OR10K1
OR10K1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | OR10K1, OR1-6, olfactory receptor family 10 subfamily K member 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | HomoloGene: 84605; GeneCards: OR10K1; OMA:OR10K1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Olfactory receptor 10K1 is a protein that in humans is encoded by the OR10K1 gene.[3]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]
Amino acid sequence
[edit]MEQVNKTVVR EFVVLGFSSL ARLQQLLFVI FLLLYLFTLG TNAIIISTIV LDRALHTPMY FFLAILSCSE ICYTFVIVPK MLVDLLSQKK TISFLGCAIQ MFSFLFFGSS HSFLLAAMGY DRYMAICNPL RYSVLMGHGV CMGLMAAACA CGFTVSLVTT SLVFHLPFHS SNQLHHFFCD ISPVLKLASQ HSGFSQLVIF MLGVFALVIP LLLILVSYIR IISAILKIPS SVGRYKTFST CASHLIVVTV HYSCASFIYL RPKTNYTSSQ DTLISVSYTI LTPLFNPMIY SLRNKEFKSA LRRTIGQTFY PLS
[4]
See also
[edit]References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000173285 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: OR10K1 olfactory receptor, family 10, subfamily K, member 1".
- ^ "ORDB: Chemosensory Receptors - ORL3001".
Further reading
[edit]- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
External links
[edit]- OR10K1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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