SIFT predicts whether an amino acid substitution affects protein function based on sequence homology and the physical properties of amino acids. SIFT can be applied to naturally occurring nonsynonymous polymorphisms and laboratory-induced missense mutations. |
Genome Tools | Single Protein Tools |
SNV / SNP prediction![]() |
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SIFT For Genomes (Online submission) (Beta) Predictions for some model organisms (e.g. human, mouse, worm, yeast). |
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dbSNP rsIDs (SIFT4G predictions) | ![]() |
INDEL Prediction 1. ![]() 2. Classify coding indels (Insertion/Deletions). Human build 37 and 38) |
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