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Preprint ARTICLE | doi:10.20944/preprints202308.0983.v1

Brain Tumor Detection using the VGG-16 Model: A Deep Learning Approach

Dheiver Santos

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: brain tumor detection; VGG-16 model; convolutional neural network; MRI imaging; deep learning

Online: 14 August 2023 (08:34:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.0848.v1

The Logistical Backbone of Visual Function: Complementary Function of Dietary Vitamin A Receptors and Rhodopsin Transporters

Matthias Leung, Jeremy Steinman, Dorothy Li, Anjelynt Lor, Andrew Gruesen, Ahmed Sadah, Frederik J. Van Kuijk, Sandra Montezuma, Altaf A. Kondkar, Rakesh Radhakrishnan, Glenn P. Lobo

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Vitamin A; RBP4; RBPR2; STRA6; MYO1C; MYO7A; Photoreceptor; Rhodopsin; Visual Function

Online: 14 March 2024 (15:08:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0046.v1

Visual Symmetry: From Geometry to Sensation and Preference

Birgitta Dresp-Langley

Subject: Social Sciences, Cognitive Science Keywords: visual symmetry; affine projection; fractals; visual sensation; aesthetics; preference

Online: 5 August 2016 (05:15:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202101.0550.v1

Customizable Vector Acceleration in Extreme-Edge Computing: A RISC-V Software/Hardware Architecture Study on VGG-16 Implementation

Mauro Olivieri, Abdallah Cheikh, Francesco Menichelli, Antonio Mastrandrea, Stefano Sordillo

Subject: Engineering, Automotive Engineering Keywords: edge-computing; processors; hardware acceleration

Online: 27 January 2021 (09:59:46 CET)

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Preprint REVIEW | doi:10.20944/preprints201809.0247.v1

Group entropies: from phase space geometry to entropy functionals via group theory

Henrik Jeldtoft Jensen, Piergiulio Tempesta

Subject: Physical Sciences, Thermodynamics Keywords: Phase space volume, formal group theory, entropy

Online: 13 September 2018 (16:08:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.2001.v1

The Brain Region Specific Citrullinome and PAD 1-6 Isozyme Detection in a Pre-motor Parkinson’s Disease Rat Model

Audrey Mercer, Marco Sancandi, Amy Maclatchy, Sigrun Lange

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: peptidylarginine deiminase (PAD); citrullination/deimination; Parkinson’s disease; brain; cortex; hippocampus; midbrain; striatum; cerebellum; olfactory bulb; KEGG

Online: 28 June 2024 (10:50:47 CEST)

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The detection of early biomarkers and molecular mechanisms in Parkinson’s disease (PD) remains a challenge. Recent research has pointed to potential roles for peptidylarginine deiminases (PADs), a family of calcium activated enzymes, and associated post-translational protein citrul-lination/deimination in early stages of the disease, with a focus on hippocampal and cortex re-gions of the brain. Further analysis of brain region specific changes in PAD isozymes and identi-fication of brain-region specific citrullinomes, therefore remain to be studied. This study assessed brain-region specific PAD isozyme expression (PADs 1-4; PAD6) and associated citrullinated protein targets in the 6-hydroxydopamine (6-OHDA) induced rat model of pre-motor PD. Cortex, hippocampus, striatum, midbrain, cerebellum and olfactory bulb were compared between con-trols/shams and the PD model. In cortex, a significant increase of PAD2 and PAD3 was observed in the PD model. In hippocampus, PAD3, PAD4 and PAD6 showed strongest levels, but with no significant changes observed between PD and controls. In striatum, a significant reduction in all PAD isozymes was observed in the PD model. In the olfactory bulb, PAD3 was significantly el-evated in PD. In midbrain, PAD2, PAD4 and PAD6 showed strongest signal but with no signifi-cant changes between PD and controls. In cerebellum, a significant increase was seen in PAD3, PAD4 and PAD6 in the PD model. Citrullinated protein hits were most abundant in cortex and hippocampus, while for the PD model an increase in citrullinated hits was particularly observed in cortex and cerebellum, compared to controls. For all brain regions there was a considerable difference in citrullinated protein IDs between the PD model and the controls. Citrullinome as-sociated KEGG pathways differed in the six brain regions; some were overlapping for controls and PD, some were identified for the PD model only, and some were identified in control brains only. KEGG pathways identified in PD brains onlywere: “Axon guidance”; “Spinocerebellar ataxia”; “Hippo signalling pathway”; “NOD-like receptor signalling pathway”; “Phosphatidyl-inositol signalling system”; “Rap1 signalling pathway”; “Platelet activation”; “Yersinia infection”; “Fc gamma R-mediated phagocytosis”; “Human cytomegalovirus infection”; “Inositol phosphate metabolism”; “Thyroid hormone signalling pathway”; “Progesterone-mediated oocyte matura-tion”; “Oocyte meiosis”; and “Choline metabolism in cancer”. Our findings highlight differences in PAD isozymes, citrullinated proteins and associated KEGG pathways between brain regions, in pre-motor PD.

Preprint ARTICLE | doi:10.20944/preprints202402.0339.v1

A Crucial Role of Proteolysis in Formation of Intracellular Dinitrosyl Iron Complexes

Karolina E. Wójciuk, Jarosław Sadło, Hanna Lewandowska, Marcin Kruszewski

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: K562 cells; electron paramagnetic resonance; nitric oxide; reactive nitrogen species; dinitrosyl iron complexes; chelatable iron; glutathione

Online: 6 February 2024 (13:33:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.1213.v1

Autocatalytic Sets And Assembly Theory: A Toy Model Perspective

Sebastian Raubitzek, Alexander Schatten, Philip König, Edina Marica, Sebastian Eresheim, Kevin Mallinger

Subject: Computer Science And Mathematics, Mathematical And Computational Biology Keywords: Assembly Theory; Autocatalytic Sets; Complexity; Formation of Molecules; Origin of Life; Autocatalysis

Online: 16 August 2024 (09:49:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1427.v1

Study of Femtosecond Laser Ablation and Polishing Process on 4H-SiC Substrate

Ziqiang Zhao, Lin Zhao, Yun Peng

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: femtosecond laser; simulation; surface polish

Online: 22 May 2024 (11:07:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.1007.v1

CAR-NK Cell Therapy: A Transformative Approach to Overcoming Oncological Challenges

Wangshu Li, Xiuying Wang, Xu Zhang, Aziz ur Rehman Aziz, Daqing Wang

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: CAR-NK cell therapy; Immunotherapy; tumor heterogeneity

Online: 18 June 2024 (11:52:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0941.v1

Electrolyte Imbalance in Acute Traumatic Brain Injury: Insights from the First 24 Hours

Alina Săcărescu, Mihaela-Dana Turliuc

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: traumatic brain injury; electrolytes; early monitoring; Glasgow Coma Scale; chloride; potassium

Online: 13 August 2024 (14:39:41 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.0484.v1

A Review on Key Technologies and Developments of Hydrogen Fuel Cell Multi-rotor Drones

Zenan Shen, Shaoquan Liu, Wei Zhu, Daoyuan Ren, Yu Feng, Qiang Xu

Subject: Engineering, Energy And Fuel Technology Keywords: hydrogen fuel cell; multi-rotor drone; lightweight design; hydrogen storage method; energy management strategy

Online: 8 February 2024 (05:20:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0736.v1

Tea Grounds as a Waste Biofiller for Natural Rubber

Aleksandra Juszkiewicz, Magdalena Maciejewska

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: tea grounds; natural rubber; tea waste; biofiller; ionic liquids

Online: 13 March 2024 (11:56:26 CET)

