Hovey, Shawn Li, Trevor G Shepherd

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Epithelial Ovarian Cancer (EOC); Liver Kinase B1 (LKB1); STE20-related Kinase Adaptor Protein (STRAD); Spheroid; Organoid; Mesothelial Clearance; Metastasis

Online: 10 September 2024 (09:00:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0026.v1

Molecular Prevalence, Genetic Diversity, and Tissue Tropism of Bartonella Species in Small Mammals from Yunnan Province, China

Pei-Yu Han, Fen-Hui Xu, Jia-Wei Tian, Jun-Ying Zhao, Ze Yang, Wei Kong, Bo Wang, Li-Jun Guo, Yun-Zhi Zhang

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Bartonella; small mammals; genetic diversity; evolution; tissue tropism

Online: 1 April 2024 (17:07:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0098.v1

Active Return-to-Center Control Based on Torque and Angle Sensors for Electric Power Steering Systems

Pan-Pan Du, Hao Su, Gong-You Tang

Subject: Engineering, Automotive Engineering Keywords: electric power steering systems; torque sensor; angle sensor; state switch; active return-to-center control

Online: 14 March 2018 (04:43:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints201812.0152.v1

Electromagnetic Fields of Lightning Return Strokes-Revisited

Vernon Cooray, Gerald Cooray

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Electromagnetic fields, return strokes, dipole fields, accelerating charges, radiation fields, static fields, velocity fields

Online: 12 December 2018 (15:21:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201811.0314.v1

ROI Detection with Machine Learning for Glottis Images Captured from High-speed Video-endoscopy

Jun Kubota, Randol Spaulding, Chi Zhu, Krzysztof Izdebski, Yuling Yan

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: High-speed video-endoscopy, laryngeal image processing, glottis delineation, Machine Learning, CNN

Online: 13 November 2018 (12:57:10 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.1948.v2

CRISPR/CAS Genome Editing Technology: Implications And Challenges

Taha Nazir, Azharul Islam, Hameed A. Mirza, Sahar Radwan, Nida Taha

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: CRISPR-Cas technology; Endonuclease recycling; Genome Editing; Implications

Online: 12 April 2024 (08:41:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1565.v1

The Impact of R&D Investment on the Performance of Portuguese Companies

Ana Santos, Ana Bandeira, Patrícia Ramos

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: Intangible Assets; Investment; R&D; Financial Performance; Generalized Method of Moments

Online: 24 June 2024 (10:58:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1877.v1

The Determinants of China’s Foreign Direct Investment on Economic Growth of Rwanda

Clemence ABADATA, Tian Ze

Subject: Business, Economics And Management, Economics Keywords: Economic growth; Foreign Direct Investment; Import and Export; Influence Analysis; Labor Force

Online: 29 August 2023 (03:04:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1296.v1

Severity Patterns in COVID-19 Hospitalized Patients in Spain. I-MOVE-COVID-19 Study

Miriam Latorre-Millán, María Mar Rodríguez del Águila, Laura Clusa, Clara Mazagatos, Amparo Larrauri, María Amelia Fernández, Antonio Rezusta, Ana María Milagro

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: COVID-19; SARS-CoV-2; severity; mortality; ventilation; ICU; clinical phenotype

Online: 17 September 2024 (10:01:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0159.v2

Dynamic Evaluation and Optimization of Investment Environment in Node Cities on the Maritime Silk Road

Zeyun Yang, Huan Liu, Chenyu Wang, Chunyan He, Xiang Cheng

Subject: Business, Economics And Management, Finance Keywords: Maritime Silk Road; investment environment; dynamic evaluation; projection pursuit cluster

Online: 14 October 2021 (10:47:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0618.v1

Automatic Double Check Monitoring of Continuous Fluid Excretion and Urine Output

Nicolas Goy, Philippe Beuret, Alexandre Despond, Reza Porouchani, Jean-Jacques Goy

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: urine output; intensive care unit; monitoring; renal function

Online: 10 May 2024 (13:23:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1435.v2

Verifiable Privacy Preservation Scheme for Outsourcing Medical Image to Cloud Through ROI Based Crypto-Watermarking

Chuan Zhou, Yi Zhou, Xinghan An, Yan Liu, Min Wang, XiangZhi Liu

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: sharing secret; data outsourcing; reversible watermarking; chaotic map

Online: 21 September 2023 (11:24:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0294.v1

Machine Learning for Financial Investment Indication

Ariel Vieira de Oliveira, Marcia Cristina Schiavi Dazzi, Anita Maria da Rocha Fernandes, Rudimar Luis Scaranto Dazzi, Paulo Ferreira, Valderi Reis Quietinho Leithardt

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Financial Investment; Machine Learning; Artificial Intelligence.

