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Preprint ARTICLE | doi:10.20944/preprints202012.0447.v1

Optimizing Return to Play After Anterior Cruciate Ligament Reconstruction in Soccer Players: an Evidence Based Approach

Florian Forelli, Clément Sansonnet, Steeve Chiapolini, Jean Mazeas, Amaury Vandebrouck, Pascal Duffiet, Louis Ratte, Maude Traullé

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Injury mechanism; Muscle strengthening; Neuromotor; Neurocognitive; Injury Prevention

Online: 18 December 2020 (08:34:06 CET)

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Preprint ESSAY | doi:10.20944/preprints202404.0034.v1

How to Become a Terran. Return to Earth as Geo-Gastro-Politics

Harald Lemke

Subject: Arts And Humanities, Philosophy Keywords: gastroethics; gastrosophy; Slow Food movement; humification; the terrestrial party; everyday activism

Online: 1 April 2024 (11:12:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1735.v1

Return to Work After Breast Cancer. A One-Year Mixed-Method Study

Nicola Magnavita, Igor Meraglia, Daniela Andreina Terribile

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: disability management; longitudinal study; welfare; sleep, anxiety; depression; fatigue; work organization; barriers; facilitators; workplace

Online: 26 June 2024 (05:09:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1486.v1

Matchmaking in Off-Grid Energy System Planning: A Novel Approach for Integrating Residential Electricity Demands and Productive Use of Electricity

Nikolas Schöne, Tim Ronan Britton, Edouard Delatte, Nicolas Saincy, Boris Heinz

Subject: Engineering, Energy And Fuel Technology Keywords: Rural electrification; Productive use of electricity; Off-grid; Community energy; Energy system planning; Sustainable development; Key informant interviews; Energy system modeling; Statis-tical analysis; Co-creation.

Online: 25 March 2024 (13:33:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0463.v1

“So, We Can’t Play”. Limitations To Play at School in Periods of Educational Transition

Pablo Rupin, Carla Muñoz, Daniela Jadue

Subject: Social Sciences, Education Keywords: Early childhood education; play and learning; educational transitions; educational setting; research with children; visual methodologies; qualitative research

Online: 27 February 2023 (09:03:38 CET)

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Preprint REVIEW | doi:10.20944/preprints202407.0916.v1

The Controversial Role of Ubiquitin-Conjugatin Enzyme E2 O (UBE2O) in Human Leukemias and Solid Tumors

Beatrice Maffeo, Daniela Cilloni

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: UBE2O; UPS; ubiquitin; protein degradation; erythropoiesis; leukemia; solid tumors

Online: 11 July 2024 (04:52:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints202104.0148.v1

Play Therapy to Reduce Anxiety in Children

Wahyu Endang Setyowati, Moses Glorino Rumambo Pandin

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: play therapy; anxiety; children

Online: 5 April 2021 (14:33:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.2328.v3

An Assessment of Agent-Based Modelling Tools for Community-Based Adaptation to Climate Change

Tom Selje, Rayhan Islam, Boris Heinz

Subject: Social Sciences, Other Keywords: Community-based adaptation; climate change adaptation; agent-based modelling; simulations; tool assessment

Online: 16 September 2024 (09:35:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.0059.v1

Calcineurin Inhibitors in Atopic Dermatitis

Ajit B Janagond, Arun C Inamadar

Subject: Medicine And Pharmacology, Dermatology Keywords: atopic dermatitis; calcineurin; NFAT; tacrolimus; pimecrolimus; cyclosporine

Online: 1 May 2024 (07:49:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1704.v1

Vision System for the Mars Sample Return Capture, Containment and Return System (CCRS)

Brent Jon Bos, David Donovan, John Capone, Chen Wang, Terra Hardwick, Dylan Bell, Yuqing Zhu, Robert Podgurski, Bashar Rizk, Ireneusz Orlowski, Rachel Edison, David Harvey, Brianna Dizzon, Lindsay Haseltine, Kristoffer Olsen, Chad Sheng, Robert Bousquet, Luan Vo, Georgi Georgiev, Kristen Washington, Michael Singer, Stefan Ioana, Anloc Le, Elena Georgieva, Michael Hackett, Michael Ravine, Michael Caplinger, Phillip Coulter, Erin Percy, Charles Torisky, Jean Lauenstein, Kaitlyn Ryder, Michael Campola, Dillon Johnstone, William J. Thomes, Richard G. Schnurr, John McCloskey, Eugenia DeMarco, Ellen Lee, Calinda Yew, Bo Yang, Mingyu Han, Bartosz Blonski

Subject: Engineering, Aerospace Engineering Keywords: Mars; cameras; sample return; space optics

Online: 26 April 2024 (09:33:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1216.v1

Evaluating the Performance of Ensembled YOLOv8 Variants in Smart Parking Applications for Vehicle Detection and License Plate Recognition under Varying Lighting Conditions

Ripunjay Singh, Sarthak Goyal, Shivam Agarwal, Subho Upadhyay

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: YOLOv8; Smart Parking; TOPSIS; Object Detection; YOLOv8 ensembling

Online: 18 April 2024 (10:48:07 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202405.0374.v1

Identifying Disparities and Promoting Environmental Justice for Vulnerable Populations in India

Vina Vaswani, Ifeanyichukwu Akuma

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Ecological backdrop; environmental justice; pollution's toll; human-nature nexus and generational burden

Online: 7 May 2024 (11:42:13 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.2107.v2

Harnessing Biopolymer Gels for Theranostic Applications: Imaging Agent Integration and Real-Time Monitoring of Drug Delivery

Pranita S Jirvankar, Surendra S Agrawal, Nikhita Chambhare, Rishabh Agrawal

Subject: Medicine And Pharmacology, Pharmacy Keywords: Biopolymer gel; Real-Time monitoring; Imaging agent

Online: 9 July 2024 (12:29:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1470.v2

Enhancing Understanding Through Data Visualization: What Can Available Data Reveal About Access to Energy in Displacement Contexts on the African Continent?