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Preprint REVIEW | doi:10.20944/preprints202408.1744.v1

Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface

Brian Juin Hsien Lee, Kai Yuan Tey, Ezekiel Ze Ken Cheong, Qiu Ying Wong, Si Qi Chua, Marcus Ang

Subject: Medicine And Pharmacology, Ophthalmology Keywords: Anterior Segment; Cornea; Ocular Surface; Optical Coherence Tomography Angiography

Online: 26 August 2024 (11:08:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0074.v1

Diversity of HPV 16 L1 in the Asian Region: A Comparative Analysis of Sequences

Rana Özdoğan, Muharrem Okan Çakır, G Hossein Ashrafi, Uğur Bilge

Subject: Biology And Life Sciences, Virology Keywords: Human Papillomavirus, HPV 16, L1, Phylogenetic analysis

Online: 3 March 2024 (18:18:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0011.v1

Simulation Analysis of Solution Transportation Absorption Chiller with the Capacity from 25 RT to 1000 RT

Koji Enoki, Fumi Watanabe, Seigo Tanaka, Atsushi Akiwawa, Toshitaka Takei

Subject: Engineering, Energy And Fuel Technology Keywords: absorption chiller; thermal energy transportation; solution transportation; ammonia-water; COP; simulation

Online: 4 February 2017 (07:49:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.1107.v1

Human Pose Estimation for Yoga using VGG-19 and COCO Dataset

Dhadkan Shrestha, Peshal Nepal, Pratik Gautam, Pradeep Oli

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Human Pose Estimation (HPE); Convolutional Neural Network (CNN); VGG-19, Part Affinity Fields (PAFs); COCO Dataset; Real-Time Pose Detection

Online: 20 August 2024 (11:04:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0126.v1

Senior High School Students’ difficulties with Geometry Topics

Christian Kwame Kpotosu, Stanley Amegbor, Bismarck Mifetu, Raymond Bessa Kwadzo Ezah

Subject: Social Sciences, Education Keywords: chord; Circle theorems; geometry; geometry difficulties; geometry topics; senior high schools; tangents; perpendicularity

Online: 2 May 2024 (10:11:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0002.v2

Small UAS-Based Wind Feature Identification System Part 1: Integration and Validation

Leopoldo Rodriguez Salazar, Jose A. Cobano, Anibal Ollero

Subject: Engineering, Control And Systems Engineering Keywords: wind prediction; wind estimation; UAS; wind shear; gust; multi-platform integration

Online: 18 January 2017 (09:44:54 CET)

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This paper presents a system for identification of wind features, such as gusts and wind shear. These are of particular interest in the context of energy-efficient navigation of Small Unmanned Aerial Systems (UAS). The proposed system generates real-time wind vector estimates and a novel algorithm to generate wind field predictions. Estimations are based on the integration of an off-the-shelf navigation system and airspeed readings in a so-called direct approach. Wind predictions use atmospheric models to characterize the wind field with different statistical analyses. During the prediction stage, the system is able to incorporate, in a big-data approach, wind measurements from previous flights in order to enhance the approximations. Wind estimates are classified and fitted into a Weibull probability density function. A Genetic Algorithm (GA) is utilized to determine the shaping and scale parameters of the distribution, which are employed to determine the most probable wind speed at a certain position. The system uses this information to characterize a wind shear or a discrete gust and also utilizes a Gaussian Process regression to characterize continuous gusts. The knowledge of the wind features is crucial for computing energy-efficient trajectories with low cost and payload. Therefore, the system provides a solution that does not require any additional sensors. The system architecture presents a modular decentralized approach, in which the main parts of the system are separated in modules and the exchange of information is managed by a communication handler to enhance upgradeability and maintainability. Validation is done providing preliminary results of both simulations and Software-In-The-Loop testing. Telemetry data collected from real flights, performed in the Seville Metropolitan Area in Andalusia (Spain), was used for testing. Results show that wind estimation and predictions can be calculated at 1 Hz and a wind map can be updated at 0.4 Hz. Predictions show a convergence time with a 95% confidence interval of approximately 30 s.

Preprint ARTICLE | doi:10.20944/preprints201608.0192.v1

Demands of Geometry on Color Vision

Dale Purves, Chidambaram Yegappan

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: trichromacy; opponency; color circularity; spectral images; unique colors; four-color map problem; perception

Online: 23 August 2016 (10:34:13 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints201607.0078.v2

Analysis between Various Random MIMO Systems Model on the Basis of Channel Capacity

Shree Krishna Acharya

Subject: Engineering, Electrical And Electronic Engineering Keywords: MIMO system Model; 2N–MIMO system model; Outage Probability; Channel Capacity Ratio (CCR)

Online: 10 August 2016 (10:11:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1990.v1

Enhancing Finger Fracture Diagnosis: A Deep Learning Approach Using ResNet and VGG

Shinawar Naeem, Asma Naseer, Shafiq ur Rehman, Volker Gruhn, Sheeraz Akram

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Classification; Transfer Learning; Deep learning; Finger Fracture; X-Rays

Online: 30 November 2023 (14:10:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0542.v1

Development of an HPLC Method through the QbD Approach for the Quantification of Honokiol and Metformin Hydrochloride – Method Validation and Pharmaceutical Applications on Oral Dosage Forms

Mousa Sha’at, Adrian Florin Spac, Iulian Stoleriu, Alexandra Bujor, Monica Stamate Cretan, Mihaela Hartan, Lăcrămioara Ochiuz

Subject: Medicine And Pharmacology, Pharmacy Keywords: QbD optimization; HPLC; validation; greenness; assay; dissolution test; metformin hydrochloride; honokiol; oral dosage forms; diabetes mellitus.

Online: 9 July 2024 (06:08:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1217.v1

Tightness of Harary Graphs

Abolfazl Javan, Ali Moeini, Mohammad Shekaramiz

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Network Vulnerability; Tightness; Harary Graphs; Connectivity; Hamiltonian Circuit

Online: 16 August 2024 (08:37:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0049.v1

A New Input Device for Spastics Based on Strain Gauge

Niels Buchhold, Christian Baumgartner

Subject: Engineering, Control And Systems Engineering Keywords: tactile sensors; assistive technologies; power wheelchair; medical systems; robotic; joystick; strain-gauge; spasticity

Online: 14 February 2017 (09:02:48 CET)

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Preprint REVIEW | doi:10.20944/preprints202405.1318.v1

Methodological Approaches and Literature Analysis in the Study of Soil Carbon in Urban Green Spaces: A Systematic Review

Francisco Tomatis, Dileyni Diaz De Oleo, Adriana Correa-Guimaraes, Salvador Hernández-Navarro, Luis Manuel Navas-Gracia

Subject: Engineering, Bioengineering Keywords: soil; carbon; cities; urban green spaces; mitigation; climate change

Online: 21 May 2024 (07:21:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0128.v1

Screening for Triterpenoid Saponins in Plants Using Hyphenated Analytical Platforms

Bekzod Khakimov, Li Hong Tseng, Markus Godeljohann, Søren Bak, Søren Balling Engelsen

Subject: Biology And Life Sciences, Plant Sciences Keywords: time slice LC-SPE-NMR/MS; GC-MS; LC-MS/MS; triterpenoid saponins; Barbarea vulgaris

Online: 25 November 2016 (10:04:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0396.v1

Bi-directional Full-Color Generation and Tri-channel Information Encoding Based on a Plasmonic Metasurface

Dewang Huo, Guoqiang Li

Subject: Physical Sciences, Optics And Photonics Keywords: plasmonic metasurface; full-color generation; tri-channel information encoding; polarization encoding

Online: 5 April 2024 (15:57:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0980.v1