Online: 20 September 2022 (05:45:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0032.v1

Assessment of Rural Flood Risk and Factors Influencing Household Flood Risk Perception in the Haut-Bassins Region of Burkina Faso, West Africa

Madou Sougué, Bruno Merz, Amadé Nacanabo, Gnibga Issoufou Yangouliba, Ibrahima Pouye, Jean Mianikpo Sogbedji, François Zougmoré

Subject: Environmental And Earth Sciences, Geography Keywords: Burkina Faso; flood risk index; flood risk perception index; influence factors; indicator-based method; ordered logistic modelling

Online: 1 May 2024 (07:31:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1172.v1

Chemical Composition, Antioxidant, and Cytotoxic Effects of Senna rugosa Leaf and Root Extracts on Human Leukemia Cell Lines

Cintia Miranda dos Santos, Debora da Silva Baldivia, David Tsuyoshi Hiramatsu de Castro, José Tarciso de Giffoni Carvalho, Alex Santos Oliveira, Paola dos Santos da Rocha, Jaqueline Ferreira Campos, Sikiru Olaitan Balogun, Caio Fernando Ramalho De Oliveira, Denise Brentan da Silva, Carlos Alexandre Carollo, Kely De Picoli Souza, Edson Lucas dos Santos

Subject: Biology And Life Sciences, Life Sciences Keywords: Natural Products; Anticancer Properties; Cancer; medicinal plants; Chemical profile

Online: 17 May 2024 (15:34:58 CEST)

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Senna rugosa is a species found in the Cerrado and used in folk medicine as a vermifuge and in the treatment of poisonous snakebites accidents. In this work, we identified the main secondary metabolites present in ethanolic extracts of the leaves (ELSR) and roots (ERSR) of S. rugosa and evaluated the potential cytoprotective effect against cellular macromolecular damage, as well as the cytotoxic properties of the extracts on the K562 and Jurkat leukemic cell lines. The identification of metabolites was done by liquid chromatography coupled with mass spectrometry. The antioxidant activities were investigated by direct ABTS•+ and DPPH• radical scavenging methods, protection against oxidative damage in proteins and DNA. The cytotoxic properties were investigated against healthy cells, isolated from human peripheral blood (PBMC) and leukemic cell lines. The leaf extract contains catechin, rutin, epigallocatechin derivatives, kaempferol glycosides, luteolin, and dimeric and trimeric procyanidins, while the root extract profile shows obtusichromoneside derivatives, 2-methoxystypandrone, stilbene derivatives, naphthopyranones, and flavanone derivatives. The extracts showed antioxidant activity, with IC50 of 4.86 ± 0.51 µg/mL and 8.33 ± 0.90 µg/mL in the ABTS assay for ELSR and ERSR, respectively. And in the DPPH• assay, the IC50 was 19.98 ± 1.96 µg/mL for ELSR and 13.37 ± 1.05 µg/mL for ERSR. The extracts protected macromolecules against oxidative damage at concentrations of 5 µg/mL. The cytotoxicity test against leukemic strains was observed after 24 and 48 hours of treatment. After 48 h, results against the K562 cell line demonstrate IC50 of 242.54 ± 2.38 µg/mL and 223.00 ± 2.34 µg/mL for ELSR and ERSR , respectively. While against the Jurkat cell line, these extracts showed IC50 of 171.45 ± 2.25 µg/mL and 189.30 ± 2.27 µg/mL, respectively Results on PBMC viability, demonstrate that the extracts showed selectivity for the leukemic cell lines. Together, our results reveal that the leaves and roots of S. rugosa have completely distinct and complex chemical compositions. This study expands the repertoire of identified chemical compounds and underscores their significant pharmacological potential in conditions related to oxidative stress and leukemia.