Tim Ronan Britton, Philipp Baslik, Lena Anna Schmid, Boris Heinz

Subject: Social Sciences, Geography, Planning And Development Keywords: humanitarian settings; humanitarian energy; electricity; clean cooking; data assessmen

Online: 10 May 2024 (11:30:51 CEST)

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The extent of access to energy of displaced populations in settlements and camps in Africa is largely 14 unknown. A multitude of contextual factors, such as the location and the characteristics of housing, 15 the legal status, the socio-cultural background, and the availability of humanitarian and public ser- 16 vices impact the living conditions and the needed energy services. Limitations in accessing energy 17 services have direct, multilayered, and far-reaching implications, including impacts on health, nu- 18 trition, education, protection, and livelihood. The objective of this article is to contribute to a more 19 comprehensive overview of the current state of energy access in displacement contexts on the Afri- 20 can continent by identifying and utilizing existing data. After a screening of the vast and various 21 available information, setting up of a database, consolidating the gathered data as well as assessing 22 the quality through a quality assessment method, the currently available information is visualized 23 and discussed. Considerable differences in the access to electricity for displaced persons across the 24 countries are found. For both electricity and clean cooking, the availability for displaced persons 25 ranges from nearly no access at all up to an access rate of 100%. More strikingly, the results also 26 show that besides South Africa and countries in the Maghreb region, the access to both clean cook- 27 ing and electricity for displaced persons is very low. At the same time, the fragmented data availa- 28 bility, the poor data quality, and the questionable expediency of available data allows neither solid 29 theoretical conclusions nor planning of effective practical implementation measures. Novel inter- 30 disciplinary research, conceptual frameworks and indicators are needed for the purpose of compa- 31 rability and consistency. Future research has the potential to more comprehensively capture the 32 current state of access to energy in displacements contexts and in a next step to examine how energy 33 is interwoven in the lives of displaced people to derive a set of more detailed context-sensitive en- 34 ergy indicators. It is essential that the concerned persons, the displaced persons themselves are in- 35 cluded in the research in a meaningful way.

Preprint ESSAY | doi:10.20944/preprints202307.1330.v1

Research on E-commerce Platform’s Return Strategies Considering Consumer Abusing Return Policies

Huixin Liu, Feng Du

Subject: Business, Economics And Management, Business And Management Keywords: abuse of return policy; network effect; return policy; platform operation strategy

Online: 19 July 2023 (10:11:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1348.v1

Nuancing 'Emotional' Social Play: Does Play Behaviour Always Underlie a Positive Emotion?

Giada Cordoni, Ivan Norscia

Subject: Biology And Life Sciences, Behavioral Sciences Keywords: cooperation; competition; positive/negative emotions; aggressive play; play signals; rapid motor mimicry

Online: 17 July 2024 (02:58:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0227.v1

Allowing Differently Strong Chess Players to Play at An Equal Level

Arend Hintze

Subject: Computer Science And Mathematics, Computer Science Keywords: chess; elo; evaluation; equal play; handicap

Online: 26 April 2022 (04:41:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0358.v1

Detailed Experiment-Theory Comparison of Mid-Infrared Metasurface Perfect Absorbers

Naoki To, Saulius Juodkazis, Yoshiaki Nishijima

Subject: Physical Sciences, Optics And Photonics Keywords: metasurface; mid infrared absorption; perfect absorption

Online: 27 March 2020 (12:32:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.1321.v1

From Play to Understanding: LLMs in Logic and Spatial Reasoning Coloring Activities for Children

Sebastián Tapia, Roberto Araya

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: LLM; GPT; prompting; quantifiers; visual thinking; coloring activities; support for teachers; correction; feedback

Online: 19 August 2024 (10:42:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.0291.v1

Return to Sports Activity in Individuals with Surgical Stomas: A Scoping Review

Andrea-Victoria Mena-Jiménez, Claudio-Alberto Rodríguez-Suárez, Héctor González-de la Torre

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: Exercise; Return to Sport; Surgical Stomas; Review

Online: 5 August 2024 (14:26:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1540.v1

Community-Based Adaptation to Climate Change: Core Issues and Implications for Practical Implementations

Tom Selje, Lena Anna Schmid, Boris Heinz

Subject: Social Sciences, Geography, Planning And Development Keywords: community-based adaptation; adaptation to climate change; semi-systematic literature review; approach; concept

Online: 21 August 2024 (11:42:32 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.2018.v1

The Precision Medicine: Advancement and Transformation in Cancer Treatment

Samiksha Khobragade, Ujwal Vyas, Anil Pethe, Rahul G Ingle

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Cancer; CRISPR-Cas9; immunotherapy; precision medicine; next generation sequences

Online: 29 June 2024 (04:53:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0821.v1

CSN1S1, CSN3 and LPL, Three Validated Gene’s Polymorphisms Useful for a More Sustainable Dairy Production in the Mediterranean River Buffalo

Alfredo Pauciullo, Giustino Gaspa, Yi Zhang, Qingyou Liu, Gianfranco Cosenza

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Mediterranean river buffalo; CSN1S1; CSN3; LPL; SCD; milk traits; validation study

Online: 11 April 2024 (14:53:59 CEST)

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The search of DNA polymorphisms useful for the genetic improvement of dairy farm animals lasts more than 40 years with relevant findings in cattle for milk traits, where the best combination of alleles for dairy processing have been found in casein genes and in the DGAT1. Nowadays, similar results are not reached yet in river buffaloes despite advanced genomic technologies and accurate phenotype records are available. The aim of the present study was to investigate and validate in a larger buffalo population the effect on six milk traits of four single nucleotide polymorphisms (SNP) in the CSN1S1, CSN3, SCD and LPL genes, previously reported to be associated with or affect dairy traits in smaller populations often belonging to one farm. A total of 800 buffaloes were genotyped. Daily milk yield (dMY, kg), protein yield (dPY, kg) and fat yields (dFY, kg), fat and protein contents (dFP, % and dPP, %), somatic cell count (SCC, 103cell/ml) and urea (mg/dl) were individually recorded in each month for the whole lactation from 2010 to 2021. A total of 15,742 individual milk test day records (2,496 lactations) were available on 680 buffalo cows with 3.6±1.7 parity (from 1 to 13) and 6.1±1.2 test day records per lactation on average. Three out four SNP in CSN1S1, CSN3 and LPL were associated with at least one of analyzed traits. In particular, the CSN1S1 (AJ005430:c.578C>T) gave favorable associations with all yield traits (dMY, p=0.022; dPY, p=0.014 ; dFY, p=0.029) and SCS (p=0.032), whereas the CSN3 (HQ677596: c.536C>T) positively associated with SCS (p=0.005) and milk urea (p=0.04). Favorable effect on dMY (p=0.028), dFP (p=0.027) and dPP (p=0.050) were observed for the LPL. Conversely, SCD did not show any association with milk traits. This is the first example of confirmation study carried out in the Mediterranean river buffalo for genes of economic interest in dairy field and it represents a very important indication for the preselection of young bulls destined to breeding programs in the view of a more sustainable dairy production.