Impact of Utilizing Visual Stimuli (BlazePod) on Agility, Vertical jump, and Visual Reaction Time Speed in Under-19 Volleyball Players

Youssef Zekailiche, Houda Bougrine, Jihen Khalfoun, Nidhal Jebabli, Rachad Djeddi, Foued Saad Saoud, Abderraouf Ben Abderrahman

Subject: Public Health And Healthcare, Other Keywords: Blazepod technology; Agility; Speed visual reaction time; Vertical Jump; Volleyball Physical skills

Online: 18 March 2024 (09:51:36 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202408.0349.v1

Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers

Ünal Metin Tokat, Ashkan Adibi, Esranur Aydın, Eylül Özgü, Şevval Nur Bilgiç, Onur Tutar, Merve Özbek Doğançay, İrem Demiray, Mutlu Demiray

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Personalized immunotherapy; Precision oncology; Immune checkpoint inhibitor (ICI); Integrative therapies; Adenoid cystic carcinoma (ACC); Frameshift mutation; Splice site mutation

Online: 6 August 2024 (12:39:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0148.v1

Systemic Analysis of Certified Artisan Cheese Production for Improvement—The Case of the Serra da Estrela PDO Cheese

Denis A. Coelho, Tiago E. P. Carrola, Ana F. Couvinhas

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: process improvement; ewe’s cheese; systemic design

Online: 30 December 2016 (07:34:54 CET)

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The research reported on this paper was aimed at improving the overall efficiency of a PDO certified artisanal cheese production process. Being a PDO certified foodstuff by the EU, it is considered to have properties and qualities determined by the geographical environment in which is made, with its production taking place in a specific and determined geographical location, in this case the Serra da Estrela region. In that sense, the authors conducted a mapping according to a systemic perspective of the processes involved in the context of manufacturing and distribution of certified Serra da Estrela cheese. Numerous methods were used throughout the process, such as a systemic design analysis, and techniques derived from ethnographic methods, which led to the collection of data in the field and consequently provided the immersion of the researcher in genuine work situations. Critical points were identified and emphasized in the systemic map with the purpose of encouraging initiatives to address and overcome the gaps and inefficiencies detected. The systemic design analysis triggered the development of design work. Observations following an ethnographic approach identified ergonomic risks in cheese making during the process of cutting excess chips, fostering the emergence of musculoskeletal disorders at the wrist. A tool that fits best to the task at hand was developed. A prototype of the new tool enabled collecting feedback from use in the work context, in order to inform product development. The domains of agricultural production and microbiology, considering the specific microorganisms developed trough the ripening process of the cheese, turned out to be aspects of high importance for the issue under focus, contributing to a broader understanding of the ripening process and its risks, simultaneously improving the efficiency and success of cheese production. If it were not for the systemic analysis, which served as a link between the boundaries of distinct domains such as the risk of microorganism contamination, ergonomics, energy efficiency, legislation and regulation policies, transportation challenges and economic viability, approached throughout the research. Simultaneously creating bridges between them, the various problems might not have been detected in the first place, as they are usually addressed in specialized disciplines, predetermined by the restrictions of each specific area of knowledge. As a consequence of the development of this research, which was based on an analysis that sought to establish possible connections between various disciplines and tried to constantly maintain a holistic perspective, making new connections and observing the issues from a new angle, apart from the already established methodologies. All this allowed to lay out the seeds for the development of a plan to tackle the critical points identified by the systemic analysis reported in this paper.

Preprint ARTICLE | doi:10.20944/preprints202408.1717.v1

Formulation and Characterization of DES and Potential Application in Recycling Packaging Laminates

Adamantini Loukodimou, Christopher Lovell, Tianmiao Li, George Theodosopoulos, Kranthi Kumar Maniam, Shiladitya Paul

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: DES; laminate packaging materials; blister packs; recycle; carboxylic acids; delamination

Online: 23 August 2024 (10:31:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.0973.v1

A Comprehensive Review on Viscoelastic Parameters Used for Engineering Materials Including Soft Materials and the Relationships between Different Damping Parameters

Hasan Koruk, Srinath Rajagopal

Subject: Engineering, Bioengineering Keywords: damping; complex modulus; loss factor; characterization; soft material; ultrasound; viscoelastic properties; viscosity; dynamic indentation; rheometry

Online: 14 August 2024 (09:29:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0018.v1

Soil Tillage Systems and Wheat Yield in Climate Change Scenarios

Pieranna Servadio, Simone Bergonzoli, Claudio Beni

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: soil tillage; tractors; soil water content; physical soil properties; GPS; energy requirement; CO2 emission

Online: 2 August 2016 (12:50:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1101.v1

Interface Design For Autism In An Ever-Updating World

Lewis D. Sawyer, Ramaswamy Palaniappan

Subject: Computer Science And Mathematics, Computer Science Keywords: Accessibility; ASD; Autism; Change Impact; HCI; Human Factors; Software Updates

Online: 17 June 2024 (08:33:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1056.v1

Circulating miR-16 and miR-21 Levels in Multiple Myeloma: Prognostic Significance of Survival and Response to Lenalidomide Treatment.

Annita Ioanna Gkioka, Maria Tsota, Aspasia Koudouna, Alexandros Gkiokas, Christina Aggeliki Mitropoulou, Aikaterini Palaiokrassa, Alexandros Alexandropoulos, Mavra Papadatou-Gigante, Vasiliki Bartzi, Thomais Marina Tryfou, Petros P Sfikakis, George V. Dedoussis, Marie Christine Kyrtsonis

Subject: Biology And Life Sciences, Life Sciences Keywords: Multiple myeloma, miR-16, miR-21, prognosis, lenalidomide, serum expression level, downregulation.

Online: 16 April 2024 (12:01:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0657.v1

Impact of Alcalase Hydrolysis and Simulated Gastrointestinal Digestion on the Release of Bioactive Peptides From Erythrina edulis (Chachafruto) Proteins

Jessica L. Correa, Jose Edgar Zapata, Blanca Hernández-Ledesma

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Erythrina edulis; enzymatic hydrolysis; in vitro gastrointestinal digestion; peptides; antioxidant; macrophages.

Online: 9 July 2024 (14:03:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1610.v1

Inheritance of Mitochondria in Pelargonium Section Ciconium (Sweet) Interspecific Crosses

Floris C. Breman, Joost Korver, Ronald Snijder, Eric Schranz, Freek T. Bakker

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Pelargonium; mitochondrion; inheritance; CNI; Ciconium

Online: 24 April 2024 (11:31:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0628.v1

Investigation of Inter- and Intra-Chain Interactions in Mixtures of Long-Chain Polymer Monomer with Relations to Applications in agriculture of Plant Cuticular Waxes: Using n-Nonadecane and 1-Octadecanol Mixture as example

Wentao Guo, Yi Xing, Wei Wen, Wei Su, Changjiang Hou, Guotao Li, Lyumeng Ye

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: Organics; Crystallization; Binary system; Phase transition; Thermodynamics; Long-Chain Polymer Monomer.

Online: 11 March 2024 (12:53:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202405.2103.v1

Bifidobacterium infantis and Bifidobacterium breve Improve Symptomatology and Neuronal Damage in Neurodegenerative Disease. A Systematic Review.

