Lateral view image of an igf2bp3 mutant zebrafish embryo at 3 hours post-fertilisation, with β-Catenin labelled membranes (green) and nuclear DAPI (blue), showing expansion of the extra-embryonic yolk-syncytial layer. See Vong et al.
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Image Credit: Yin Ho Vong
Viewpoints
Global variation in sequencing impedes SARS-CoV-2 surveillance
PLOS Genetics: published July 15, 2021 | https://doi.org/10.1371/journal.pgen.1009620
Perspective
Taste-testing tarsi: Gustatory receptors for glucosinolates in cabbage butterflies
PLOS Genetics: published July 15, 2021 | https://doi.org/10.1371/journal.pgen.1009616
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Review
Tetrahymena meiosis: Simple yet ingenious
PLOS Genetics: published July 15, 2021 | https://doi.org/10.1371/journal.pgen.1009627
Research Articles
The H3.3K27M oncohistone antagonizes reprogramming in Drosophila
PLOS Genetics: published July 19, 2021 | https://doi.org/10.1371/journal.pgen.1009225
A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle
PLOS Genetics: published July 21, 2021 | https://doi.org/10.1371/journal.pgen.1009331
Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation
PLOS Genetics: published July 8, 2021 | https://doi.org/10.1371/journal.pgen.1009369
NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009459
Homothorax controls a binary Rhodopsin switch in Drosophila ocelli
PLOS Genetics: published July 27, 2021 | https://doi.org/10.1371/journal.pgen.1009460
The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning
PLOS Genetics: published July 1, 2021 | https://doi.org/10.1371/journal.pgen.1009475
Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009526
Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae
PLOS Genetics: published July 15, 2021 | https://doi.org/10.1371/journal.pgen.1009527
Related Articles
Mechanism underlying the DNA-binding preferences of the Vibrio cholerae and vibriophage VP882 VqmA quorum-sensing receptors
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009550
CRISPR/Cas9 modified An. gambiae carrying kdr mutation L1014F functionally validate its contribution in insecticide resistance and combined effect with metabolic enzymes
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009556
Pch2 orchestrates the meiotic recombination checkpoint from the cytoplasm
PLOS Genetics: published July 14, 2021 | https://doi.org/10.1371/journal.pgen.1009560
Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios
PLOS Genetics: published July 9, 2021 | https://doi.org/10.1371/journal.pgen.1009584
Light affects behavioral despair involving the clock gene Period 1
PLOS Genetics: published July 8, 2021 | https://doi.org/10.1371/journal.pgen.1009625
Quantitative mapping of mRNA 3’ ends in Pseudomonas aeruginosa reveals a pervasive role for premature 3’ end formation in response to azithromycin
PLOS Genetics: published July 12, 2021 | https://doi.org/10.1371/journal.pgen.1009634
Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans
PLOS Genetics: published July 8, 2021 | https://doi.org/10.1371/journal.pgen.1009635
A homozygous stop-gain variant in ARHGAP42 is associated with childhood interstitial lung disease, systemic hypertension, and immunological findings
PLOS Genetics: published July 7, 2021 | https://doi.org/10.1371/journal.pgen.1009639
Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1
PLOS Genetics: published July 2, 2021 | https://doi.org/10.1371/journal.pgen.1009640
Repeated evolution of circadian clock dysregulation in cavefish populations
PLOS Genetics: published July 12, 2021 | https://doi.org/10.1371/journal.pgen.1009642
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009647
Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009649
DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence
PLOS Genetics: published July 21, 2021 | https://doi.org/10.1371/journal.pgen.1009650
Functional and structural analyses of novel Smith-Kingsmore Syndrome-Associated MTOR variants reveal potential new mechanisms and predictors of pathogenicity
PLOS Genetics: published July 1, 2021 | https://doi.org/10.1371/journal.pgen.1009651
Powerful detection of polygenic selection and evidence of environmental adaptation in US beef cattle
PLOS Genetics: published July 22, 2021 | https://doi.org/10.1371/journal.pgen.1009652
Genomic analyses of new genes and their phenotypic effects reveal rapid evolution of essential functions in Drosophila development
PLOS Genetics: published July 9, 2021 | https://doi.org/10.1371/journal.pgen.1009654
Essential gene acquisition destabilizes plasmid inheritance
PLOS Genetics: published July 12, 2021 | https://doi.org/10.1371/journal.pgen.1009656
