Fuse mitochondria to win peer competition

Lang Wang; Yan Gu

doi:10.1016/j.neuron.2024.05.005

Fuse mitochondria to win peer competition

Neuron. 2024 Jun 19;112(12):1897-1899. doi: 10.1016/j.neuron.2024.05.005.

Authors

Lang Wang¹, Yan Gu²

Affiliations

¹ Department of Neurology of the First Affiliated Hospital, Interdisciplinary Institute of Neuroscience and Technology, Zhejiang University School of Medicine, Hangzhou 310027, China; School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou 310058, China.
² Center of Stem Cell and Regenerative Medicine, and Department of Neurology of the Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou 310058, China; MOE Frontier Science Center for Brain Science & Brain-Machine Integration, Zhejiang University, Hangzhou 310058, China. Electronic address: [email protected].

PMID: 38901399
DOI: 10.1016/j.neuron.2024.05.005

Abstract

In this issue of Neuron, Kochan et al.¹ report that enhanced mitochondrial fusion is essential for the heightened synaptic plasticity in adult-born neurons during the critical period, thus supporting their competition with neurons of similar age for survival.

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MeSH terms

Animals
Humans
Mitochondria* / metabolism
Mitochondrial Dynamics / physiology
Neuronal Plasticity* / physiology
Neurons* / physiology