This is a list of antiviral drugs.
Antiviral drugs are different from antibiotics. Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as COVID-19. Antiviral drugs prescribed to treat COVID-19 are not approved or authorized to treat flu.[1]
List of Antiviral Drugs
Antiviral
Use
Manufacturer
Component
Type
Year approved
Abacavir
HIV
ViiV Healthcare
Nucleoside analogue reverse transcriptase inhibitor (NRTI)
1998
Acyclovir (Aciclovir)
Herpes Simplex , chickenpox ,[2] varicella zoster virus
guanosine analogue RTI
1981
Adefovir
Hepatitis B [3]
Gilead Sciences
RTI
2002 (FDA ), 2003 (EU )
Amantadine
Influenza
Influenza A virus M2 proton channel antagonist
Ampligen
Avian Influenza
Immunomodulatory double-stranded RNA
Amprenavir (Agenerase)
HIV
Protease inhibitor (PI)
Umifenovir (Arbidol)
Influenza
Hemagglutinin inhibitor
Atazanavir
HIV
PI
Atripla (Efavirenz /emtricitabine /tenofovir )
HIV
Efavirenz: Non-nucleoside RTI (NNRTI)
Emtricitabine: NRTI
Tenofovir disoproxil: NRTI
Baloxavir marboxil (Xofluza)[4]
Influenza A/B
Cap snatching endonuclease inhibitor
2018
Biktarvy (Bictegravir /emtricitabine /tenofovir alafenamide )
HIV
Bictegravir: INSTI
Emtricitabine: NRTI
Tenofovir alafenamide: NRTI
Boceprevir
Hepatitis C genotype 1[5]
Schering-Plough, then Merck Group
Protease inhibitor
FDA approved 2011
Withdrawn 2015
Bulevirtide
Hepatitis D /B
Sodium/bile acid cotransporter inactivator
Cidofovir
AIDS
Viral DNA Polymerase inhibitor
Cobicistat (Tybost)[6]
HIV
human CYP3A protein inhibitor
Combivir (Lamivudine /Zidovudine )
HIV
Daclatasvir (Daklinza)
Hepatitis C
NS5A inhibitor
Darunavir
HIV
antiretroviral
HIV PI
Delavirdine
HIV
antiretroviral
NNRTI
Descovy (Emtricitabine/tenofovir alafenamide)
Hepatitis B
Emtricitabine: NRTI
Tenofovir alafenamide: NRTI
Didanosine
HIV
Adenosine analogue RTI
Docosanol
Herpes Simplex
Entry inhibitor
Dolutegravir
HIV
Integrase inhibitor
Doravirine (Pifeltro)[7]
HIV
NNRTI
Edoxudine
Herpes Simplex
Thymidine analogue inhibitor
Efavirenz
HIV
Mylan
NNRTI
1998
Elvitegravir
HIV
Gilead Sciences
Integrase inhibitor
Emtricitabine
HIV
Gilead Sciences
NRTI
2003
Enfuvirtide
HIV
Entry inhibitor
2003
Ensitrelvir
COVID-19
Shionogi
3C-like protease inhibitor
Entecavir
HIV
NRTI
2005
Etravirine (Intelence)[8]
HIV
NNRTI
2008
Famciclovir
Herpes Zoster
Guanosine analogue
1994
Fomivirsen
AIDS
Anti-sense oligonucleotide
Anti-sense
FDA-licensed in 1998
Withdrawn in EU (2002), US (2006)
Fosamprenavir
HIV
ViiV Healthcare
Amprenavir pro-drug
2003 (FDA), 2004 (EMA )
Foscarnet
Herpes
Pyrophosphate analogue DNA polymerase inhibitor
1991
Ganciclovir (Cytovene)[9]
Cytomegalovirus (CMV)[10]
Competitive nucleoside analogue dGTP inhibitor
1988
Ibacitabine
Herpes labialis
Ibalizumab (Trogarzo)[11]
HIV
Entry inhibitor
2018
Idoxuridine
Herpes
dU analogue inhibitor
1962
Imiquimod
Genital wart , Basal cell carcinoma , Actinic keratosis
Opioid growth factor receptor (OGFr) agonist
1997
Inosine pranobex
Herpes Simplex
Thymus hormone immunostimulant
Indinavir
HIV
PI
1996
Lamivudine
HIV
cytidine analogue RTI
Letermovir (Prevymis)[12]
Cytomegalovirus (CMV)
Lopinavir
HIV
Loviride
HIV
Maraviroc
HIV
entry inhibitor
Methisazone
Smallpox
Molnupiravir
COVID-19
viral RNA polymerase inhibitor
Moroxydine
Influenza
Nelfinavir
HIV
Nirmatrelvir/ritonavir (Paxlovid)
COVID-19
Pfizer
3C-like protease inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir)
Nevirapine
HIV
non-nucleoside reverse transcriptase inhibitor
Nitazoxanide
Broad-spectrum antiviral
thiazolide
Norvir
HIV
Oseltamivir (Tamiflu)[13]
Influenza
neuraminidase inhibitor
Peramivir (Rapivab)[14]
Influenza
Penciclovir
Herpes
Pleconaril
Picornavirus
Schering-Plough
Podophyllotoxin
Genital wart
Raltegravir
HIV
Integrase inhibitor
Remdesivir
COVID-19
viral RNA polymerase inhibitor
Ribavirin
Hepatitis C[15]
nucleoside analogue reverse transcriptase inhibitor
Rilpivirine (Edurant)[16]
HIV
Rimantadine
Influenza A
M2 proton channel antagonist
Ritonavir
HIV
HIV-1 protease inhibitor
Saquinavir
HIV
Simeprevir (Olysio)
Hepatitis C
Sofosbuvir
Hepatitis C[17]
nucleoside analogue reverse transcriptase inhibitor
Stavudine
HIV
Taribavirin (Viramidine)
Hepatitis Syndromes in which Ribavirin is active[18]
Telaprevir
Hepatitis C
Telbivudine (Tyzeka)
Hepatitis B
Tenofovir alafenamide
Hepatitis B
Tenofovir disoproxil
Hepatitis B, HIV[19]
Tipranavir
HIV
Trifluridine
Eyes related Herpes
Trizivir
HIV
Tromantadine
Herpes Simplex
Truvada
HIV
Umifenovir
Influenza
Valaciclovir (Valtrex)[20]
Herpes Simplex/Zoster
Valganciclovir (Valcyte)[21]
Cytomegalovirus (CMV)
Vicriviroc
HIV-1
Schering-Plough
pyrimidine CCR5 entry inhibitor
Vidarabine
Herpes Simplex, Varicella Zoster
Zalcitabine
HIV
Zanamivir (Relenza)[22]
Influenza A, Influenza B
Zidovudine
HIV[23]
Antiretroviral
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References
^ "What You Should Know about Flu Antiviral Drugs" . 15 December 2022.