Preprint ARTICLE | doi:10.20944/preprints202207.0322.v1

The (big) Role of Family Constellations in Return Migration and Transnationalism

Bresena Kopliku, Elvisa Drishti

Subject: Social Sciences, Geography, Planning And Development Keywords: Albania; family; migration; return; transnationalism

Online: 21 July 2022 (10:45:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints201809.0084.v1

Company Income Taxes and Foreign Direct Investment in Nigeria

Onome Edo, Omoye Alade

Subject: Business, Economics And Management, Economics Keywords: corporate tax; fdi; tax incentives; tax rate; investment

Online: 5 September 2018 (05:10:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0159.v2

Investment and Economic Growth: An Empirical Analysis for Tanzania

Manamba Epaphra, John Massawe

Subject: Business, Economics And Management, Economics Keywords: public investment; domestic private investment; FDI; crowding out effect; economic growth

Online: 30 August 2016 (04:03:38 CEST)

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This paper analyzes the causal effect between domestic private investment, public investment, foreign direct investment and economic growth in Tanzania during the 1970-2014 period. The modified neo-classical growth model is used to estimate the ieffect of investment on economic growth. Also, the economic growth models based on Phetsavong and Ichihashi (2012) [1], and Le and Suruga (2005) [2]are used to estimate the crowding out effect of public investment on domestic private investment on one hand and foreign direct investment on the other hand. In the same way, the crowding out effect of foreign direct investment on domestic private investment is estimated. A correlation test is applied to check the correlation among independent variables, and the results show that there is very low correlation suggesting that multicollinearity is not a serious problem. Moreover, the diagnostic tests including RESET regression errors specification test, Breusch-Godfrey serial correlation LM test, Jacque-Bera-normality test and white heteroskedasticity test reveal that the model has no signs of misspecification and that, the residuals are serially uncorrelated, normally distributed and homoskedastic. Broadly, the empirical results show that the domestic private investment and foreign direct investment play an important role in economic growth in Tanzania. Besides, a revealed negative, albeit weak, association between public and private investment suggests that the positive effect of domestic private investment on economic growth becomes smaller when public investment-to-GDP ratio exceeds 8-10 percent. Similarly, foreign direct investment tends to marginally reduce the impact of domestic private investment on growth. These results suggest that public investment and foreign direct investment need to be considered carefully in order to avoid a reduced positive impact of domestic private investment on growth. Domestic saving may be promoted to encourage domestic investment for economic growth.

Preprint REVIEW | doi:10.20944/preprints202403.0113.v1

Exploring the Nexus between Dental Stem Cells and Maternal Oral Health during Pregnancy: What We Know and What We Don't

Aida Meto, Ana Sula, Samuele Peppoloni, Agron Meto, Elisabetta Blasi

Subject: Public Health And Healthcare, Other Keywords: Dental stem cells; maternal oral health; pregnancy; oral microbiota; regenerative potential; hormonal changes; preventive strategies

Online: 4 March 2024 (05:59:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1556.v1

The Impact of Value Creation (Tobin’s Q), Total Shareholder Return (TSR), and Survival (Altman’s Z) on Credit Ratings

Nazario Augusto Oliveira, Leonardo Fernando Cruz Basso

Subject: Business, Economics And Management, Finance Keywords: credit rating; credit risk; determinants; risk management

Online: 26 March 2024 (13:10:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1189.v1

Research on The Heat Transfer Model of Double U-pipe Ground Heat Exchanger Based on In-Situ Testing

Ruifeng Wang, Mingchuan Shi, Jun Yu, Wei Ren, Guohong Yan, Ke Zhu, Zhiqiang Yin, Shujie Gao

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: In-situ testing; Double U-pipe ground heat exchanger; Heat transfer model; Shallow geothermal energy

Online: 18 April 2024 (11:06:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2319.v1

New Piezoceramic SrBi2Nb2-2xWxSnxO9: Crystal Structure, Microstructure and Dielectric Properties

Sergei V. Zubkov, Ivan A. Parinov, Alexander V. Nazarenko

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: Aurivillius – Smolensky phase; SrBi2Nb2-2xWxSnxO9 (x = 0.1, 0.2, 0.3, 0.4); activation energy Ea; Curie temperature TC, relative permittivity ε/ε0

Online: 29 July 2024 (13:50:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202201.0257.v1

Does Foreign Direct Investment Crowd in or Crowd out Domestic Investment in South Africa? An ARDL-ECM Approach

Dumisani Pamba

Subject: Business, Economics And Management, Economics Keywords: FDI; Domestic Investment; Government Investment Expenditure; Economic Growth; Real exchange rate; Gross Domestic Savings; Trade openness; ARDL-ECM Approach and South Africa

Online: 18 January 2022 (12:42:00 CET)