Preprint ARTICLE | doi:10.20944/preprints202409.1296.v1

Severity Patterns in COVID-19 Hospitalized Patients in Spain. I-MOVE-COVID-19 Study

Miriam Latorre-Millán, María Mar Rodríguez del Águila, Laura Clusa, Clara Mazagatos, Amparo Larrauri, María Amelia Fernández, Antonio Rezusta, Ana María Milagro

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: COVID-19; SARS-CoV-2; severity; mortality; ventilation; ICU; clinical phenotype

Online: 17 September 2024 (10:01:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1487.v2

Plug-and-Play: An Efficient Post-training Pruning Method for Large Language Models

Yingtao Zhang, Haoli Bai, Haokun Lin, Jialin Zhao, Lu Hou, Carlo Vittorio Cannistraci

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: post-training pruning; combinatorial optimization; large language models; inference acceleration

Online: 27 May 2024 (08:34:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0573.v1

Determination and Quantification of Acetaldehyde, Acetone and Methanol in Hand Sanitizes Using Headspace GC-MS: Effect of Storage Time and Temperature

Jacob Abraham Theruvathu, Chessa To

Subject: Chemistry And Materials Science, Other Keywords: Hand sanitizer; alcohol; acetaldehyde; acetone; GC/MS; isotope; storage time; temperature

Online: 9 November 2023 (07:25:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0272.v1

Formate Dehydrogenase (FDH1) Localizes to Both Mitochondria and Chloroplast to Play a Role in Host and Nonhost Disease Resistance

Seonghee Lee, Ramu S. Vemanna, Sunhee Oh, Clemencia M. Rojas, Youngjae Oh, Amita Kaundal, Taegun Kwon, Hee-Kyung Lee, Senthil-Kumar Muthappa, Kirankumar S. Mysore

Subject: Biology And Life Sciences, Plant Sciences Keywords: biotic stress; plant defense response; hypersensitive response; programmed cell death; reactive oxygen species

Online: 12 July 2020 (18:50:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0344.v1

Immune-Inflammatory Response in Lifespan. What Role Does It Play in Extreme Longevity? A Sicilian Semi- and Supercentenarians Study

Giulia Accardi, Anna Calabrò, Rosalia Caldarella, Calogero Caruso, Marcello Ciaccio, Marta De De Simone, Mattia Emanuela Ligotti, Serena Meraviglia, Rosa Zarcone, Giuseppina Candore*, Anna Aiello

Subject: Biology And Life Sciences, Aging Keywords: Aging; ARIP; Biological Aging; Immune-inflammatory response; Inflamm-aging; INFLA-score; Longevity; Semi-supercentenarians; SIRI

Online: 6 June 2024 (04:54:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1172.v1

Chemical Composition, Antioxidant, and Cytotoxic Effects of Senna rugosa Leaf and Root Extracts on Human Leukemia Cell Lines

Cintia Miranda dos Santos, Debora da Silva Baldivia, David Tsuyoshi Hiramatsu de Castro, José Tarciso de Giffoni Carvalho, Alex Santos Oliveira, Paola dos Santos da Rocha, Jaqueline Ferreira Campos, Sikiru Olaitan Balogun, Caio Fernando Ramalho De Oliveira, Denise Brentan da Silva, Carlos Alexandre Carollo, Kely De Picoli Souza, Edson Lucas dos Santos

Subject: Biology And Life Sciences, Life Sciences Keywords: Natural Products; Anticancer Properties; Cancer; medicinal plants; Chemical profile

Online: 17 May 2024 (15:34:58 CEST)

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Senna rugosa is a species found in the Cerrado and used in folk medicine as a vermifuge and in the treatment of poisonous snakebites accidents. In this work, we identified the main secondary metabolites present in ethanolic extracts of the leaves (ELSR) and roots (ERSR) of S. rugosa and evaluated the potential cytoprotective effect against cellular macromolecular damage, as well as the cytotoxic properties of the extracts on the K562 and Jurkat leukemic cell lines. The identification of metabolites was done by liquid chromatography coupled with mass spectrometry. The antioxidant activities were investigated by direct ABTS•+ and DPPH• radical scavenging methods, protection against oxidative damage in proteins and DNA. The cytotoxic properties were investigated against healthy cells, isolated from human peripheral blood (PBMC) and leukemic cell lines. The leaf extract contains catechin, rutin, epigallocatechin derivatives, kaempferol glycosides, luteolin, and dimeric and trimeric procyanidins, while the root extract profile shows obtusichromoneside derivatives, 2-methoxystypandrone, stilbene derivatives, naphthopyranones, and flavanone derivatives. The extracts showed antioxidant activity, with IC50 of 4.86 ± 0.51 µg/mL and 8.33 ± 0.90 µg/mL in the ABTS assay for ELSR and ERSR, respectively. And in the DPPH• assay, the IC50 was 19.98 ± 1.96 µg/mL for ELSR and 13.37 ± 1.05 µg/mL for ERSR. The extracts protected macromolecules against oxidative damage at concentrations of 5 µg/mL. The cytotoxicity test against leukemic strains was observed after 24 and 48 hours of treatment. After 48 h, results against the K562 cell line demonstrate IC50 of 242.54 ± 2.38 µg/mL and 223.00 ± 2.34 µg/mL for ELSR and ERSR , respectively. While against the Jurkat cell line, these extracts showed IC50 of 171.45 ± 2.25 µg/mL and 189.30 ± 2.27 µg/mL, respectively Results on PBMC viability, demonstrate that the extracts showed selectivity for the leukemic cell lines. Together, our results reveal that the leaves and roots of S. rugosa have completely distinct and complex chemical compositions. This study expands the repertoire of identified chemical compounds and underscores their significant pharmacological potential in conditions related to oxidative stress and leukemia.

