Journal of the Serbian Chemical Society 2000 Volume 65, Issue 2, Pages: 95-102
https://doi.org/10.2298/JSC0002095E
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Synthesis and biological activity of some heterocyclic compounds containing quinoxaline and coumarin moieties
El-Deen I.M. (Suez Canal University, Faculty of Education, Port-Said, Egypt)
El-Fattah Abd M.E. (Suez Canal University, Faculty of Science, Chemistry Department, Ismailia, Egypt)
2,3-Dichloroquinoxaline (2) condensed with 7,8-dihydroxy-4-methylcoumarin to
give the 1,4-dioxane derivative 4. 2.3-Dichloroquinoxaline (2) reacted with
4-hydroxycoumarin, 7-hydroxy-4-methylcoumarin and acyl hydrazide 13 to
give either the 2,3-(dicoumarin-4-yloxy)quinoxaline (6) or the
2,3-di-(4-methylcoumarin-7-yloxy)quinoxaline (7) or the
2-chloro-3-(coumarin-4-yloxy)quinoxaline (8) or the 2-chloro-3-(4-
methylcoumarin-7-yloxy) quinoxaline (9) or the ditriazoloquinoxaline 14 or
the oxadiazinoquinoxaline 16, depending on the relative ratios of the
reactants and the reaction conditions.
Keywords: 2,3-dichloroquinoxaline, reaction with coumarin derivatives