The Cosby Show 

Long-running Perfect Strangers (1986) spin-off series centering on the Winslow family and their pesky next-door neighbor, ultra-nerd Steve Urkel.

The daily trials and tribulations of Tim Taylor, a TV show host raising three mischeivous boys with help from his loyal co-host, domineering wife, and genius neighbor.

Tony Micelli, a retired baseball player, becomes the housekeeper of Angela Bower, an advertising executive in New York. Together they raise their kids, Samantha Micelli and Jonathon Bower, with help from Mona Robinson, Angela's man-crazy mother.

A furry alien wiseguy comes to live with a terran family after crashing into their garage.

Chronicles liberal ex-hippies Steven and Elyse Keaton, their conservative son Alex, daughters Mallory and Jennifer, and later, youngest child Andrew.

The misadventures of a family with a home business father and a journalist mother.

The story of a working class family struggling with life's essential problems: Marriage, Children, Money and Parents in Law.

After the sudden death of his wife, a young father enlists the help of his brother-in-law and his childhood friend to help him raise his three young children.

The Cunningham family live through the 1950s with help and guidance from the lovable and almost superhuman greaser, Fonzie.

The misadventures of a wealthy Manhattan family who adopted the children of their late African American housekeeper from Harlem.

A sixteen-year-old high-school student finds out she's a witch.

Adolescent Cory Matthews grows up, and faces problems with friends, family, and school.