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    Jonas Capelli

    Introduction: Currently, no method is considered effective for the evaluation of digital models in the Certification Examination of the Brazilian Board of Orthodontics (BBO), considering the parameters of the currently used manual method.... more
    Introduction: Currently, no method is considered effective for the evaluation of digital models in the Certification Examination of the Brazilian Board of Orthodontics (BBO), considering the parameters of the currently used manual method. Objective: Thus, the aim of this study is to verify the reliability of an evaluation method for digital models that could be used in the BBO exam, compared to the gold standard. Methods: Measurements were performed by five previously calibrated examiners. Samples of ten sets of plaster models of the final phase of orthodontic treatment were measured using a manual method (Objective Grading System, OGS). These models were digitized using a 3D scanner and exported to Geomagic Qualify software, in which the measurements were made with the proposed digital method. These measurements were repeated using five models, after fifteen days. The intra-examiner performance with this method was analyzed with a paired t-test, whereas the inter-examiner analysis ...
    Gingival crevicular fluid (GCF) is a biological exudate and quantification of its constituents is a current method to identify specific biomarkers with reasonable sensitivity for several biological events. Studies are being performed to... more
    Gingival crevicular fluid (GCF) is a biological exudate and quantification of its constituents is a current method to identify specific biomarkers with reasonable sensitivity for several biological events. Studies are being performed to evaluate whether the GCF biomarkers in growing subjects reflect both the stages of individual skeletal maturation and the local tissue remodeling triggered by orthodontic force. Present evidence is still little regarding whether and which GCF biomarkers are correlated with the growth phase (mainly pubertal growth spurt), while huge investigations have been reported on several GCF biomarkers (for inflammation, tissue damage, bone deposition and resorption, and other biological processes) in relation to the orthodontic tooth movement. In spite of these investigations, the clinical applicability of the method is still limited with further data needed to reach a full diagnostic utility of specific GCF biomarkers in orthodontics. Future studies are warran...
    To analyze histologic findings of bone remodeling at the time of surgery and 90 days later at corticotomized and noncorticotomized sites. Eight adult patients with bilaterally inclined mandibular molars were included in this split-mouth... more
    To analyze histologic findings of bone remodeling at the time of surgery and 90 days later at corticotomized and noncorticotomized sites. Eight adult patients with bilaterally inclined mandibular molars were included in this split-mouth study. Corticotomy was performed on the test side, and bone was harvested on both mandibular hemi-arches. Bone blocks were shipped to Forsyth Institute lab (Boston, Mass). After surgery, cantilevers were activated to upright inclined mandibular molars on both sides. Approximately 90 days after surgery, new mandibular bone blocks were harvested from test and control sites. Histologic analyses were performed on both groups (test and control sides) at two time points: baseline (T0) and 90 days after surgery (T90). Bone blocks were stained with hematoxylin and eosin, and Masson's trichrome. The protocols enabled screening of new bone formation and collagen in mineralized and nonmineralized connective tissue. Outcomes were compared using a clustered g...
    This randomized split-mouth study was aimed at evaluating whether an orthodontic appliance per se or orthodontic tooth movement can induce detectable changes in gingival crevicular fluid (GCF) volume, and thus whether GCF volume is a... more
    This randomized split-mouth study was aimed at evaluating whether an orthodontic appliance per se or orthodontic tooth movement can induce detectable changes in gingival crevicular fluid (GCF) volume, and thus whether GCF volume is a predictable biomarker for tissue remodelling incident to orthodontic tooth movement. Sixteen healthy orthodontic patients (7 females and 9 males; mean age, 17.7 years; range, 13-27 years) with the need for extraction of the first upper premolars were enrolled. One randomly chosen maxillary canine was subjected to a distalizing force by a 0.017 × 0.025 inch titanium-molybdenum alloy archwire and considered as the test tooth (TT). The contralateral canine, which was not subjected to any force but was included in an orthodontic appliance, was used as a control (CT). GCF sampling was performed at both mesial and distal sites of the CTs and TTs at baseline, immediately before applying the orthodontic appliance, and after 1 hour, 24 hours, and 7, 14, and 21 days. A Periotron was used to measure the GCF volume. A modest but significant increase in the GCF volume over time was seen in both the CTs (mesial sites) and the TTs (both mesial and distal sites) with no differences between the experimental teeth. Subclinical tissue inflammation consequent to the placement of the orthodontic appliance might be responsible for these GCF volume changes. The GCF volume does not appear to be a reliable biomarker for tissue remodelling during orthodontic treatment.
