Svoboda | Graniru | BBC Russia | Golosameriki | Facebook

To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Epinastine

From Wikipedia, the free encyclopedia

Epinastine
Clinical data
Trade namesAlesion, Elestat, Purivist, Relestat
AHFS/Drugs.comMonograph
MedlinePlusa604011
Pregnancy
category
  • C
Routes of
administration		Eye drops
ATC code
Pharmacokinetic data
Protein binding64%
Elimination half-life12 hours
Identifiers
  • (RS)-3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine
CAS Number
ECHA InfoCard100.120.187 Edit this at Wikidata
Chemical and physical data
FormulaC16H15N3
Molar mass249.317 g·mol−1
3D model (JSmol)
  • N\4=C(\N3c1c(cccc1)Cc2c(cccc2)C3C/4)N
  • InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18) checkY
  • Key:WHWZLSFABNNENI-UHFFFAOYSA-N checkY
  (verify)

Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is produced by Allergan and marketed by Inspire in the United States.[1] It is highly selective for the H1 receptor and does not cross the blood-brain-barrier.[2]

It was patented in 1980 and came into medical use in 1994.[3]

References

  1. ^ Pradhan S, Abhishek K, Mah F (September 2009). "Epinastine: topical ophthalmic second generation antihistamine without significant systemic side effects". Expert Opinion on Drug Metabolism & Toxicology. 5 (9): 1135–1140. doi:10.1517/17425250903117284. PMID 19630694. S2CID 207490591.
  2. ^ Walther G, Daniel H, Bechtel WD, Brandt K (April 1990). "New tetracyclic guanidine derivatives with H1-antihistaminic properties. Chemistry of epinastine". Arzneimittel-Forschung. 40 (4): 440–446. PMID 1972625.
  3. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 549. ISBN 9783527607495.
Stub icon

This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.

This page was last edited on 20 December 2023, at 19:26
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy