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- CreatorMichael Dante DiMartinoBryan KonietzkoStarsDee Bradley BakerZach Tyler EisenMae WhitmanIn a war-torn world of elemental powers, a young boy reawakens to undertake a dangerous mystic quest to fulfill his destiny as the Avatar, and bring peace to the world.
- CreatorJennifer FlackettAndrew GoldbergNick KrollStarsNick KrollJohn MulaneyJessi KleinTeenage friends find their lives upended by the wonders and horrors of puberty.
- StarsMichael CeraMary Elizabeth WinsteadSatya BhabhaScott Pilgrim meets the girl of his dreams, Ramona Flowers, only to find out her seven evil exes stand in the way of their love.
- CreatorSeth MacFarlaneDavid ZuckermanStarsSeth MacFarlaneAlex BorsteinSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightJulie KavnerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorTrey ParkerMatt StoneBrian GradenStarsTrey ParkerMatt StoneIsaac HayesFollows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- CreatorLoren BouchardJim DauteriveStarsH. Jon BenjaminDan MintzEugene MirmanBob Belcher runs a struggling burger shop with his wife and three children.
- CreatorRaphael Bob-WaksbergStarsWill ArnettAmy SedarisAlison BrieBoJack Horseman was the star of the hit television show "Horsin' Around" in the '80s and '90s, but now he's washed up, living in Hollywood, complaining about everything, and wearing colorful sweaters.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- CreatorMike BarkerSeth MacFarlaneMatt WeitzmanStarsSeth MacFarlaneWendy SchaalScott GrimesThe escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.
- CreatorAaron McGruderStarsRegina KingJohn WitherspoonGary Anthony WilliamsBrothers Huey and Riley Freeman experience a culture clash when they leave Chicago to move in with their grandfather in the suburbs.
- CreatorJ.G. QuintelStarsJ.G. QuintelWilliam SalyersSam MarinThe surreal misadventures of two best friends - a blue jay and a raccoon - as they seek to liven up their mundane jobs as groundskeepers at the local park.
- CreatorMatt GroeningJosh WeinsteinStarsAbbi JacobsonEric AndréNat FaxonPrincess Tiabeanie, 'Bean', is annoyed at her imminent arranged marriage to Prince Merkimer. Then she meets Luci, a demon, and Elfo, an elf, and things get rather exciting, and dangerous.
- CreatorShion TakeuchiAlex HirschStarsLizzy CaplanChristian SlaterClark DukeFor employees of the Deep State, conspiracies aren't just theories, they're fact. And keeping them a secret is a full-time job.
- CreatorSeth GreenMatthew SenreichMike FasoloStarsSeth GreenMatthew SenreichBreckin MeyerPop culture references fly thick and fast as stop-motion animation is featured in sketches lampooning everything from television movies to comic books.
- CreatorJennifer FlackettKelly GaluskaAndrew GoldbergStarsAidy BryantRandall ParkKeke PalmerA workplace comedy set in the world of the monsters from Big Mouth.
- CreatorMichael CusackZach HadelStarsMichael CusackZach HadelMarc M.In a colorful yet bizarre world, two employees at a small firm dedicated to making its customers smile discover that their jobs are rarely as simple as they seem.
- CreatorGlenn EichlerSusie LewisStarsTracy GrandstaffWendy HoopesJulian RebolledoA smart and cynical girl goes through teenage life as a proud outsider in a world of mainly idiotic adolescents and condescending adults.
- CreatorDave JeserMatt SilversteinJordan YoungStarsAdam CarollaJess HarnellAbbey McBrideA parody of reality shows cast with spoofs of several famous types of animated characters.
- CreatorTommy BlachaBrendon SmallStarsBrendon SmallTommy BlachaMark HamillThe epic and over-the-top adventures of Dethklok, the world's most successful death metal band.
- CreatorRichard AppelMike HenrySeth MacFarlaneStarsMike HenrySanaa LathanKevin Michael RichardsonCleveland Brown moves back to his hometown in Virginia with his son, where he finds his high school sweetheart and her two troublemaking kids.
- CreatorDino StamatopoulosStarsCarolyn LawrenceScott AdsitBritta PhillipsA parody of past religious-geared animated shows starring Orel, an optimistic God-fearing young boy in a world of cynicism.
- CreatorBill LawrencePhil LordChristopher MillerStarsNeil CaseyAyo EdebiriWill ForteHistorical figures who have been cloned and placed back in high school, including Abraham Lincoln, Cleopatra, Joan of Arc, John F. Kennedy and more, as they face the trials of normal teenage life.
- CreatorBill LawrencePhil LordChristopher MillerStarsWill FortePhil LordMichael McDonaldThe greatest minds of the world have been cloned, and are now attending high school together.
- CreatorLisa HanawaltStarsTiffany HaddishAli WongSteven YeunThe story of two 30-year old bird women who live in the same apartment building.