POLB
Gwedd
Protein sy'n cael ei godio yn y corff dynol gan y genyn POLB yw POLB a elwir hefyd yn DNA polymerase beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p11.21.[2]
Llyfryddiaeth
[golygu | golygu cod]- "Unencumbered Pol β lyase activity in nucleosome core particles. ". Nucleic Acids Res. 2017. PMID 28911106.
- "A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells. ". J Biol Chem. 2017. PMID 28684413.
- "POLB: A new role of DNA polymerase beta in mitochondrial base excision repair. ". DNA Repair (Amst). 2017. PMID 29129598.
- "Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. ". Nucleic Acids Res. 2017. PMID 28973450.
- "Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity.". Biochemistry. 2017. PMID 28945359.