Dorsal view of a Drosophila larval brain stained for mitotic chromatin (magenta) and the neuronal marker Prospero (orange). Asymmetrically dividing stem cells expressing the Deadpan protein (cyan) are located within Prospero-positive regions in the central part of the brain and in the ventral ganglion. See Gallaud et al.
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Image Credit: Emmanuel Gallaud (image analysis) and Régis Giet (data acquisition).
Research Articles
Population genomics of the grapevine pathogen Eutypa lata reveals evidence for population expansion and intraspecific differences in secondary metabolite gene clusters
PLOS Genetics: published April 1, 2022 | https://doi.org/10.1371/journal.pgen.1010153
Heteroplasmic mitochondrial DNA variants in cardiovascular diseases
PLOS Genetics: published April 1, 2022 | https://doi.org/10.1371/journal.pgen.1010068
Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose
PLOS Genetics: published April 4, 2022 | https://doi.org/10.1371/journal.pgen.1009638
Reassembling a cannon in the DNA defense arsenal: Genetics of StySA, a BREX phage exclusion system in Salmonella lab strains
PLOS Genetics: published April 4, 2022 | https://doi.org/10.1371/journal.pgen.1009943
The chromatin remodeling protein CHD-1 and the EFL-1/DPL-1 transcription factor cooperatively down regulate CDK-2 to control SAS-6 levels and centriole number
PLOS Genetics: published April 4, 2022 | https://doi.org/10.1371/journal.pgen.1009799
The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent tumor formation
PLOS Genetics: published April 4, 2022 | https://doi.org/10.1371/journal.pgen.1010145
Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index
PLOS Genetics: published April 5, 2022 | https://doi.org/10.1371/journal.pgen.1010093
Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study
PLOS Genetics: published April 6, 2022 | https://doi.org/10.1371/journal.pgen.1010139
Aneuploidy influences the gene expression profiles in Saccharomyces pastorianus group I and II strains during fermentation
PLOS Genetics: published April 7, 2022 | https://doi.org/10.1371/journal.pgen.1010149
Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration
PLOS Genetics: published April 11, 2022 | https://doi.org/10.1371/journal.pgen.1010138
TTLL1 and TTLL4 polyglutamylases are required for the neurodegenerative phenotypes in pcd mice
PLOS Genetics: published April 11, 2022 | https://doi.org/10.1371/journal.pgen.1010144
A spatially aware likelihood test to detect sweeps from haplotype distributions
PLOS Genetics: published April 11, 2022 | https://doi.org/10.1371/journal.pgen.1010134
Filling gaps in bacterial catabolic pathways with computation and high-throughput genetics
PLOS Genetics: published April 13, 2022 | https://doi.org/10.1371/journal.pgen.1010156
The C-terminal domain of Hsp70 is responsible for paralog-specific regulation of ribonucleotide reductase
PLOS Genetics: published April 13, 2022 | https://doi.org/10.1371/journal.pgen.1010079
Genetic background influences survival of infections with Salmonella enterica serovar Typhimurium in the Collaborative Cross
PLOS Genetics: published April 13, 2022 | https://doi.org/10.1371/journal.pgen.1010075
Abnormal global alternative RNA splicing in COVID-19 patients
PLOS Genetics: published April 14, 2022 | https://doi.org/10.1371/journal.pgen.1010137
Ubiquitin ligase activity inhibits Cdk5 to control axon termination
PLOS Genetics: published April 14, 2022 | https://doi.org/10.1371/journal.pgen.1010152
A locus conferring tolerance to Theileria infection in African cattle
PLOS Genetics: published April 21, 2022 | https://doi.org/10.1371/journal.pgen.1010099
Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer
PLOS Genetics: published April 21, 2022 | https://doi.org/10.1371/journal.pgen.1010163
Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3ATR kinase is essential in the absence of Rqh1BLM helicase
PLOS Genetics: published April 22, 2022 | https://doi.org/10.1371/journal.pgen.1010165
MiR172-APETALA2-like genes integrate vernalization and plant age to control flowering time in wheat
PLOS Genetics: published April 25, 2022 | https://doi.org/10.1371/journal.pgen.1010157
Related Articles
Patagonian sheepdog: Genomic analyses trace the footprints of extinct UK herding dogs to South America
PLOS Genetics: published April 28, 2022 | https://doi.org/10.1371/journal.pgen.1010160
A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program
PLOS Genetics: published April 28, 2022 | https://doi.org/10.1371/journal.pgen.1010113
Differential modulation of C. elegans motor behavior by NALCN and two-pore domain potassium channels
PLOS Genetics: published April 28, 2022 | https://doi.org/10.1371/journal.pgen.1010126
Subnuclear localisation is associated with gene expression more than parental origin at the imprinted Dlk1-Dio3 locus
PLOS Genetics: published April 28, 2022 | https://doi.org/10.1371/journal.pgen.1010186
ENPP1 variants in patients with GACI and PXE expand the clinical and genetic heterogeneity of heritable disorders of ectopic calcification
PLOS Genetics: published April 28, 2022 | https://doi.org/10.1371/journal.pgen.1010192
Activation of class 1 integron integrase is promoted in the intestinal environment
PLOS Genetics: published April 28, 2022 | https://doi.org/10.1371/journal.pgen.1010177
The differential expression of PilY1 proteins by the HsfBA phosphorelay allows twitching motility in the absence of exopolysaccharides
PLOS Genetics: published April 29, 2022 | https://doi.org/10.1371/journal.pgen.1010188
Classification of non-coding variants with high pathogenic impact
PLOS Genetics: published April 29, 2022 | https://doi.org/10.1371/journal.pgen.1010191
Transcription of ncRNAs promotes repair of UV induced DNA lesions in Saccharomyces cerevisiae subtelomeres
PLOS Genetics: published April 29, 2022 | https://doi.org/10.1371/journal.pgen.1010167
α-Phenylalanyl tRNA synthetase competes with Notch signaling through its N-terminal domain
PLOS Genetics: published April 29, 2022 | https://doi.org/10.1371/journal.pgen.1010185
Correction
Correction: Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila
PLOS Genetics: published April 27, 2022 | https://doi.org/10.1371/journal.pgen.1010199
Related Articles
Methods
A modified TurboID approach identifies tissue-specific centriolar components in C. elegans
PLOS Genetics: published April 20, 2022 | https://doi.org/10.1371/journal.pgen.1010150
Related Articles
Efficient estimation of SNP heritability using Gaussian predictive process in large scale cohort studies
PLOS Genetics: published April 20, 2022 | https://doi.org/10.1371/journal.pgen.1010151