    ABSTRACT a b s t r a c t Background: This randomized study aimed at evaluating whether orthodontic tooth movement can induce detectable changes in gingival crevicular fluid (GCF) volume in patients with controlled peri-odontal disease.... more
    ABSTRACT a b s t r a c t Background: This randomized study aimed at evaluating whether orthodontic tooth movement can induce detectable changes in gingival crevicular fluid (GCF) volume in patients with controlled peri-odontal disease. Methods: Ten patients (8 women and 2 men, mean age of 46.2 AE 10.4 years) with controlled periodontal disease and flared incisors were included in the study. Gingival crevicular fluid samples were collected from the mid-palatal and mid-lingual sites of 1 central and 1 lateral incisor of each arch from each patient for a total of 4 individual samples per patient. These sites were selected to represent the pressure side of the applied forces (movement sites). Samples obtained from the arch without the appliance served as controls. Samples were collected at 1 week before orthodontic activation (e7d); right before the orthodontic appliance activation (0); after 1 and 24 hours; and after 7, 14, and 21 days of the acti-vation. Filter paper strips were used in combination with a Periotron for GCF volume measurements. All patients received hygiene instructions and a kit containing toothbrush, fluoride dentifrice, and gluconate chlorhexidine 0.12% mouthwash to be used during all experiment. Results: There were no statistically significant differences over time in the GCF volume for any samples from the two groups. When the two groups were compared, there were no statistically significant differences in the GCF volume at any time point. Conclusions: The GCF volume could not be associated to orthodontic movement in teeth with controlled periodontal disease. Ó 2012 World Federation of Orthodontists.
    This is a treatment report of a patient with an anterior open bite and predominance of vertical growth. Multiloop edgewise archwire (MEAW) mechanics were used and resulted in an efficient bite closure and good occlusion. For retention, a... more
    This is a treatment report of a patient with an anterior open bite and predominance of vertical growth. Multiloop edgewise archwire (MEAW) mechanics were used and resulted in an efficient bite closure and good occlusion. For retention, a bonded 3-3 retainer was used in the mandible whereas a wraparound retainer was employed in the maxilla.© 2009 Quintessence Publishing Co, Inc. All Rights Reserved
      To evaluate age- and gender-related changes in the soft tissues, incisors, and gingival display during rest, speech, and posed smile.   A total of 265 participants (122 men, 143 women) ranging in age from 19 years to 60 years were... more
      To evaluate age- and gender-related changes in the soft tissues, incisors, and gingival display during rest, speech, and posed smile.   A total of 265 participants (122 men, 143 women) ranging in age from 19 years to 60 years were recruited for this study. Participants were divided into one of the following four age groups: 19 to 24 years, 25 to 34 years, 35 to 44 years, and 45 to 60 years. Image capture was performed using standardized videographic methods. Each video produced pictures where measurements were performed: rest, speech, and smile positions.   A statistically significant gender dimorphism was apparent in most of the variables. There was a significant increase in the upper lip length and lip commissures height with aging and more markedly in men. A greater exposure of mandibular incisor with increasing age was a feature in both genders. With increasing age there was a significant decrease in maxillary incisor display, especially for men.   After 25 years of age there is significant difference in the aging process between men and women. Gingival and maxillary incisor display during speech and smile is a youthful and feminine characteristic.
    Resumo: A má oclusão de Classe III é caracterizada por uma discrepância esquelética ântero-posterior, acompanhada ou não por alterações verticais, mas geralmente envolvendo também alterações transversais das bases ósseaas. Apesar da baixa... more
    Resumo: A má oclusão de Classe III é caracterizada por uma discrepância esquelética ântero-posterior, acompanhada ou não por alterações verticais, mas geralmente envolvendo também alterações transversais das bases ósseaas. Apesar da baixa ...
    Objective: To examine levels of matrix metalloproteinases (MMPs)-1, -2, -3, -7, -8, -12, and -13 in the gingival crevicular fluid (GCF) of periodontally compromised teeth at different time points during orthodontic movement. Materials and... more
    Objective: To examine levels of matrix metalloproteinases (MMPs)-1, -2, -3, -7, -8, -12, and -13 in the gingival crevicular fluid (GCF) of periodontally compromised teeth at different time points during orthodontic movement. Materials and Methods: Ten controlled periodontitis subjects were submitted to orthodontic treatment. One dental arch was subjected to orthodontic movement, and teeth in the opposite arch were used as controls. GCF samples were collected from the lingual sites of two movement and two control incisors 1 week before orthodontic activation (-7 d), immediately after orthodontic activation, and after 1 hour, 24 hours, and 7, 14, and 21 days. Multiplexed bead immunoassay was used to measure MMPs in GCF. Data were analyzed using Friedman and Wilcoxon statistical tests. Results: The only significant change found over time was in the levels of MMP-1 in the movement group (P < .05). When the two groups were compared after activation, the only statistically significant difference found was in levels of MMP-12 24 hours after activation (P < .05). Conclusions: Our findings suggested that the orthodontic movement of periodontally compromised teeth without active pockets did not result in significant changes in the GCF levels of MMPs.
    página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 331283. Autor: Sekito, Pepita Sampaio Cardoso; Capelli Júnior, Jonas; Almeida, Marco Antonio de Oliveira; Boasquevisque, Edson... more
    página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 331283. Autor: Sekito, Pepita Sampaio Cardoso; Capelli Júnior, Jonas; Almeida, Marco Antonio de Oliveira; Boasquevisque, Edson Mendes. ...