Working Paper ARTICLE

Let the Dice play God

Damiano Anselmi

Subject: Arts And Humanities, Philosophy Keywords: Determinism; Uncertainty principle; Quantum mechanics; Chance

Online: 23 December 2019 (12:14:01 CET)

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Preprint REVIEW | doi:10.20944/preprints202402.1148.v1

A Review on the Promising Antibacterial Agents in Bone Cement-from Past to Current Insights

Hao Lin, Zhe Gao, Ayakuzi Asilebieke, Rui Guo, Yu-chen Kan, Zhi Wang, Lu-yang Han, Wen-han Bo, Long-xu Han, Yan-yu Qi, Yang Xu, Fang He, Jian-jun Chu

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: bone cement; antibiotic; antibacterial agent; antimicrobial peptide; N-halamine; antimicrobial enzyme

Online: 20 February 2024 (13:32:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints201803.0098.v1

Active Return-to-Center Control Based on Torque and Angle Sensors for Electric Power Steering Systems

Pan-Pan Du, Hao Su, Gong-You Tang

Subject: Engineering, Automotive Engineering Keywords: electric power steering systems; torque sensor; angle sensor; state switch; active return-to-center control

Online: 14 March 2018 (04:43:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.0824.v1

Optimization of Quartz Sand Enhanced Coagulation for Sewage Treatment by Response Surface Methodology

Zhengan Zhang, Yepu Li, Yongzhi Liu, Yuying Li, Zonghua Wang, Dayang Wang, Lu Yan, Jiayin Zhao, B. Larry Li

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: quartz sand; coagulation; response surface methodology; turbidity; polyaluminum chloride

Online: 13 June 2024 (03:16:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2430.v2

The Health Consequences of Plastic Milk Packaging: A Emphasis on Cancer

Abhinandan Patil, Janvi Rathi

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: plastic; milk; carcinogenic substances; human health

Online: 15 August 2024 (10:22:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202006.0064.v1

Why Risk It? Athletes' Return to Sport Decisions Following Concussion Injuries: A Pilot Study

Victoria Waterworth, Alexander Procyk, Elisa Canetti, Wayne Hing, Suzanne Gough

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: traumatic brain injury; return to play; risk aversion; choice behaviour; health

Online: 7 June 2020 (07:51:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0297.v1

Change Through Play, Rethinking Masculinity: An Intervention to Gun Violence in the United States

Helena Baffoe

Subject: Social Sciences, Safety Research Keywords: Gun violence; intervention; Change Through Play; Perception; Safety; United State

Online: 5 June 2024 (15:31:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints202009.0133.v1

Mens sana in corpore sano: Does the Glycemic Index Have a Role to Play?

Lionel Carneiro, Corinne Leloup

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Cognition; nutrition; metabolism; neurodegeneration; ketone bodies; glycaemia; nutrition therapy

Online: 5 September 2020 (08:29:52 CEST)

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Preprint SHORT NOTE | doi:10.20944/preprints202404.0015.v1

The significance of AI in the Future of Healthcare Diagnostics and Treatments

Abhinandan Patil

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Artificial intelligence; pathology; cardiology; cancer; radiology

Online: 1 April 2024 (17:02:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0074.v1

miR-30a as Potential Therapeutic by Targeting TET1 through Regulation of the Hydroxymethlation of Drp-1 Promoter in IPF

Songzi Zhang, Huizhu Liu, Yuxia Liu, Jie Zhang, Hongbo Li, Weili Liu, Guohong Cao, Pan Xu, Jinjin Zhang, Changjun Lv, Xiaodong Song

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: idiopathic pulmonary fibrosis; miR-30a; TET1; Drp-1

Online: 16 January 2017 (04:44:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0234.v1

Demographic Variables Impact on Individual Investment Return

Md. Fazlul Huq Khan, Fakrul Ahmed

Subject: Business, Economics And Management, Finance Keywords: Stock Market; Individual return; Bangladesh

Online: 16 March 2022 (14:26:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints201812.0152.v1

Electromagnetic Fields of Lightning Return Strokes-Revisited

Vernon Cooray, Gerald Cooray

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Electromagnetic fields, return strokes, dipole fields, accelerating charges, radiation fields, static fields, velocity fields

Online: 12 December 2018 (15:21:10 CET)

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Preprint REVIEW | doi:10.20944/preprints202005.0203.v1

Evidence Based Suggestions for the Return to Elective Urology Surgery Following the COVID-19 Pandemic

Sarkhell Radha, Irrum Afzal, Stella Vig

Subject: Public Health And Healthcare, Health Policy And Services Keywords: urology; COVID-19; return to elective services

Online: 12 May 2020 (05:41:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1383.v1

Interscapular Pain after Anterior Cervical Discectomy and Fusion: Does Zygapophyseal Joints over Distraction Play a Role?

Luca Ricciardi, Daniele Bongetta, Amedeo Piazza, Nicolò Norri, Antonella Mangraviti, Sokol Trungu, Evaristo Belli, Luca Zanin, Giorgio Lofrese

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: ACDF; rehabilitation; postoperative pain; complications; prosthesis; cervical spine; disc herni-ation; myelopathy; cervicalgia.

