On Quality Control Measures in Genome-Wide Association Studies: A Test to Assess the Genotyping Quality of Individual Probands in Family-Based Association Studies and an Application to the HapMap Data
Figure 4
Simulation results with LD—minor allele frequencies drawn from a truncated Beta (2,8) distribution.
Average standardized transmission test over 1,000 replications for varying levels of genotype error and SNP chip sizes in the presence of LD. Each graph displays results for a single genotype error model from Figure 1. (A–F) correspond to Models 1–6, respectively. Legends are different in each graph.