Manuel Reiriz, Ana Isabel Beltrán-Velasco, Víctor Echeverry-Alzate, Esther Martínez-Miguel, Silvia Gómez-Senent, Sara Uceda, Vicente Javier Clemente-Suárez

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: neurodegenerative disease; probiotics; Alzheimer´; s disease; Parkinson´; s disease; neurodegenerative process; Bifidobacterium infantis; Bifidobacterium longum subsp. infantis; Bifidobacterium breve

Online: 31 May 2024 (08:10:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1918.v1

A Novel Image Compression Method Based on Coordinated Group Signal Transformation

Ekaterina Lopukhova, Grigory Voronkov, Igor Kuznetsov, Vladislav Ivanov, Ruslan Kutluyarov, Elizaveta Grakhova

Subject: Engineering, Telecommunications Keywords: energy-efficient coding; differential coding; coordinated group signal transformation; image compression; image quality criteria; neural networks

Online: 30 April 2024 (11:30:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0333.v1

The Relationship between Job Strain and Ischemic Heart Disease, Mediated by Endothelial Dysfunction Markers and Imaging

PALOMA MOISII, IRINA JARI, ANDRA MARA URSU, ALEXANDRU GRATIAN NAUM

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: coronary artery disease; cardiovascular risk; job strain; high sensitivity C reactive protein; microalbuminuria

Online: 4 April 2024 (09:16:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1983.v1

Polycyclic Aromatic Hydrocarbons (PAHs) in Freshwater Systems: A Comprehensive Review of Sources, Distribution, and Impacts

Pedro J. Berríos-Rolón, María Cotto, Francisco Márquez

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Polycyclic Aromatic Hydrocarbons; Water Pollution; Ecotoxicology; Environmental Distribution; Analytical Methods; Regulatory Frameworks.

Online: 30 April 2024 (11:22:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0229.v1

Numerical Coupling between a FEM Code and the FVM Code OpenFOAM by Using the MED Library

Sandro Manservisi, Giacomo Barbi, Antonio Cervone, Federico Giangolini, Lucia Sirotti

Subject: Engineering, Energy And Fuel Technology Keywords: CFD; Code coupling; Conjugate Heat Trasfer

Online: 3 April 2024 (08:09:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2127.v1

Research on Visual/Ins Integrated Navigation Technology Based on FGO

Xun Cheng, Yu Wang

Subject: Engineering, Control And Systems Engineering Keywords: Visual/INS integrated navigation; Image de-blurring; Factor graph optimization (FGO); Nonlinear optimization; Multi-sensor fusion

Online: 31 May 2024 (10:50:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1035.v1

The Hydroxyapatite-Filled Acrylonitrile-Butadiene Rubber Composites with Improved Cure Characteristics and Reduced Flammability

Magdalena Maciejewska, Przemysław Rybiński, Anna Sowińska-Baranowska

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: acrylonitrile-butadiene rubber; hydroxyapatite; filler; flammability; silane; ionic liquid; surfactant; vulcanization; dispersibility

Online: 12 July 2024 (12:08:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1334.v1

New Spectrophotometric Visible (VIS) Analysis to determine Sodium Valproate from Tablets

CRISTIAN-CATALIN GAVAT

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Sodium valproate; antiepileptic drug; spectrophotometric quantitative analysis method; light yellow azo dye; official declared pure amount; quantitative color reaction; statistical validation procedure

Online: 19 August 2024 (14:27:53 CEST)

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Preprint REVIEW | doi:10.20944/preprints202409.0310.v1

Evaluating Mobility in Parkinson’s Disease through Wearable Sensors: A Systematic Review of Digital Biomarkers

Carlos Polvorinos-Fernández, Luis Sigcha, Luigi Borzì, Gabriella Olmo, César Asensio, Juan Manuel López, Guillermo de Arcas, Ignacio Pavón

Subject: Engineering, Bioengineering Keywords: Parkinson’ s disease; digital biomarkers; motor symptoms; ; wearables; body-worn sensors; machine learning

Online: 4 September 2024 (08:32:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.2142.v1

What Quality Suffices in Nanopore Metabarcoding? Reconsidering Methodology and Ectomycorrhizae in Decaying Fagus sylvatica Bark as a Case-Study

Glen Dierickx, Lowie Tondeleir, Pieter Asselman, Kris Vandekerkhove, Annemieke Verbeken

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Nanopore; deadwood; ectomycorrhiza; Fagus sylvatica; quality filtering; Phred score; eNano pipeline; natural regeneration; metabarcoding

Online: 29 August 2024 (10:40:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1075.v1

Proposition of an Innovative Methodology Coupling Structure from Motion Photogrammetry and Reflectance Transformation Imaging as a Standard Workflow Tool for Documenting and Researching Painted Surfaces in 2.5D. The Case Study of a Mural Painting from the Palace of Tiryns

Georgios Tsairis, Athina Alexopoulou, Nicolaos Zacharias, Ioanna Kakoulli

Subject: Arts And Humanities, Archaeology Keywords: 2.5D imaging; (SfM) structure from motion Photogrammetry; (MVS) multi-view stereo; (RTI) reflectance transformation imaging; heritage documentation; painting conservation

Online: 14 August 2024 (16:38:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0374.v1

Patients’ Satisfaction regarding Oral Healthcare Services in the North-East Region of Romania: A Questionnaire Survey

Silviu Catalin Tibeica, Dragoș Ioan Virvescu, Iulian Costin Lupu, Dana Gabriela Budala, Ionut Luchian, Andreea Tibeica, Zinovia Surlari, Elena Mihaela Carausu

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: oral health; dental management; quality of life; patient satisfaction; quality management; dental services

Online: 4 April 2024 (12:14:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0077.v1

Enhancing Sustainable Construction: Optimization Tool for Glulam Roof Structures according to Eurocode 5

María Simón-Portela, José Ramón Villar-García, Pablo Vidal-López, Desirée Rodríguez-Robles

Subject: Engineering, Architecture, Building And Construction Keywords: artificial intelligence; genetic algorithm; timber; roof structure; Eurocode 5

Online: 1 April 2024 (17:18:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2590.v1

Assessing the Reliability of the Sexual Violence Questionnaire in Sport Among Spanish-Speaking Athletes

Andrea Sáenz-Olmedo, Aitor Iturricastillo, Jon Brain, Luis Maria Zulaika, Oidui Usabiaga

Subject: Social Sciences, Gender And Sexuality Studies Keywords: Sexual violence; experiences; perceptions; coach-athlete relationship; sport

Online: 1 August 2024 (05:39:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2010.v1

Research on Underwater SLAM System Based on Visual Feature Enhancement

Haiyang Qiu, Yijie Tang, Hui Wang, Lei Wang, Dan Xiang, Mingming Xiao

Subject: Computer Science And Mathematics, Robotics Keywords: underwater SLAM; underwater image processing; visual feature point enhancement; association of acoustic and visual feature

Online: 30 May 2024 (11:03:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0128.v1

Elacestrant Plus Alpelisib in an ESR1 and PIK3CA Co-mutated and Heavily Pretreated Metastatic Breast Cancer: The First Case for Combination Efficacy and Safety

Ünal Metin Tokat, Şevval Nur Bilgiç, Esranur Aydın, Ashkan Adibi, Eylül Özgü, Onur Tutar, Mutlu Demiray

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: HR+/HER2- metastatic breast cancer; HR-positive; Selective estrogen receptor degrader (SERD); Elacestrant; Alpelisib; Precision oncology; Cancer genomics

Online: 2 August 2024 (03:52:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.1683.v1

Biological Carbon Sequestration: From Deep History to the Present Day

Denis J. Murphy

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Anthropocene; carbon sequestration; carboniferous; climate change; agriculture; CO₂; holocene; photosynthesis

Online: 27 May 2024 (07:42:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0373.v1

Characterization of a Multilayer Film Comprising Polybutylene Adipate Terephthalate and Cellulose Nanocrystals with High Barrier and Compostable Properties

