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Ozolinone

From Wikipedia, the free encyclopedia

Ozolinone
Skeletal formula of ozolinone
Space-filling model of oxolinone
Clinical data
Routes of
administration		Oral
ATC code
  • None
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • (2Z)-2-(3-methyl-4-oxo-5-piperidin-1-yl-1,3-thiazolidin-2-ylidene)acetic acid
CAS Number
Chemical and physical data
FormulaC11H16N2O3S
Molar mass256.32 g·mol−1
3D model (JSmol)
  • O=C(O)/C=C1/N(C)C(=O)C(S1)N2CCCCC2

Ozolinone is a loop diuretic which was never marketed.[1][2][3]

It is an active metabolite of etozoline.[2]

See also

References

  1. ^ Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8.
  2. ^ a b Greven J, Heidenreich O (October 1978). "Effects of ozolinone, a diuretic active metabolite of etozoline, on renal function. I. Clearance studies in dogs". Naunyn-Schmiedeberg's Archives of Pharmacology. 304 (3): 283–7. doi:10.1007/bf00507970. PMID 714186. S2CID 20878253.
  3. ^ Greven J, Beckers M, Defrain W, Meywald K, Heidenreich O (March 1980). "Studies with the optically active isomers of the new diuretic drug ozolinone. II. Inhibition by d-ozolinone of furosemide-induced diuresis". Pflügers Archiv: European Journal of Physiology. 384 (1): 61–4. doi:10.1007/bf00589515. PMID 7189867. S2CID 13461213.


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