Abstract
X-ray diffraction data from polyoma capsid crystals were phased by refinement of low-resolution starting models to obtain a self-consistent structural solution. The unexpected result that the hexavalent morphological unit is a pentamer shows that specificity of bonding is not conserved among the protein subunits in the icosahedrally symmetric capsid.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Capsid*
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Fourier Analysis
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Macromolecular Substances
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Models, Molecular
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Polyomavirus / ultrastructure*
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Protein Conformation
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Viral Proteins*
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X-Ray Diffraction
Substances
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Macromolecular Substances
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Viral Proteins