    RESUMO INTRODUÇÃO: a má oclusão de Classe III é caracterizada por uma discrepância esquelética ântero-posterior, podendo ou não estar acompanhada de alterações verticais, mas comumente apresenta alterações transversais associadas. O... more
    RESUMO INTRODUÇÃO: a má oclusão de Classe III é caracterizada por uma discrepância esquelética ântero-posterior, podendo ou não estar acompanhada de alterações verticais, mas comumente apresenta alterações transversais associadas. O aspecto facial fica ...
    The aims of this study were to evaluate the changes in the facial profile related to maxillary incisor retraction and to check for correlations between changes in the lip and changes in the positions of the teeth and alveolar bone during... more
    The aims of this study were to evaluate the changes in the facial profile related to maxillary incisor retraction and to check for correlations between changes in the lip and changes in the positions of the teeth and alveolar bone during orthodontic treatment. Initial and final lateral cephalometric radiographs of 25 nongrowing Brazilian patients were selected for this study. All patients initially presented with Class I or II malocclusions and had their maxillary incisors retracted at least 2 mm during orthodontic treatment. Changes in lip position, length, and width, as well as changes in the positions of the alveolar bones and incisors, were calculated. Statistically significant differences from pretreatment to posttreatment were observed for all measurements except for upper lip length and point A. A high correlation was demonstrated between changes in the lower lip sulcus and point B and between changes in the lower lip sulcus and the mandibular incisor. Changes in the maxillary and mandibular incisors did not show a high correlation to the total lip changes, but high correlation coefficients were obtained when the changes in lip width were excluded from the total lip changes. In other words, changes in lip width tended to mask the changes in lip position caused by retraction of the maxillary incisors.
    The purpose of this study was to evaluate the tooth size discrepancies in patients of Rio de Janeiro State University Orthodontic Clinic. The sample was composed of 161 patients, which fulfilled the including criteria. Mesiodistal width... more
    The purpose of this study was to evaluate the tooth size discrepancies in patients of Rio de Janeiro State University Orthodontic Clinic. The sample was composed of 161 patients, which fulfilled the including criteria. Mesiodistal width of all permanent teeth were measured, from first left molar to first right molar, in both arches. The Bolton's discrepancy ratio was calculated for each set of models. The means for overall and anterior ratios were obtained for the whole sample, also evaluating differences between sexes and malocclusion (Angle's Class I, Class II and Class III). The values found were compared to Bolton's means. The overall and anterior ratios demonstrated no significant differences between sexes. No significant differences were found among the means obtained for each malocclusion group. These results suggested no influence of malocclusion status in the intermaxillary tooth size ratios of the studied sample. However, when comparing the sample's means t...
    This randomized split-mouth study was aimed at evaluating whether an orthodontic appliance per se or orthodontic tooth movement can induce detectable changes in gingival crevicular fluid (GCF) volume, and thus whether GCF volume is a... more
    This randomized split-mouth study was aimed at evaluating whether an orthodontic appliance per se or orthodontic tooth movement can induce detectable changes in gingival crevicular fluid (GCF) volume, and thus whether GCF volume is a predictable biomarker for tissue remodelling incident to orthodontic tooth movement. Materials and Methods: Sixteen healthy orthodontic patients (7 females and 9 males; mean age, 17.7 years; range, 13-27 years) with the need for extraction of the first upper premolars were enrolled. One randomly chosen maxillary canine was subjected to a distalizing force by a 0.017 × 0.025 inch titanium-molybdenum alloy archwire and considered as the test tooth (TT). The contralateral canine, which was not subjected to any force but was included in an orthodontic appliance, was used as a control (CT). GCF sampling was performed at both mesial and distal sites of the CTs and TTs at baseline, immediately before applying the orthodontic appliance, and after 1 hour, 24 hou...
    This patient report describes the treatment of a 10-year-old female with complete transposition of her impacted mandibular canines and lateral incisors. The patient had a Class I occlusion, and her mandibular lateral incisors were in... more
    This patient report describes the treatment of a 10-year-old female with complete transposition of her impacted mandibular canines and lateral incisors. The patient had a Class I occlusion, and her mandibular lateral incisors were in crossbite with the maxillary central incisors. The treatment objectives were to create space for the impacted canines and align them with the incisors, one of which was extracted. After treatment, the appearance of the patient's teeth was improved, the occlusion was preserved, and overjet and overbite were corrected.