Beatriz Melendez-Rodriguez, Cristina Prieto, Maria Pardo-Figuerez, Inmaculada Angulo, Ana I. Bourbon, Isabel R. Amado, Miguel A. Cerqueira, Lorenzo M. Pastrana, Loic Hugues Gilles Hilliou, António A. Vicente, Luis Cabedo, Jose M. Lagaron

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: biopolyesters; nanocellulose; multilayers; compostable; packaging

Online: 7 May 2024 (10:48:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0032.v1

Exploiting Symmetric Energy Harvesting Protocol in Wireless Sensor Networks with Outdated Channel State Information: Protocol Design and Performance Analysis

Dinh-Thuan Do, Hoang-Sy Nguyen, Miroslav Voznak

Subject: Engineering, Electrical And Electronic Engineering Keywords: channel state information; energy harvesting; amplify-and-forward; time power switching relaying; throughput

Online: 8 September 2016 (11:59:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0078.v1

Gender Differences in Performing an Overhead Drilling Task Using an Exoskeleton- a Cross-Sectional Study

Bettina Wollesen, Julia Katharina Graef, Sander De Bock, Eligia Alfio, Maria Alejandra Diaz, Kevin De Pauw

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: supportive systems; gender comparison; over-shoulder working task

Online: 3 September 2024 (05:28:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0050.v1

Frictional Behavior of Chestnut (Castanea sativa Mill.) Sawn Timber for Carpentry and Mechanical Joints in Service Class 2

José Ramón Villar-García, Manuel Moya-Ignacio, Pablo Vidal-López, Desirée Rodríguez-Robles

Subject: Engineering, Architecture, Building And Construction Keywords: friction coefficient; tribology; mechanical properties; contact simulation; Eurocode 5

Online: 1 April 2024 (13:24:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1297.v1

Fabrication and Characterisation of Sustainable 3D Printed Parts Using Post-consumer PLA Plastic and Virgin PLA Blends

Mohammad Raquibul Hasan, Ian J Davies, Alokesh Paramanik, Michele John, Wahidul Biswas

Subject: Engineering, Mechanical Engineering Keywords: Additive manufacturing; post-consumer PLA (PC-PLA) waste; blended filament; mechanical properties; circular economy

Online: 22 March 2024 (08:12:34 CET)

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Sustainable manufacturing practices are becoming increasingly necessary due to the growing concerns regarding climate change and resource scarcity. Consequently, material recycling technologies have gradually become preferred over conventional processes. This study aimed to recycle waste polylactic acid (PLA) from household-disposed cups and lids to create 3D-printed parts and promote sustainable manufacturing practices. To achieve this, the current study utilised virgin and post-consumer PLA (sourced from household waste) blends. The PC-PLA wastes were shredded and sorted by size with the aid of a washing step, resulting in a filament with a 1.70 ± 0.5 mm diameter without fragmentation or dissolution. A 50:50 wt.% blend of virgin PLA (vPLA) and PC-PLA was selected as the standard recycling percentage based on previous research and resource conservation goals. The study investigated the impact of three 3D printing parameters (layer height (LH), infill density (I), and nozzle temperature (NT))on the quality of 3D-printed parts using a three-level L9 Taguchi orthogonal array. The findings revealed that blending PC-PLA with vPLA led to significant improvements in the tensile, flexural, and impact strengths by 18.40%, 8%, and 9.15%, respectively, compared to those of recycled PLA. This conclusion was supported by the investigation of the fracture surface area, which revealed fractographic features associated with printing parameters, such as plastic deformation and interfilament debonding. An ANOVA analysis revealed a positive influence of larger layer height and high nozzle temperature on the mechanical properties. Subsequently, the optimal printing parameters (LH: 0.3 mm, I: 100%, and NT: 215 °C) were determined using the S/N ratio, and a confirmation test using the optimum printing parameters exhibited a strong correlation with statistically predicted outcomes. Finally, the study used optimum printing parameters to fabricate 100% post-consumer recycled PLA 3D printed parts, demonstrating their potential for low-strength applications. Based on these findings, it can be concluded that virgin and post-consumer recycled PLA blended filament for fabricating 3D printed components is an effective way to support plastic recycling in the context of a circular economy.

Preprint ARTICLE | doi:10.20944/preprints202406.0744.v1

Influence of Glycerol on the Surface Morphology and Crystallinity of Polyvinyl Alcohol Films

Ganna Kovtun, David Casas, Teresa Cuberes

Subject: Chemistry And Materials Science, Nanotechnology Keywords: polyvinyl alcohol films pva/glycerol blends; crystallinity; infrared spectroscopy; x-ray diffraction; thermogravimetry; differential thermal analysis; atomic force microscopy; lateral force microscopy; ultrasonic force microscopy

Online: 12 June 2024 (14:07:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0871.v1

Simulation-Guided Analysis Towards Trench Depth Optimization for Enhanced Flexibility in Stretch-Free, Shape-Induced Interconnects for Flexible Electronics

Daniel Joch, Thomas Lang, Shawn Sanctis, Michael Jank

Subject: Engineering, Electrical And Electronic Engineering Keywords: stretchable electronics; mechanical design; structural design; numerical simulation; fabrication strategy; island-bridge

Online: 10 July 2024 (14:06:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.0532.v1

Application of additive manufacturing in automobile industry: a mini review

Jian Yang, Bo Li, Jian Liu, Zhantong Tu, Xin Wu

Subject: Engineering, Automotive Engineering Keywords: additive manufacturing; automobile industry; printable materials; product quality

Online: 9 May 2024 (12:09:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1365.v1

Rifampicin Loaded PLGA/Alginate Grafted pNVCL-Based Nanoparticles for Wound Healing

Tudor Bibire, Daniel Vasile Timofte, Radu Dănilă, Alina Diana Panainte, Cătălina Natalia Yilmaz, Nela Bibire, Luminita Agoroaei, Cristina Mihaela Ghiciuc

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: alginate; NVCL; nanoparticle; rifampicin; IC50; wound healing

Online: 19 September 2024 (08:43:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0497.v1

Effectiveness of a Polyphenolic-Enriched Blend on Weight Management and Metabolic Syndrome-Related Parameters in Healthy, Overweight Adults

Alejandro Martínez-Rodríguez, Maria Martínez-Olcina, Manuel Vicente-Martínez, Nuria Asencio-Mas, Pau Navarro, Nuria Caturla, Jonathan Jones

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Hibiscus sabdariffa; Lippia citriodora; weight management; satiety; body fat; cholesterol

Online: 8 April 2024 (07:03:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0332.v1

Differential protective effect of zinc and magnesium for the hepatic and renal toxicity induced by acetaminophen and potentiated with ciprofloxacin in rats

Alexandra Moraru (Ciocan), Diana C. Ciubotariu, Cristina Mihaela Ghiciuc, Catalina Elena Lupusoru, Mihnea Eudoxiu Hurmuzache, Radu Crișan-Dabija

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: magnesium chloride (MgCl2); zinc gluconate (ZnG); liver diseases; kidney diseases

Online: 6 March 2024 (13:55:48 CET)

