 | |
| Clinical data | |
|---|---|
| Trade names | Simparica |
| Other names | PF-6450567 |
| ATCvet code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| |
| CAS Number | |
| ECHA InfoCard | 100.234.000 |
| Chemical and physical data | |
| Formula | C23H18Cl2F4N2O5S |
| Molar mass | 581.36 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs.[5][6] It is also used off-label to control sarcoptic mange and demodectic mange.[6]
Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel.[7][8] It is used for prevention of heartworm disease caused by Dirofilaria immitis; treat and prevent flea infestations; treat and control tick infestations with the lone star tick, Gulf Coast tick, American dog tick, black-legged tick, and brown dog tick; and treat and control roundworm and adult hookworm infections.[9]
Sarolaner is also an ingredient in feline combination antiparasitic Revolution Plus (or Stronghold Plus[10]), which contains sarolaner and selamectin and is used for prevention of sarcoptic mange, feline hookworms, feline roundworms, ear mites, and heartworms, as well as treating and preventing fleas and ticks.[11]
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Sarolaner, ¿la mejor isoxazolina?
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Antipulgas Simparic 40 mg para cães 10 a 20 kg funciona? Vale a Pena Comprá-lo?
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References
- ^ "Approved in 2020: Drugs for human use". Health Canada. 26 July 2021. Retrieved 27 March 2024.
- ^ "Simparica". U.S. Food and Drug Administration (FDA). Retrieved 12 December 2022.
- ^ "Simparica EPAR". European Medicines Agency. 18 December 2015. Retrieved 13 June 2024.
- ^ "MiPet Easecto EPAR". European Medicines Agency. 23 February 2018. Retrieved 13 June 2024.
- ^ McTier TL, Chubb N, Curtis MP, Hedges L, Inskeep GA, Knauer CS, et al. (May 2016). "Discovery of sarolaner: A novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs" (PDF). Veterinary Parasitology. 222: 3–11. doi:10.1016/j.vetpar.2016.02.019. PMID 26961590.
- ^ a b Gollakner R. "Sarolaner". vcahospitals.com. VCA Hospitals. Retrieved 26 June 2021.
- ^ "Simparica Trio". U.S. Food and Drug Administration (FDA). Retrieved 12 December 2022.
- ^ "Simparica Trio EPAR". European Medicines Agency. 14 October 2019. Retrieved 15 June 2024.
- ^ "FDA Approves Simparica Trio, a Combination Drug for Heartworm and Other Parasites". U.S. Food and Drug Administration (FDA). 2 March 2020. Retrieved 26 June 2021.
- ^ "Stronghold Plus". European Medicines Agency. Retrieved 12 December 2022.
- ^ "Revolution Plus". U.S. Food and Drug Administration (FDA). Retrieved 12 December 2022.
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This page was last edited on 15 June 2024, at 22:06