Online: 22 March 2024 (13:09:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0453.v1

Detection of Novel Biomarkers in Saliva of Rheumatoid Arthritis Model Mice by Proteomics and Pathological Analysis

Wakako Sakaguchi, Juri Saruta, Shinya Fuchida, Yuko Yamamoto, Masahiro To, Tomoko Shimizu, Mayumi Yakeishi, Keiichi Tsukinoki

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: anti-citrullinated protein antibody (ACPA); alpha-1-antitrypsin (A1AT); DBA/1JJmsSlc mice Proteome analysis; rheumatoid arthritis (RA)

Online: 28 December 2021 (14:44:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0251.v1

Play, Flow and Wonder – Reassessing the Notion of Optimal Experience

Jesper Falck Legaard

Subject: Arts And Humanities, Humanities Keywords: Play; Flow; Design; Wonder; Toys

Online: 14 December 2022 (06:57:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.2130.v1

Emergency Animal Boarding: A Social Return on Investment

Gemma Catherine Ma, Jioji Ravulo, Ursula McGeown

Subject: Social Sciences, Other Keywords: Companion animal; dog; cat; human-animal bond; Social Return on Investment; animal shelter; animal welfare

Online: 30 May 2023 (11:34:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0322.v1

The (big) Role of Family Constellations in Return Migration and Transnationalism

Bresena Kopliku, Elvisa Drishti

Subject: Social Sciences, Geography, Planning And Development Keywords: Albania; family; migration; return; transnationalism

Online: 21 July 2022 (10:45:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0513.v1

Immunogenicity Evaluation of Respiratory Syncytial Virus Prefusogenic-F Based Virus-like-Particles Consisting of G and M Proteins in Mice

Ahmedali S. Mandviwala, Archana Kulkarni Munje, Anke L.W. Huckriede, Vidya A. Arankalle, Harshad P. Patil

Subject: Biology And Life Sciences, Virology Keywords: respiratory syncytial virus (RSV); virus-like particles (VLPs); prefusogenic F; glycoprotein; matrix protein; vaccine

Online: 8 April 2024 (08:37:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.0916.v1

Biochar from Lignocellulosic Biomass: The Importance of Physicochemical Characterization and Multi-Criteria Decision Analysis for Its Applications

Rafael Benjamin Evaristo, Romulo C Dutra, Paulo Anselmo Suarez, Grace Ferreira Ghesti, Edgar Silveira

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: biochar; pyrolisis; thermochemical process; characterization; biomass

Online: 15 April 2024 (07:28:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1501.v1

X-ray Microtomography Analysis of Integrated Crop-Livestock Production Impact on Soil Pore Architecture

José V. Gaspareto, Luiz Fernando Pires

Subject: Environmental And Earth Sciences, Soil Science Keywords: Computed tomography; Image analysis; Minimum tillage; No-tillage; Soil structure; Soil management; Soil porous structure

Online: 23 May 2024 (07:35:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0194.v1

Determination of Nine Fentanyl and Six Amphetamine Drugs in Hair Samples by GC-MS/MS and LC-MS/MS

Qi Wei, Fuhai Su

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Fentanyl; Amphetamine; Hair samples; Reference material; GC-MS/MS; LC-MS/MS

Online: 3 September 2024 (07:30:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0557.v1

Clinical Significance of Whole-Body Computed Tomography Scans in Pediatric Out-of-Hospital Cardiac Arrest Patients Without Prehospital Return of Spontaneous Circulation

Masanori Ishida, Taro Tanaka, Shinichiro Morichi, Hirotaka Uesugi, Haruka Nakazawa, Shun Watanabe, Motoki Nakai, Gaku Yamanaka, Hiroshi Homma, and Kazuhiro Saito

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: computed tomography; pediatric patient; out-of-hospital cardiac arrest; return of spontaneous circulation

Online: 6 September 2024 (16:53:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1191.v1

Systematic Review of Machine Learning Return-on-Investment Forecasting

Nancy Chen

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Machine Learning; Latent Semantic Analysis; Gradient Boosting; Random Forest; Logistic Regression

Online: 16 July 2024 (05:34:01 CEST)

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Preprint REVIEW | doi:10.20944/preprints202007.0528.v1

In Vitro or in Vivo Models, the Next Frontier for Unraveling Interactions between Malassezia spp. and Hosts. How Much do We Know?

Maritza Torres, Hans De Cock, Adriana Marcela Celis Ramírez

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: In vitro; in vivo; animal model; Malassezia; infection; host-pathogen interaction; Galleria mellonella

Online: 22 July 2020 (11:34:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202112.0230.v1

Return to the New Normal: Empirical Analysis of Changes in E-consumer Behavior During the COVID-19 Pandemic

František Pollák, Peter Markovič, Roman Vavrek, Michal Konečný

Subject: Business, Economics And Management, Marketing Keywords: e-commerce; m-commerce; innovation; business management; COVID-19; Czech Republic; Facebook

Online: 14 December 2021 (11:51:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0607.v1

Affective Neuroscience and Sex Differences in the Relationship between Anger and Fear. If Fear Increases, Seeking and Play Decrease, in the Female Sample.

Paola Manfredi

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Sex differences; basic affective systems; SEEKING; FEAR; ANGER; PANIC; PLAY; CARE; gender inequality

Online: 8 August 2024 (12:05:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0710.v1

Microstructures and Corrosion Properties of Wire Arc Additive Manufactured Copper-Nickel Alloys

Jie Song, Xavier A. Jimenez, Albert C To, Yao Fu

Subject: Engineering, Other Keywords: 70/30 copper-nickel; wire arc additive manufacturing; dendritic feature; chemical segregation; corrosion properties; sodium chloride solution

Online: 9 January 2024 (09:19:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints201905.0306.v1

Intraday Return Reversals: Empirical Evidence from the Korean ETF Market

Sangki Lee, Chung-hun Hong

Subject: Business, Economics And Management, Finance Keywords: return reversals; exchange-traded funds (ETFs); attention hypothesis; disagreement hypothesis; short selling

Online: 27 May 2019 (09:53:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1281.v1

A Preliminary Observational Study of the Endoscopic Anatomical Structures of the Lumbar Spine Through the Foraminal and the Interlaminar Approach

Chuanchao Du, Kunfeng Song, Xiaoguang Liu, Ulrich Zils, Satishchandra Gore, Jincai Yang

Subject: Medicine And Pharmacology, Surgery Keywords: ; lumbar endoscopic surgery; transforaminal; interlaminar; endoscopic anatomy structure ;

Online: 16 July 2024 (08:51:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.2078.v1

The Role of Strength-Related Factors on Psychological Readiness for Return to Sport following Anterior Cruciate Ligament (ACL) Reconstruction

