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1

USP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells.

Gao B, Qiao Y, Zhu S, Yang N, Zou SS, Liu YJ, Chen J. Gao B, et al. J Biol Chem. 2024 Jul;300(7):107463. doi: 10.1016/j.jbc.2024.107463. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876304 Free PMC article.

2

A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2.

Dederer V, Sanz Murillo M, Karasmanis EP, Hatch KS, Chatterjee D, Preuss F, Abdul Azeez KR, Nguyen LV, Galicia C, Dreier B, Plückthun A, Versees W, Mathea S, Leschziner AE, Reck-Peterson SL, Knapp S. Dederer V, et al. J Biol Chem. 2024 Jul;300(7):107469. doi: 10.1016/j.jbc.2024.107469. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876305 Free PMC article.

3

Smad7 palmitoylation by the S-acyltransferase zDHHC17 enhances its inhibitory effect on TGF-β/Smad signaling.

Voytyuk O, Ohata Y, Moustakas A, Ten Dijke P, Heldin CH. Voytyuk O, et al. J Biol Chem. 2024 Jul;300(7):107462. doi: 10.1016/j.jbc.2024.107462. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876303 Free PMC article.

4

Loss-of-function G6PD variant moderated high-fat diet-induced obesity, adipocyte hypertrophy, and fatty liver in male rats.

Matsumura S, Signoretti C, Fatehi S, Tumenbayar BI, D'Addario C, Nimmer E, Thomas C, Viswanathan T, Wolf A, Garcia V, Rocic P, Bae Y, Alam SS, Gupte SA. Matsumura S, et al. J Biol Chem. 2024 Jul;300(7):107460. doi: 10.1016/j.jbc.2024.107460. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876306 Free PMC article.

5

Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.

Yang Y, Xu L, Zhang S, Yao L, Ding Y, Li W, Chen X. Yang Y, et al. J Biol Chem. 2024 Jul;300(7):107468. doi: 10.1016/j.jbc.2024.107468. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876301 Free PMC article.

6

Discovery of a class of glycosaminoglycan lyases with ultrabroad substrate spectrum and their substrate structure preferences.

Wei L, Zou R, Du M, Zhang Q, Lu D, Xu Y, Xu X, Wang W, Zhang YZ, Li F. Wei L, et al. J Biol Chem. 2024 Jul;300(7):107466. doi: 10.1016/j.jbc.2024.107466. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876302 Free PMC article.

7

Dynamic stem-loop extension by Pol θ and templated insertion during DNA repair.

Carvajal-Maldonado D, Li Y, Returan M, Averill AM, Doublié S, Wood RD. Carvajal-Maldonado D, et al. J Biol Chem. 2024 Jul;300(7):107461. doi: 10.1016/j.jbc.2024.107461. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876299 Free PMC article.

8

Reconstitution of the alternative pathway of the complement system enables rapid delineation of the mechanism of action of novel inhibitors.

Goodrich AC, LeClair NP, Shillova N, Morton WD, Wittwer AJ, Loyet KM, Hannoush RN. Goodrich AC, et al. J Biol Chem. 2024 Jul;300(7):107467. doi: 10.1016/j.jbc.2024.107467. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876307 Free PMC article.

9

The proteostasis interactomes of trafficking-deficient variants of the voltage-gated potassium channel K_V11.1 associated with long QT syndrome.

Egly CL, Barny LA, Do T, McDonald EF, Knollmann BC, Plate L. Egly CL, et al. J Biol Chem. 2024 Jul;300(7):107465. doi: 10.1016/j.jbc.2024.107465. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876300 Free PMC article.

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