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Faecalibacterium prausnitzii and human intestinal health.

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Affiliations

  • 1. INRA, Commensal and Probiotics-Host Interactions Laboratory, UMR 1319 Micalis, F-78350 Jouy-en-Josas, France.
      Authors
    • Miquel S 1
    (1 author)

ORCIDs linked to this article

Current Opinion in Microbiology, 01 Jun 2013, 16(3):255-261
https://doi.org/10.1016/j.mib.2013.06.003 PMID: 23831042 

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Abstract 

Faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. Over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically active commensal bacterium as a component of the healthy human microbiota. Changes in the abundance of F. prausnitzii have been linked to dysbiosis in several human disorders. Administration of F. prausnitzii strain A2-165 and its culture supernatant have been shown to protect against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in mice. Here, we discuss the role of F. prausnitzii in balancing immunity in the intestine and the mechanisms involved.

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Read article at publisher's site: https://doi.org/10.1016/j.mib.2013.06.003

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Funding 

Funders who supported this work.

Biovitis

    Burgundy Region

      Conseil Général 21

        FEDER

          French FUI

            Grand Dijon

              Merck Médication Familiale