Gtp Binding Proteins
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Recent papers in Gtp Binding Proteins
Chronic opioid receptor (OR) activation by morphine causes distinct cellular adaptations responsible for the development of tolerance. The present study examines the effect of chronic morphine exposure on the ability of high-efficacy... more
To determine celiac disease (CD) prevalence and associated manifestations or risk factors in healthy adult Emiratis. It is a cross-sectional prospective study, recruiting 1197 (573 women and 624 men) healthy Emiratis between September... more
We identified nine naturally-occurring human single nucleotide polymorphisms (SNPs) in the alpha(1a)-adrenoceptor (alpha(1a)AR) coding region, seven of which result in amino acid change. Utilizing rat-1 fibroblasts stably expressing wild... more
Progression through mitosis occurs because cyclin B/Cdc2 activation induces the anaphase promoting complex (APC) to cause cyclin B destruction and mitotic exit. To ensure that cyclin B/Cdc2 does not prematurely activate the APC in early... more
Although the Rap1A protein resembles the oncogenic Ras proteins both structurally and biochemically, Rap1A exhibits no oncogenic properties. Rather, overexpression of Rap1A can reverse Ras-induced transformation of NIH 3T3 cells. Because... more
Lipid droplets (LDs) are the major fat storage organelles in eukaryotic cells, but how their size is regulated is unknown. Using genetic screens in C. elegans for LD morphology defects in intestinal cells, we found that mutations in... more
Purpose: The study aimed to evaluate the (i) regulatory role of G i-like protein during the acrosome reaction (AR) of normal sperm donors and (ii) the role of intact acrosomes during sperm–zona binding. Methods: The acrosomal exocytosis... more