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Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage

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Europe PubMed Central

PubMed publication ID

6 August 2017

Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage (English)

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Europe PubMed Central

PubMed publication ID

6 August 2017

Alzheimer's disease

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mitochondrial DNA

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author name string

Marcus J Calkins

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

P Hemachandra Reddy

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

27 April 2011

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Europe PubMed Central

PubMed publication ID

6 August 2017

Biochimica et Biophysica Acta

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Europe PubMed Central

PubMed publication ID

6 August 2017

1812

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Europe PubMed Central

PubMed publication ID

6 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1182-1189

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3143239/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Mitochondria as a therapeutic target for aging and neurodegenerative diseases

1 reference

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

1 reference

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

1 reference

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Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure

1 reference

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13 July 2018

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

1 reference

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13 July 2018

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

1 reference

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Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases

1 reference

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

1 reference

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Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

1 reference

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1 reference

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Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons

1 reference

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13 July 2018

Mitochondrial DNA (mtDNA) biogenesis: visualization and duel incorporation of BrdU and EdU into newly synthesized mtDNA in vitro.

1 reference

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13 July 2018

Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities

1 reference

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13 July 2018

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

1 reference

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13 July 2018

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

1 reference

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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

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Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model

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Mitochondrial biogenesis in the axons of vertebrate peripheral neurons

1 reference

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Mitochondrial fragmentation in neurodegeneration

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1 reference

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13 July 2018

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

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Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics

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Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

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Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

1 reference

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Cell-permeable, mitochondrial-targeted, peptide antioxidants

1 reference

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13 July 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

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Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion

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Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons.

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ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

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Replication of mitochondrial DNA occurs throughout the mitochondria of cultured human cells

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Mitochondrial abnormalities in Alzheimer's disease.

1 reference

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1 reference

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12 December 2020

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10.1016/J.BBADIS.2011.04.006

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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