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Overview on the endoscopic treatment for obesity: A review

World J Gastroenterol. 2023 Oct 28;29(40):5526-5542. doi: 10.3748/wjg.v29.i40.5526.

Abstract

Obesity rates have increased, and so has the need for more specific treatments. This trend has raised interest in non-surgical weight loss techniques that are novel, safe, and straightforward. Thus, the present review describes the endoscopic bariatric treatment for obesity, its most recent supporting data, the questions it raises, and its future directions. Various endoscopic bariatric therapies for weight reduction, such as intragastric balloons (IGBs), aspiration therapy (AT), small bowel endoscopy, endoscopic sleeve gastroplasty, endoluminal procedures, malabsorption endoscopic procedures, and methods of regulating gastric emptying, were explored through literature sourced from different databases. IGBs, AT, and small bowel endoscopy have short-term effects with a possibility of weight regain. Minor adverse events have occurred; however, all procedures reduce weight. Vomiting and nausea are common side effects, although serious complications have also been observed.

Keywords: Gastric bypass; Intragastric balloons; Malabsorption; Overweight.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery* / adverse effects
  • Bariatric Surgery* / methods
  • Endoscopy, Gastrointestinal / adverse effects
  • Endoscopy, Gastrointestinal / methods
  • Gastric Emptying
  • Gastroplasty* / methods
  • Humans
  • Obesity / surgery
  • Obesity, Morbid* / surgery
  • Treatment Outcome
  • Weight Loss