    Objective: To examine levels of matrix metalloproteinases (MMPs)-1, -2, -3, -7, -8, -12, and -13 in the gingival crevicular fluid (GCF) of periodontally compromised teeth at different time points during orthodontic movement. Materials and... more
    Objective: To examine levels of matrix metalloproteinases (MMPs)-1, -2, -3, -7, -8, -12, and -13 in the gingival crevicular fluid (GCF) of periodontally compromised teeth at different time points during orthodontic movement. Materials and Methods: Ten controlled periodontitis subjects were submitted to orthodontic treatment. One dental arch was subjected to orthodontic movement, and teeth in the opposite arch were used as controls. GCF samples were collected from the lingual sites of two movement and two control incisors 1 week before orthodontic activation (-7 d), immediately after orthodontic activation, and after 1 hour, 24 hours, and 7, 14, and 21 days. Multiplexed bead immunoassay was used to measure MMPs in GCF. Data were analyzed using Friedman and Wilcoxon statistical tests. Results: The only significant change found over time was in the levels of MMP-1 in the movement group (P < .05). When the two groups were compared after activation, the only statistically significant difference found was in levels of MMP-12 24 hours after activation (P < .05). Conclusions: Our findings suggested that the orthodontic movement of periodontally compromised teeth without active pockets did not result in significant changes in the GCF levels of MMPs.
    Patients with juvenile idiopathic arthritis (JIA) can have alterations in bone metabolism and skeletal growth, as well as damage to the temporomandibular joint (TMJ), which can generate extra and/or intraoral alterations, resulting in... more
    Patients with juvenile idiopathic arthritis (JIA) can have alterations in bone metabolism and skeletal growth, as well as damage to the temporomandibular joint (TMJ), which can generate extra and/or intraoral alterations, resulting in craniofacial disorders. Our goal is to carry out a review of the literature on orofacial alterations in patients with JIA. Among the orofacial disorders in patients with JIA, alterations in mandibular growth, caused by dysfunctions in the TMJ region, seem highly prevalent in these patients. The most often found alterations are: retrognathia, micrognathia, anterior open bite, dental crowding, facial asymmetry and mouth opening limitation. Thus, the rheumatologist becomes a key agent in the early detection of these disorders, helping with patient referral to a dentist. The diagnosis, in turn, should be performed by the orthodontist, using clinical examination and imaging methods, allowing early treatment and a favorable prognosis. TMJ disorders should be...
    Page 1. R Dental Press Ortodon Ortop Facial 151 Maringá, v. 11, n. 5, p. 151-158, set./out. 2006 Avaliação da superfície da porcelana após a descolagem de braquetes ortodônticos André Moreira Mattos*, Jonas Capelli Júnior** ...
    INTRODUCTION: Class III malocclusion is characterized by an anterior-posterior skeletal discrepancy that may or may not be combined with vertical alterations, but it commonly presents transverse disharmony associated. The facial aspect is... more
    INTRODUCTION: Class III malocclusion is characterized by an anterior-posterior skeletal discrepancy that may or may not be combined with vertical alterations, but it commonly presents transverse disharmony associated. The facial aspect is affected in these patients, ...
    Matrix metalloproteinases (MMPs) and monocyte chemoattractants are key modulators of the biological mechanisms triggered in the periodontium by mechanical forces. The gingival crevicular fluid (GCF) provides a non-invasive method to... more
    Matrix metalloproteinases (MMPs) and monocyte chemoattractants are key modulators of the biological mechanisms triggered in the periodontium by mechanical forces. The gingival crevicular fluid (GCF) provides a non-invasive method to assess longitudinally the release of inflammatory mediators during orthodontic tooth movement. The goal of this study was to examine the GCF levels of MMP-3, MMP-9, and MMP-13 and of the chemokines macrophage inflammatory protein (MIP)-1β, monocyte chemoattractant protein (MCP)-1, and regulated on activation normal T cells expressed and secreted (RANTES) at different time points during orthodontic tooth movement. Fourteen subjects (three males and 11 females, 18.8 ± 4.8 years of age; range from 12 to 28 years) had their maxillary canines retracted. Thirty-second GCF samples were collected from the tension and pressure sides 7 days prior to the activation of the orthodontic appliance, on the day of activation, and after 1 and 24 hours, and 14, 21, and 80 days of constant force application. The volume of GCF was measured and samples analysed using a multiplexed bead immunoassay for the content of the six target molecules. Differences in the mean GFC volumes and mean level for each analyte over time were assessed using the Friedman test, and differences between the tension and pressure sides at each time point with the Mann-Whitney test. The mean levels of the three MMPs changed significantly over time but only at the compression side (P < 0.05, Friedman test). The GCF levels of the three chemokines were not affected by the application of mechanical stress. The levels of MMPs in GCF at the pressure side are modulated by the application of orthodontic force.