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Background: The purpuse was to investigate the influence induced by magnesium chloride (MgCl2) and zinc gluconate (ZnG) supplementation on liver and kidney injuries experimentally-induced with acetaminophen (AAPh) and potentiated by ciprofloxacin addition in rats. Material and methods: The experiment was performed on 5 animals groups: group 1 – control, treated for 6 weeks with normal saline, 1mL/kg; group 2 – AAPh, treated for 6 weeks with AAPh, 100 mg/ kg/day; group 3 – AAPh+C, treated AAPh 100 mg/kg/ day for 6 weeks and ciprofloxacin, 50mg /kg/day, only in the last 14 days of the experiment; group 4 – AAPh+C+Mg, with the same treatment as group 3, but, and in the last 14 days, MgCl2 10 mg/ kg/day was added; group 5 – AAPh+C+Zn, with the same treatment as group 3, but, and in the last 14 days, zinc gluconate (ZnG),10 mg/kg/day was added. All administrations were performed by oral gavage. At the end of the experiment, the animals were sacrificed and blood samples were collected for biochemistry examinations. Results: Treatment with AAPh for 6 weeks determined an alteration of the liver function (increases in alanine aminotransferase, aspartate aminotransferase, lactic dehydrogenase and, and gamma-glutamyl transferase) and of renal function (increases in serum urea and creatinine) (P < 0.001 group 2 vs. group 1 for all mentioned parameters). Also, the antioxidant defense capacity was impaired in group 2 vs. group 1 (superoxide dismutase and glutathione peroxidase activity decreased in group 2 vs. group 1, 0.001 < P < 0.01, respectively 0.01 < P < 0.05). The addition of ciprofloxacin, 50 mg/kg/day during the last 14 days resulted in further increases in alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, urea and creatinine (0.01 < P < 0.05, group 3 vs. group 2). MgCl2 provided a slight protection against liver enzymes increase and a more pronounced protection against the increase in serum urea and creatinine (0.001 < P < 0.01 group 4 vs. group 3). MgCl2 provided a slight protection against the decrease in superoxide dismutase (0.01 < P < 0.05 group 4 vs. group 3), but not against decrease of glutathione peroxidase. The improvement of mentioned parameters could also be seen in case of ZnG, to a higher extent especially in the case of alanine aminotransferase and lactic dehydrogenase (0.01 < P < 0.05 group 5 vs. group 4). Conclusions: This study represents a furthermore proof for beneficial effect of magnesium and zinc salts against toxicity induced by different agents, including antibacterials added to the analgesic and antipyretic acetaminophen; the protection is proven on the liver and kidney’s function; the antioxidant profile improvement has a key role, especially in case of zinc gluconate.

Preprint ARTICLE | doi:10.20944/preprints202403.0696.v1

Epidemiological Study on a Wilson Disease Group of Patients

Liviu Moraru, Mihaela-Alexandra Budianu, Isabela-Raluca Musteață, Toader Septimiu Voidazan

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Wilson disease; Romania; symptoms; Kayser-Fleischer ring

Online: 12 March 2024 (07:57:10 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.1335.v1

Article Review: Role and Functionality of Ingredients in Plant-Based Meat Analogue Burgers

Gil Vila-Clarà, Anna Vila-Martí, Laia Vergés-Canet, Miriam Torres-Moreno

Subject: Biology And Life Sciences, Food Science And Technology Keywords: meat analogues; plant-based meat; plant-based burgers; functionality; food technology innovation; clean-label ingredients; composition; sustainability

Online: 22 March 2024 (11:00:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1540.v1

Simple Histogram Equalization Technique Improves Performance of VGG models on Facial Emotion Recognition Datasets

Jaher Hassan Chowdhury, Qian Liu, Sheela Ramanna

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Facial emotion recognition; Convolutional Neural Network; Histogram Equalization; Transfer Learning; VGG architecture

Online: 23 April 2024 (14:50:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1867.v1

Generalized weighted group inverse in Banach algebras with proper involution

Huanyin Chen

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: weighted generalized Drazin inverse; weighted group inverse; weak group inverse; complex matrix; Banach algebra.

Online: 27 June 2024 (08:10:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0029.v2

Distal [FeS]-Cluster Coordination in [NiFe]-Hydrogenase Facilitates Intermolecular Electron Transfer

Alexander Petrenko, Matthias Stein

Subject: Chemistry And Materials Science, Theoretical Chemistry Keywords: electron transfer; Marcus equation; enzymatic fuel cell; hydrogen oxidation; electrode adsorption; DFT; bioelectrochemistry

Online: 9 January 2017 (02:49:00 CET)

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Preprint REVIEW | doi:10.20944/preprints202406.0051.v1

Environmental Aspects and Recycling of Solid-State Batteries: A Comprehensive Review

Abniel Machín, María Cotto, Francisco Díaz, José Ducongé, Carmen Morant, Francisco Márquez

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Solid-state batteries; Sustainability; Recycling; Waste management; Green technology

Online: 4 June 2024 (02:53:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2007.v1

Computing Interface Curvature from Height Functions using Machine Learning with a Symmetry-preserving Approach for Two-phase Simulations

Antonio Cervone, Sandro Manservisi, Ruben Scardovelli, Lucia Sirotti

Subject: Engineering, Energy And Fuel Technology Keywords: curvature computation; volume of fluid; height function; machine learning; neural network

Online: 30 May 2024 (10:58:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1874.v1

A Comprehensive Review of MI-HFE and IPHFE Cryptosystems: Advances in Internal Perturbations for Post-Quantum Security

Yong Wang, Lingyue Li, Ying Zhou, Huili Zhang

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: RSA encryption; quantum-resistant cryptography; lattice-based cryptography; multivariate public key cryptosystems; NP-hard problems; quantum computing threats; digital security

Online: 24 September 2024 (10:06:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1137.v1

The Impact of Candida albicans in the Development, Kinetics, Structure, and Cell Viability of Biofilms on Implant Surfaces. An In Vitro Study with a Validated Multispecies Biofilm Model

Enrique Bravo, Marion Arce, Honorato Ribeiro-Vidal, David Herrera, Mariano Sanz

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: peri-implantitis; oral biofilm; Candida albicans; scanning electron microscopy; confocal laser scanning microscopy; quantitative polymerase chain reaction

Online: 20 February 2024 (14:39:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.1519.v1

Control Group in Foot Plantar Pressure Studies – Does Chronic Low Back Pain Matter?

Barbara Jasiewicz, Ewa Klimiec, Piotr Guzdek, Grzegorz Kołaszczyński, Krzysztof Zaraska, Slawomir Duda, Jacek Lorkowski, Tomasz Potaczek

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: foot; gait; low back pain

Online: 19 July 2024 (07:53:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0502.v1

Vector Optical Bullets in Dielectric Media: Polarization Structures and Group Velocity Effects

Sergej Orlov, Klemensas Laurinavičius, Ada Gajauskaitė

Subject: Physical Sciences, Optics And Photonics Keywords: Optical bullets; Focus wave modes; Polarization; Diffraction; Dispersion; Nondiffracting beams; Nondispersing pulses

Online: 8 April 2024 (05:16:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0638.v1

Immobilization of Cell Walls with Laccase in L-DOPA-Alginate Beads and Investigation of the Influence of Photopolymeriza-Tion on the Temperature Stability of Immobilized Cells and Their Ability for Textile Dye Decolorization

Nikolina Popović Kokar, Anamarija Nikoletić, Marija Stanišić, Milica Crnoglavac Popović, Radivoje Prodanović

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: algae biomass; alginate; yeast cells; laccase; surface display; hydrogel; photopolymerisation; bioremediation

Online: 9 April 2024 (13:08:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0110.v2

TPGS-Stabilized Curcumin Nanoparticles Exhibit Superior Effect on Carrageenan-Induced Inflammation in Wistar Rat

Heni Rachmawati, Dewi Safitri, Aditya Trias Pradana, I Ketut Adnyana

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: curcumin; nanoparticle; inflammation; λ-carrageenan; nanoparticle permeability; Biopharmaceutical Class System (BCS) 4

Online: 11 August 2016 (11:24:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0227.v1

Circadian Tuning with Metameric White Light: Visual and non-visual Aspects

Tamara Aderneuer, Oliver Stefani, Oscar Fernández, Christian Cajochen, Rolando Ferrini

