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Chemical and physical data | |
Formula | C29H25NO3 |
Molar mass | 435.523 g·mol−1 |
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YCT529 is a drug which acts as a potent and selective antagonist of the Vitamin A receptor retinoic acid receptor alpha (RAR-α). In studies on mice it produced a 99% reduction in sperm production, and it has proceeded to early stage human clinical trials as a potential male contraceptive.[1]
The Vitamin A signalling system plays a number of important roles in bodily systems, such as the Immune system “It seems to me inherently unlikely that a compound with such activity would be free of side effects,” says Richard Sharpe, of the University of Edinburgh.[2]
See also
References
- ^ "A non-hormonal pill could soon expand men's birth control options". ACS News. 23 March 2022.
- ^ Wilkins A (23 March 2022). "Male contraceptive pill is safe and effective in tests in mice". New Scientist.
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