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Names | |
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IUPAC name
N-[(11R,20R,21R,25S,26S)-6-[(1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,21,25-tetrahydroxy-3,15-bis(1-hydroxyethyl)-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.09,13]heptacosan-18-yl]-4-(octyloxy)benzamide
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Other names | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
MeSH | Cilofungin |
PubChem CID
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UNII | |
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Properties | |
C49H71N7O17 | |
Molar mass | 1030.12474 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Cilofungin (INN)[1] is the first clinically applied member of the echinocandin family of antifungal drugs. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the synthesis of (1→3)-β-D-glucan).[2]
References
- ^ a b c "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 29" (PDF). World Health Organization.
- ^ Hudler, George (1998). Magical Mushrooms, Mischievous Molds. Princeton, New Jersey: Princeton University Press. pp. 112. ISBN 978-0-691-07016-2.
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