Journal of the Serbian Chemical Society 2005 Volume 70, Issue 3, Pages: 319-327
https://doi.org/10.2298/JSC0503319K
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Synthesis of α-amino amides via α-amino imidoylbenzotriazoles
Katritzky Alan R. (University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA)
Mohapatra Prabhu P. (University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA)
Singh Shailendra (University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA)
Clemens Nicole (University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA)
Kirichenko Kostyantyn (University of Florida - Center for Heterocyclic Compounds - Department of Chemistry, Gainesville, Florida USA)
Reactions of isonitriles 11a-c with N-(α-aminoalkyl)benzotriazoles 10a-k afford N-(α-aminoimidoyl)benzotriazoles 12a-q which on hydrolysis by dilute hydrochloric acid gave α-amino amides 14a-j.
Keywords: α-aminoalkyl benzotriazoles, imidoylbenzotriazoles, α-amino amides.