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Recalibrate concepts of epigenetic aging clocks in human health

Ze Zhang, Brock C. Christensen, Lucas A. Salas,

https://doi.org/10.18632/aging.206027

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Physical fitness and lifestyles associated with biological aging

Takuji Kawamura, Radak Zsolt, Mitsuru Higuchi, Kumpei Tanisawa,

https://doi.org/10.18632/aging.206031

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Lipid accumulation drives cellular senescence in dopaminergic neurons

Taylor Russo, Markus Riessland,

https://doi.org/10.18632/aging.206030

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Trioxidized cysteine and aging: a molecular binomial that extends far beyond classical proteinopathic paradigms

José Antonio Sánchez Milán, María Mulet, Aida Serra, Xavier Gallart-Palau,

https://doi.org/10.18632/aging.206036

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mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease

Karl Berner, Naci Oz, Alaattin Kaya, Animesh Acharjee, Jon Berner,

https://doi.org/10.18632/aging.206033

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CCNA2 and KIF23 are molecular targets for the prognosis of adenoid cystic carcinoma

Yongbin Di, Haolei Zhang, Bohao Zhang, Tianke Li, Dan Li,

https://doi.org/10.18632/aging.205703

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SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma

Guojing Chai, Yingbo Nan, Haili Zhao, Qingchuan Hu,

https://doi.org/10.18632/aging.205799

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RGC32 promotes the progression of ccRCC by activating the NF-κB/SHP2/EGFR signaling pathway

Jing Zhang, Yindi Sun, Kai Tang, Huirong Xu, Junjuan Xiao, Yan Li,

https://doi.org/10.18632/aging.205890

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Precision prognostication in breast cancer: unveiling a long non-coding RNA-based model linked to disulfidptosis for tailored immunotherapeutic strategies

Chenglu Jiang, Shengke Zhang, Lai Jiang, Zipei Chen, Haiqing Chen, Jinbang Huang, Xuancheng Zhou, Jingyi Tang, Xinrui Gao, Hao Chi, Guanhu Yang, Shangke Huang,

https://doi.org/10.18632/aging.205946

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Prognostic relevance and validation of ARPC1A in the progression of low-grade glioma

Jingyuan Dai, Jiahui Gao, Hongchao Dong,

https://doi.org/10.18632/aging.205952

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Identifying novel circadian rhythm biomarkers for diagnosis and prognosis of melanoma by an integrated bioinformatics and machine learning approach

Yi Xu, Churuo Zeng, Jie Bin, Hua Tang, Wei Li,

https://doi.org/10.18632/aging.205961

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Comprehensive analysis of LMNB2 in pan-cancer and identification of its biological role in sarcoma

Yonghui Guo, Min Zhang, Yingrui Luo, Yingshi Li, Yanxia Xu, Nisha Wang,

https://doi.org/10.18632/aging.205962

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Identification of immunotherapy-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognostic signature in gastric carcinoma

Jianxin Li, Ting Han, Jieyi Yang, Xin Wang, Yinchun Wang, Rui Yang, Qingqiang Yang,

https://doi.org/10.18632/aging.205968

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Exploring the mechanism by which Angelica sinensis improves haematopoietic function in aplastic anaemia

Zetao Chen, Li Cheng, Jing Zhang, Xing Cui,

https://doi.org/10.18632/aging.205971

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Cyclin L1 participates in Adriamycin resistance and progression of osteosarcoma via PI3K/AKT-mTOR pathway

Yanbin Zhang, Tao Zhang, Long Chen, Zijun Guo, Xiaobing Jiang,

https://doi.org/10.18632/aging.205972

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Pan-cancer analysis of T-cell proliferation regulatory genes as potential immunotherapeutic targets

Ruqiong Wei, Shihui Xiao, Shijian Zhao, Wenliang Guo, Ying Liu, Marìa del Mar Requena Mullor, Raquel Alarcòn Rodrìguez, Qingjun Wei, Yinteng Wu,

https://doi.org/10.18632/aging.205977

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Integrative pan-cancer analysis reveals the prognostic and immunotherapeutic value of ALKBH7 in HNSC

