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Heidi Ruul

UURING ⟩ Laialt kasutatav ravim võib aidata vähendada Alzheimeri tõve riski

BBC Russian
Foto: Robert Kneschke / Shutterstock

Oxfordi ülikooli teadlased avastasid, et Viagra, tuntud ka kui sildenafiil, võib aidata ennetada Alzheimeri tõve, mis tekib veresoonte kitsenemisest ajus. Uuringus osales 75 inimest, kes olid saanud insuldi ja kellel oli probleeme aju väikestes veresoontes.

Topeltpimedas uuringus (ei patsient ega arst või uurija ei tea, millist ravi patsient saab) anti osalejatele kas Viagrat või platseebot (näiv ravim), ilma et nad teaksid, kumba nad saavad. 

Teadlased avastasid, et Viagra suurendas märkimisväärselt verevoolu aju väikestes veresoontes, mis on oluline, sest just väikeste veresoonte probleemid võivad viia vaskulaarse dementsuse tekkeni. Vaskulaarne dementsus on teist tüüpi dementsus pärast Alzheimeri tõbe ja see tekib, kui aju veresoontes on kahjustusi või verevool on piiratud, sageli pärast insulti.

Alastair Webb, Londoni Imperial College'i neuroloog selgitas ajakirjale Medical News Today: «Väikesoonte haigus on sügaval aju sees olevate väikeste veresoonte krooniline kahjustus, mille tulemusena muutuvad need kitsaks, ummistuvad ja lekkivad.»

Uuringus anti osalejatele ravimeid kolme nädala jooksul. MRI-skaneeringute ja muude testide abil kontrollisid teadlased, kas nende aju verevool on paranenud. Huvitaval kombel oli Viagrat kasutanud inimestel parem verevool oma väikestes ja keskmise suurusega veresoontes. See võib potentsiaalselt ennetada dementsust ja tõsiseid isheemilisi insulte.

Uuringu tulemused, mis avaldati mainekas ajakirjas Circulation Research, võivad olla keskse tähtsusega võitluses levinud neurodegeneratiivsete haiguste vastu. Tulemused on eriti paljutõotavad, kuna Viagra on juba laialdaselt kasutatav ravim ja selle kõrvaltoimeid ning riskirühmi on põhjalikult uuritud.

Allikad: ox.ac.uk, Economic Times

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