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The aim of this study is to empirically examine the link between foreign direct investment (FDI) and domestic investment (DI) in South Africa over the period of 41 years (1975-2016). Accurately, it attempts to determine whether FDI crowds in or crowds out DI in South Africa. DI is sub-divided into private domestic investment (credit to domestic private sector) and public corporation investment (state owned enterprises). We used the Autoregressive Distributed Lag-Error Correction Model (ARDL-ECM) technique to ascertain long run and short run effects concurrently after establishing that the variables were stationary (using the PP test). The results of the unit root test shows that all variables are integrated of order zero I(0) or integrated of order one I(1), indicating that the series of variables are stationary in the level or first difference form. The findings revealed that variables are cointegrated in the long run. The ARDL model found a negative link between FDI and domestic investment. The result implies that FDI crowds out domestic investment. Moreover, the long run estimate revealed that domestic investment is crowded in by government investment expenditure (GINV). Other findings uncovered that, GDP crowds out private domestic investment while crowding in public corporation investment. Moreover, the long run estimate revealed that domestic investment is crowded in by gross domestic savings (SAV). On the other hand, the real exchange rate (EXCR) crowds out private domestic investment while crowding in public corporation investment. Trade openness (TRA) crowds out domestic investment. Additionally, the short run estimate uncovered that private domestic investment is crowded out by FDI, EXCR, and TRA whereas GINV, GDP and SAV is crowding in private domestic investment. Other findings discovered that, in the short run, public corporation investment is crowded out by FDI, GDP, EXCR and TRA, while GINV and SAV crowd in public corporation investment. The CUSUM confirms that the models are structurally firmness.

Preprint ARTICLE | doi:10.20944/preprints202407.0763.v1

Efficacy of a Comprehensive and Personalized Approach for Frail Older People in Valencia (Spain): A Pre-Post Controlled Trial

Mirian Fernández-Salido, Tamara Alhambra-Borrás, Jorge Garcés-Ferrer

Subject: Public Health And Healthcare, Primary Health Care Keywords: older people; frailty; value-based healthcare; personalized care; integrated care; pre-post controlled trial

Online: 10 July 2024 (04:17:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0532.v1

DEHA-Net: Dual-Encoder based Hard Attention Network with Adaptive ROI Mechanism for Lung Nodule Segmentation

Muhammad Usman, Yeong Gil Shin

Subject: Computer Science And Mathematics, Computer Science Keywords: lung nodule segmentation; 3D segmentation; dual-encoder-based CNN; hard attention

Online: 28 December 2022 (09:03:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0085.v1

Open-source Hardware Design of Modular Solar DC Nanogrid

Md Motakabbir Rahman, Sara Khan, Joshua M. Pearce

Subject: Engineering, Electrical And Electronic Engineering Keywords: photovoltaic; open source; open hardware; microgrid; nanogrid; DC nanogrid; modular PV system hardware; solar energy; renewable energy

Online: 2 August 2024 (00:06:34 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202402.1633.v1

Small Farm Holder Cropping Systems Influence Microbial Profiles in an Equatorial Rainforest Agroecosystem

Christine Matindu, Nimalka M. Weerasuriya, Francis Muyekho, Irena F. Creed, R. Greg Thorn, Anthony W. Sifuna

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: cropping systems; maize-bean; microbial profiles; sugarcane; soil properties; equatorial rainforest

Online: 28 February 2024 (13:48:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1604.v1

A Acylhydrazone Compound A5 Promotes Neurogenesis by Up-regulating Neurogenesis-related Genes and Inhibiting Cell-cycle Progression in Neural Stem/Progenitor Cells

Xiaoliang Xiang, Xia Jiang, Hongwei Lin, Meixing Yu, Liming Wu, Rong Zhou

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: acylhydrazone compound; neural stem/progenitor cells; neurogenesis; cell-cycle progression; neurodegenerative diseases

Online: 24 April 2024 (10:07:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0557.v1

Clinical Significance of Whole-Body Computed Tomography Scans in Pediatric Out-of-Hospital Cardiac Arrest Patients Without Prehospital Return of Spontaneous Circulation

Masanori Ishida, Taro Tanaka, Shinichiro Morichi, Hirotaka Uesugi, Haruka Nakazawa, Shun Watanabe, Motoki Nakai, Gaku Yamanaka, Hiroshi Homma, and Kazuhiro Saito

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: computed tomography; pediatric patient; out-of-hospital cardiac arrest; return of spontaneous circulation

Online: 6 September 2024 (16:53:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.1158.v1

Respiratory Syncytial Virus Vaccines: Analysis of the Pre-Marketing Clinical Trial for Immunogenicity in the Population over 50 Years of Age

Georgios Papazisis, Xanthippi Topalidou, Georgia Gioula, Pablo A. González, Susan M Bueno, Alexis M Kalergis

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: immunosenescence; inflammaging; vaccinology; respiratory syncytial virus; aging; elderly; clinical trials

Online: 20 February 2024 (14:30:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0370.v1

The Effect of R&D Investment of Chinese Companies on Business Innovation Performance

EnLu Jiang, ZhengGuang Li

Subject: Business, Economics And Management, Accounting And Taxation Keywords: R&D Investment; Industry Diversification; Technology Diversification; Business Innovation.

