A comprehensive genetic interaction network for maintaining genome stability, as determined by a global synthetic genetic array screen in yeast (see Budd et al.).
Image Credit: The genetic network maps synthetic lethal double mutant phenotypes, and was created with the Pajek program.
Interview
Meeting a Fork in the Road: An Interview with Tom Cech
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010076
Review
Genomic Disorders: Molecular Mechanisms for Rearrangements and Conveyed Phenotypes
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010049
Research Articles
A Network of Multi-Tasking Proteins at the DNA Replication Fork Preserves Genome Stability
PLOS Genetics: published December 2, 2005 | https://doi.org/10.1371/journal.pgen.0010061
Medical Sequencing of Candidate Genes for Nonsyndromic Cleft Lip and Palate
PLOS Genetics: published December 2, 2005 | https://doi.org/10.1371/journal.pgen.0010064
Clines, Clusters, and the Effect of Study Design on the Inference of Human Population Structure
PLOS Genetics: published December 9, 2005 | https://doi.org/10.1371/journal.pgen.0010070
Species Choice for Comparative Genomics: Being Greedy Works
PLOS Genetics: published December 2, 2005 | https://doi.org/10.1371/journal.pgen.0010071
Ablation of the Sam68 RNA Binding Protein Protects Mice from Age-Related Bone Loss
PLOS Genetics: published December 16, 2005 | https://doi.org/10.1371/journal.pgen.0010074
The Flavoring Agent Dihydrocoumarin Reverses Epigenetic Silencing and Inhibits Sirtuin Deacetylases
PLOS Genetics: published December 16, 2005 | https://doi.org/10.1371/journal.pgen.0010077
Genome-Wide Associations of Gene Expression Variation in Humans
PLOS Genetics: published December 16, 2005 | https://doi.org/10.1371/journal.pgen.0010078
Differential Regulation of Strand-Specific Transcripts from Arabidopsis Centromeric Satellite Repeats
PLOS Genetics: published December 23, 2005 | https://doi.org/10.1371/journal.pgen.0010079
Harnessing Natural Diversity to Probe Metabolic Pathways
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010080
Differential Susceptibility to Hypertension Is Due to Selection during the Out-of-Africa Expansion
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010082
Accurate Prediction of the Functional Significance of Single Nucleotide Polymorphisms and Mutations in the ABCA1 Gene
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010083
Corrections
Correction: Uncoupling of Longevity and Telomere Length in C. elegans
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010081
Related Articles
Correction: Cell-Autonomous Death of Cerebellar Purkinje Neurons with Autophagy in Niemann-Pick Type C Disease
PLOS Genetics: published December 30, 2005 | https://doi.org/10.1371/journal.pgen.0010086