Oliver Lee, Mark A Williams, Clare D Shaw, Anne Delextrat

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: angle-specific torque; rate of force development; time since surgery; rehabilitation

Online: 30 August 2023 (11:19:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0921.v1

Wave and Tidal Energy: A Patent Landscape Study

Mohamadreza Pazhouhan, Amin Karimi Mazraeshahi, Mohammad Jahanbakht, Kourosh Rezanejad, Mohammad H. Rohban

Subject: Engineering, Marine Engineering Keywords: Wave Energy; Tidal Energy; Patent Analysis; Topic Modeling; Large Language Models; BERTopic

Online: 11 September 2024 (16:17:03 CEST)

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Preprint REVIEW | doi:10.20944/preprints202107.0132.v1

Perceived Barriers and Facilitators of Adventurous Play in Schools: A qualitative systematic review

Rachel J Nesbit, Charlotte L Bagnall, Kate Harvey, Helen F Dodd

Subject: Social Sciences, Psychology Keywords: child; play; risky play; adventurous play; school; qualitative synthesis

Online: 6 July 2021 (11:27:45 CEST)

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Working Paper REVIEW

How the Biofertilizers Play a Role in the Regulation and Sustainability of Agriculture

Muhammad Salman Akram, Muhammad Abubakar Cheema, Muhammad Waqas, Muhammad Bilal, Muhammad Saeed

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: biofertilizers; PGPR; Auxin; Rhizobium

Online: 31 August 2020 (08:12:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0239.v1

Plug-and-Play Solutions for Energy-Efficiency Deep Renovation of European Building Stock

Rizal Sebastian, Anna Gralka, Rosamaria Olivadese, Marco Arnesano, Gian Marco Revel, Timo Hartmann, Christoph Gutsche

Subject: Engineering, Architecture, Building And Construction Keywords: energy-efficient buildings; deep renovation; Plug-and-Play (PnP); building information modelling (BIM); building energy modelling (BEM)

Online: 14 August 2018 (03:59:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0182.v1

Immobile Charges Play an Essential Role for Membrane Potential Generation

Hirohisa Tamagawa, Bernard Delalande

Subject: Biology And Life Sciences, Biophysics Keywords: membrane potential; membrane theory; Association-Induction Hypothesis; membrane permeability; ion adsorption

Online: 2 February 2024 (16:37:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0646.v1

Classification of Google Play Store Application Reviews Using Machine Learning

Abdul Karim, Azhari Azhari, Meshrif Alruily, Hamza Aldabbas, Samir Brahim Belhaouri, Ali Adil Qureshi

Subject: Computer Science And Mathematics, Computer Science Keywords: Machine Learning; Natural Language Processing; Text Mining; Semantic Analysis; Scraping; Google Play Store; Rating

Online: 26 July 2020 (17:11:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1792.v1

Neutrophils Expressing Programmed Death-Ligand 1 Play an Indispensable Role in Effective Bacterial Elimination and Resolving Inflammation in Methicillin-Resistant Staphylococcus aureus Infection

Azusa Terasaki, Faizan Ahmed, Alato Okuno, Zhenzi Peng, Duo-Yao Cao, Suguru Saito

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: PD-L1, neutrophil, MRSA, PD-1, immunosuppressive

Online: 29 March 2024 (09:15:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1983.v1

Artificial Intelligence Usage in Game Development

DHANAMMA JAGLI, Subhashchandra Nalla, Srinivasrao Danikonda, Laxmi Nakirekanti

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Artificial intelligence; Game experience; Machine learning

Online: 27 June 2024 (16:55:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.0806.v1

Running Return of Service Schemes in Southern Africa: Lessons from Botswana, Eswatini and Lesotho

Sikhumbuzo A. Mabunda, Andrea Durbach, Wezile W. Chitha, Oduetse Moaletsane, Blake Angell, Rohina Joshi

Subject: Public Health And Healthcare, Health Policy And Services Keywords: health system; health workforce; human resources; health policy; bursary

Online: 23 April 2023 (14:22:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1885.v1

Numerical and Performance Analysis of R290 Heat Pump Driven Air Conditioning System for Heating and Cooling

Subhash Kumar, V N Raibhole, Premendra Janardan Bansod, AKHYA KUMAR BEHERA

Subject: Engineering, Mechanical Engineering Keywords: COP; Heat Pump; R290; GWP; ODP

Online: 24 July 2024 (14:02:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0249.v1

Machine Learning Algorithm’s Measurement and Analytical Visualization of User’s Reviews for Google Play Store

Abdul Karim, Azhari Azhari, Samir Brahim Belhaouri, Ali Adil Qureshi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; preprocessing; semantic analysis; text mining; TF/IDF; scraping; Google Play Store

Online: 11 August 2020 (08:14:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0621.v1

Advanced NMR, FT-IR, UV-VIS and XRD Methods Used for Characterization of Organo-Mineral Fertilizers Based on Biosolids

Ramona Crainic, Nagy Mihaela Elena, Fodorean Gabriel, Vasilescu Mihai, Pascuta Petru, Popa Florin, Radu Fechete

Subject: Environmental And Earth Sciences, Soil Science Keywords: Biosolids; organo-mineral fertilizers; 1H NMR relaxometry and double-quantum, 1H and 13C NMR, FT-IR and UV-VIS spectroscopy, PCA statistical analysis; machine learning predictions.