Subject: Physical Sciences, Optics And Photonics Keywords: non-visual effect; metamerism; light-emitting diodes (LEDs); lighting; spectral optimization

Online: 19 September 2019 (15:43:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0584.v1

“Prevalence of Dental Caries and Dietary Determinants among 12–16 Years Old Students, a Cross-Sectional Study”

Suela Hoxha, Fatime Hoxha, Jaser Veseli, Xheneta Hoxha

Subject: Public Health And Healthcare, Other Keywords: DMFT; soft drinks; frequency; adolescents

Online: 9 May 2024 (10:34:04 CEST)

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Introduction: Caries is a public health problem in Kosovo among children, Caries is a multifactorial microbial disease and connection of this disease with soft drinks and food habits between children and their poor oral health is very strong. Aim: The aim of present study is to evaluate prevalence of caries among 12 to 16 years old students in municipality of Suhareka and to analyze related risk factors that contribute in occurrence of caries. Material and methods: To observe parameters of soft drink we used experimental method and a cross-sectional study was carried out among 120 adolescents in “Sadri Duhla” elementary school in Duhel and “7 Marsi” elementary school in city of Suhareka. Oral clinical examination and self administered questionnaire were used to collect information about dental caries and its correlation to soft drinks and food habits. Examination was done between May and October in the year 2023. Impact of soft drink in caries was assessed through DMFT index and frequency of consumption of soft drinks. The data were collected statistically using SPSS version 26 and presented in tables and graphs. Results: The highest result of DMFT (4.36) with standard deviation 1.23 was noted in the group consuming more than 16 cans per week also the highest score in adolescent compared to frequency of consumed cans per week. Soft drinks found in Kosovo’s mar-kets are acidic with low pH, 93.75% of them had a pH below 4 which are considered erosive and only 6.25% are minimally erosive with a pH > 4, in terms of buffer capacity soft drinks can be ordered like this energy drinks >soda >100% fruit juice > fruit drinks. Improper tooth-brushing, dental visits only in case of pain and not preventive visits were significantly related to dental caries. Conclusion: The results of the research awarned us for high frequency consumption of soft drinks related to dental caries. It is recommended to be aware of the use of soft drinks, regular visits to the doctor, higher maintenance of oral health by using paste with sufficient fluoride content also brushing teeth 1 hour after consuming acidic food.

Preprint COMMUNICATION | doi:10.20944/preprints202106.0636.v1

Geometrical Transformations and Development of Geometry

Joaquin Giménez, Xhevdet Thaqi, Yuly Vanegas

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: geometry; geometrical transformations; symmetry; invariance, perspectivity, Möbius transformations.

Online: 28 June 2021 (10:23:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0300.v1

Toward Intraoperative Visual Intelligence: Real-Time Surgical Instrument Segmentation for Enhanced Surgical Monitoring

Mostafa Daneshgar Rahbar, George Pappas, Nabih Jaber

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Intraoperative surgery; monitoring surgical scene; convolutional neural network; U-Net; data augmentation; surgical tools segmentation; computer vision; image processing

Online: 7 May 2024 (02:32:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1372.v1

Acute Stimulation of PBMCs Drives Switch from Dopamine-Induced Anti- to proinflammatory Phenotype of Monocytes Only in Women

Leonie Fleige, Silvia Capellino

Subject: Biology And Life Sciences, Other Keywords: dopamine; sex-specific differences; monocytes; B cells; cytokines; human

Online: 20 August 2024 (03:22:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1008.v1

Comparison of Optogalvanic and Laser-Induced Fluorescence Spectroscopy

Laurentius Windholz

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: Lanthanide spectroscopy; Optogalvanic detection; Laser-induced fluorescence detection

Online: 19 February 2024 (07:46:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0051.v1

Search for QPOs in the Light Curve of the Blazar OJ287: Preliminary Results from 2015/16 Observing Campaign

S. Zola, M. Valtonen, G. Bhatta, A. Goyal, B. Debski, A. Baran, J. Krzesinski, M. Siwak, S. Ciprini, A. Gopakumar, H. Jermak, K. Nilsson, D. Reichart, K. Matsumoto, K. Sadakane, K. Gazeas, M. Kidger, V. Piirola, F. Alicavus, K.S. Baliyan, A. Berdyugin, D. Boyd, M. Campas Torrent, F. Campos, J. Carrillo Gomez, D.B. Caton, V. Chavushyan, J. Dalessio, D. Dimitrov, M. Drozdz, A. Erdem, A. Escartin Perez, V. Fallah Ramazani, A.V. Filippenko, F. Garcia, F. Gomez Pinilla, M. Gopinathan, J.B. Haislip, J. Harmanen, G. Hurst, K.M. Ivarsen, M. Jelinek, A. Joshi, M. Kagitani, N. Kaur, N. Karaman, W.C. Keel, A.P. LaCluyze, B.C. Lee, E. Lindfors, J. Lozano De Haro, J.P. Moore, R. Naves Nogues, A.W. Neely, R.H. Nelson, W. Ogloza, S. Okano, J.C. Pandey, M. Perri, P. Pihajoki, G. Poyner, J. Provencal, T. Pursimo, A. Raj, R. Reinthal, S. Sadegi, T. Sakanoi, J.-L. Salto Gonzales, T. Schweyer, F.C. Soldan Alfaro, E. Sonbas, I. Steele, J.T. Stocke, J. Strobl, L.O. Takalo, T. Tomov, L. Tremosa Espasa, J.R. Valdes, J. Valero Perez, F. Verrecchia, J.R. Webb, M. Yoneda, M. Zejmo, W. Zheng, J. Telting, J. Saario, T. Reynolds, A. Kvammen, E. Gafton, R. Karjalainen, P. Blay

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: galaxies: active; BL Lacertae objects: individual (OJ 287); super massive black holes

Online: 18 July 2016 (10:46:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0878.v1

Gustatory-Visual Interaction in Human Brain Cortex: fNIRS Study

Karolina Jezierska, Aneta Cymbaluk-Płoska, Justyna Zaleska, Wojciech Podraza

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: fNIRS; taste stimulation; human brain cortex; gustatory-visual interaction

Online: 11 July 2024 (10:00:50 CEST)

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Background: many studies, on for example taste-visual dissonance, have shown that the influence of the visual cortex on taste sensation is enormous. The aim of the presented work is to investigate, using fNIRS, whether a taste stimulus, in this case the taste of bitter, also causes stimulation of the visual cortex in fNIR study. Methods: 51 participants (204 examinations, 9 996 records) were examined with fNIRS, which collects signals from whole left hemisphere. Differences between the maximum and minimum changes in oxyHb concentrations (ΔoxyHb) for the areas of the brain cortex considered responsible for recording visual and gustatory signals were analyzed. Protocol I, II, III and IV – activation with distillate water, coffee with lower concentration, reference (no stimulation) and coffee with higher concentration respectively, were used. Results: We recorded high signals for teste activation on channels covered gustatory cortex, which confirms the correctness of the choice of research method. What seems important, and somewhat surprising, is the fact that we also received high signals for the channels 45-49, which cover the visual cortex. The statistical analysis does not show any statistical differences between the protocols I, II and IV (different taste activation – water, coffee A and coffee B) for specific channels. As a results of the analysis of the correlation between the subjective bitterness assessment solutions, and the signal ΔoxyHb height, it was observed that statically important correlation, although weak, occurs only for 14 and gustatory channels, only for coffee with a higher concentration. Additionally we recorded the only statistically significant difference between women and men for protocol I (water), where the ΔoxyHb signal was twice as high for women. Conclusions: In conclusion, we can clearly state that the senses of sight and taste work closely together. Moreover, this cooperation is not one-sided - not only the visual activation affects the perception of taste, but interestingly, the taste stimulus can generate a hemodynamic response - activity in the visual cortex.

