Silicone granuloma | |
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Snowball like hyperechogenic axillary lymph nodes in a woman with silicone implants removed due to complications | |
Specialty | Dermatology |
Silicone granulomas are a skin condition that occur as a reaction to liquid silicones, and are characterized by the formation of nodules.[1]: 46
Formation of a granuloma is a common tissue response to a range of foreign bodies. Silicone can be directly injected into tissue as part of a cosmetic procedure or it can leak from silicone implants. The formation and consequences of silicon-induced granulomas is not well described or understood. The extent of damage that they cause is controversial.[2]
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Silicone granulomas from cosmetic filer injection For medical education- NSFE.
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Correcting Silicon Injections Medical Course
Transcription
Localization
- Lymph node: Granulomatous lymphadenitis[3][4]
- Skin: Granulomatous dermatitis[5][6][7]
- Penis[8]
- Breast: Granulomatous mastitis[9][10]
- Face: Granulomatous facial reaction [11]
Effects
Silicone-induced granuloma can be associated with fever,[12] calcitriol-mediated hypercalcemia,[13] reactive amyloidosis.[14][15][16]
Treatment
Treatment of silicone granulomas and removal of unwanted silicone have historically been very challenging. Anti-inflammatory agents (e.g., oral corticosteroids, allopurinol, colchicine, isotretinoin, cyclosporine, imiquimod, antibiotics) may help treat the granulomatous inflammation,[17] but do not address or remove the underlying source silicone material. Surgical excision allows for removal of the underlying source of inflammation, but is often deferred due to associated scarring.[18]
More recently, a case of successful removal of injected silicone using microcoring technology was reported, providing a potential scar-less option for its removal.[18]
Gallery
See also
References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
- ^ . The Journal of Clinical and Aesthetic Dermatology. 5 (7): 44–7. PMC 3396457. PMID 22798975.
- ^ . Journal of Clinical Pathology. 53 (7): 549–51. doi:10.1136/jcp.53.7.549. PMC 1731232. PMID 10961180.
- ^ Acta Otorrinolaringológica Española. 64 (3): 217–22. doi:10.1016/j.otorri.2012.12.003. PMID 23499209.
- ^ . Dermatology Online Journal. 19 (12): 20708. doi:10.5070/D31912020708. PMID 24364999.
- ^ . Case Reports in Dermatological Medicine. 2011: 1–3. doi:10.1155/2011/129138. PMC 3505939. PMID 23198167.
- ^ Dermatology Online Journal. 14 (7): 20. doi:10.5070/D37JX780XV. PMID 18718204.
- ^ Inn, F. X.; Imran, F. H.; Ali, M. F.; Ih, R; z, Z (2012). "Penile augmentation with resultant foreign material granuloma and sequalae". The Malaysian Journal of Medical Sciences. 19 (4): 81–3. PMC 3629684. PMID 23613653.
- ^ . Case Reports in Dermatological Medicine. 2011: 1–3. doi:10.1155/2011/129138. PMC 3505939. PMID 23198167.
- ^ . British Medical Journal. 3 (5609): 19–22. doi:10.1136/bmj.3.5609.8-a. PMC 1989508. PMID 5690841.
- ^ Poveda, R; Bagán, J. V.; Murillo, J; Jiménez, Y (2006). "Granulomatous facial reaction to injected cosmetic fillers--a presentation of five cases". Medicina Oral, Patologia Oral y Cirugia Bucal. 11 (1): E1–5. PMID 16388285.
- ^ The Israel Medical Association Journal. 9 (2): 121–2. PMID 17348488.
- ^ . Case Reports in Medicine. 2013: 1–3. doi:10.1155/2013/807292. PMC 3864076. PMID 24363673.
- ^ . BMJ Case Reports. 2012: bcr2012006803. doi:10.1136/bcr-2012-006803. PMC 4543521. PMID 23035166.
- ^ Aesthetic Plastic Surgery. 26 (5): 383–7. doi:10.1007/s00266-002-2022-x. PMID 12432480. S2CID 6865930.
- ^ Radiologic Clinics of North America. 34 (2): 375–94, xi. doi:10.1016/S0033-8389(22)00474-2. PMID 8633122. S2CID 251523786.
- ^ . Dermatologic Surgery. 45 (3): 489–492. doi:10.1097/DSS.0000000000001574. ISSN 1076-0512.
- ^ a b . Dermatologic Surgery. doi:10.1097/DSS.0000000000004068. ISSN 1076-0512.
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