Online: 11 June 2024 (09:54:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1439.v1

Global Trends in Breast Cancer Research: A Bibliometric Analysis from the Scopus Database (2014–2023)

Vishwas Hase, Ahirrao Manjusha

Subject: Social Sciences, Library And Information Sciences Keywords: Brest Cancer; Scientometrics; Bibliometrics; Cancer; Scopus

Online: 18 September 2024 (14:26:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1883.v1

Nozzle Design of Plug-and-Play Passive Pre-chamber Ignition Systems for Natural Gas Engines

Wei Li, Junfang Ma, Tao Zhu, Haiqiao Wei, Jiaying Pan

Subject: Engineering, Energy And Fuel Technology Keywords: Natural gas engine; Turbulent jet ignition; Pre-chamber; Scavenging; Fuel consumption

Online: 28 June 2023 (02:17:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1071.v1

Collaborative Semantic Annotation Tooling (CoAT) to Improve Efficiency and Plug-and-Play Semantic Interoperability in Secondary Use of Medical Data: Concept, Implementation, and First Cross-Institutional Experiences

Thomas Wiktorin, Daniel Grigutsch, Felix Erdfelder, Andrew J. Heidel, Frank Bloos, Danny Ammon, Matthias Löbe, Sven Zenker

Subject: Computer Science And Mathematics, Software Keywords: semantic annotation; medical data; annotation tool; terminology; SNOMED CT; LOINC; ATC; interoperability; reusability

Online: 15 January 2024 (06:20:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints201901.0200.v1

Water Availability Assessment of Shale Gas Production in the Weiyuan Play, China

Xia Wu, Xia Jun, Baoshan Guan, Xinming Yan, Lei Zou, Ping Liu, Lifeng Yang, Si Hong, Sheng Hu

Subject: Environmental And Earth Sciences, Environmental Science Keywords: water availability; shale gas; water sustainability; Weiyuan play

Online: 21 January 2019 (08:59:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.1684.v1

Research on the Evolution of Urban Spatial Structure in Xi'an Based on Historical Maps and GIS Technology

Dawei Yang, Xiaodong Liu, Huangyang Yang

Subject: Arts And Humanities, History Keywords: Historical Maps; GIS; Xi'an; Urban Spatial Structure; Evolution

Online: 23 September 2024 (12:17:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0472.v1

Sentiment Analysis of Current Reports Texts with Use of Cumulative Abnormal Return and Deep Neural Network

Maciej A. Wujec

Subject: Business, Economics And Management, Economics Keywords: fundamental analysis supported by machine learning; financial texts sentiment analysis; natural language processing in finance

Online: 28 September 2021 (12:38:54 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202409.1295.v1

The Escalating Antibiotic Crisis in Nigeria: A Violation of Human Rights and Ethical Imperatives – Commentary

Ifeanyichukwu Akuma, Elizabeth Igba Chimezie, Aminu Hashidu Danjuma

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Antibiotic crisis; healthcare access; pharmaceutical pricing; regulatory challenges; ethical obligations

Online: 17 September 2024 (12:03:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0279.v1

The Role of Energy Return for Energy Invested (EROEI) in Dissipative Autocatalytic Systems

Ugo Bardi, Alessandro Lavacchi, Ilaria Perissi

Subject: Engineering, Energy And Fuel Technology Keywords: EROEI; Lotka Volterra; resource exploitation; dissipative systems

Online: 19 October 2021 (13:57:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202004.0459.v1

Influence of Overcrowding in the Emergency Department on Return Visit within 72 Hours

Dong-uk Kim, Yoo Seok Park, Joon Min Park, Nathan J. Brown, Kevin Chu, Ji Hwan Lee, Ji Hoon Kim, Min Joung Kim

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: emergency department; crowding; return visit; admission; patient satisfaction; quality of healthcare

Online: 25 April 2020 (10:45:25 CEST)

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Preprint REVIEW | doi:10.20944/preprints202002.0099.v1

The Determination of HIV-1 RT Mutation Rate, Its Possible Allosteric Effects, and Its Implications on Drug Resistance

Joshua Yi Yeo, Ghin Ray Goh, Chinh Tran-To Su, Samuel Ken-En Gan

Subject: Biology And Life Sciences, Virology Keywords: retroviruses; HIV-1; reverse transcriptase; mutation rate; drug resistance, allostery

Online: 7 February 2020 (11:50:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints201805.0207.v1

Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding

Chinh Tran-To Su, Wai-Heng Lua, Wei-Li Ling, Samuel Ken-En Gan

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: antibody; Isotype IgA; Pertuzumab; allosteric; biologics; constant region; variable region

Online: 15 May 2018 (07:51:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2034.v1

Does Iodine Intake Play a Role in Modifying the Relationship between Maternal Dysglycemia and Birth Weight?

Yaniv S. Ovadia, Dov Gefel, Yoel Toledano, Shani Rosen, Yael Avrahami-Benyounes, Ludmila Groisman, Efrat Rorman, Lihi Hen, Shlomo Fytlovich, Liora S Katz, Eyal Y Anteby, Simon Shenhav

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: iodine deficiency; glucose challenge test; large for gestational age; thyroglobulin; io-dine-containing supplements; maternal dysglycemia

Online: 30 May 2023 (04:08:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints201907.0286.v1

Reviewing HIV-1 Gag Mutations in Protease Inhibitors Resistance: Insights for Possible Novel Gag Inhibitor Designs

Chinh Tran-To Su, Darius Wen-Shuo Koh, Samuel Ken-En Gan

Subject: Biology And Life Sciences, Virology Keywords: HIV-1 Gag; Gag inhibitors; Protease; Protease inhibitors; drug resistance mutations; drug design

Online: 25 July 2019 (10:05:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.0054.v1

Play Behavior as a Positive Welfare Indicator for Farmed Spotted Paca (Cuniculus paca)

Allison Ferreira de Lima, Stella Guedes Calazans Lima, Sérgio L G Nogueira-Filho, Suzanne D. E. Held, Michael Mendl, Selene Siqueira da Cunha Nogueira

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: animal welfare; applied ethology; animal emotions; farmed animals; play behavior; positive welfare indicator

Online: 1 November 2023 (10:34:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0567.v1

Investigating Hydrological Drought Characteristics and Different Return Periods in Semi-Arid Regions under CMIP5 Climate Change Scenarios

Sornsawan Chatklang, Piyapong Tongdeenok, Naruemol Kaewjampa

Subject: Environmental Science, Environmental And Earth Sciences Keywords: climate change; CMIP5; Hydrological Drought Characteristics; Streamflow Drought Index (SDI)

Online: 8 August 2024 (12:05:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202011.0510.v1

The Return of Wooded Landscapes in Wales: An Exploration of Possible Post-Brexit Futures.

