Abstract
Free full text
Inhaling and lung cancer: an anomaly explained.
Abstract
An objective index of inhaling cigarette smoke based on carboxyhaemoglobin concentrations and the carbon monoxide yields of cigarettes was used to investigate possible systematic differences in the extent of inhaling among light and heavy smokers when classified according to their self described inhaling habits. A total of 2108 men who smoked cigarettes were studied. Heavy smokers (20 or more cigarettes a day) had a higher average inhaling index than light smokers (fewer than 20 cigarettes a day) both among those who said that they inhaled and among those who said that they did not. This observation, together with indirect evidence that heavy smokers who inhale deeply may to some extent avoid depositing smoke condensate on their main bronchial epithelium, explains a hitherto unresolved anomaly--namely, that the risk of lung cancer is less among heavy cigarette smokers who say that they inhale than it is among those who say that they do not inhale.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (633K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Doll R, Peto R. Mortality in relation to smoking: 20 years' observations on male British doctors. Br Med J. 1976 Dec 25;2(6051):1525–1536. [Europe PMC free article] [Abstract] [Google Scholar]
- Higenbottam T, Shipley MJ, Rose G. Cigarettes, lung cancer, and coronary heart disease: the effects of inhalation and tar yield. J Epidemiol Community Health. 1982 Jun;36(2):113–117. [Europe PMC free article] [Abstract] [Google Scholar]
- Wald N, Idle M, Bailey A. Carboxyhaemoglobin levels and inhaling habits in cigarette smokers. Thorax. 1978 Apr;33(2):201–206. [Europe PMC free article] [Abstract] [Google Scholar]
- Wald NJ, Idle M, Boreham J, Bailey A. Inhaling habits among smokers of different types of cigarette. Thorax. 1980 Dec;35(12):925–928. [Europe PMC free article] [Abstract] [Google Scholar]
- DOLL R, HILL AB. A study of the aetiology of carcinoma of the lung. Br Med J. 1952 Dec 13;2(4797):1271–1286. [Europe PMC free article] [Abstract] [Google Scholar]
Associated Data
Articles from British Medical Journal (Clinical Research Ed.) are provided here courtesy of BMJ Publishing Group
Full text links
Read article at publisher's site: https://doi.org/10.1136/bmj.287.6401.1273
Read article for free, from open access legal sources, via Unpaywall:
https://www.bmj.com/content/bmj/287/6401/1273.full.pdf
Citations & impact
Impact metrics
Citations of article over time
Smart citations by scite.ai
Explore citation contexts and check if this article has been
supported or disputed.
https://scite.ai/reports/10.1136/bmj.287.6401.1273
Article citations
Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC.
Cancer Epidemiol Biomarkers Prev, 20(10):2250-2261, 23 Aug 2011
Cited by: 41 articles | PMID: 21862624 | PMCID: PMC5697736
[Female lung cancer trends, staging and histology in Hérault, France].
Rev Epidemiol Sante Publique, 57(4):275-284, 10 Jul 2009
Cited by: 0 articles | PMID: 19596531
Time trend and the age-period-cohort effect on the incidence of histologic types of lung cancer in Connecticut, 1960-1989.
Cancer, 74(5):1556-1567, 01 Sep 1994
Cited by: 63 articles | PMID: 8062189
Female mortality trends in Spain due to tumors associated with tobacco smoking.
Cancer Causes Control, 4(6):539-545, 01 Nov 1993
Cited by: 8 articles | PMID: 8280831
Research on smoking and lung cancer: a landmark in the history of chronic disease epidemiology.
Yale J Biol Med, 63(1):29-46, 01 Jan 1990
Cited by: 20 articles | PMID: 2192501 | PMCID: PMC2589239
Similar Articles
To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.
Inhaling habits among smokers of different types of cigarette.
Thorax, 35(12):925-928, 01 Dec 1980
Cited by: 31 articles | PMID: 7268668 | PMCID: PMC471416
Carboxyhaemoglobin levels and inhaling habits in cigarette smokers.
Thorax, 33(2):201-206, 01 Apr 1978
Cited by: 23 articles | PMID: 663879 | PMCID: PMC470870
Prospective study of effect of switching from cigarettes to pipes or cigars on mortality from three smoking related diseases.
BMJ, 314(7098):1860-1863, 01 Jun 1997
Cited by: 41 articles | PMID: 9224127 | PMCID: PMC2126967
The changing cigarette, 1950-1995.
J Toxicol Environ Health, 50(4):307-364, 01 Mar 1997
Cited by: 382 articles | PMID: 9120872
Review
Carboxyhemoglobin and thiocyanate as biomarkers of exposure to carbon monoxide and hydrogen cyanide in tobacco smoke.
Exp Toxicol Pathol, 58(2-3):101-124, 14 Sep 2006
Cited by: 63 articles | PMID: 16973339
Review