Preprint ARTICLE | doi:10.20944/preprints202402.0491.v1

LIVEnet: Linguistic-Interact-with-Visual Engager Domain Generalization for Cross-Scene Hyperspectral Imagery Classification

Yuanyuan Dang, Xianhe Zhang, Bing Liu

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Hyperspectral image (HSI) classification; Contrastive learning; CLIP; Domain generalization; Linguistic-Visual alignment

Online: 8 February 2024 (07:07:56 CET)

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Preprint CASE REPORT | doi:10.20944/preprints201701.0136.v1

Eco-Safety Assessment of Glyoxal-Containing Cellulose Ether on Freeze-Dried Microbial Strain, Cyanobacteria, Daphnia, and Zebrafish

Chang-Beom Park, Min Ju Song, Nak Woon Choi, Sunghoon Kim, Hyun Pyo Jeon, Sanghun Kim, Youngjun Kim

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Aquatic-toxic effects; EU chemical regulation; Glyoxal-containing cellulose ether

Online: 31 January 2017 (12:10:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0768.v1

Towards Cognition-Aligned Visual Language Models via Zero-Shot Instance Retrieval

Teng Ma, Daniel Organisciak, Wenbao Ma, Yang Long

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Large Visual Language Models; Zero-Shot Instance Retrieval; Cognition-Alignment

Online: 13 March 2024 (07:29:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1849.v1

Long-Term Organic Cultivation in Greenhouses Enhances Vegetable Yield and Soil Carbon Accumulation through the Promotion of Soil Aggregation

Lihong Tong, Yingjun Liu, Tian Lan, Xiayan Liu, Lechuan Zhang, Adu Ergu, Yajie Wen, Xiang Liu

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: organic cultivation; soil aggregates; organic carbon fraction; microbial community; enzyme activity

Online: 29 March 2024 (13:20:51 CET)

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The long-term use of fertilizers and pesticides in conventional cultivation has resulted in a decrease in soil productivity and vegetable yields in greenhouses. However, only a limited number of studies have explored the impacts of organic cultivation on greenhouse soil. Specifically, there is a scarcity of research examining the alterations in soil aggregate mediated organic carbon and microbial communities, which are known to enhance soil productivity. This study investigated the properties of soil aggregates, including the levels of organic carbon fractions, microbial community, and enzyme activity with the three aggregate classes microaggregates (<0.25 mm), small macroaggregates (2-0.25 mm) and large macroaggregates (>2 mm). These investigations were conducted under three different cultivation methods in a greenhouse: conventional cultivation (CC), integrated cultivation (IC), and organic cultivation (OC) in greenhouse. The results showed that (1) OC and IC promoted the formation of small macro-aggregates and enhanced aggregate stability compared to CC, (2) SOC in the three size fractions of OC increased by 98.99%-92.06% compared to CC; EOC increased by 98.47%-117.59%; POC increased by 138.59%-208.70%; MBC increased by 104.71%-230.61%; DOC increased by 21.93%-40.90%, respectively; (3) Organic cultivation significantly increased enzyme activity in all three particle size aggregates and increased the relative abundance of bacteria in micro-aggregates as well as the relative abundance of fungi in small macro-aggregates. Structural equation model (SEM) analysis revealed that organic farming practices fostered the development of smaller macro-aggregates, elevated microbial and enzyme activities within soil aggregates, and facilitated the conversion of soil nutrients and carbon sequestration. consequently, this led to an increase in soil organic carbon content and improved vegetable yield in greenhouse environments. In conclusion, the soil carbon content and vegetable yield are enhanced through long-term organic cultivation in greenhouses, primarily by increasing the proportion of small macro-aggregates.

Preprint ARTICLE | doi:10.20944/preprints202307.0034.v1

Simultaneous Quantification of 16 Bisphenol Analogues in Food Matrices

Fiorella Lucarini, Rocco Gasco, Davide Staedler

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: bisphenol analogues; canned foods; food matrices; QuEChERS; GC-MS; LC-MS/MS; endocrine disruptors

Online: 3 July 2023 (09:35:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1136.v1

Mismatch Responses to Speech Contrasts in Preschoolers With and Without DLD

Ana Campos, Jyrki Tuomainen, Outi Tuomainen

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: DLD; multifeature paradigm; mismatch response; ERPMMR time-frequency analysis

Online: 17 November 2023 (04:36:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0684.v1

Epidemiology and Sex-related differences in extracranial complications in ICU patients with traumatic brain injury.

Manuel Cruz-Garcinuño, Raúl Juárez-Vela, Antonio Martínez-Sabater, Elena Chover-Sierra, Juan Luis Sánchez-González, Vicente Gea-Caballero, Maria Luisa Ballestar-Tarín, Ainhoa Serrano Lázaro, Ana Cobos-Rincón, Kapil Laxman Nanwani Nanwani, Regina Ruiz de Viñaspre-Hernández, Manuel Quintana-Diaz

Subject: Public Health And Healthcare, Nursing Keywords: Critical Care; Epidemiology; Brain Injuries; Intensive Care; Craniocerebral Trauma; Data Interpretation

Online: 9 July 2024 (05:45:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0154.v1

MgAl Oxide Coatings Modified with CeO2 Particles Formed by Plasma Electrolytic Oxidation of AZ31 Magnesium Alloy: Photoluminescent and Photocatalytic Properties

Stevan Stojadinović, Nenad Radić

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: plasma electrolytic oxidation; photocatalysis; photoluminescence, MgO, MgAl2O4, methyl orange

Online: 6 March 2024 (04:01:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1382.v2

Acoustic Characterization of Potential Quiet Areas in Dortmund, Germany

Bryce T. Lawrence, Andreas Frücht, Damian Heying, Kai Schröer, Dietwald Gruehn

Subject: Social Sciences, Geography, Planning And Development Keywords: Noise Action Plan; Noise Mapping; Quiet Areas; Biophony Mapping; Diel Patterns; Noise Hot Spot; Multiple Decision Criteria Assessment; Linear Combination Suitability Mapping

Online: 11 March 2024 (13:17:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.2061.v1

Combining Translation Readthrough Inducing Drugs and Nonsense Mediated Decay Pathway Inhibition to Rescue of CFTRW1282X in Cystic Fibrosis Cell Model System

Roberta Bongiorno, Emanuele Vitale, Davide Ricci, Pietro Salvatore Carollo, Ivana Pibiri, Raffaella Melfi, Andrea Pace, Laura Lentini

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: premature termination codon; nonsense mutation; Nonsense-mediated decay; translational readthrough inducing drugs; oxadiazoles.

Online: 29 June 2024 (00:09:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1275.v1

Numerical Algorithms for Divergence-Free Velocity Applications

Giacomo Barbi, Antonio Cervone, Sandro Manservisi

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: divergence-free velocity; Raviart-Thomas finite elements; mass conservation

Online: 16 July 2024 (10:15:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0371.v1

Exploring the Diversity and Potential Use of Flower-Derived Lactic Acid Bacteria in Plant-Based Fermentation: Insights into Exo-Cellular Polysaccharide Production

Azadeh Khiabani, Hang Xiao, Anders Peter Wätjen, Miguel Tovar, Vera Kuzina Poulsen, Egon Bech Hansen, Claus Heiner Bang-Berthelsen

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Exo-cellular polysaccharide; Plant-based fermentation; Isolation; Flower; Lactic acid bacteria; Texture

Online: 6 August 2024 (06:20:57 CEST)

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