Flowers of the selfing plant species, C. rubella. In this issue, Brandvain et al. identify blocks of ancestry inherited from the founders of this recently derived species. With these blocks, they learn that C. rubella split from its outcrossing progenitor around 50 to 100,000 years ago, and subsequently lost much of its genetic diversity. These ancestry blocks also inform us about the number of individuals that founded C. rubella, the relaxation of purifying selection since its origin, and its spread across the globe.
Image Credit: Kim Steige
Interview
Evidence Is Evidence: An Interview with Mary-Claire King
PLOS Genetics: published September 26, 2013 | https://doi.org/10.1371/journal.pgen.1003828
Perspectives
Nucleosome Assembly Proteins Get SET to Defeat the Guardian of Chromosome Cohesion
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Genome-Wide Analysis of ZmDREB Genes and Their Association with Natural Variation in Drought Tolerance at Seedling Stage of Zea mays L
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Nebula/DSCR1 Upregulation Delays Neurodegeneration and Protects against APP-Induced Axonal Transport Defects by Restoring Calcineurin and GSK-3β Signaling
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Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage
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Whole Genome Sequencing Identifies a Deletion in Protein Phosphatase 2A That Affects Its Stability and Localization in Chlamydomonas reinhardtii
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Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids
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The Compass-like Locus, Exclusive to the Ambulacrarians, Encodes a Chromatin Insulator Binding Protein in the Sea Urchin Embryo
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A Critical Role for PDGFRα Signaling in Medial Nasal Process Development
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The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation
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A Pre-mRNA-Splicing Factor Is Required for RNA-Directed DNA Methylation in Arabidopsis
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