Tianyu Wang, Bojian Lin, Boyu Cai, Zhiwen Cao, Caiquan Liang, Shunyu Wu, Enhong Xu, Li Li, Hu Peng, Huanhai Liu,

https://doi.org/10.18632/aging.205981

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Interference with ANXA8 inhibits the malignant progression of ovarian cancer by suppressing the activation of the Wnt/β-catenin signaling pathway via UCHL5

Li Xu, Liang Wang, Yaping Gan, Jiazhi Lin, Shuting Ning, Jinjin Deng, Yingxia Ning, Weifeng Feng,

https://doi.org/10.18632/aging.205991

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LncRNA DANCR promotes macrophage lipid accumulation through modulation of membrane cholesterol transporters

Guo-Jun Zhao, Yu Wang, Jun-Hong An, Wan-Ying Tang, Xiao-Dan Xu, Kun Ren,

https://doi.org/10.18632/aging.205992

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Genetic effect of thyroid function-related diseases on acute respiratory distress syndrome: a Mendelian randomization study

Peilong Li, Haifeng Liu, Feng Li, Mingze Sui, Kai Liu, Hongmin Fu,

https://doi.org/10.18632/aging.205996

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Integrated transcriptomics identifies prognostic significance and therapeutic response of cancer-associated fibroblast subpopulations in ovarian cancer

Shimeng Wan, Ziyan Liang, Shijie Yao, Anjin Wang, Xuelian Liu, Hao He, Hongbing Cai, Yang Gao, Hua Wang,

https://doi.org/10.18632/aging.205997

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Efficacy of Compound Danshen Dripping Pills in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a meta-analysis

Kuan Xu, Yan Zhu, Gang Hu,

https://doi.org/10.18632/aging.206000

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Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy

Siying Wang, Xuyu Chen, Xiaofei Zhang, Kang Wen, Xin Chen, Jingyao Gu, Juan Li, Zhaoxia Wang,

https://doi.org/10.18632/aging.206003

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Consensus clustering and novel risk score model construction based on m6A methylation regulators to evaluate the prognosis and tumor immune microenvironment of early-stage lung adenocarcinoma

Miao He, Yuxue Zhi, Chao Li, Changming Zhao, Guangquan Yang, Jing Lv, Hong You, Hai Huang, Xiaoyu Cao,

https://doi.org/10.18632/aging.206004

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PART1 facilitates tumorigenesis and inhibits ferroptosis by regulating the miR-490-3p/SLC7A11 axis in hepatocellular carcinoma

Decheng Li, Meiling Wan, Xiaoling Liu, Suvash Chandra Ojha, Yunjian Sheng, Yaling Li, Changfeng Sun, Cunliang Deng,

https://doi.org/10.18632/aging.206009

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FGA influences invasion and metastasis of hepatocellular carcinoma through the PI3K/AKT pathway

Xi Han, Zefeng Liu, Mengying Cui, Jie Lin, Yongzhi Li, Hanjiao Qin, Jiyao Sheng, Xuewen Zhang,

https://doi.org/10.18632/aging.206011

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Effect of body mass index on mortality for diabetic patients with aortic stenosis

Kai-Chun Chang, Li-Ting Ho, Kuan-Chih Huang, Jung-Chi Hsu, David Te-Wei Kuan, Ting-Tse Lin, Jen-Kuang Lee, Yen-Yun Yang, Shu-Lin Chuang, Lian-Yu Lin,

https://doi.org/10.18632/aging.206018

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High expression of circulating exosomal PD-L1 contributes to immune escape of hepatocellular carcinoma and immune clearance of chronic hepatitis B

Xiaoqing Lin, Hui Shao, Yongzhi Tang, Qiupeng Wang, Zhenyu Yang, Hongwei Wu, Tongjing Xing,

https://doi.org/10.18632/aging.206020

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Integrating single-cell RNA-seq to identify fibroblast-based molecular subtypes for predicting prognosis and therapeutic response in bladder cancer

Jia Wang, Zhiyong Tan, Yinglong Huang, Charles Li, Peiqin Zhan, Haifeng Wang, Haihao Li,

https://doi.org/10.18632/aging.206021

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Discovery of differentially expressed proteins for CAR-T therapy of ovarian cancers with a bioinformatics analysis

Dito Anurogo, Chao-Lien Liu, Yu-Chu Chang, Yu-Hsiang Chang, J. Timothy Qiu,

https://doi.org/10.18632/aging.206024

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Systematic characterization of the expression, prognosis and immune characteristics of PLOD family genes in breast cancer

