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Heptabarb

From Wikipedia, the free encyclopedia

Heptabarb
Clinical data
Other namesG-475
Routes of
administration		Oral[1]
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability83%[1]
MetabolismHepatic
Elimination half-life6.1-11.2 hours[1]
ExcretionRenal[1]
Identifiers
  • 5-cyclohept-1-en-1-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
CAS Number
ECHA InfoCard100.007.371 Edit this at Wikidata
Chemical and physical data
FormulaC13H18N2O3
Molar mass250.298 g·mol−1
3D model (JSmol)
  • O=C1NC(=O)NC(=O)C1(/C2=C/CCCCC2)CC
  • InChI=1S/C13H18N2O3/c1-2-13(9-7-5-3-4-6-8-9)10(16)14-12(18)15-11(13)17/h7H,2-6,8H2,1H3,(H2,14,15,16,17,18) checkY
  • Key:PAZQYDJGLKSCSI-UHFFFAOYSA-N checkY
  (verify)

Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family.[2][3] It was used in Europe for the treatment of insomnia from the 1950s onwards, but has since been discontinued.[2][3]

See also

References

  1. ^ a b c d Breimer DD, de Boer AG (December 1975). "Pharmacokinetics and relative bioavailability of heptabarbital and heptabarbital sodium after oral administration to man". European Journal of Clinical Pharmacology. 9 (2–3): 169–78. doi:10.1007/bf00614014. PMID 9299. S2CID 32380531.
  2. ^ a b Ganellin CR, Triggle DJ, Macdonald F (1997). Dictionary of pharmacological agents. CRC Press. p. 1003. ISBN 978-0-412-46630-4. Retrieved 26 November 2011.
  3. ^ a b Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 513. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.
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This page was last edited on 4 February 2024, at 09:39
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