PGF

PGF
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FZV, 1RV6
Dynodwyr
Cyfenwau	PGF, D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760, Placental growth factor, PIGF
Dynodwyr allanol	OMIM: 601121 HomoloGene: 1978 GeneCards: PGF
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • growth factor activity • vascular endothelial growth factor receptor binding • chemoattractant activity • vascular endothelial growth factor receptor 3 binding Cydrannau o'r gell • bilen • extracellular region • extracellular space Prosesau biolegol • cell differentiation • female pregnancy • cell-cell signaling • regulation of morphogenesis of a branching structure • sprouting angiogenesis • multicellular organism development • branching involved in ureteric bud morphogenesis • cellular response to hormone stimulus • animal organ regeneration • positive regulation of cell population proliferation • positive regulation of cell division • GO:0072468 signal transduction • angiogenesis • response to hypoxia • positive regulation of endothelial cell proliferation • positive regulation of angiogenesis • vascular endothelial growth factor receptor signaling pathway • induction of positive chemotaxis • positive regulation of mast cell chemotaxis • regulation of signaling receptor activity • positive regulation of protein phosphorylation • vascular endothelial growth factor signaling pathway • positive chemotaxis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5228	n/a
Ensembl	ENSG00000119630	n/a
UniProt	P49763	n/a
RefSeq (mRNA)	NM_002632 NM_001207012 NM_001293643	n/a
RefSeq (protein)	NP_001193941 NP_001280572 NP_002623	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PGF yw PGF a elwir hefyd yn Placental growth factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q24.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PGF.

• PGFL
• PIGF
• PLGF
• PlGF-2
• D12S1900
• SHGC-10760

Llyfryddiaeth

• "Placental Growth Factor Is Secreted by the Human Endometrium and Has Potential Important Functions during Embryo Development and Implantation. ". PLoS One. 2016. PMID 27711226.
• "Fluid Shear Stress Promotes Placental Growth Factor Upregulation in Human Syncytiotrophoblast Through the cAMP-PKA Signaling Pathway. ". Hypertension. 2016. PMID 27698065.
• "Placental Growth Factor in Bladder Cancer Compared to the Diagnostic Accuracy and Prognostic Performance of Vascular Endothelial Growth Factor A. ". Anticancer Res. 2018. PMID 29277778.
• "Hypoxia-induced responses by endothelial colony-forming cells are modulated by placental growth factor. ". Stem Cell Res Ther. 2016. PMID 27899144.
• "The relationship between maternal placental growth factor levels and intrapartum fetal compromise.". Placenta. 2016. PMID 27871474.