Mio is a feminine Japanese given name, as well as a unisex Swedish given name. Notable people with the name include:
- MIQ (vocalist) (born 1955), female Japanese pop and anime theme song vocal artist, who first used MIO as her name
- Mio Imada (今田 美桜, born 1997), Japanese model and actress
- Mio Isayama (諫山 実生, born 1980), Japanese singer
- Mio Kudo (工藤 美桜, born 1999), Japanese actress
- Mio Matsumura (松村 未央, born 1986), Japanese female announcer
- Mio Momono (桃野 美桜, born 1998), Japanese professional wrestler
- Mio Narita (成田 実生, born 2006), Japanese competitive swimmer
- Mio Otani (大谷 未央, born 1979), Japanese football player
- Mio Ootani (大谷 澪, born 1992), Japanese gravure idol
- Mio Satō (佐藤 澪, born 1993), Japanese actress, model and tarento
- Mio Shinozaki (篠崎 澪, born 1991), Japanese professional basketball
- Mio Shirai (紫雷 美央, born 1988), Japanese professional wrestler
- Mio Sugita (杉田 水脈, born 1967), Japanese politician
- Mio Takaki (高樹 澪, born 1959), Japanese actress and singer
- Mio Tomonaga (朝長 美桜, born 1998), Japanese idol, a member of HKT48
- Mio Tsumura (津村 澪, born 1995), Japanese kickboxer
- Mio Yamanaka (山中 美緒, born 1995), Japanese female rugby union player
- Mio Yoshizumi, former member of the Japanese girl group Kamen Rider Girls
- Mio Yūki (優希 美青, born 1999), Japanese actress, model and tarento
Fictional characters
- Mio, a character in the book Mio, My Son, by Astrid Lindgren
- Mio, a character in the tokusatsu series Ressha Sentai ToQger
- Mio, a character in the video game Grandia
- Mio, a character in the video game Xenoblade Chronicles 3
- Mio Akiyama, a character in the manga and anime series K-On!
- Mio Amakura, a character in the video game series Fatal Frame
- Mio Chibana, a main character in the manga series L'étranger
- Mio Honda, a character in the media franchise The Idolmaster
- Mio Kusakai, a character in the manga and anime series Keijo
- Mio Minato, a character in the anime series Aikatsu Friends!
- Mio Naganohara, a main character from the anime and manga series Nichijou
- Mio Naruse, a character in the light novel series The Testament of Sister New Devil
- Mio Ookami, a Japanese member of Hololive
- Mio Sakamoto, a character in the media franchise Strike Witches
- Mio Suzuki, a character in the tokusatsu series Kamen Rider Kiva, also known as the Pearlshell Fangire/Queen
- Mio Takamiya, a character in the light novel series Date A Live
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