^ "Acyclovir" . The American Society of Health-System Pharmacists. Archived from the original on 2015-01-05. Retrieved Jan 1, 2015 .
^ Marcellin P, Chang TT, Lim SG, Tong MJ, Sievert W, Shiffman ML, et al. (February 2003). "Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B" . The New England Journal of Medicine . 348 (9): 808–16. doi :10.1056/NEJMoa020681 . PMID 12606735 .
^ "Xofluza- baloxavir marboxil tablet, film coated" . DailyMed . 28 October 2019. Retrieved 21 September 2020 .
^ Degertekin B, Lok AS (May 2008). "Update on viral hepatitis: 2007". Curr. Opin. Gastroenterol. 24 (3): 306–11. doi:10.1097/MOG.0b013e3282f70285. PMID 18408458 . S2CID 43762307
^ "Tybost- cobicistat tablet, film coated" . DailyMed . 27 August 2020. Retrieved 21 September 2020 .
^ "Pifeltro- doravirine tablet, film coated" . DailyMed . 10 October 2019. Retrieved 21 September 2020 .
^ "Intelence- etravirine tablet" . DailyMed . 9 June 2020. Retrieved 21 September 2020 .
^ "Cytovene IV- ganciclovir sodium injection, powder, lyophilized, for solution" . DailyMed . 19 June 2020. Retrieved 21 September 2020 .
^ Rossi S, editor. Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook; 2006. ISBN 0-9757919-2-3
^ "Trogarzo- ibalizumab injection, solution" . DailyMed . 8 April 2020. Retrieved 21 September 2020 .
^ "Prevymis- letermovir tablet, film coated PREVYMIS- letermovir injection, solution" . DailyMed . 23 March 2020. Retrieved 21 September 2020 .
^ "Tamiflu- oseltamivir phosphate capsule TAMIFLU- oseltamivir phosphate powder, for suspension" . DailyMed . Retrieved 21 September 2020 .
^ "Rapivab- peramivir solution" . DailyMed . 3 August 2020. Retrieved 21 September 2020 .
^ "Rebetol, Ribasphere (ribavirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 28 February 2014. Retrieved 23 February 2014.
^ "Edurant- rilpivirine hydrochloride tablet, film coated" . DailyMed . 8 June 2020. Retrieved 21 September 2020 .
^ Berden FA, Kievit W, Baak LC, Bakker CM, Beuers U, Boucher CA, Brouwer JT, Burger DM, van Erpecum KJ, van Hoek B, Hoepelman AI, Honkoop P, Kerbert-Dreteler MJ, de Knegt RJ, Koek GH, van Nieuwkerk CM, van Soest H, Tan AC, Vrolijk JM, Drenth JP (October 2014). "Dutch guidance for the treatment of chronic hepatitis C virus infection in a new therapeutic era". The Netherlands Journal of Medicine . 72 (8): 388–400. PMID 25387551 .
^ Gish RG (January 2006). "Treating HCV with ribavirin analogues and ribavirin-like molecules". The Journal of Antimicrobial Chemotherapy. 57 (1): 8–13. doi:10.1093/jac/dki405. PMID 16293677
^ "Tenofovir Disoproxil Fumarate". The American Society of Health-System Pharmacists. Archived from the original on 30 November 2016. Retrieved 29 November 2016.
^ "Valtrex- valacyclovir hydrochloride tablet, film coated" . DailyMed . 10 December 2019. Retrieved 21 September 2020 .
^ "Valcyte- valganciclovir tablet, film coated VALCYTE- valganciclovir hydrochloride powder, for solution" . DailyMed . 9 August 2018. Retrieved 3 September 2022 .
^ "Relenza- zanamivir powder" . DailyMed . 21 June 2018. Retrieved 21 September 2020 .
^ "Zidovudine" . PubChem Public Chemical Database . NCBI. Archived from the original on October 25, 2012. Retrieved April 10, 2011 .
This page was last edited on 4 May 2024, at 14:31