05/16/2024
Research Article
Collecting time-series data of fungal growth that captures the morphological information required for model fitting or estimating morphology-specific growth rates is prohibitively time consuming for large-scale drug testing in most microbiology laboratories.
Image credit: Guido Blokker
Current Issue April 2024
05/15/2024
Methods
The authors used artificial neural networks (ANNs) to bypass likelihood computation and approximation altogether, and demonstrate the success of this approach applied to model parameter estimation and model comparison.
Image credit: Alina Grubnyak
05/15/2024
Research Article
The authors employed mathematical modeling to study how marmoset monkeys coordinate vigilance and feeding behaviors in a situation where doing both actions simultaneously is not possible.
Image credit: Matt Flores
05/03/2024
Research Article
The authors present an agent-based simulation framework to study how individuals of groups use social information during foraging together and how this social information use shapes the collective outcome through the behavior of single individuals.
Image credit: Nellie Adamyan
04/19/2024
Research Article
Cooltools enables users to extract key features seen in 3C maps, including: the decay of contact frequency with genomic distance, plaid patterns of active and inactive compartments, domains, and dots.
04/29/2024
Research Article
The authors discuss the methodological task of building credible, data-informed decisions based on stochastic, partially observed, nonlinear dynamic models.
Image credit: Wikipedia
04/25/2024
Research Article
Intrinsically disordered regions are often involved in essential cellular functions. These sequences evolve quickly, challenging methods reliant on sequence conservation.
04/26/2024
Research Article
The authors developed an extendable multi-scale computational framework to simulate metabolic processes spanning intracellular to extracellular scales.
Image credit:
03/25/2024
Research Article
PathIntegrate is a method for integrating multi-omics datasets based on pathways, designed to exploit knowledge of biological systems and thus provide interpretable models.
Image credit: Wieder et al
03/13/2024
Research Article
The authors perform behavioral classification from calcium imaging data of the mouse cortex and investigate brain regions important for the classification.
Image credit: Aijoka, Nakai, Yamashita, and Takumi
This Collection aims to increase the coverage of computational biology-related topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.
This series of perspective articles from computational biologists in a variety of countries, offers their personal viewpoint on the history, current status, and future of computational biology in their region.
This collection aims to provide practical tutorials and background information on important computational methods used to investigate key biological questions, as well as resources for training scientists at all stages of their careers.
The Benchmarking collection help readers decide between a number of methods which are developed to solve scientific problems.
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform
Test accuracy of polymerase chain reaction methods against conventional diagnostic techniques for Cutaneous Leishmaniasis (CL) in patients with clinical or epidemiological suspicion of CL: Systematic review and meta-analysis
Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys
Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data
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