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Neuroendocrine Tumors of the Female Reproductive Tract: A Literature Review

J Pathol Transl Med. 2015 Oct 13;49(6):450-461. doi: 10.4132/jptm.2015.09.20. Online ahead of print.

Abstract

Neuroendocrine tumors of the female reproductive tract are a heterogeneous group of neoplasms that display various histologic findings and biologic behaviors. In this review, the classification and clinicopathologic characteristics of neuroendocrine tumors of the female reproductive tract are described. Differential diagnoses are discussed, especially for non-neuroendocrine tumors showing high-grade nuclei with neuroendocrine differentiation. This review also discusses recent advances in our pathogenetic understanding of these disorders.

Keywords: Carcinoma, neuroendocrine; Female reproductive tract; Gynecologic tract; Neuroendocrine tumors.