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SLC39A11

Identifiers

SLC39A11, C17orf26, ZIP11, solute carrier family 39 member 11, ZIP-11

External IDs

OMIM: 616508 MGI: 1917056 HomoloGene: 12331 GeneCards: SLC39A11

Gene location (Human)

Chr.	Chromosome 17 (human)^[1]

Band	17q24.3-q25.1	Start	72,645,949 bp^[1]
Band	17q24.3-q25.1	End	73,092,712 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 11 (mouse)^[2]

Band	11\|11 E2	Start	113,135,679 bp^[2]
Band	11\|11 E2	End	113,540,905 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

bone marrow cells

pancreatic ductal cell

monocyte

rectum

liver

right lobe of liver

duodenum

islet of Langerhans

corpus callosum

left lobe of thyroid gland

Top expressed in

epithelium of stomach

pyloric antrum

parotid gland

mucous cell of stomach

submandibular gland

lacrimal gland

crypt of lieberkuhn of small intestine

duodenum

left colon

molar

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	metal ion transmembrane transporter activity zinc ion transmembrane transporter activity
Cellular component	cytoplasm integral component of membrane plasma membrane Golgi apparatus nucleus membrane fungal-type vacuole membrane
Biological process	metal ion transport zinc ion transport ion transport transmembrane transport zinc ion transmembrane transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


201266


69806

Ensembl


ENSG00000133195 ENSG00000282291


ENSMUSG00000041654

UniProt


Q8N1S5


Q8BWY7

RefSeq (mRNA)


NM_001159770 NM_139177 NM_001352691 NM_001352692 NM_001352693

NM_001166503 NM_027216 NM_001362937 NM_001362938 NM_001362939
NM_001362940 NM_001362941 NM_001362942 NM_001362943 NM_001362944

RefSeq (protein)


NP_001153242 NP_631916 NP_001339620 NP_001339621 NP_001339622

NP_001159975 NP_081492 NP_001349866 NP_001349867 NP_001349868
NP_001349869 NP_001349870 NP_001349871 NP_001349872 NP_001349873

Location (UCSC)

Chr 17: 72.65 – 73.09 Mb

Chr 11: 113.14 – 113.54 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Solute carrier family 39 member 11 is a protein that in humans is encoded by the SLC39A11 gene. ^[5]

References

^ ^a ^b ^c ENSG00000282291 GRCh38: Ensembl release 89: ENSG00000133195, ENSG00000282291 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041654 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Solute carrier family 39 member 11". Retrieved 2017-10-11.

Bagheri-Fam S, Ferraz C, Demaille J, Scherer G, Pfeifer D (2001). "Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions". Genomics. 78 (1–2): 73–82. doi:10.1006/geno.2001.6648. PMID 11707075.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
Wu L, Chaffee KG, Parker AS, Sicotte H, Petersen GM (2015). "Zinc transporter genes and urological cancers: integrated analysis suggests a role for ZIP11 in bladder cancer". Tumour Biol. 36 (10): 7431–7. doi:10.1007/s13277-015-3459-2. PMC 4607554. PMID 25900876.

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This page was last edited on 4 March 2023, at 11:13

SLC39A11

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References

Further reading