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NIH funds new research to combat emerging viruses

Albert Einstein College of Medicine has received a five-year, $14 million per year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to participate in a broad national effort to develop "plug-and-play" vaccines and antibody-based therapies against a wide range of emerging viruses. The grant is part of NIAID's new Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network, which was announced earlier today.

14 Sep 2024

AI-powered treatment allocation improves public health outcomes

A new study sheds light on a promising approach using machine learning to more effectively allocate medical treatments during a pandemic or any time there's a shortage of therapeutics.

14 Sep 2024

Scientists develop novel technique to combat T cell exhaustion

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion. This phenomenon also hinders adoptive cell therapies, in which healthy, tumor-targeting T cells are infused into patients with cancer. A novel method to boost mitochondrial activity and charge up T cells is needed.

14 Sep 2024

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Mount Sinai researchers have identified a key driver of a blood vessel disorder known as fibromuscular dysplasia (FMD) which affects up to five percent of the adult population and can lead to high blood pressure, heart attack, or stroke.

14 Sep 2024

Real-world data reveals factors associated with long-term weight loss in obesity

A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity. The study was published in JAMA Network Open.

14 Sep 2024

New drug shows strong activity against brain metastases in HER2-positive breast cancer

A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer.

13 Sep 2024

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy.

13 Sep 2024

National survey reveals vaccine hesitancy ahead of flu and COVID-19 season

With flu season just around the corner and COVID-19 cases on the rise, a new nationwide survey from The Ohio State University Wexner Medical Center reveals hesitancy around vaccines this fall.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

Significant global cardiovascular risk linked to high lipoprotein(a) levels

Review in The Lancet finds that one in five globally are at risk of contracting cardiovascular diseases, because they carry a genetic risk of high levels of a specific lipoprotein, which can be tested for and possibly treated.

12 Sep 2024

No difference in health outcomes between 24-hour and 15-hour oxygen therapy

There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden.

12 Sep 2024

New AI imaging technique enhances retinal disorder diagnosis

Population-based studies have shown retinal disorders are the most common cause of irreversible blindness in developed countries and the second most common cause of blindness after cataracts in developing countries.

12 Sep 2024

New vaccine candidate shows promise for protecting against Lassa fever

Researchers from Thomas Jefferson University and the University of Maryland Baltimore, in collaboration with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) and the Geneva Foundation, have developed a promising new vaccine candidate that protects against Lassa fever.

12 Sep 2024

Prolonged exposure to wildfire smoke increases mental illness risk in youth

Each additional day of exposure to wildfire smoke and other extreme forms of dirty air boosts risk of mental illness in youth a little more, according to a new University of Colorado Boulder study of 10,000 9 to 11 year olds.

12 Sep 2024

Nucleophagy identified as key DNA repair mechanism in cancer treatments

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients undergoing colorectal cancer treatments.

12 Sep 2024

Concept neurons and location cells play key roles in memory formation

Certain nerve cells in the brain become active whenever they are confronted with different images or the name of a specific person or the identity of an object. They are highly selective and do not react to other people or objects.

12 Sep 2024

High-dose amphetamine use linked to increased risk of psychosis or mania

Prescribing rates for stimulants that treat attention-deficit/hyperactivity disorder (ADHD) have increased significantly over the past decade, with some of the largest increases reported during the COVID-19 pandemic.

12 Sep 2024

Shorter leukocyte telomere length and greater LTL attrition tied to cystic fibrosis severity

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 16 on August 29, 2024, entitled, "Leukocyte telomere length and attrition in association with disease severity in cystic fibrosis patients."

12 Sep 2024

In Montana, 911 calls reveal impact of heat waves on rural seniors

Missoula is one of Montana's largest cities but is surrounded by rural mountain communities where cattle ranching is king.

12 Sep 2024

Machine learning reveals sleep quality and anxiety as major predictors of depression

Researchers applied machine learning to predict depressive symptoms, revealing sleep quality and anxiety as key factors across diverse populations and datasets.

12 Sep 2024

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Hospital News and Research

NIH funds new research to combat emerging viruses

AI-powered treatment allocation improves public health outcomes

Scientists develop novel technique to combat T cell exhaustion

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Real-world data reveals factors associated with long-term weight loss in obesity

New drug shows strong activity against brain metastases in HER2-positive breast cancer

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

National survey reveals vaccine hesitancy ahead of flu and COVID-19 season

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Significant global cardiovascular risk linked to high lipoprotein(a) levels

No difference in health outcomes between 24-hour and 15-hour oxygen therapy

New AI imaging technique enhances retinal disorder diagnosis

New vaccine candidate shows promise for protecting against Lassa fever

Prolonged exposure to wildfire smoke increases mental illness risk in youth

Nucleophagy identified as key DNA repair mechanism in cancer treatments

Concept neurons and location cells play key roles in memory formation

High-dose amphetamine use linked to increased risk of psychosis or mania

Shorter leukocyte telomere length and greater LTL attrition tied to cystic fibrosis severity

In Montana, 911 calls reveal impact of heat waves on rural seniors

Machine learning reveals sleep quality and anxiety as major predictors of depression

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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