The selfish yeast plasmid utilizes the condensin complex and condensed chromatin for faithful partitioning
PLOS Genetics: published July 16, 2021 | https://doi.org/10.1371/journal.pgen.1009660
Genetic variation of BnaA3.NIP5;1 expressing in the lateral root cap contributes to boron deficiency tolerance in Brassica napus
PLOS Genetics: published July 1, 2021 | https://doi.org/10.1371/journal.pgen.1009661
Distinct spermiogenic phenotypes underlie sperm elimination in the Segregation Distorter meiotic drive system
PLOS Genetics: published July 6, 2021 | https://doi.org/10.1371/journal.pgen.1009662
Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex
PLOS Genetics: published July 12, 2021 | https://doi.org/10.1371/journal.pgen.1009663
Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR
PLOS Genetics: published July 2, 2021 | https://doi.org/10.1371/journal.pgen.1009664
A spectral theory for Wright’s inbreeding coefficients and related quantities
PLOS Genetics: published July 19, 2021 | https://doi.org/10.1371/journal.pgen.1009665
The RNA-binding protein Igf2bp3 is critical for embryonic and germline development in zebrafish
PLOS Genetics: published July 2, 2021 | https://doi.org/10.1371/journal.pgen.1009667
Fission yeast Rad8/HLTF facilitates Rad52-dependent chromosomal rearrangements through PCNA lysine 107 ubiquitination
PLOS Genetics: published July 22, 2021 | https://doi.org/10.1371/journal.pgen.1009671
The 3’tsRNAs are aminoacylated: Implications for their biogenesis
PLOS Genetics: published July 29, 2021 | https://doi.org/10.1371/journal.pgen.1009675
Negative linkage disequilibrium between amino acid changing variants reveals interference among deleterious mutations in the human genome
PLOS Genetics: published July 28, 2021 | https://doi.org/10.1371/journal.pgen.1009676
Identification of multiple odorant receptors essential for pyrethrum repellency in Drosophila melanogaster
PLOS Genetics: published July 8, 2021 | https://doi.org/10.1371/journal.pgen.1009677
CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression
PLOS Genetics: published July 14, 2021 | https://doi.org/10.1371/journal.pgen.1009678
Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease
PLOS Genetics: published July 29, 2021 | https://doi.org/10.1371/journal.pgen.1009679
Related Articles
Genome mapping coupled with CRISPR gene editing reveals a P450 gene confers avermectin resistance in the beet armyworm
PLOS Genetics: published July 12, 2021 | https://doi.org/10.1371/journal.pgen.1009680
Highly conserved and cis-acting lncRNAs produced from paralogous regions in the center of HOXA and HOXB clusters in the endoderm lineage
PLOS Genetics: published July 19, 2021 | https://doi.org/10.1371/journal.pgen.1009681
Diverse LXG toxin and antitoxin systems specifically mediate intraspecies competition in Bacillus subtilis biofilms
PLOS Genetics: published July 19, 2021 | https://doi.org/10.1371/journal.pgen.1009682
Sense-overlapping lncRNA as a decoy of translational repressor protein for dimorphic gene expression
PLOS Genetics: published July 28, 2021 | https://doi.org/10.1371/journal.pgen.1009683
An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
PLOS Genetics: published July 27, 2021 | https://doi.org/10.1371/journal.pgen.1009684
The blood flow-klf6a-tagln2 axis drives vessel pruning in zebrafish by regulating endothelial cell rearrangement and actin cytoskeleton dynamics
PLOS Genetics: published July 28, 2021 | https://doi.org/10.1371/journal.pgen.1009690
Induction of a chromatin boundary in vivo upon insertion of a TAD border
PLOS Genetics: published July 22, 2021 | https://doi.org/10.1371/journal.pgen.1009691
Oligopaint DNA FISH reveals telomere-based meiotic pairing dynamics in the silkworm, Bombyx mori
PLOS Genetics: published July 28, 2021 | https://doi.org/10.1371/journal.pgen.1009700
Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells
PLOS Genetics: published July 27, 2021 | https://doi.org/10.1371/journal.pgen.1009708
Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage
PLOS Genetics: published July 30, 2021 | https://doi.org/10.1371/journal.pgen.1009715
Opinion Pieces
Meiosis in Quarantine discussions lead to an action plan to increase diversity and inclusion within the genetics community
PLOS Genetics: published July 15, 2021 | https://doi.org/10.1371/journal.pgen.1009648
What connectomics can learn from genomics
PLOS Genetics: published July 16, 2021 | https://doi.org/10.1371/journal.pgen.1009692
Methods
A fast and robust Bayesian nonparametric method for prediction of complex traits using summary statistics
PLOS Genetics: published July 26, 2021 | https://doi.org/10.1371/journal.pgen.1009697