Online: 6 February 2024 (13:07:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1386.v1

Executives Implicated in Financial Reporting Fraud and Firms’ Investment Decisions

Moon Kyung Cho, Minjung Kang

Subject: Social Sciences, Government Keywords: Fraud; Implicated Executives; Colluded Executives; Firms’ Investment Decisions; Sustainability

Online: 22 April 2024 (10:29:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.2001.v1

Open-Source Indoor Horizontal Grow Structure Designs

Jun-yu Qian, Joshua M. Pearce

Subject: Engineering, Mechanical Engineering Keywords: indoor growing; grow bins; aeroponic; hydroponic; mechanical design; distributed fabrication; open hardware; controlled environmental agriculture; sustainable agriculture; agriculture

Online: 28 August 2024 (10:44:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1163.v1

Assessment of the Efficacy of the Antihistamine Drug Rupatadine Used Alone or in Combination against Mycobacteria

Xirong Tian, Wanli Ma, Buhari Yusuf, Biyi Su, Jinxing Hu, Tianyu Zhang

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Mycobacteria; Drug resistance; Rupatadine; Drug repurposing; Nonreplicating

Online: 17 June 2024 (15:53:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1730.v1

Biochar and Deactivated Yeast as Seed Coatings for Restoration: Performance on Alternative Substrates

Jennifer Cann, Esther Tang, Sean C. Thomas

Subject: Environmental And Earth Sciences, Environmental Science Keywords: biochar; charcoal, clover; ecological restoration; inactive brewer’ s yeast; mine tailings; revegetation; seed coatings; seed germination; seedling establishment

Online: 22 July 2024 (17:38:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0084.v1

A Novel Virtual Torque Sensor for Rescue Robots with Harmonic Drives

Kerui Xia, Liang Ding, Guangjun Liu, Haibo Gao, Zongquan Deng

Subject: Engineering, Control And Systems Engineering Keywords: robot joint; virtual torque sensor; Gaussian process regression; harmonic drive compliance model

Online: 23 September 2016 (09:52:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0306.v1

Intraday Return Reversals: Empirical Evidence from the Korean ETF Market

Sangki Lee, Chung-hun Hong

Subject: Business, Economics And Management, Finance Keywords: return reversals; exchange-traded funds (ETFs); attention hypothesis; disagreement hypothesis; short selling

Online: 27 May 2019 (09:53:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0267.v1

Diﬀerential Eﬀects of Nitrogen and Phosphorus Fertilization Rates and Fertilizer Placement Methods on P Accumulations in Maize

Sharifullah Sharifi, Songmei Shi, Hikmatullah Obaid, Xingshui Dong, Xinhua He

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: broadcast; deep band; phosphorus accumulation; phosphorus use efficiency; side band; Zea mays

Online: 6 May 2024 (08:38:39 CEST)

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Crop production in Afghanistan suffers from limited phosphorus (P) availability, which severely hinders national agriculture sustainability. This present study hypothesized that deep fertilizer placement could significantly enhance uptake of immobile P and thus tissue P accumulation and crop yield. A two-year pot experiment growing two maize (Zea mays) hybrid cultivars (Xida-789 and Xida-211) was therefore conducted to test these hypotheses under three contrasting fertilizer placement methods (broadcast, side band, and deep band). In doing so, P concentrations in both maize tissues and soils were compared at 45, 60, and 115 days after sowing (DAS) under nine combinations of nitrogen (N) and P fertilizer rates (kg ha-1: N112P45, N112P60, N112P75, N150P45, N150P60, N150P75, N187P45, N187P60, N187P75). Results have shown that deep band placement significantly increased P uptake efficiency, leading to greater P concentration and accumulation in maize tissues compared to other two fertilization methods. This improved P uptake was attributed to several factors associated with deep placement, including reduced P fixation, enhanced root access to P, and moisture availability for P uptake. Additionally, deep band placement combined with higher N application rates (N187 and N150) further enhanced plant P uptake by promoting P availability and utilization mechanisms. Deep band placement also resulted in significantly higher total soil P, Olsen-P, and P use efficiency than broadcast and side band methods, indicating a more efficient P fertilization strategy for maize that can improve growth and yield. This present study also found positive correlations between P concentration in plant organs and soil Olsen-P, highlighting the importance of adequate soil P levels for optimal plant growth. Overall, our results have showed that deep band fertilizer placement emerged as a superior strategy for enhancing P uptake efficiency, utilization, and maize productivity compared to broadcast and side band placement. This approach can potentially optimize P fertilizer utilization, improve maize growth and yield, while minimizing environmental P losses associated with broadcast applications.

