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Expanded Geographic Distribution and Clinical Characteristics of Ehrlichia ewingii Infections, United States

Emerg Infect Dis. 2016 May;22(5):862-5. doi: 10.3201/eid2205.152009.

Abstract

Ehrlichiosis is a bacterial zoonosis, spread through the bites of infected ticks, that is most commonly caused in the United States by infection with the bacterium Ehrlichia chaffeensis. We retrospectively reviewed samples from an 18-month study of ehrlichiosis in the United States and found that E. ewingii was present in 10 (9.2%) of 109 case-patients with ehrlichiosis, a higher rate of infection with this species than had previously been reported. Two patients resided in New Jersey and Indiana, where cases have not been reported. All patients with available case histories recovered. Our study suggests a higher prevalence and wider geographic distribution of E. ewingii in the United States than previous reports have indicated.

Keywords: Ehrlichia chaffeensis; Ehrlichia ewingii; Ehrlichiosis; United States; bacteria; geographic distribution; ticks; vector-borne infections; zoonoses.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Animal Diseases / epidemiology
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Antibodies, Bacterial / immunology
  • Ehrlichia / classification*
  • Ehrlichia / genetics
  • Ehrlichia / immunology
  • Ehrlichiosis / diagnosis*
  • Ehrlichiosis / drug therapy
  • Ehrlichiosis / epidemiology*
  • Ehrlichiosis / microbiology
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Male
  • Population Surveillance
  • Prevalence
  • RNA, Ribosomal, 16S / genetics
  • Retrospective Studies
  • Treatment Outcome
  • United States / epidemiology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Antibodies, Bacterial
  • RNA, Ribosomal, 16S