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ASCL2

De Wikipedia, la enciclopedia libre

Achaete-scute complex homolog 2 (Drosophila)
Estructuras disponibles
PDB Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos ASCL2 (HGNC: 739) ASH2; HASH2; MASH2
Identificadores
externos
Locus Cr. 11 p15.5
Ortólogos
Especies
Humano Ratón
Entrez
430
UniProt
Q99929   n/a
RefSeq
(ARNm)
NP_005161 n/a
[editar datos en Wikidata]

ASCL2 (del inglés "Achaete-scute complex homolog 2 (Drosophila)") es un gen humano susceptible de generar impronta genética.[1]​

Este gen es miembro de la familia de factores de transcripción con un dominio hélice-bucle-hélice. Activa la transcripción mediante su unión a las E-box (5'-CANNTG-3'). La dimerización con otras proteínas de la misma familia es requerida para una eficiente unión al ADN. Esta proteína también está implicada en la determinación de los precursores neuronales en el sistema nervioso periférico y en el sistema nervioso central.[1]​

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Transcription

Interacciones

La proteína ASCL2 ha demostrado ser capaz de interaccionar con:

Referencias

  1. ↑ a b «Entrez Gene: ASCL2 achaete-scute complex homolog 2 (Drosophila)». 
  2. ↑ a b Goo, Young-Hwa; Sohn Young Chang, Kim Dae-Hwan, Kim Seung-Whan, Kang Min-Jung, Jung Dong-Ju, Kwak Eunyee, Barlev Nickolai A, Berger Shelley L, Chow Vincent T, Roeder Robert G, Azorsa David O, Meltzer Paul S, Suh Pan-Gil, Song Eun Joo, Lee Kong-Joo, Lee Young Chul, Lee Jae Woon (Jan. de 2003). «Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins». Mol. Cell. Biol. (United States) 23 (1): 140-9. ISSN 0270-7306. PMID 12482968. 
Esta página se editó por última vez el 4 sep 2019 a las 13:58.
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