Dan-Dan Wang, Lei Li, Yu-Qi Fu, Su-Jin Yang, Xiu Chen, Jun-Chen Hou, Qian Zhang, Xiao-Xue Tian, Jin-Hai Tang, Jian Zhang, He-Da Zhang,

https://doi.org/10.18632/aging.206029

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Effectiveness of vaginal probiotics Lactobacillus crispatus chen-01 in women with high-risk HPV infection: a prospective controlled pilot study

Yujuan Liu, Xiumiao Zhao, Fei Wu, Jie Chen, Juanzhen Luo, Chunling Wu, Tingtao Chen,

https://doi.org/10.18632/aging.206032

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Local anesthetic levobupivacaine induces ferroptosis and inhibits progression by up-regulating p53 in non-small cell lung cancer

Minghua Meng, Meiling Huang, Cuicui Liu, Jiming Wang, Weihua Ren, Shaomin Cui, Jianhua Gu, Jinlan Xie, Bin Ma, Guangzhu Yang, Shuncheng He,

https://doi.org/10.18632/aging.203138

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Identification of an immune subtype predicting survival risk and immune activity in hepatocellular carcinoma

Feng Zhao, Nuo Xu, Jiali Yang, Bo Li, Jianwei Shi, Yuanyuan Zheng, Longjin Xu,

https://doi.org/10.18632/aging.202953

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Circulating tumor DNA mutation analysis: advances in its application for early diagnosis of hepatocellular carcinoma and therapeutic efficacy monitoring

Jing Yang, Na Lin, Miaomiao Niu, Boshu Yin,

https://doi.org/10.18632/aging.205980

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Advance Publications

Editorials

Ze Zhang, Brock C. Christensen, Lucas A. Salas,

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Takuji Kawamura, Radak Zsolt, Mitsuru Higuchi, Kumpei Tanisawa,

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Research Perspectives

Taylor Russo, Markus Riessland,

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José Antonio Sánchez Milán, María Mulet, Aida Serra, Xavier Gallart-Palau,

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Research Papers

Karl Berner, Naci Oz, Alaattin Kaya, Animesh Acharjee, Jon Berner,

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Yongbin Di, Haolei Zhang, Bohao Zhang, Tianke Li, Dan Li,

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Guojing Chai, Yingbo Nan, Haili Zhao, Qingchuan Hu,

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Jing Zhang, Yindi Sun, Kai Tang, Huirong Xu, Junjuan Xiao, Yan Li,

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Chenglu Jiang, Shengke Zhang, Lai Jiang, Zipei Chen, Haiqing Chen, Jinbang Huang, Xuancheng Zhou, Jingyi Tang, Xinrui Gao, Hao Chi, Guanhu Yang, Shangke Huang,

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Jingyuan Dai, Jiahui Gao, Hongchao Dong,

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Yi Xu, Churuo Zeng, Jie Bin, Hua Tang, Wei Li,

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Yonghui Guo, Min Zhang, Yingrui Luo, Yingshi Li, Yanxia Xu, Nisha Wang,

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Jianxin Li, Ting Han, Jieyi Yang, Xin Wang, Yinchun Wang, Rui Yang, Qingqiang Yang,

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Zetao Chen, Li Cheng, Jing Zhang, Xing Cui,

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Yanbin Zhang, Tao Zhang, Long Chen, Zijun Guo, Xiaobing Jiang,

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Ruqiong Wei, Shihui Xiao, Shijian Zhao, Wenliang Guo, Ying Liu, Marìa del Mar Requena Mullor, Raquel Alarcòn Rodrìguez, Qingjun Wei, Yinteng Wu,

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Tianyu Wang, Bojian Lin, Boyu Cai, Zhiwen Cao, Caiquan Liang, Shunyu Wu, Enhong Xu, Li Li, Hu Peng, Huanhai Liu,

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Li Xu, Liang Wang, Yaping Gan, Jiazhi Lin, Shuting Ning, Jinjin Deng, Yingxia Ning, Weifeng Feng,

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Guo-Jun Zhao, Yu Wang, Jun-Hong An, Wan-Ying Tang, Xiao-Dan Xu, Kun Ren,

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