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PLoS Genetics Issue Image | Vol. 18(1) January 2022

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Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Body-wall muscles of third instar Drosophila larvae. Muscles from the Drosophila model of oculopharyngeal muscular dystrophy (top right and bottom left) are atrophied, degenerating or broken due to increased proteasome activity. See Ribot et al.

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Image Credit: Cédric Soler, Aymeric Chartier, and Martine Simonelig

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Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Body-wall muscles of third instar Drosophila larvae. Muscles from the Drosophila model of oculopharyngeal muscular dystrophy (top right and bottom left) are atrophied, degenerating or broken due to increased proteasome activity. See Ribot et al.

Download January's cover page.

Image Credit: Cédric Soler, Aymeric Chartier, and Martine Simonelig

https://doi.org/10.1371/image.pgen.v18.i01.g001