Preprint ARTICLE | doi:10.20944/preprints202204.0094.v1

Be Nice to Thy Neighbours: Spatial Impact of Foreign Direct Investment on Poverty in Africa

Sodiq Arogundade, Mduduzi Biyase, Santos Bila

Subject: Business, Economics And Management, Economics Keywords: FDI; Driscoll-Kraay fixed effect instrumental variable regression; IV-GMM; Spatial Durbin Model; Poverty; Institutional quality; Africa

Online: 11 April 2022 (10:58:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0635.v1

Endometrial Proliferative Phase-Centered View on the Transcriptome Dynamics Across the Menstrual Cycle

Apostol Apostolov, Mladen Naydenov, Aive Kalinina, Maria Nikolova, Merli Saare, Elina Aleksejeva, Nadezhda Milova, Antoan Milov, Andres Salumets, Vesselin Baev, Galina Yahubyan

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: endometrial cycle; mid-proliferative phase; late-proliferative phase; early-secretory phase; mid-secretory phase; late-secretory; transcriptome profiles

Online: 9 April 2024 (11:42:51 CEST)

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The endometrium, the inner mucosal lining of the uterus, undergoes complex molecular and cellular changes across the menstrual cycle in preparation for embryo implantation. Transcrip-tome-wide analyses have mainly been utilized to study the endometrial receptivity, the prerequisite for successful implantation, with most of the studies, so far, comparing the endometrial transcriptomes between (i) secretory versus proliferative endometrium or (ii) mid-secretory versus early-secretory endometrium. In the current study, we provide the complete transcriptome description of the endometrium across the entire menstrual cycle and, for the first time, comprehensively characterize the proliferative phase of the endometrium. Our temporal transcriptome analysis includes five time points: mid-proliferative, late-proliferative (peri-ovulatory phase), early-secretory, mid-secretory, and late-secretory phases. Thus, we exhaustively unveil the transitions between the consecutive proliferative and secretory phases, highlighting their unique gene expression profiles and possible distinct biological functions. Transcriptome analysis reveals many differentially expressed genes (DEGs) across the menstrual cycle, most of which are phase-specific. As an example of the coordinated gene activity, the expression profile of his-tone-encoding genes within the HIST cluster on chromosome 6 showed an increase in cluster activity during the late-proliferative and a decline during the mid-secretory phase. Moreover, numerous DEGs are shared among all phases. In conclusion, in the current study, we delineate the endometrial proliferative phase-centered view of transcriptome dynamics across the menstrual cycle. Data analysis highlights significant transcriptomic and functional changes occurring during the late-proliferative phase – an essential transition point from the proliferative to the secretory phase. Future studies should explore how the biology of the late-proliferative phase endometrium impacts the achievement of mid-secretory endometrial receptivity or contributes to molecular aberrations leading to embryo implantation failure.

Preprint ARTICLE | doi:10.20944/preprints202304.0739.v1

Outperforming the S&P 500 through Investment Plays

Nicolas Pfister, Michael J. Kendzia

Subject: Business, Economics And Management, Finance Keywords: Value stocks; spin-offs; turnarounds; P/E ratio; P/B ratio

Online: 23 April 2023 (03:21:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202203.0217.v1

Strategic Investment in Open Hardware for National Security

Joshua M. Pearce

Subject: Engineering, Energy And Fuel Technology Keywords: energy policy; energy conservation; climate change; global safety; open hardware; open source; photovoltaic; renewable energy; solar energy; national security

Online: 15 March 2022 (14:27:35 CET)

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Working Paper ARTICLE

Estimation of the Efficiency of the Investment Fund

Eduard Dadyan

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: Efficiency of mutual funds, a deep crisis in the economy, efficiency forecast, model formation, financial investments, estimated income, mutual funds, CAPM, neural networks

Online: 31 March 2021 (22:04:28 CEST)

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