CHEBI:60937 - moricizine hydrochloride

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ChEBI Name moricizine hydrochloride
ChEBI ID CHEBI:60937
Definition A hydrochloride salt obtained from equimola amounts of moricizine and hydrogen chloride.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C22H26ClN3O4S
Net Charge 0
Average Mass 463.97800
Monoisotopic Mass 463.13326
InChI InChI=1S/C22H25N3O4S.ClH/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24;/h3-8,15H,2,9-14H2,1H3,(H,23,27);1H
InChIKey GAQAKFHSULJNAK-UHFFFAOYSA-N
SMILES [Cl-].CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CC[NH+]3CCOCC3)c2c1
Roles Classification
Application(s): anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
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ChEBI Ontology
Outgoing moricizine hydrochloride (CHEBI:60937) has part moricizine (CHEBI:6997)
moricizine hydrochloride (CHEBI:60937) has role anti-arrhythmia drug (CHEBI:38070)
moricizine hydrochloride (CHEBI:60937) is a hydrochloride (CHEBI:36807)
IUPAC Names
4-(3-{2-[(ethoxycarbonyl)amino]-10H-phenothiazin-10-yl}-3-oxopropyl)morpholin-4-ium chloride
ethyl {10-[3-(morpholin-4-yl)propanoyl]-10HH-phenothiazin-2-yl}carbamate hydrochloride
Synonyms Sources
ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate hydrochloride ChemIDplus
moracizine HCl ChEBI
moracizine hydrochloride ChEBI
moricizine HCl ChemIDplus
Brand Name Source
Ethmozine KEGG DRUG
Manual Xref Database
D02087 KEGG DRUG
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Registry Numbers Types Sources
29560-58-5 CAS Registry Number ChemIDplus
29560-58-5 CAS Registry Number KEGG DRUG
5212239 Reaxys Registry Number Reaxys
Last Modified
11 January 2011
General Comment
2011-01-11 A class I anti-arrhythmic, moricizine acts on the heart muscle to improve the heart's rhythm. It has potent local anaesthetic activity and membrane stabilizing effect, and is used as the hydrochloride in the treatment of serious symptomatic ventricular arrhythmias.