A mandated shelter-in-place and other restrictions associated with the coronavirus disease pandemic precipitated a decline in tuberculosis diagnoses in San Francisco, California, USA. Several months into the pandemic, severe illness resulting in hospitalization or death increased compared with prepandemic levels, warranting heightened vigilance for tuberculosis in at-risk populations.
Keywords: COVID-19; California; SARS-CoV-2; San Francisco; TB; United States; bacteria; coronavirus disease; deaths; epidemiology; hospitalizations; mortality rate; respiratory diseases; respiratory infections; severe acute respiratory syndrome coronavirus 2; tuberculosis and other mycobacteria; viruses; zoonoses.