Syed Amir Manzoor, Geoffrey Griffiths, David Christian Rose, Martin Lukac

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Brexit; land use change; Wales; agricultural policies; forestry

Online: 19 November 2020 (12:24:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints201809.0474.v1

The R^2 and the Seven Events in Hong Kong: A New Look at Return Synchronicity and Price Efficiency

Jinghan Cai, Fengyun Li, Iordanis Petsas

Subject: Business, Economics And Management, Finance Keywords: price efficiency; R2; Hong Kong stock market data

Online: 25 September 2018 (04:13:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1822.v1

A Situation Analysis of the Capacity of Laboratories in Zambia to Conduct Surveillance of Antimicrobial Resistance: Strengths, Weaknesses, Opportunities, and Challenges

Doreen Mainza Shempela, Steward Mudenda, Maisa Kasanga, Victor Daka, Mundia Hendrix Kangongwe, Mapeesho Kamayani, Jay Sikalima, Baron Yankonde, Cynthia Banda Kasonde, Ruth Nakazwe, Andrew Mwandila, Fatim Cham, Michael Njuguna, Bertha Simwaka, Linden Morrison, Joseph Yamweka Chizimu, John Bwalya Muma, Roma Chilengi, Karen Sichinga

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: antimicrobial resistance; bacteriology; laboratory capacity; surveillance; Zambia

Online: 28 May 2024 (09:59:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1511.v1

Stress as a Catalyst: Understanding its Role in Bowel Cancer

Abhinandan Patil, Neha Singh

Subject: Biology And Life Sciences, Other Keywords: stress; bowel; tumors; psychology

Online: 26 March 2024 (11:53:39 CET)

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Preprint REVIEW | doi:10.20944/preprints202109.0145.v1

Directed Medical Role Play for Children: Review of the Teddy Bear Hospital Implementations, Objectives, and Reported Experiences

Reem Jazrawy, Sharon Mascarenhas, Youness Zidoun, Nabil Zary

Subject: Social Sciences, Education Keywords: Role-play; medical roleplay; teddy bear hospital; teddy bear clinic

Online: 8 September 2021 (11:54:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1556.v1

The Impact of Value Creation (Tobin’s Q), Total Shareholder Return (TSR), and Survival (Altman’s Z) on Credit Ratings

Nazario Augusto Oliveira, Leonardo Fernando Cruz Basso

Subject: Business, Economics And Management, Finance Keywords: credit rating; credit risk; determinants; risk management

Online: 26 March 2024 (13:10:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints201712.0075.v1

Measuring the Magnetic Flux Density with Flux Loops and Hall Probes in the CMS Magnet Flux Return Yoke

Benoit Curé, Vyacheslav Klyukhin, Nicola Amapane, Austin Ball, Andrea Gaddi, Hubert Gerwig, Alain Hervé, Richard Loveless, Martijn Mulders

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: electromagnetic modeling; flux loops; Hall effect devices; magnetic field measurement; magnetic flux density; measurement techniques; superconducting magnets

Online: 12 December 2017 (09:07:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0112.v1

Computational Elucidation of Human β-defensin-2 as a Dual Inhibitor of MMP-9 and PKC-βII for Diabetic Wound Management

Vidyasrilekha Sanapalli, Dilep Kumar. Sigalapalli, Afzal B. Shaik, Richie R. Bhandare, Bharat Kumar Reddy Sanapalli

Subject: Medicine And Pharmacology, Dermatology Keywords: Diabetic wound; Human β -defensin-2; Matrix metalloproteinase-9; Protein kinase C-β II; Protein-protein docking; Molecular dynamics simulation studies

Online: 2 September 2024 (13:35:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints202409.1683.v1

Resistome Mapping in Foodborne Pathogens: Understanding Role in the Transmission Dynamics of Resistance Genes

Muneer Oladipupo Yaqub, Chinedu Eucharia Joseph, Aashika Jain, Lekshmi K. Edison

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: antibiotic resistance genes (ARGs); horizontal gene transfer (HGT); metagenome sequencing; whole genome sequencing; antibiotic stewardship; food safety

Online: 23 September 2024 (12:10:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0374.v2

Detection of Meteoritic Amino Acids in Extremely Small Sample Sizes: Implications for Sample Return Missions

Christian Potiszil, Masahiro Yamanaka, Tsutomu Ota, Ryoji Tanaka, Katsura Kobayashi, Eizo Nakamura

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Carbonaceous chondrite; sample return; amino acid; ultrahigh performance liquid chromatography; Orbitrap-mass spectrometry; organic matter; astrobiology; origin of life

Online: 20 March 2023 (04:36:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1072.v1

Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics – Pilot Study

Pamella de Barros Motta, Marcela Leticia Leal Gonçalves, Juliana Maria Altavista Sagretti Gallo, Ana Paula Taboada Sobral, Lara Jansiski Motta, Elaine Marcílio Santos, David José Casimiro de Andrade, Cinthya Cosme Gutierrez Duran, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Anna Carolina Ratto Tempestine Horliana, Sandra Kalil Bussadori

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: halitosis; microbiome; antimicrobial photodynamic therapy; probiotics.

Online: 19 February 2024 (16:13:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.2306.v2

Ethylene-Di-Amine Modified β-Cyclodextrin Catalyzed Green Synthesis of Pyrimidones and Its In Silico Study against ESBL E. coli Receptor

Manojkumar Rajapriyan, Mohammed M. Alanazi, R Imran Khan, Ajmal R. Bhat, Syed Ali Padusha M, Sarkar M. A. Kawsar, Javed Masood Khan, Ayyiliath M Sajith

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Ethylene-di-amine modified β -CD; Multicomponent reaction; 3,4-dihydropyrimidin-2(1H)-ones DHPM derivatives; Solvent-free conditions; Reusability

Online: 2 April 2024 (10:58:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2162.v1

Corporate Social Responsibility and Return: Social Impact a Case Study of an Emerging Market Oil Industry in Stock Exchange.

Edmundo Lizarzaburu, Kurt Burneo, Conrado Diego García-Gómez

Subject: Social Sciences, Government Keywords: oil industry; corporate social responsibility; emerging market; social impact; case study

Online: 31 May 2023 (03:13:24 CEST)

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